JP2015534990A5 - - Google Patents

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Publication number
JP2015534990A5
JP2015534990A5 JP2015538124A JP2015538124A JP2015534990A5 JP 2015534990 A5 JP2015534990 A5 JP 2015534990A5 JP 2015538124 A JP2015538124 A JP 2015538124A JP 2015538124 A JP2015538124 A JP 2015538124A JP 2015534990 A5 JP2015534990 A5 JP 2015534990A5
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JP
Japan
Prior art keywords
aryl
group
alkyl
amino
compound
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
JP2015538124A
Other languages
English (en)
Japanese (ja)
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JP2015534990A (ja
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Publication date
Application filed filed Critical
Priority claimed from PCT/US2013/066041 external-priority patent/WO2014066304A1/en
Publication of JP2015534990A publication Critical patent/JP2015534990A/ja
Publication of JP2015534990A5 publication Critical patent/JP2015534990A5/ja
Pending legal-status Critical Current

Links

JP2015538124A 2012-10-22 2013-10-22 誤制御されたｅＩＦ４Ｅに関連する疾患又は障害を治療又は予防するための組成物及び方法 Pending JP2015534990A (ja)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
US201261716987P 2012-10-22 2012-10-22
US61/716,987 2012-10-22
US201261735458P 2012-12-10 2012-12-10
US61/735,458 2012-12-10
PCT/US2013/066041 WO2014066304A1 (en) 2012-10-22 2013-10-22 Compositions and methods for treating or preventing diseases or disorders associated with misregulated eif4e

Publications (2)

Publication Number Publication Date
JP2015534990A JP2015534990A (ja) 2015-12-07
JP2015534990A5 true JP2015534990A5 (https=) 2016-12-08

Family

ID=50545165

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2015538124A Pending JP2015534990A (ja) 2012-10-22 2013-10-22 誤制御されたｅＩＦ４Ｅに関連する疾患又は障害を治療又は予防するための組成物及び方法

Country Status (7)

Country Link
US (1) US9409901B2 (https=)
EP (1) EP2909203A4 (https=)
JP (1) JP2015534990A (https=)
AU (1) AU2013334860B2 (https=)
CA (1) CA2888889A1 (https=)
IL (1) IL238415B (https=)
WO (1) WO2014066304A1 (https=)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
MX2017015456A (es) * 2015-06-01 2018-11-29 Bantam Pharmaceutical Llc Compuestos de pirazol y pirrol sustituidos y metodos para su uso por inhibición de iniciación de traducción y tratamiento de enfermedades y trastornos relacionados con ellos.
US12150934B2 (en) 2016-11-30 2024-11-26 Bantam Pharmaceutical, Llc Methods of using substituted pyrazole and pyrazole compounds and for treatment of hyperproliferative diseases
CA3081983A1 (en) * 2016-11-30 2018-06-07 Bantam Pharmaceutical, Llc Substituted pyrazole compounds and methods of using them for treatment of hyperproliferative diseases
WO2021045538A1 (ko) * 2019-09-03 2021-03-11 소바젠 주식회사 eIF4E 저해제를 포함하는 eIF4E 활성증가와 관련된 상태의 진단 또는 치료용 조성물
WO2021067752A1 (en) * 2019-10-04 2021-04-08 Yale University Targeting cap-dependent translation to reduce seizures in mtor disorders
TW202146393A (zh) * 2020-03-03 2021-12-16 美商皮克醫療公司 Eif4e抑制劑及其用途

Family Cites Families (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5324718A (en) 1992-07-14 1994-06-28 Thorsteinn Loftsson Cyclodextrin/drug complexation
US5472954A (en) 1992-07-14 1995-12-05 Cyclops H.F. Cyclodextrin complexation
AU2005236055B2 (en) * 2004-04-20 2011-10-06 Transtech Pharma, Llc Substituted thiazole and pyrimidine derivatives as melanocortin receptor modulators
CA2619153C (en) * 2005-01-21 2013-12-31 President And Fellows Of Harvard College Regulation of protein synthesis by inhibition of eif4e-eif4g interaction
GB0614070D0 (en) * 2006-07-14 2006-08-23 Glaxo Group Ltd Compounds
GB0614068D0 (en) * 2006-07-14 2006-08-23 Glaxo Group Ltd Compounds
EP2078004B1 (en) 2006-10-31 2015-02-25 Merck Sharp & Dohme Corp. 2-aminothiazole-4-carboxylic amides as protein kinase inhibitors
US20100249030A1 (en) * 2007-07-31 2010-09-30 Schering Corporation Anti-mitotic agent and aurora kinase inhibitor combination as anti-cancer treatment
CA2803880C (en) * 2010-06-28 2018-09-25 President And Fellows Of Harvard College Compounds for the inhibition of cellular proliferation

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