JP2015536322A - 肺又は他の臓器の体外細胞療法用装置 - Google Patents

肺又は他の臓器の体外細胞療法用装置 Download PDF

Info

Publication number
JP2015536322A
JP2015536322A JP2015537771A JP2015537771A JP2015536322A JP 2015536322 A JP2015536322 A JP 2015536322A JP 2015537771 A JP2015537771 A JP 2015537771A JP 2015537771 A JP2015537771 A JP 2015537771A JP 2015536322 A JP2015536322 A JP 2015536322A
Authority
JP
Japan
Prior art keywords
organ
cells
resident
cell
delivering
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
JP2015537771A
Other languages
English (en)
Japanese (ja)
Other versions
JP2015536322A5 (enExample
Inventor
フリングス ピッテンゲル マーク
フリングス ピッテンゲル マーク
ゲラルド サンチェズ パブロ
ゲラルド サンチェズ パブロ
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Individual
Original Assignee
Individual
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Individual filed Critical Individual
Publication of JP2015536322A publication Critical patent/JP2015536322A/ja
Publication of JP2015536322A5 publication Critical patent/JP2015536322A5/ja
Pending legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
    • A01N1/00—Preservation of bodies of humans or animals, or parts thereof
    • A01N1/10—Preservation of living parts
    • A01N1/14—Mechanical aspects of preservation; Apparatus or containers therefor
    • A01N1/142—Apparatus
    • A01N1/143—Apparatus for organ perfusion
    • A—HUMAN NECESSITIES
    • A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
    • A01N1/00—Preservation of bodies of humans or animals, or parts thereof
    • A01N1/10—Preservation of living parts
    • A01N1/12—Chemical aspects of preservation
    • A01N1/122—Preservation or perfusion media
    • A01N1/126—Physiologically active agents, e.g. antioxidants or nutrients
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
    • A61K35/12—Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells
    • A61K35/28—Bone marrow; Haematopoietic stem cells; Mesenchymal stem cells of any origin, e.g. adipose-derived stem cells
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/18—Growth factors; Growth regulators
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/18—Growth factors; Growth regulators
    • A61K38/1833—Hepatocyte growth factor; Scatter factor; Tumor cytotoxic factor II
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/18—Growth factors; Growth regulators
    • A61K38/1891—Angiogenesic factors; Angiogenin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/19—Cytokines; Lymphokines; Interferons
    • A61K38/193—Colony stimulating factors [CSF]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/19—Cytokines; Lymphokines; Interferons
    • A61K38/196—Thrombopoietin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/19—Cytokines; Lymphokines; Interferons
    • A61K38/20—Interleukins [IL]
    • A61K38/2066—IL-10
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Zoology (AREA)
  • Immunology (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical & Material Sciences (AREA)
  • Public Health (AREA)
  • Epidemiology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Cell Biology (AREA)
  • Developmental Biology & Embryology (AREA)
  • Environmental Sciences (AREA)
  • Wood Science & Technology (AREA)
  • Dentistry (AREA)
  • Biotechnology (AREA)
  • Virology (AREA)
  • Hematology (AREA)
  • Biomedical Technology (AREA)
  • Vascular Medicine (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pulmonology (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Biophysics (AREA)
  • Physiology (AREA)
  • External Artificial Organs (AREA)
JP2015537771A 2012-10-15 2013-10-15 肺又は他の臓器の体外細胞療法用装置 Pending JP2015536322A (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201261713832P 2012-10-15 2012-10-15
US61/713,832 2012-10-15
PCT/US2013/065033 WO2014062669A1 (en) 2012-10-15 2013-10-15 Apparatus for extracorporeal cellular therapy of lung or other organ

Publications (2)

Publication Number Publication Date
JP2015536322A true JP2015536322A (ja) 2015-12-21
JP2015536322A5 JP2015536322A5 (enExample) 2016-12-01

Family

ID=50488692

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2015537771A Pending JP2015536322A (ja) 2012-10-15 2013-10-15 肺又は他の臓器の体外細胞療法用装置

Country Status (5)

Country Link
US (1) US20150296770A1 (enExample)
EP (1) EP2906232A4 (enExample)
JP (1) JP2015536322A (enExample)
AU (1) AU2013331412A1 (enExample)
WO (1) WO2014062669A1 (enExample)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2020033333A (ja) * 2018-08-16 2020-03-05 チャ ユニバーシティ インダストリー−アカデミック コオペレーション ファンデーション 脳卒中治療用組成物、及びそれをスクリーニングする方法

Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2835629B2 (ja) * 1989-05-18 1998-12-14 ザ リージェンツ オブ ザ ユニヴァーシティ オブ ミネソタ バイオリアクター装置
JP2003503022A (ja) * 1999-06-21 2003-01-28 ザ・ジェネラル・ホスピタル・コーポレイション 臓器補助装置のための細胞培養システムおよび方法
WO2010091188A1 (en) * 2009-02-04 2010-08-12 Yale University Tissue engineering of lung

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
BRPI0510271A (pt) * 2004-06-15 2007-10-30 Baxter Int aplicações ex-vivo agentes terapêuticos microparticulados
WO2011142670A1 (en) * 2010-05-12 2011-11-17 Xpand Biotechnology B.V. Cell-culture-bag
US9534204B2 (en) * 2010-10-05 2017-01-03 Aal Scientifics, Inc. Human lung stem cells and uses thereof
JP2013544524A (ja) * 2010-12-06 2013-12-19 ターポン バイオシステムズ，インコーポレイテッド 生物学的生成物の連続プロセス法
EP2714892B1 (en) * 2011-06-02 2018-02-21 President and Fellows of Harvard College Methods and uses for ex vivo tissue culture systems

Patent Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2835629B2 (ja) * 1989-05-18 1998-12-14 ザ リージェンツ オブ ザ ユニヴァーシティ オブ ミネソタ バイオリアクター装置
JP2003503022A (ja) * 1999-06-21 2003-01-28 ザ・ジェネラル・ホスピタル・コーポレイション 臓器補助装置のための細胞培養システムおよび方法
WO2010091188A1 (en) * 2009-02-04 2010-08-12 Yale University Tissue engineering of lung

Non-Patent Citations (3)

* Cited by examiner, † Cited by third party
Title
CYTOTECHNOLOGY, vol. Vol.44,No.No.1/2, JPN6017027019, 2004, pages 1 - 14, ISSN: 0003901439 *
PNAS, vol. 106, no. 38, JPN6017027023, 2009, pages 16357 - 16362, ISSN: 0003901440 *
STEM CELLS AND DEVELOPMENT, vol. 22, no. 2, JPN6017027025, 5 July 2012 (2012-07-05), pages 268 - 278, ISSN: 0003901441 *

Cited By (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2020033333A (ja) * 2018-08-16 2020-03-05 チャ ユニバーシティ インダストリー−アカデミック コオペレーション ファンデーション 脳卒中治療用組成物、及びそれをスクリーニングする方法
JP2021181469A (ja) * 2018-08-16 2021-11-25 チャ ユニバーシティ インダストリー−アカデミック コオペレーション ファンデーション 脳卒中治療用組成物、及びそれをスクリーニングする方法
JP2024073552A (ja) * 2018-08-16 2024-05-29 チャ ユニバーシティ インダストリー－アカデミック コオペレーション ファンデーション 脳卒中治療用組成物、及びそれをスクリーニングする方法

Also Published As

Publication number Publication date
AU2013331412A1 (en) 2015-06-04
WO2014062669A1 (en) 2014-04-24
EP2906232A4 (en) 2016-09-28
US20150296770A1 (en) 2015-10-22
EP2906232A1 (en) 2015-08-19

Similar Documents

Publication Publication Date Title
MOSS et al. Cerebral etiology of the “shock lung syndrome”
US11291202B2 (en) Administration and monitoring of nitric oxide in ex vivo fluids
Emaminia et al. Adenosine A2A agonist improves lung function during ex vivo lung perfusion
López-Martínez et al. Normothermic machine perfusion systems: where do we go from here?
US12052987B2 (en) Administration and monitoring of nitric oxide in ex vivo fluids
CN101466360A (zh) 用于细胞移植的多膜免疫隔离系统
US11950590B2 (en) Methods to improve organ viability
US12048303B2 (en) Systems and methods to perfuse isolated tissue
JP2018011979A (ja) 一酸化窒素を動脈血または動脈血化血（ａｒｔｅｒｉａｌｉｚｅｄ ｂｌｏｏｄ）に投与する方法
Bellomo et al. Normothermic extracorporeal perfusion of isolated porcine liver after warm ischaemia: a preliminary report
WO2021183774A1 (en) Treating acute respiratory distress
JP2015536322A (ja) 肺又は他の臓器の体外細胞療法用装置
Duignan et al. A multi-mode system for myocardial functional and physiological assessment during ex situ heart perfusion
Tomizawa et al. The effects of a neutrophil elastase inhibitor (ONO-5046· Na) and neutrophil depletion using a granulotrap (G-1) column on lung reperfusion injury in dogs
Andrijevic et al. Mechanisms and strategies for organ recovery
Forgie et al. Moderate-Flow Perfusion is Superior to Low-Flow Perfusion in Ex Situ Lung Perfusion
Kayumov et al. A Comparative Study Between Cold Static Storage and Normothermic Ex-Situ Donor Heart Preservation in a Rat Model of Heterotopic Heart Transplantation
Tracy et al. Lung rehabilitation using xenogeneic cross-circulation does not lead to hyperacute rejection in a human lung transplantation model
Varnavas et al. Chronic skeletal muscle ischemia preserves coronary flow in the ischemic rat heart
Malchesky Artificial organs 2014: a year in review
Brant et al. Successful transplantation in canines after long-term coronary sinus machine perfusion preservation of donor hearts
Boffini et al. Orthostatic Ex-Vivo Lung Perfusion (EVLP): A Proof of Concept
Rostron et al. Donor management
Van Raemdonck et al. Ex vivo management of lungs
Dashkevich et al. PDGF-B Is Protective During Ischemia-Reperfusion Injury in Rat Cardiac Allografts

Legal Events

Date Code Title Description
A521 Request for written amendment filed

Free format text: JAPANESE INTERMEDIATE CODE: A523

Effective date: 20161012

A621 Written request for application examination

Free format text: JAPANESE INTERMEDIATE CODE: A621

Effective date: 20161012

A521 Request for written amendment filed

Free format text: JAPANESE INTERMEDIATE CODE: A523

Effective date: 20161219

A131 Notification of reasons for refusal

Free format text: JAPANESE INTERMEDIATE CODE: A131

Effective date: 20170725

A601 Written request for extension of time

Free format text: JAPANESE INTERMEDIATE CODE: A601

Effective date: 20171016

A02 Decision of refusal

Free format text: JAPANESE INTERMEDIATE CODE: A02

Effective date: 20181023