JP2016500002A5 - - Google Patents
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- JP2016500002A5 JP2016500002A5 JP2015535848A JP2015535848A JP2016500002A5 JP 2016500002 A5 JP2016500002 A5 JP 2016500002A5 JP 2015535848 A JP2015535848 A JP 2015535848A JP 2015535848 A JP2015535848 A JP 2015535848A JP 2016500002 A5 JP2016500002 A5 JP 2016500002A5
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- 238000000034 method Methods 0.000 claims description 115
- 150000007523 nucleic acids Chemical class 0.000 claims description 42
- 108020004707 nucleic acids Proteins 0.000 claims description 35
- 102000039446 nucleic acids Human genes 0.000 claims description 35
- 238000011002 quantification Methods 0.000 claims description 17
- 238000012545 processing Methods 0.000 claims description 15
- 230000003321 amplification Effects 0.000 claims description 12
- 238000001514 detection method Methods 0.000 claims description 12
- 238000003199 nucleic acid amplification method Methods 0.000 claims description 12
- 238000007619 statistical method Methods 0.000 claims description 6
- 238000002834 transmittance Methods 0.000 claims description 6
- 238000007405 data analysis Methods 0.000 claims description 5
- 238000003705 background correction Methods 0.000 claims description 4
- 230000002045 lasting effect Effects 0.000 claims description 4
- 230000003287 optical effect Effects 0.000 claims description 4
- 230000000903 blocking effect Effects 0.000 claims description 3
- 238000001506 fluorescence spectroscopy Methods 0.000 claims description 3
- 238000003556 assay Methods 0.000 claims description 2
- 238000001914 filtration Methods 0.000 claims description 2
- 230000001404 mediated effect Effects 0.000 claims description 2
- 238000010295 mobile communication Methods 0.000 claims description 2
- 239000000523 sample Substances 0.000 description 69
- 108090000623 proteins and genes Proteins 0.000 description 10
- 108091028043 Nucleic acid sequence Proteins 0.000 description 9
- 241000700605 Viruses Species 0.000 description 3
- 239000007850 fluorescent dye Substances 0.000 description 3
- 230000035772 mutation Effects 0.000 description 3
- 241000894006 Bacteria Species 0.000 description 2
- 238000003745 diagnosis Methods 0.000 description 2
- 208000035143 Bacterial infection Diseases 0.000 description 1
- 208000026350 Inborn Genetic disease Diseases 0.000 description 1
- 241001465754 Metazoa Species 0.000 description 1
- 208000036142 Viral infection Diseases 0.000 description 1
- 238000004458 analytical method Methods 0.000 description 1
- 230000001580 bacterial effect Effects 0.000 description 1
- 208000022362 bacterial infectious disease Diseases 0.000 description 1
- DEGAKNSWVGKMLS-UHFFFAOYSA-N calcein Chemical group O1C(=O)C2=CC=CC=C2C21C1=CC(CN(CC(O)=O)CC(O)=O)=C(O)C=C1OC1=C2C=C(CN(CC(O)=O)CC(=O)O)C(O)=C1 DEGAKNSWVGKMLS-UHFFFAOYSA-N 0.000 description 1
- 238000013480 data collection Methods 0.000 description 1
- 201000010099 disease Diseases 0.000 description 1
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 description 1
- 208000016361 genetic disease Diseases 0.000 description 1
- 238000005259 measurement Methods 0.000 description 1
- 229960002378 oftasceine Drugs 0.000 description 1
- 102000004169 proteins and genes Human genes 0.000 description 1
- 230000035484 reaction time Effects 0.000 description 1
- 239000013074 reference sample Substances 0.000 description 1
- 241000894007 species Species 0.000 description 1
- 238000001228 spectrum Methods 0.000 description 1
- 238000002211 ultraviolet spectrum Methods 0.000 description 1
- 230000009385 viral infection Effects 0.000 description 1
- 230000003612 virological effect Effects 0.000 description 1
- 229910052724 xenon Inorganic materials 0.000 description 1
- FHNFHKCVQCLJFQ-UHFFFAOYSA-N xenon atom Chemical compound [Xe] FHNFHKCVQCLJFQ-UHFFFAOYSA-N 0.000 description 1
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201261710454P | 2012-10-05 | 2012-10-05 | |
| US61/710,454 | 2012-10-05 | ||
| PCT/US2013/063594 WO2014055963A1 (en) | 2012-10-05 | 2013-10-04 | Methods and systems for microfluidics imaging and analysis |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2016500002A JP2016500002A (ja) | 2016-01-07 |
| JP2016500002A5 true JP2016500002A5 (https=) | 2016-11-10 |
Family
ID=50435499
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2015535848A Pending JP2016500002A (ja) | 2012-10-05 | 2013-10-04 | マイクロ流体イメージングおよび分析のための方法およびシステム |
Country Status (8)
| Country | Link |
|---|---|
| US (1) | US20150247190A1 (https=) |
| EP (1) | EP2904116A4 (https=) |
| JP (1) | JP2016500002A (https=) |
| CN (1) | CN104870652A (https=) |
| AU (1) | AU2013326786A1 (https=) |
| CA (1) | CA2887206A1 (https=) |
| HK (1) | HK1211990A1 (https=) |
| WO (1) | WO2014055963A1 (https=) |
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| US10866184B2 (en) * | 2015-11-06 | 2020-12-15 | California Institute Of Technology | Devices and methods for direct visual detection and readout of single nucleic acid molecules |
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| DK3430378T3 (da) | 2016-03-14 | 2022-10-24 | Lucira Health Inc | Indretninger og fremgangsmåder til modifikation af optiske egenskaber |
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| US11168347B2 (en) | 2016-09-23 | 2021-11-09 | California Institute Of Technology | Digital quantification of DNA replication and/or chromosome segregation based determination of antimicrobial susceptibility |
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| US10324041B2 (en) | 2016-12-21 | 2019-06-18 | Abbott Japan Co., Ltd. | Optical imaging system using lateral illumination for digital assays |
| US11047854B2 (en) | 2017-02-06 | 2021-06-29 | Abbott Japan Llc | Methods for reducing noise in signal-generating digital assays |
| EP3615924A1 (en) * | 2017-03-13 | 2020-03-04 | Zoetis Services LLC | A lateral flow test system |
| US11080848B2 (en) | 2017-04-06 | 2021-08-03 | Lucira Health, Inc. | Image-based disease diagnostics using a mobile device |
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| CN113777011B (zh) | 2017-09-14 | 2024-11-19 | 辉瑞公司 | 具有电子读出的复用生物测定装置 |
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| WO2019075264A1 (en) | 2017-10-11 | 2019-04-18 | California Institute Of Technology | ANTIBIOSENSITIVITY OF MICROORGANISMS AND COMPOSITIONS, METHODS AND ASSOCIATED SYSTEMS |
| US12448655B2 (en) | 2017-10-11 | 2025-10-21 | California Institute Of Technology | Antibiotic susceptibility of microorganisms and related methods and systems |
| KR20200079264A (ko) | 2017-11-09 | 2020-07-02 | 비스비 메디컬, 인코포레이티드 | 표적 바이러스 검출을 위한 휴대용 분자 진단 디바이스 및 방법 |
| CA3092684A1 (en) * | 2018-03-02 | 2019-09-06 | Teleflex Medical Incorporated | Infection detection systems and methods |
| EP3762708A4 (en) * | 2018-03-05 | 2022-01-05 | Mao Foodtech Ltd. | SYSTEM, DEVICE AND METHOD FOR IDENTIFYING AND MONITORING A BREAST MILK COMPOSITION |
| US11060968B2 (en) | 2018-03-30 | 2021-07-13 | International Business Machines Corporation | Mobile chemical analysis |
| US20210208081A1 (en) * | 2018-05-15 | 2021-07-08 | Vivosens Inc | Analysis of urine test strips with mobile camera analysys and providing recommendation by customising data |
| CN108977558A (zh) * | 2018-08-24 | 2018-12-11 | 暨南大学 | 基于数字lamp技术检测金黄色葡萄球菌的引物及其试剂盒与方法 |
| MX2021004018A (es) * | 2018-10-09 | 2021-06-23 | Lucira Health Inc | Diagnostico de enfermedades basado en el consumidor. |
| USD907232S1 (en) | 2018-12-21 | 2021-01-05 | Lucira Health, Inc. | Medical testing device |
| WO2020223257A1 (en) | 2019-04-28 | 2020-11-05 | Visby Medical, Inc. | Molecular diagnostic devices with digital detection capability and wireless connectivity |
| EP3983811A4 (en) * | 2019-07-01 | 2022-08-17 | Mantiscope Tibbi Cihazlar Arastirma ve Gelistirme Ltd. Sti. | SYSTEM AND METHODS FOR DIGITALIZATION, ANALYSIS AND STORAGE OF BIOLOGICAL SAMPLES |
| CN110643483B (zh) * | 2019-09-06 | 2023-04-14 | 上海交通大学 | 一种在微流控芯片上生成液滴阵列的方法 |
| CN111197003B (zh) * | 2019-12-26 | 2023-08-25 | 中国科学院合肥物质科学研究院 | 一种基于智能手机的集成核酸提取扩增检测的分析装置及方法 |
| US20230108296A1 (en) * | 2020-02-10 | 2023-04-06 | Emerging Viral Diagnostics (Hk) Limited | Point-of-care microfluidic in vitro diagnostic system |
| KR102298771B1 (ko) * | 2020-02-21 | 2021-09-07 | (주)오상헬스케어 | 형광염료의 종류에 따라 촬영방식을 선택하는 크로마토그래피 검사장치 및 그 제어방법 |
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| USD953561S1 (en) | 2020-05-05 | 2022-05-31 | Lucira Health, Inc. | Diagnostic device with LED display |
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| US20220283088A1 (en) * | 2021-02-03 | 2022-09-08 | Joshua David Silver | Viral load tester and applications thereof |
| CN113372559B (zh) * | 2021-06-21 | 2023-09-15 | 福建立亚化学有限公司 | 一种液态聚碳硅烷先驱体材料的生产方法及其装置 |
| US12275066B2 (en) | 2021-10-05 | 2025-04-15 | Nikon Corporation | Systems and methods for improved melting in three-dimensional printing processes |
| CN114047187B (zh) * | 2021-11-04 | 2023-10-10 | 温州医科大学 | 一种使用raw图像测量有色溶液物质浓度的方法 |
| CN113932948B (zh) * | 2021-11-15 | 2023-07-25 | 江西省永盛园艺股份有限公司 | 一种多肉植物种植用水分温度监测装置 |
| WO2023164520A1 (en) * | 2022-02-22 | 2023-08-31 | Hyperspectral Corp. | Systems and methods for detecting foodborne pathogens using spectral analysis |
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| US12442768B2 (en) * | 2022-09-14 | 2025-10-14 | The Trustees Of The University Of Pennsylvania | Photostimulation device and methods of using the same |
| TR2022017709A1 (tr) * | 2022-11-23 | 2024-06-21 | Izmir Biyotip Ve Genom Merkezi | FMF (Ailevi Akdeniz Ateşi) Hastalığı Tanısı İçin Biyosensör Sistemi |
| CN116179321B (zh) * | 2023-04-27 | 2023-06-23 | 北京慧荣和科技有限公司 | 气溶胶采样器以及报警器的评测装置 |
| US11914504B1 (en) * | 2023-06-27 | 2024-02-27 | Starbucks Corporation | Performing physical experiments based on automatically-generated testing scripts |
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| WO1996031522A1 (en) * | 1995-04-03 | 1996-10-10 | New York University | Methods for measuring physical characteristics of nucleic acids by microscopic imaging |
| US20020050518A1 (en) * | 1997-12-08 | 2002-05-02 | Roustaei Alexander R. | Sensor array |
| US6522775B2 (en) * | 2001-03-28 | 2003-02-18 | Alan C. Nelson | Apparatus and method for imaging small objects in a flow stream using optical tomography |
| WO2003100422A1 (en) * | 2002-05-28 | 2003-12-04 | Japan Genome Solutions, Inc. | Dna microarray data processing method, dna microarray data processing system, dna microarray data processor, program and recording medium |
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| EP3591068A1 (en) * | 2006-02-02 | 2020-01-08 | The Board of Trustees of the Leland Stanford Junior University | Non-invasive fetal genetic screening by digital analysis |
| CN101558302B (zh) * | 2006-10-27 | 2013-11-06 | 蒙泰西托生物科学有限公司 | 用于改进的取样分析的便携设备 |
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| JP5766178B2 (ja) * | 2009-03-24 | 2015-08-19 | ザ・ユニバーシティ・オブ・シカゴＴｈｅ Ｕｎｉｖｅｒｓｉｔｙ Ｏｆ Ｃｈｉｃａｇｏ | ＳｌｉｐＣｈｉｐ装置および方法 |
| WO2010148252A1 (en) * | 2009-06-17 | 2010-12-23 | Jody Vykoukal | Method and apparatus for quantitative microimaging |
| TW201219776A (en) * | 2010-06-17 | 2012-05-16 | Geneasys Pty Ltd | Microfluidic device with conductivity sensor |
| CN102004161B (zh) * | 2010-11-09 | 2012-08-15 | 华中科技大学 | 一种微阵列反应装置 |
| GB201105474D0 (en) * | 2011-03-31 | 2011-05-18 | Albagaia Ltd | Testing apparatus |
| CN104630373B (zh) * | 2015-02-13 | 2017-11-21 | 博奥生物集团有限公司 | 一种微流控芯片核酸快速并行检测方法及系统 |
-
2013
- 2013-10-04 US US14/433,602 patent/US20150247190A1/en not_active Abandoned
- 2013-10-04 JP JP2015535848A patent/JP2016500002A/ja active Pending
- 2013-10-04 CN CN201380063799.2A patent/CN104870652A/zh active Pending
- 2013-10-04 CA CA2887206A patent/CA2887206A1/en not_active Abandoned
- 2013-10-04 HK HK15112866.9A patent/HK1211990A1/xx unknown
- 2013-10-04 WO PCT/US2013/063594 patent/WO2014055963A1/en not_active Ceased
- 2013-10-04 EP EP13844115.9A patent/EP2904116A4/en not_active Withdrawn
- 2013-10-04 AU AU2013326786A patent/AU2013326786A1/en not_active Abandoned
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