JP2016169229A5 - - Google Patents

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Publication number
JP2016169229A5
JP2016169229A5 JP2016120503A JP2016120503A JP2016169229A5 JP 2016169229 A5 JP2016169229 A5 JP 2016169229A5 JP 2016120503 A JP2016120503 A JP 2016120503A JP 2016120503 A JP2016120503 A JP 2016120503A JP 2016169229 A5 JP2016169229 A5 JP 2016169229A5
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JP
Japan
Prior art keywords
pik3ca
subject
mutation
neratinib
composition
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Withdrawn
Application number
JP2016120503A
Other languages
English (en)
Japanese (ja)
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JP2016169229A (ja
Filing date
Publication date
Application filed filed Critical
Publication of JP2016169229A publication Critical patent/JP2016169229A/ja
Publication of JP2016169229A5 publication Critical patent/JP2016169229A5/ja
Withdrawn legal-status Critical Current

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JP2016120503A 2009-12-11 2016-06-17 ホスファチジルイノシトール−３−キナーゼ経路バイオマーカー Withdrawn JP2016169229A (ja)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
US28582109P 2009-12-11 2009-12-11
US61/285,821 2009-12-11
US28787209P 2009-12-18 2009-12-18
US61/287,872 2009-12-18

Related Parent Applications (1)

Application Number Title Priority Date Filing Date
JP2015051863A Division JP2015110669A (ja) 2009-12-11 2015-03-16 ホスファチジルイノシトール−３−キナーゼ経路バイオマーカー

Related Child Applications (1)

Application Number Title Priority Date Filing Date
JP2017038956A Division JP2017101072A (ja) 2009-12-11 2017-03-02 ホスファチジルイノシトール−３−キナーゼ経路バイオマーカー

Publications (2)

Publication Number Publication Date
JP2016169229A JP2016169229A (ja) 2016-09-23
JP2016169229A5 true JP2016169229A5 (OSRAM) 2017-04-06

Family

ID=43628745

Family Applications (7)

Application Number Title Priority Date Filing Date
JP2010273484A Withdrawn JP2011121944A (ja) 2009-12-11 2010-12-08 ホスファチジルイノシトール−３−キナーゼ経路バイオマーカー
JP2015051863A Pending JP2015110669A (ja) 2009-12-11 2015-03-16 ホスファチジルイノシトール−３−キナーゼ経路バイオマーカー
JP2016120503A Withdrawn JP2016169229A (ja) 2009-12-11 2016-06-17 ホスファチジルイノシトール−３−キナーゼ経路バイオマーカー
JP2017038956A Withdrawn JP2017101072A (ja) 2009-12-11 2017-03-02 ホスファチジルイノシトール−３−キナーゼ経路バイオマーカー
JP2018246698A Withdrawn JP2019052187A (ja) 2009-12-11 2018-12-28 ホスファチジルイノシトール−３−キナーゼ経路バイオマーカー
JP2020119091A Withdrawn JP2020169212A (ja) 2009-12-11 2020-07-10 ホスファチジルイノシトール−３−キナーゼ経路バイオマーカー
JP2021192872A Pending JP2022022296A (ja) 2009-12-11 2021-11-29 ホスファチジルイノシトール－３－キナーゼ経路バイオマーカー

Family Applications Before (2)

Application Number Title Priority Date Filing Date
JP2010273484A Withdrawn JP2011121944A (ja) 2009-12-11 2010-12-08 ホスファチジルイノシトール−３−キナーゼ経路バイオマーカー
JP2015051863A Pending JP2015110669A (ja) 2009-12-11 2015-03-16 ホスファチジルイノシトール−３−キナーゼ経路バイオマーカー

Family Applications After (4)

Application Number Title Priority Date Filing Date
JP2017038956A Withdrawn JP2017101072A (ja) 2009-12-11 2017-03-02 ホスファチジルイノシトール−３−キナーゼ経路バイオマーカー
JP2018246698A Withdrawn JP2019052187A (ja) 2009-12-11 2018-12-28 ホスファチジルイノシトール−３−キナーゼ経路バイオマーカー
JP2020119091A Withdrawn JP2020169212A (ja) 2009-12-11 2020-07-10 ホスファチジルイノシトール−３−キナーゼ経路バイオマーカー
JP2021192872A Pending JP2022022296A (ja) 2009-12-11 2021-11-29 ホスファチジルイノシトール－３－キナーゼ経路バイオマーカー

Country Status (5)

Country Link
US (4) US20130189274A1 (OSRAM)
EP (2) EP3575413A1 (OSRAM)
JP (7) JP2011121944A (OSRAM)
CA (1) CA2783743C (OSRAM)
WO (1) WO2011070499A1 (OSRAM)

Families Citing this family (19)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DK1848414T3 (da) 2005-02-03 2011-07-25 Gen Hospital Corp Fremgangsmåde til behandling af gefitinib-resistent cancer
AU2006311877A1 (en) 2005-11-04 2007-05-18 Wyeth Llc Antineoplastic combinations with mTOR inhibitor, herceptin, and/orHKI-272
US8022216B2 (en) 2007-10-17 2011-09-20 Wyeth Llc Maleate salts of (E)-N-{4-[3-chloro-4-(2-pyridinylmethoxy)anilino]-3-cyano-7-ethoxy-6-quinolinyl}-4-(dimethylamino)-2-butenamide and crystalline forms thereof
SI2310011T1 (sl) 2008-06-17 2013-10-30 Wyeth Llc Antineoplastične kombinacije, ki vsebujejo HKI-272 in vinorelbin
BRPI0916694B1 (pt) 2008-08-04 2021-06-08 Wyeth Llc uso de neratinibe em combinação com capecitabina para tratar câncer de mama metastático de erbb-2 positivo, kit e produto compreendendo os mesmos
CA2755789C (en) 2009-04-06 2016-01-19 Wyeth Llc Treatment regimen utilizing neratinib for breast cancer
CN107441058A (zh) 2009-11-09 2017-12-08 惠氏有限责任公司 包衣药物球状体及消除或减少病症如呕吐和腹泻的用途
CA2843222A1 (en) * 2011-07-28 2013-01-31 Genentech, Inc. Pik3ca h1047r knock-in non-human animal breast cancer model
WO2013083810A1 (en) * 2011-12-09 2013-06-13 F. Hoffmann-La Roche Ag Identification of non-responders to her2 inhibitors
SG10201706196XA (en) * 2012-06-08 2017-08-30 Hoffmann La Roche Mutant selectivity and combinations of a phosphoinositide 3 kinase inhibitor compound and chemotherapeutic agents for the treatment of cancer
CN105274188A (zh) * 2014-05-29 2016-01-27 北京雅康博生物科技有限公司 Pik3ca基因突变检测试剂盒
CA2985894A1 (en) * 2015-05-15 2016-11-24 Memorial Sloan-Kettering Cancer Center Use of phosphoinositide 3-kinase inhibitors for treatment of vascular malformations
US9607375B2 (en) * 2015-06-03 2017-03-28 Eileen B. Gallagher Biological data annotation and visualization
US10672505B2 (en) 2015-06-03 2020-06-02 General Electric Company Biological data annotation and visualization
US9953133B2 (en) 2015-06-03 2018-04-24 General Electric Company Biological data annotation and visualization
KR20190054826A (ko) * 2017-11-14 2019-05-22 한미약품 주식회사 암의 포지오티닙 치료에 대한 반응을 나타내는 바이오마커 및 그의 용도
EP3849538A4 (en) * 2018-09-10 2022-06-29 Mirati Therapeutics, Inc. Combination therapies
IT201800010730A1 (it) * 2018-11-30 2020-05-30 Univ Degli Studi Milano Metodo per classificare pazienti affetti da tumore alla mammella idonei per immunoterapia
MX2021009142A (es) 2019-02-06 2021-10-13 Venthera Inc Inhibidores topicos de fosfoinositol 3-cinasas.

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US7399865B2 (en) 2003-09-15 2008-07-15 Wyeth Protein tyrosine kinase enzyme inhibitors
US8105768B2 (en) * 2005-03-09 2012-01-31 Abbott Laboratories Methods of identifying patients for treatment with HER-2/neu inhibitors based on detection of HER-2/neu and TOP2A gene copy number
EP1899463A4 (en) * 2005-05-09 2009-11-25 Ariad Pharma Inc BIOMARKERS FOR EVALUATING THE PROBABILITY THAT A TUMOR IS SENSITIVE TO A MTOR INHIBITOR
AU2006311877A1 (en) 2005-11-04 2007-05-18 Wyeth Llc Antineoplastic combinations with mTOR inhibitor, herceptin, and/orHKI-272
EP1978106A1 (en) * 2007-04-07 2008-10-08 Universitätsklinikum Hamburg-Eppendorf Detection of ESR1 amplification in endometrium cancer and ovary cancer
US8715665B2 (en) * 2007-04-13 2014-05-06 The General Hospital Corporation Methods for treating cancer resistant to ErbB therapeutics
US8022216B2 (en) 2007-10-17 2011-09-20 Wyeth Llc Maleate salts of (E)-N-{4-[3-chloro-4-(2-pyridinylmethoxy)anilino]-3-cyano-7-ethoxy-6-quinolinyl}-4-(dimethylamino)-2-butenamide and crystalline forms thereof

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