JP2016056119A5 - - Google Patents
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- Publication number
- JP2016056119A5 JP2016056119A5 JP2014183058A JP2014183058A JP2016056119A5 JP 2016056119 A5 JP2016056119 A5 JP 2016056119A5 JP 2014183058 A JP2014183058 A JP 2014183058A JP 2014183058 A JP2014183058 A JP 2014183058A JP 2016056119 A5 JP2016056119 A5 JP 2016056119A5
- Authority
- JP
- Japan
- Prior art keywords
- fraction
- exosome
- rna
- milk
- active ingredient
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
- 210000001808 Exosomes Anatomy 0.000 claims 7
- 229920000160 (ribonucleotides)n+m Polymers 0.000 claims 3
- 210000004080 Milk Anatomy 0.000 claims 3
- 239000004480 active ingredient Substances 0.000 claims 3
- 235000013336 milk Nutrition 0.000 claims 3
- 239000008267 milk Substances 0.000 claims 3
- 239000005862 Whey Substances 0.000 claims 2
- 239000000158 apoptosis inhibitor Substances 0.000 claims 2
- 206010059512 Apoptosis Diseases 0.000 claims 1
- 230000006907 apoptotic process Effects 0.000 claims 1
- 235000013361 beverage Nutrition 0.000 claims 1
- 239000005018 casein Substances 0.000 claims 1
- 235000021240 caseins Nutrition 0.000 claims 1
- 210000004027 cells Anatomy 0.000 claims 1
- 235000013305 food Nutrition 0.000 claims 1
- 230000002401 inhibitory effect Effects 0.000 claims 1
- 150000002632 lipids Chemical class 0.000 claims 1
- 238000004519 manufacturing process Methods 0.000 claims 1
- 239000000203 mixture Substances 0.000 claims 1
Claims (3)
- 乳由来のエクソソーム、または、少なくともＲＮＡを含む該エクソソームの分画物を有効成分として含有する、アポトーシス抑制剤。
- アポトーシス抑制剤の製造方法であって、
乳から脂質画分、細胞画分及びカゼイン画分を除去してホエイ画分を調製する工程、
前記ホエイ画分からエクソソーム画分を回収する工程、及び、
前記エクソソーム画分、または、少なくともＲＮＡを含む該エクソソームの分画物を有効成分として製剤化する工程、
を含む方法。 - 乳由来のエクソソーム、または、少なくともＲＮＡを含む該エクソソームの分画物を有効成分として含有する、アポトーシス抑制用飲食品組成物。
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP2014183058A JP6469394B2 (ja) | 2014-09-09 | 2014-09-09 | アポトーシス抑制剤 |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP2014183058A JP6469394B2 (ja) | 2014-09-09 | 2014-09-09 | アポトーシス抑制剤 |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2016056119A JP2016056119A (ja) | 2016-04-21 |
| JP2016056119A5 true JP2016056119A5 (ja) | 2017-08-10 |
| JP6469394B2 JP6469394B2 (ja) | 2019-02-13 |
Family
ID=55757469
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2014183058A Active JP6469394B2 (ja) | 2014-09-09 | 2014-09-09 | アポトーシス抑制剤 |
Country Status (1)
| Country | Link |
|---|---|
| JP (1) | JP6469394B2 (ja) |
Families Citing this family (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| KR102109950B1 (ko) * | 2017-06-02 | 2020-05-12 | (주)엑솔런스바이오테크놀로지 | 체외충격파를 이용한 세포외소포체 내로의 표적물질 전달방법 |
| WO2020010161A1 (en) * | 2018-07-02 | 2020-01-09 | Pure Tech Health Llc | Milk vesicles for use in delivering biological agents |
| KR102223138B1 (ko) * | 2019-06-13 | 2021-03-04 | 충북대학교 산학협력단 | 우유로부터 유래된 엑소좀을 유효성분으로 포함하는 대사성 질환 치료용 약학적 조성물 |
| JP7162693B1 (ja) | 2021-04-19 | 2022-10-28 | ボルド エルドン | 馬乳酒由来エクソソーム及びその使用 |
-
2014
- 2014-09-09 JP JP2014183058A patent/JP6469394B2/ja active Active
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