JP2016179434A - Medical purified water production apparatus, production method of medical purified water, and filter - Google Patents

Abstract

PROBLEM TO BE SOLVED: To provide a medical purified water production apparatus or the like in which control in allowing water to be treated to permeate becomes easier even in the case where a filter is in a multistage filtering configuration in which permeated water is not temporarily stored in an intermediate tank or the like, and a plurality of filtering means are connected in series.SOLUTION: A purified water production unit 1 that purifies water to be treated to produce purified water being pharmaceutical water comprises: an RO device 62 which allows water to be treated to permeate a reverse osmosis membrane to purify the water; an RO device 64 which allows first permeated water, which passed through the RO device 62, to permeate the reverse osmosis membrane without storing the permeated water to further purify the water; a pump 61 which sends out the water to be treated to the RO device 62; a pump 63 which sends out the first permeated water to the RO device 64; and a control unit 80 which controls the pump 61 to bring the pressure of the first permeated water within a predetermined range, and controls the pump 63 to bring the flow rate of second permeated water which permeated the RO device 64 within a predetermined range.SELECTED DRAWING: Figure 1

Description

  The present invention relates to a device for producing purified pharmaceutical water and the like, and more particularly to a device for producing purified pharmaceutical water having a reverse osmosis membrane part for purifying treated water through a reverse osmosis membrane.

  For example, in order to produce a pharmaceutical product, it is decided to use purified water which is pharmaceutical water. This pharmaceutical purified water may be produced by purifying the water to be treated by a filtration means using a filtration membrane such as a reverse osmosis membrane. And the density | concentration of the impurity contained in to-be-processed water can be made smaller by setting it as the structure which permeate | transmits several filtration means.

  In Patent Document 1, an RO liquid feed pump is provided in a communication line directly connecting the first and second MF membrane modules and the RO membrane module, and a pressure sensor is provided on the suction side of the RO liquid pump. In addition, the primary side of the RO membrane module and the secondary side of the MF membrane module are connected to each other by a backwash line, and when the second MF membrane module is backwashed, the RO liquid feed pump uses the suction pressure. Discloses a filtration device that is driven and controlled to maintain a predetermined set pressure.

JP 2011-177653 A

However, when the filtration apparatus is a multistage configuration in which a plurality of filtration means are connected in series without being stored in an intermediate tank or the like on the way, it may be difficult to control when the treated water is permeated.
The object of the present invention is to make it easier to control when the water to be treated is permeated even when the filtration device is configured in a multistage configuration in which a plurality of filtration means are connected in series without being stored in the middle by an intermediate tank or the like. It is intended to provide a pharmaceutical purified water production apparatus and the like.

  Thus, according to the present invention, there is provided a pharmaceutical purified water production apparatus for purifying treated water to produce purified water that is pharmaceutical water, a free chlorine removing unit that removes free chlorine in the treated water, A filtration unit that filters the treated water, and the filtration unit includes a first filtration unit that purifies the treated water by permeating the filtration membrane, and a first permeated water that has passed through the first filtration unit. , A second filtering means for further purifying by permeating the filtration membrane without storing, a first sending means for sending the water to be treated to the first filtering means, and a second filtering means On the other hand, the second sending means for sending the first permeated water, the first sending means so that the pressure of the first permeated water is within a predetermined range, and the second sending means The flow rate of the second permeated water that has passed through the second filtering means is within a predetermined range. Pharmaceutical purified water manufacturing apparatus for a control means for, comprising: a is provided.

  Here, the first filtration means and the second filtration means can perform filtration using a reverse osmosis membrane.

  Furthermore, according to the present invention, a method for producing purified pharmaceutical water that purifies the treated water and produces purified water that is pharmaceutical water, the free chlorine removing step for removing free chlorine in the treated water; The first permeated water that has passed through the first filtering means is stored in the first filtering step that allows the treated water to permeate through the first filtering means that includes the filtering membrane, and the second filtering means that includes the filtering membrane. And the first filtration means for delivering the water to be treated to the first filtration means so that the pressure of the first permeate is within a predetermined range. Second permeated water that has passed through the second filtering means using the first sending step for sending the water to be treated and the second sending means for sending the first permeated water to the second filtering means. A second delivery step of delivering the first permeate so that the flow rate of the fluid is within a predetermined range; Process for the manufacture of a pharmaceutical purified water, characterized in Mukoto is provided.

  Furthermore, according to the present invention, a plurality of filtering means for allowing the water to be treated or permeate to permeate the filtration membrane without being stored in the middle, and a plurality of filtering means are provided in front of each of the plurality of filtering means. Water is sent to the filtering means other than the last-stage filtering means so that the pressure of the permeated water is within a predetermined range, and the flow rate of the permeated water is predetermined for the last-stage filtering means. And a plurality of delivery means for delivering water so as to be within the specified range.

  Furthermore, according to the present invention, the first filtration means for purifying the water to be treated through the filtration membrane, and the filtration membrane without storing the first permeated water that has passed through the first filtration means. The second filtration means for further purification by permeating, the first delivery means for delivering the water to be treated to the first filtration means, and the first permeate for the second filtration means The second delivery means for delivering the water and the first delivery means so that the pressure of the first permeated water is within a predetermined range and the second delivery means are passed through the second filtration means. And a control means for controlling the flow rate of the second permeated water to be within a predetermined range.

  According to the present invention, even when the filtration device has a multi-stage configuration in which a plurality of filtration means are connected in series without being stored in the middle by an intermediate tank or the like, control when permeating water to be treated becomes easier. A pharmaceutical purified water production apparatus or the like can be provided.

It is the figure explaining the pharmaceutical purified water manufacturing apparatus with which this Embodiment is applied. (A) is the figure which showed roughly about the RO unit of this Embodiment. (B) is the figure which showed the case where there are each three RO apparatuses and pumps of RO unit. (C) is the figure which showed the case where concentrated water is processed with another RO apparatus. It is the flowchart explaining operation | movement of the purified water manufacturing unit.

  Hereinafter, modes for carrying out the present invention (hereinafter, embodiments of the present invention) will be described in detail. The present invention is not limited to the following embodiments, and various modifications can be made within the scope of the invention. The drawings used are for explaining the present embodiment and do not represent the actual size.

  Hereinafter, a pharmaceutical purified water production apparatus to which the present embodiment is applied will be described with reference to the drawings.

FIG. 1 is a diagram illustrating a pharmaceutical purified water production apparatus to which the present embodiment is applied.
A purified water production unit 1 which is an example of the pharmaceutical purified water production apparatus shown in the figure is an apparatus for purifying treated water to produce pharmaceutical purified water.

  In the present embodiment, the water to be treated is, for example, normal water defined in each pharmaceutical article of the Japanese Pharmacopoeia. This regular water is required to meet water quality standards based on Article 4 of the Water Supply Law. More specifically, 50 items are defined by the Ministry of Health, Labor and Welfare Ordinance No. 101 as water quality standards. In addition to this standard, ammonium is required to meet the standard of “0.05 mg / L or less”.

As the normal water, for example, tap water or well water subjected to disinfection treatment is used. For this reason, normal water usually contains free chlorine resulting from the chlorinating agent used for disinfection. As the chlorine agent, for example, sodium hypochlorite (NaClO) is used. And as free chlorine resulting from this, hypochlorous acid (HOCl), hypochlorite ion (OCl < ^- >), etc. are mentioned.

  In the present embodiment, the pharmaceutical purified water is water for pharmaceutical use, and is purified water defined in each pharmaceutical article of the Japanese Pharmacopoeia. This purified water needs to satisfy the criteria that the organic carbon is 0.50 mg / L or less and the conductivity (25 ° C.) is 2.1 μS / cm or less. Purified water is used for the production of drug substances, solubilizers in pharmaceutical preparations, cleaning of pharmaceutical equipment, adjustment of reagent reagent solutions, cleaning of medical instruments, adjustment of preservatives for contact lenses.

  As shown in the figure, the purified water production unit 1 removes the raw water tank 20 that stores the treated water that is the raw water, the heating device 30 that adjusts the temperature of the treated water, and the free chlorine contained in the treated water. Activated carbon tower 40, prefilter 50 that removes solids from the water to be treated that has passed through activated carbon tower 40, RO (Reverse Osmosis Membrane) unit 60 that purifies the water to be treated, and after purification A storage tank 70 for storing purified pharmaceutical water and a control unit 80 for controlling the entire purified water production unit 1 are provided. The raw water tank 20, the heating device 30, the activated carbon tower 40, the prefilter 50, the RO unit 60, and the storage tank 70 are connected in series by pipes H2, H3, H4, H5, and H6 made of stainless steel or resin. Further, the storage tank 70 is provided with a loop pipe R that supplies pharmaceutical purified water from the storage tank 70 and returns to the storage tank 70 again through a use point. A pump P1 is provided in the middle of the pipe H2, and a pump P2 is provided in the loop pipe R.

  In this embodiment, tap water is used as the water to be treated. Therefore, it already has a predetermined water pressure, and the water to be treated enters the raw water tank 20 by using this water pressure.

  The raw water tank 20 temporarily stores treated water. And the to-be-processed water is sent to the apparatus of a back | latter stage from the raw | natural water tank 20 by driving the pump P1.

  The heating device 30 is a device including a heat exchanger, for example. Then, for example, by supplying steam to the heat exchanger, heat exchange is performed with the water to be treated to heat the water to be treated. The temperature of the water to be treated is, for example, 5 ° C. In the heating device 30, during normal operation, the water to be treated is heated to, for example, 25 ° C., and the performance of a reverse osmosis membrane (RO membrane), which will be described later, is improved.

  Further, by using the heating device 30, it is possible to sterilize the subsequent device and the piping. At this time, the heating device 30 heats the water to be treated to, for example, 85 ° C. and supplies it as hot water. Thereby, the latter apparatus and piping can be thermally sterilized. Note that free chlorine is not removed in the raw water tank 20 and remains in the water to be treated in the raw water tank 20, so that the raw water tank 20 need not be sterilized. On the other hand, as will be described in detail later, since the free chlorine is removed in the activated carbon tower 40, it is necessary to periodically sterilize the devices and pipes subsequent to the heating device 30.

  The activated carbon tower 40 is an example of a free chlorine removing unit, and is a device that fills activated carbon inside. And the free chlorine contained in to-be-processed water is removed by passing to-be-processed water through activated carbon. The activated carbon used in the activated carbon tower 40 is not particularly limited. For example, activated carbon is roughly classified into coal-based activated carbon and coconut shell activated carbon depending on the raw material for producing activated carbon, and any of them can be used. However, it is preferable that the activated carbon contains as few impurities as possible because it is less likely to elute.

  In addition, if it is an apparatus which has the function to remove the free chlorine contained in to-be-processed water, you may be other apparatuses instead of the activated carbon tower 40. For example, a device that uses sodium sulfite to reduce free chlorine in the water to be treated, or a device that decomposes free chlorine by irradiation with ultraviolet rays may be used.

  The prefilter 50 removes solids such as fine particles. In the case of the present embodiment, activated carbon particles may be generated in the activated carbon tower 40. The activated carbon fine particles may block the reverse osmosis membrane when passed through the subsequent RO unit 60 as it is, so the activated carbon fine particles are removed in advance by the prefilter 50.

The RO unit 60 is a device including a reverse osmosis membrane (RO membrane), and is an example of a filtration device and a filtration unit. The RO unit 60 purifies the water to be treated by filtering impurities contained in the water to be treated by the reverse osmosis membrane. In the present embodiment, the reverse osmosis membrane is an example of a filtration membrane.
A reverse osmosis membrane is a membrane in which a large number of pores having a size of about 1 nm to 2 nm are formed, and has a property of allowing water to permeate but not ion. Therefore, it is possible to remove impurities and salts from the water to be treated for purification. An example of the reverse osmosis membrane is a polyamide membrane.

  The storage tank 70 stores water that has passed through the RO unit 60 and has become purified pharmaceutical water. Then, the pharmaceutical purified water is sent from the storage tank 70 to each use point through the loop pipe R by driving the pump P2.

Next, the RO unit 60 will be described in further detail.
FIG. 2A is a diagram schematically showing the RO unit 60 of the present embodiment.
In the present embodiment, the RO unit 60 includes a plurality of RO apparatuses that are examples of a plurality of filtering means that allow the water to be treated or the permeated water to permeate through the filtration membrane without being stored in the middle. In this case, the filtration membrane corresponds to a reverse osmosis membrane (RO membrane). In the illustrated example, two RO devices, RO device 62 and RO device 64, are provided.

  The RO device 62 is an example of a first filtration means that purifies the water to be treated by permeating the filtration membrane. Then, the RO device 62 discharges the first permeated water that has passed through the reverse osmosis membrane and the first concentrated water that has not permeated the reverse osmosis membrane. The first permeated water is water that has been purified by removing impurities. The first concentrated water is water in which impurities are concentrated.

  The RO device 64 is an example of a second filtering unit that further purifies the first permeated water that has passed through the RO device 62 by allowing it to pass through the filtration membrane without storing it. From the RO apparatus 64, the 2nd permeated water which is the water after permeate | transmitting a reverse osmosis membrane and the 2nd concentrated water which did not permeate | transmit a reverse osmosis membrane are discharged | emitted. The second permeated water is purified water from which impurities are further removed. The second concentrated water is water in which impurities are concentrated.

  In addition, the RO unit 60 of the present embodiment is provided with a plurality of pumps that are examples of a plurality of delivery means provided at the front stage of each of the plurality of RO devices. In the illustrated example, two pumps of a pump 61 and a pump 63 are provided.

  The pump 61 is an example of a first delivery unit that delivers treated water to the RO device 62. The pump 63 is an example of a second delivery unit that delivers treated water to the RO device 64.

  Furthermore, in the present embodiment, the RO unit 60 includes a pressure sensor 62P that measures the pressure of the first permeated water that has passed through the RO device 62, and a flow rate sensor 64F that measures the flow rate of the second permeated water.

  In the present embodiment, the pump 61, the RO device 62, the pump 63, and the RO device 64 are connected in series. By setting the RO device to a multistage configuration (in this case, a two-stage configuration), the purity of the pharmaceutical purified water after purifying the water to be treated can be improved. Further, the water that has passed through the RO device 62 reaches the RO device 64 without being stored in an intermediate tank or the like. Thereby, the installation space of RO unit 60 and the manufacturing cost of equipment can be reduced.

  As shown in FIG. 2C, the concentrated water may be further processed by an RO membrane or another RO device. This is employed when two-stage concentration is performed in order to increase the recovery rate of water or to increase the concentration factor of valuable substances when the valuable water is contained in the concentrated water. However, this form is not called here that the RO device has a multi-stage configuration.

  Furthermore, in this embodiment, water is sent to a plurality of pumps so that the permeated water pressure is within a predetermined range with respect to the RO devices excluding the final stage RO device among the plurality of RO devices. Then, control is performed to send water to the final stage RO device so that the flow rate of the permeated water is within a predetermined range. That is, for the most downstream RO device among a plurality of RO devices, the pump immediately before this RO device is controlled so that the flow rate of the permeated water of this RO device is within a predetermined range. To do. For the RO devices other than the most downstream RO device, the pumps in the immediately preceding stage are controlled so that the pressure of the permeated water is within a predetermined range.

  More specifically, in the example of FIG. 2A, the control unit 80 controls the pump 61 so that the pressure of the first permeated water that has passed through the RO device 62 is within a predetermined range. The pump 63 is controlled so that the flow rate of the second permeated water that has passed through the RO device 64 falls within a predetermined range. In FIG. 2 (a), the control in which the pressure is within a predetermined range is illustrated as the outlet PIC control, and the control in which the flow rate is within the predetermined range is illustrated as the outlet FIC control.

  Actually, the pump 61 and the pump 63 are inverter-controlled, and this control is performed by the control unit 80. That is, the control unit 80 functions as a control unit.

  FIG. 2A shows the case where there are two RO devices and two pumps, but FIG. 2B shows the case where there are three RO devices. In this case, among the two pumps, excluding the final pump, among the pumps indicated by P, the control is performed such that the pressure of the permeated water of the RO device to which each pump delivers the treated water is within a predetermined range. I do. Further, for the third pump, which is the final stage pump, control is performed so that the flow rate of the permeated water of the final stage RO device to which the pump delivers the water to be treated is within a predetermined range. The same applies when there are four or more pumps or RO devices.

Conventionally, when the RO device has a multi-stage configuration, it is common to perform control so that the flow rate of the permeated water is within a predetermined range with respect to the pump that sends the water to be treated to each RO device. .
However, when such control is performed, problems described in the following (1) to (3) are likely to occur.

  (1) When the purified water production unit 1 is started, each device is started sequentially from the upstream side to the downstream side. At this time, the RO unit 60 first activates the pump 61 and sends treated water to the RO device 62, and then activates the pump 63 and sends treated water to the RO device 64. In this case, when the pump 61 is started, resistance is generated by the reverse osmosis membrane of the RO device 62. And since the pump 63 has not started yet, a bigger resistance arises. At this time, when the pump 61 is controlled so that the flow rate of the first permeated water falls within a predetermined range, control is performed so that the load on the pump 61 becomes larger. In this case, the pressure of the first permeate rapidly rises and the pressure sensor 62P detects an excessive pressure. As a result, the control unit 80 makes an emergency stop of the RO unit 60 in order to avoid pressure damage of the device. There is. In this case, when the pressure detected by the pressure sensor 62P exceeds a predetermined value, the control unit 80 performs control to urgently stop the apparatus.

  (2) Even when the emergency stop of (1) does not occur, when the pump 63 is started, the flow rate of the first permeate is controlled to be within a predetermined range with respect to the pump 61. In this case, the amount of the first permeate is insufficient. In this case, the pressure sensor 62P detects negative pressure, and the control unit 80 may urgently stop the RO unit 60 in order to avoid damage to the apparatus due to negative pressure cavitation. In this case, the control unit 80 performs an emergency stop control when the pressure detected by the pressure sensor 62P is less than a predetermined positive pressure.

  (3) Furthermore, the flow rate of the first concentrated water and the second concentrated water may change due to the secular change of the reverse osmosis membrane or the temperature change of the water to be treated. Therefore, even when this flow rate is adjusted to a predetermined flow rate, the above phenomena (1) to (2) may occur. Therefore, careful attention is required for the flow rate adjustment work, and operation management becomes more difficult.

The problems (1) to (3) are that the flow rate of the first permeated water that has passed through the RO device 62 through the pump 61 is preliminarily determined when the RO device has a multistage configuration without providing an intermediate tank or the like. This is a phenomenon that occurs because control is performed to be within a predetermined range.
Therefore, in the present embodiment, the pump 61 is controlled so that the pressure of the first permeated water that has passed through the RO device 62 falls within a predetermined range. In this case, in the case of (1) above, when the pressure of the first permeated water rises, the pump 61 performs control to reduce the water to be treated to be fed into the RO device 62, and the first The pressure of the permeated water is not excessive. Further, in the case of (2), in order to prevent the pressure of the first permeated water from decreasing, the pump 61 performs control to send more water to be treated to the RO device 62, so that the inlet of the pump 63 is The device can be kept operating at a positive pressure. Similarly, the problem (3) is less likely to occur.

Next, the operation of the purified water production unit 1 will be described.
FIG. 3 is a flowchart for explaining the operation of the purified water production unit 1.
Hereinafter, based on FIGS. 1-3, operation | movement of the purified water manufacturing unit 1 is demonstrated.

  First, the water to be treated is introduced into the raw water tank 20 and temporarily stored in the raw water tank 20 (step 101).

  Then, it is determined whether the activated carbon tower 40 or the like needs to be sterilized (step 102). The time of sterilization can be determined by the water flow time and the water flow amount. When it is necessary to sterilize (Yes in step 102), the water to be treated is supplied as hot water by the heating device 30 with the pump P1, and sterilized (step 103). After sterilization, the process returns to step 101.

On the other hand, when it is not necessary to sterilize (No in step 102), the temperature is heated to a certain temperature by the heating device 30 and sent to the activated carbon tower 40 (step 104).
And the free chlorine in to-be-processed water is removed with the activated carbon tower 40 in to-be-processed water (step 105: free chlorine removal process). Further, fine particles in the water to be treated are removed by the prefilter 50 (step 106).

Next, the RO unit 60 purifies the water to be treated.
At this time, the control unit 80 controls the pump 61 so that the pressure of the first permeated water that has passed through the RO device 62 falls within a predetermined range (step 107: first delivery step). Thus, the water to be treated passes through the RO device 62 and is filtered by the reverse osmosis membrane (step 108: first filtration step).
The control unit 80 controls the pump 63 so that the flow rate of the second permeated water that has passed through the RO device 64 is within a predetermined range (step 109: second delivery step). As a result, the water to be treated passes through the RO device 64 and is filtered by the reverse osmosis membrane (step 110: second filtration step).

  The water that has passed through the RO unit 60 is stored in the storage tank 70 as purified pharmaceutical water (step 111).

  The purified water production unit 1 described in detail above has described an example in which an RO device using a reverse osmosis membrane is used as a filtering means, but is not limited thereto, and is particularly limited as long as it has a filtering function. It is not a thing. For example, a UF (Ultrafiltration Membrane) device using an ultrafiltration membrane may be used.

Further, in the purified water production unit 1 described in detail above, the RO unit 60 is used as a device for purifying the water to be treated. For example, an EDI (Electrodeionization: Continuous Electric Regenerative Pure Water Device) unit is provided downstream of the RO unit 60. For example, other devices may be used in combination.
Further, a deaeration membrane, a safety filter, or the like may be provided between the filtering means such as the RO device of the RO unit 60.

  Further, in the above-described example, the control is performed to send water so that the flow rate of the permeated water is within a predetermined range for the final stage RO device, but this is not essential. In other words, if control is performed to send water so that the pressure of the permeate is within a predetermined range for other RO devices other than the final stage, the water flow is stabilized. Control may not be necessary.

  Furthermore, in the example mentioned above, although the RO unit 60 was used for manufacture of pharmaceutical purified water, it is not restricted to this. For example, it can be used for producing pure water or desalinating seawater.

  EXAMPLES Hereinafter, although this invention is demonstrated in detail using an Example, this invention is not limited by these Examples, unless the summary is exceeded.

Example 1
In this example, the purified water production unit 1 shown in FIGS. 1 and 2A was used.
Among these, NTR-759HR manufactured by Nitto Denko Corporation was used as the reverse osmosis membrane of the RO device 62 of the RO unit 60. This comprises a spiral 8 inch composite composite membrane. Then, 20 of these were used, and four FRP vessels were filled with four each. Of these, 3 vessels were configured as the 1st bank, and 2 vessels were configured as the 2st bank.
As the pump 61, an inverter-controlled pump was prepared. It has a capacity of 25.8 m ^{3 /} h × 130 mH × 18.5 kW.

Similarly, NTR-759HR manufactured by Nitto Denko Corporation was used as the reverse osmosis membrane of the RO device 64. Then, 16 of these were used, and 4 FRP vessels were filled with 4 each. Of these, 3 vessels were configured as the 1st bank, and 1 vessel was configured as the 2st bank.
As the pump 63, an inverter-controlled pump was prepared. It has a capacity of 16.6 m ³ / h × 137 mH × 11 kW.

  In addition, a deaeration membrane (X50 · 10 ″ × 28 ″) manufactured by Polypore Corporation was provided between the RO device 62 and the RO device 64.

Then, the control unit 80 controls the pump 61 so that the pressure of the first permeate is 0.25 MPa, and the pump 63 is controlled so that the flow rate of the second permeate is 13.9 m ³ / h. .

  As a result, the emergency stop or the like of the RO unit 60 did not occur even under various operating conditions. In other words, when the apparatus was started, when the flow rate of the first concentrated water and the second concentrated water was adjusted, when the temperature of the water to be treated changed, stable operation could be performed even after the reverse osmosis membrane was aged. . The power consumption of the pump 61 is about 81% of the rating, the power consumption of the pump 63 is about 77% of the rating, and the power consumption is smaller.

(Comparative Example 1)
Except that the pump 61 was controlled so that the flow rate of the first permeated water was 13.9 m ³ / h, and an intermediate tank was provided between the RO device 62 and the RO device 64, the same as in Example 1. The RO unit 60 was operated.
Providing an intermediate tank no longer causes an emergency stop when the device is started. However, the space for installing the intermediate tank and the installation cost were separately required. Also, since the intermediate tank is likely to propagate bacteria, it is necessary to use stainless steel, an immersion ultraviolet sterilizer inside, and a sterilization filter at the intermediate tank vent. Therefore, the installation cost of the intermediate tank further increased. Further, the pressure of the first permeated water discharged from the RO device 62 cannot be used due to the installation of the intermediate tank, so that the power consumption required for the pump 63 is increased and the power consumption is increased as compared with the first embodiment.

DESCRIPTION OF SYMBOLS 1 ... Purified water production unit, 20 ... Raw water tank, 30 ... Heating apparatus, 40 ... Activated carbon tower, 50 ... Pre filter, 60 ... RO unit, 61, 63 ... Pump, 62, 64 ... RO apparatus, 70 ... Storage tank 80 ... Control unit

Claims (5)

A device for producing purified pharmaceutical water that purifies treated water and produces purified water that is pharmaceutical water,
A free chlorine removing section for removing free chlorine in the water to be treated;
A filtration unit for filtering the water to be treated;
With
The filtration unit is
A first filtration means for performing purification by allowing the water to be treated to pass through the filtration membrane;
A second filtration means for further purification by allowing the first permeated water that has passed through the first filtration means to pass through the filtration membrane without storing;
First delivery means for delivering treated water to the first filtration means;
Second delivery means for delivering the first permeate to the second filtration means;
The pressure of the first permeate is made to be within a predetermined range for the first delivery means, and the second permeate that has passed through the second filtration means for the second delivery means. Control means for causing the flow rate to be within a predetermined range;
A device for producing purified pharmaceutical water, comprising:   The said 1st filtration means and the said 2nd filtration means filter using a reverse osmosis membrane, The pharmaceutical purified water manufacturing apparatus of Claim 1 characterized by the above-mentioned. A method for producing pharmaceutical purified water, comprising purifying treated water and producing purified water that is pharmaceutical water,
A free chlorine removal step for removing free chlorine in the water to be treated;
A first filtration step for allowing the water to be treated to pass through the first filtration means including a filtration membrane;
A second filtration step of allowing the second filtration means including the filtration membrane to pass through without storing the first permeated water that has passed through the first filtration means;
A first delivery means for delivering treated water to the first filtration means is used to deliver the treated water so that the pressure of the first permeate falls within a predetermined range. The delivery process of
Using the second sending means for sending the first permeated water to the second filtering means, the flow rate of the second permeated water that has passed through the second filtering means is within a predetermined range. A second delivery step for delivering the first permeated water,
A method for producing purified pharmaceutical water, comprising: A plurality of filtration means for allowing the water to be treated or permeate to permeate the filtration membrane without storing in the middle;
Water is provided so that the permeated water pressure is within a predetermined range for the filtering means provided in the front stage of each of the plurality of filtering means and excluding the last-stage filtering means among the plurality of filtering means. A plurality of delivery means for delivering water so that the flow rate of the permeated water is within a predetermined range for the filtration means at the final stage;
A filtration apparatus comprising: A first filtration means for performing purification by allowing the water to be treated to pass through the filtration membrane;
A second filtration means for further purification by allowing the first permeated water that has passed through the first filtration means to pass through the filtration membrane without storing;
First delivery means for delivering treated water to the first filtration means;
Second delivery means for delivering the first permeate to the second filtration means;
The pressure of the first permeate is made to be within a predetermined range for the first delivery means, and the second permeate that has passed through the second filtration means for the second delivery means. Control means for causing the flow rate to be within a predetermined range;
A filtration apparatus comprising:

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