JP2016500002A5 - - Google Patents
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- JP2016500002A5 JP2016500002A5 JP2015535848A JP2015535848A JP2016500002A5 JP 2016500002 A5 JP2016500002 A5 JP 2016500002A5 JP 2015535848 A JP2015535848 A JP 2015535848A JP 2015535848 A JP2015535848 A JP 2015535848A JP 2016500002 A5 JP2016500002 A5 JP 2016500002A5
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- 238000000034 method Methods 0.000 claims description 115
- 150000007523 nucleic acids Chemical class 0.000 claims description 42
- 108020004707 nucleic acids Proteins 0.000 claims description 35
- 102000039446 nucleic acids Human genes 0.000 claims description 35
- 238000011002 quantification Methods 0.000 claims description 17
- 238000012545 processing Methods 0.000 claims description 15
- 230000003321 amplification Effects 0.000 claims description 12
- 238000001514 detection method Methods 0.000 claims description 12
- 238000003199 nucleic acid amplification method Methods 0.000 claims description 12
- 238000007619 statistical method Methods 0.000 claims description 6
- 238000002834 transmittance Methods 0.000 claims description 6
- 238000007405 data analysis Methods 0.000 claims description 5
- 238000003705 background correction Methods 0.000 claims description 4
- 230000002045 lasting effect Effects 0.000 claims description 4
- 230000003287 optical effect Effects 0.000 claims description 4
- 230000000903 blocking effect Effects 0.000 claims description 3
- 238000001506 fluorescence spectroscopy Methods 0.000 claims description 3
- 238000003556 assay Methods 0.000 claims description 2
- 238000001914 filtration Methods 0.000 claims description 2
- 230000001404 mediated effect Effects 0.000 claims description 2
- 238000010295 mobile communication Methods 0.000 claims description 2
- 239000000523 sample Substances 0.000 description 69
- 108090000623 proteins and genes Proteins 0.000 description 10
- 108091028043 Nucleic acid sequence Proteins 0.000 description 9
- 241000700605 Viruses Species 0.000 description 3
- 239000007850 fluorescent dye Substances 0.000 description 3
- 230000035772 mutation Effects 0.000 description 3
- 241000894006 Bacteria Species 0.000 description 2
- 238000003745 diagnosis Methods 0.000 description 2
- 208000035143 Bacterial infection Diseases 0.000 description 1
- 208000026350 Inborn Genetic disease Diseases 0.000 description 1
- 241001465754 Metazoa Species 0.000 description 1
- 208000036142 Viral infection Diseases 0.000 description 1
- 238000004458 analytical method Methods 0.000 description 1
- 230000001580 bacterial effect Effects 0.000 description 1
- 208000022362 bacterial infectious disease Diseases 0.000 description 1
- DEGAKNSWVGKMLS-UHFFFAOYSA-N calcein Chemical group O1C(=O)C2=CC=CC=C2C21C1=CC(CN(CC(O)=O)CC(O)=O)=C(O)C=C1OC1=C2C=C(CN(CC(O)=O)CC(=O)O)C(O)=C1 DEGAKNSWVGKMLS-UHFFFAOYSA-N 0.000 description 1
- 238000013480 data collection Methods 0.000 description 1
- 201000010099 disease Diseases 0.000 description 1
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 description 1
- 208000016361 genetic disease Diseases 0.000 description 1
- 238000005259 measurement Methods 0.000 description 1
- 229960002378 oftasceine Drugs 0.000 description 1
- 102000004169 proteins and genes Human genes 0.000 description 1
- 230000035484 reaction time Effects 0.000 description 1
- 239000013074 reference sample Substances 0.000 description 1
- 241000894007 species Species 0.000 description 1
- 238000001228 spectrum Methods 0.000 description 1
- 238000002211 ultraviolet spectrum Methods 0.000 description 1
- 230000009385 viral infection Effects 0.000 description 1
- 230000003612 virological effect Effects 0.000 description 1
- 229910052724 xenon Inorganic materials 0.000 description 1
- FHNFHKCVQCLJFQ-UHFFFAOYSA-N xenon atom Chemical compound [Xe] FHNFHKCVQCLJFQ-UHFFFAOYSA-N 0.000 description 1
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201261710454P | 2012-10-05 | 2012-10-05 | |
| US61/710,454 | 2012-10-05 | ||
| PCT/US2013/063594 WO2014055963A1 (en) | 2012-10-05 | 2013-10-04 | Methods and systems for microfluidics imaging and analysis |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2016500002A JP2016500002A (ja) | 2016-01-07 |
| JP2016500002A5 true JP2016500002A5 (https=) | 2016-11-10 |
Family
ID=50435499
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2015535848A Pending JP2016500002A (ja) | 2012-10-05 | 2013-10-04 | マイクロ流体イメージングおよび分析のための方法およびシステム |
Country Status (8)
| Country | Link |
|---|---|
| US (1) | US20150247190A1 (https=) |
| EP (1) | EP2904116A4 (https=) |
| JP (1) | JP2016500002A (https=) |
| CN (1) | CN104870652A (https=) |
| AU (1) | AU2013326786A1 (https=) |
| CA (1) | CA2887206A1 (https=) |
| HK (1) | HK1211990A1 (https=) |
| WO (1) | WO2014055963A1 (https=) |
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| EP3058100A4 (en) | 2013-10-18 | 2017-04-19 | California Institute of Technology | Enhanced nucleic acid identification and detection |
| US10260111B1 (en) | 2014-01-20 | 2019-04-16 | Brett Eric Etchebarne | Method of detecting sepsis-related microorganisms and detecting antibiotic-resistant sepsis-related microorganisms in a fluid sample |
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| US9953415B2 (en) | 2014-12-03 | 2018-04-24 | Tata Consultancy Services Limited | System and method for quantification of Escherichia coli bacteria in water |
| WO2016094459A2 (en) * | 2014-12-09 | 2016-06-16 | Berkeley Lights, Inc. | Automated detection and repositioning of micro-objects in microfluidic devices |
| US10998088B2 (en) | 2014-12-11 | 2021-05-04 | Hyris Limited | Method for managing the protocols used by devices for diagnostic and clinical analysis and results obtained from such devices |
| EP4029606A1 (en) | 2014-12-31 | 2022-07-20 | Visby Medical, Inc. | Molecular diagnostic testing |
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| US10519493B2 (en) | 2015-06-22 | 2019-12-31 | Fluxergy, Llc | Apparatus and method for image analysis of a fluid sample undergoing a polymerase chain reaction (PCR) |
| US11371091B2 (en) | 2015-06-22 | 2022-06-28 | Fluxergy, Inc. | Device for analyzing a fluid sample and use of test card with same |
| US10214772B2 (en) | 2015-06-22 | 2019-02-26 | Fluxergy, Llc | Test card for assay and method of manufacturing same |
| EP4227067A3 (en) * | 2015-06-22 | 2024-01-10 | FluxErgy, Inc. | Device for analyzing a fluid sample and use of test card with same |
| WO2017025984A1 (en) * | 2015-08-07 | 2017-02-16 | Council Of Scientific And Industrial Research | Smartphone integrated real - time molecular diagnostic device |
| WO2017079696A1 (en) * | 2015-11-06 | 2017-05-11 | California Institute Of Technology | Devices and methods for direct visual detection and readout of single nucleic acid molecules |
| US10718003B2 (en) * | 2015-12-31 | 2020-07-21 | Roche Molecular Systems, Inc. | Detecting an analyte in a flash and glow reaction |
| WO2017119340A1 (ja) * | 2016-01-05 | 2017-07-13 | 浜松ホトニクス株式会社 | 生体観察方法及び生体観察装置 |
| JP7064665B2 (ja) | 2016-03-07 | 2022-05-11 | ファーザー フラナガンズ ボーイズ ホーム ドゥーイング ビジネス アズ ボーイズ タウン ナショナル リサーチ ホスピタル | 非侵襲的分子対照 |
| EP3429543B1 (en) | 2016-03-14 | 2024-11-20 | Pfizer Inc. | Selectively vented biological assay devices and associated methods |
| ES2927062T3 (es) | 2016-03-14 | 2022-11-02 | Lucira Health Inc | Dispositivos y procedimientos para modificar propiedades ópticas |
| JP6949864B2 (ja) | 2016-03-14 | 2021-10-13 | ルシラ ヘルス インコーポレイテッド | 生物学的アッセイ試料調製および送り出しのための装置および方法 |
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| US11168347B2 (en) | 2016-09-23 | 2021-11-09 | California Institute Of Technology | Digital quantification of DNA replication and/or chromosome segregation based determination of antimicrobial susceptibility |
| US9857372B1 (en) * | 2016-10-17 | 2018-01-02 | Reliant Immune Diagnostics, LLC | Arbovirus indicative birth defect risk test |
| CN106754335B (zh) * | 2016-11-22 | 2019-05-17 | 上海海洋大学 | 一种等温核酸扩增芯片 |
| US10218900B2 (en) * | 2016-11-30 | 2019-02-26 | Ncr Corporation | Document reorientation processing |
| CN110268414B (zh) * | 2016-12-01 | 2023-08-01 | 伯克利之光生命科技公司 | 微流体装置中的微物体的自动检测和重新定位 |
| US10324041B2 (en) * | 2016-12-21 | 2019-06-18 | Abbott Japan Co., Ltd. | Optical imaging system using lateral illumination for digital assays |
| US11047854B2 (en) | 2017-02-06 | 2021-06-29 | Abbott Japan Llc | Methods for reducing noise in signal-generating digital assays |
| EP3615924A1 (en) * | 2017-03-13 | 2020-03-04 | Zoetis Services LLC | A lateral flow test system |
| US10146909B2 (en) * | 2017-04-06 | 2018-12-04 | Diassess Inc. | Image-based disease diagnostics using a mobile device |
| US11080848B2 (en) | 2017-04-06 | 2021-08-03 | Lucira Health, Inc. | Image-based disease diagnostics using a mobile device |
| CN113777011B (zh) | 2017-09-14 | 2024-11-19 | 辉瑞公司 | 具有电子读出的复用生物测定装置 |
| US10549275B2 (en) | 2017-09-14 | 2020-02-04 | Lucira Health, Inc. | Multiplexed biological assay device with electronic readout |
| US11953479B2 (en) | 2017-10-06 | 2024-04-09 | The Research Foundation For The State University Of New York | Selective optical aqueous and non-aqueous detection of free sulfites |
| WO2019075264A1 (en) | 2017-10-11 | 2019-04-18 | California Institute Of Technology | ANTIBIOSENSITIVITY OF MICROORGANISMS AND COMPOSITIONS, METHODS AND ASSOCIATED SYSTEMS |
| US12448655B2 (en) | 2017-10-11 | 2025-10-21 | California Institute Of Technology | Antibiotic susceptibility of microorganisms and related methods and systems |
| SG11202002931VA (en) | 2017-11-09 | 2020-04-29 | Visby Medical Inc | Portable molecular diagnostic device and methods for the detection of target viruses |
| WO2019169287A1 (en) * | 2018-03-02 | 2019-09-06 | Teleflex Medical Incorporated | Infection detection systems and methods |
| EP3762708A4 (en) * | 2018-03-05 | 2022-01-05 | Mao Foodtech Ltd. | SYSTEM, DEVICE AND METHOD FOR IDENTIFYING AND MONITORING A BREAST MILK COMPOSITION |
| US11060968B2 (en) | 2018-03-30 | 2021-07-13 | International Business Machines Corporation | Mobile chemical analysis |
| WO2019221676A1 (en) * | 2018-05-15 | 2019-11-21 | Vivosens Bi̇yoteknoloji̇ Ar-Ge Sanayi̇ & Ti̇caret Ltd. Şti̇. | Analysis of urine test strips with mobile camera analysys and providing recommendation by customising data |
| CN108977558A (zh) * | 2018-08-24 | 2018-12-11 | 暨南大学 | 基于数字lamp技术检测金黄色葡萄球菌的引物及其试剂盒与方法 |
| CN112823276A (zh) * | 2018-10-09 | 2021-05-18 | 卢西拉健康公司 | 基于消费者的疾病诊断 |
| USD907232S1 (en) | 2018-12-21 | 2021-01-05 | Lucira Health, Inc. | Medical testing device |
| JP2022530323A (ja) | 2019-04-28 | 2022-06-29 | ビスビュー メディカル，インコーポレイテッド | デジタル検出能力および無線接続性を有する分子診断デバイス |
| EP3983811A4 (en) * | 2019-07-01 | 2022-08-17 | Mantiscope Tibbi Cihazlar Arastirma ve Gelistirme Ltd. Sti. | SYSTEM AND METHODS FOR DIGITALIZATION, ANALYSIS AND STORAGE OF BIOLOGICAL SAMPLES |
| CN110643483B (zh) * | 2019-09-06 | 2023-04-14 | 上海交通大学 | 一种在微流控芯片上生成液滴阵列的方法 |
| CN111197003B (zh) * | 2019-12-26 | 2023-08-25 | 中国科学院合肥物质科学研究院 | 一种基于智能手机的集成核酸提取扩增检测的分析装置及方法 |
| CA3170420A1 (en) * | 2020-02-10 | 2021-08-19 | Emerging Viral Diagnostics (Hk) Limited | Point-of-care microfluidic in vitro diagnostic system |
| KR102298771B1 (ko) * | 2020-02-21 | 2021-09-07 | (주)오상헬스케어 | 형광염료의 종류에 따라 촬영방식을 선택하는 크로마토그래피 검사장치 및 그 제어방법 |
| US10968493B1 (en) * | 2020-03-12 | 2021-04-06 | New England Biolabs, Inc. | Rapid diagnostic test using colorimetric LAMP |
| US11732315B2 (en) | 2020-03-12 | 2023-08-22 | New England Biolabs, Inc. | Rapid diagnostic test for lamp |
| US11345970B2 (en) * | 2020-03-12 | 2022-05-31 | New England Biolabs, Inc. | Rapid diagnostic test for LAMP |
| USD953561S1 (en) | 2020-05-05 | 2022-05-31 | Lucira Health, Inc. | Diagnostic device with LED display |
| USD962470S1 (en) | 2020-06-03 | 2022-08-30 | Lucira Health, Inc. | Assay device with LCD display |
| US11709819B2 (en) | 2020-09-30 | 2023-07-25 | International Business Machines Corporation | Validating test results using a blockchain network |
| US20220283088A1 (en) * | 2021-02-03 | 2022-09-08 | Joshua David Silver | Viral load tester and applications thereof |
| CN113372559B (zh) * | 2021-06-21 | 2023-09-15 | 福建立亚化学有限公司 | 一种液态聚碳硅烷先驱体材料的生产方法及其装置 |
| US12275066B2 (en) | 2021-10-05 | 2025-04-15 | Nikon Corporation | Systems and methods for improved melting in three-dimensional printing processes |
| CN114047187B (zh) * | 2021-11-04 | 2023-10-10 | 温州医科大学 | 一种使用raw图像测量有色溶液物质浓度的方法 |
| CN113932948B (zh) * | 2021-11-15 | 2023-07-25 | 江西省永盛园艺股份有限公司 | 一种多肉植物种植用水分温度监测装置 |
| US12555691B2 (en) | 2022-02-22 | 2026-02-17 | Hyperspectral Corp. | Systems and methods for detecting pathogens using spectrometer scans |
| US12276600B2 (en) | 2022-02-22 | 2025-04-15 | Hyperspectral Corp. | Systems and methods for detecting foodborne pathogens using spectral analysis |
| US12442768B2 (en) * | 2022-09-14 | 2025-10-14 | The Trustees Of The University Of Pennsylvania | Photostimulation device and methods of using the same |
| TR2022017709A1 (tr) * | 2022-11-23 | 2024-06-21 | Izmir Biyotip Ve Genom Merkezi | FMF (Ailevi Akdeniz Ateşi) Hastalığı Tanısı İçin Biyosensör Sistemi |
| CN116179321B (zh) * | 2023-04-27 | 2023-06-23 | 北京慧荣和科技有限公司 | 气溶胶采样器以及报警器的评测装置 |
| US11914504B1 (en) * | 2023-06-27 | 2024-02-27 | Starbucks Corporation | Performing physical experiments based on automatically-generated testing scripts |
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| Publication number | Priority date | Publication date | Assignee | Title |
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| WO1996031522A1 (en) * | 1995-04-03 | 1996-10-10 | New York University | Methods for measuring physical characteristics of nucleic acids by microscopic imaging |
| US20020050518A1 (en) * | 1997-12-08 | 2002-05-02 | Roustaei Alexander R. | Sensor array |
| US7640083B2 (en) * | 2002-11-22 | 2009-12-29 | Monroe David A | Record and playback system for aircraft |
| US6522775B2 (en) * | 2001-03-28 | 2003-02-18 | Alan C. Nelson | Apparatus and method for imaging small objects in a flow stream using optical tomography |
| WO2003100422A1 (en) * | 2002-05-28 | 2003-12-04 | Japan Genome Solutions, Inc. | Dna microarray data processing method, dna microarray data processing system, dna microarray data processor, program and recording medium |
| EP1608952B1 (en) * | 2002-12-20 | 2016-08-10 | Life Technologies Corporation | Assay apparatus and method using microfluidic arrays |
| JP4771521B2 (ja) * | 2005-08-09 | 2011-09-14 | キヤノン株式会社 | 標識された核酸プライマー結合物体、その製造方法、ならびにその用途 |
| TR201910868T4 (tr) * | 2006-02-02 | 2019-08-21 | Univ Leland Stanford Junior | Dijital analizle invazif olmayan fetal genetik tarama. |
| EP2080025A4 (en) * | 2006-10-27 | 2011-12-07 | Montecito Bio Sciences Ltd | PORTABLE DEVICE FOR IMPROVED SAMPLE ANALYSIS |
| CN100465990C (zh) * | 2006-11-17 | 2009-03-04 | 东华大学 | 一种面向微流控芯片的智能定位方法 |
| DK2291640T3 (en) * | 2008-05-20 | 2019-03-11 | Univ Health Network | Device and method for fluorescence-based imaging and monitoring |
| WO2010053980A2 (en) * | 2008-11-04 | 2010-05-14 | The Johns Hopkins University | Dna integrity assay (dia) for cancer diagnostics, using confocal fluorescence spectroscopy |
| US9347947B2 (en) * | 2009-03-12 | 2016-05-24 | Siemens Healthcare Diagnostics Inc. | Immunoassays employing non-particulate chemiluminescent reagent |
| US9415392B2 (en) * | 2009-03-24 | 2016-08-16 | The University Of Chicago | Slip chip device and methods |
| WO2010148252A1 (en) * | 2009-06-17 | 2010-12-23 | Jody Vykoukal | Method and apparatus for quantitative microimaging |
| TW201209158A (en) * | 2010-06-17 | 2012-03-01 | Geneasys Pty Ltd | LOC device for genetic analysis with dialysis, chemical lysis and tandem nucleic acid amplification |
| CN102004161B (zh) * | 2010-11-09 | 2012-08-15 | 华中科技大学 | 一种微阵列反应装置 |
| GB201105474D0 (en) * | 2011-03-31 | 2011-05-18 | Albagaia Ltd | Testing apparatus |
| CN104630373B (zh) * | 2015-02-13 | 2017-11-21 | 博奥生物集团有限公司 | 一种微流控芯片核酸快速并行检测方法及系统 |
-
2013
- 2013-10-04 CN CN201380063799.2A patent/CN104870652A/zh active Pending
- 2013-10-04 WO PCT/US2013/063594 patent/WO2014055963A1/en not_active Ceased
- 2013-10-04 EP EP13844115.9A patent/EP2904116A4/en not_active Withdrawn
- 2013-10-04 AU AU2013326786A patent/AU2013326786A1/en not_active Abandoned
- 2013-10-04 JP JP2015535848A patent/JP2016500002A/ja active Pending
- 2013-10-04 CA CA2887206A patent/CA2887206A1/en not_active Abandoned
- 2013-10-04 HK HK15112866.9A patent/HK1211990A1/xx unknown
- 2013-10-04 US US14/433,602 patent/US20150247190A1/en not_active Abandoned
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