JP2015534990A5 - - Google Patents

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Publication number
JP2015534990A5
JP2015534990A5 JP2015538124A JP2015538124A JP2015534990A5 JP 2015534990 A5 JP2015534990 A5 JP 2015534990A5 JP 2015538124 A JP2015538124 A JP 2015538124A JP 2015538124 A JP2015538124 A JP 2015538124A JP 2015534990 A5 JP2015534990 A5 JP 2015534990A5
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JP
Japan
Prior art keywords
aryl
group
alkyl
amino
compound
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
JP2015538124A
Other languages
English (en)
Japanese (ja)
Other versions
JP2015534990A (ja
Filing date
Publication date
Application filed filed Critical
Priority claimed from PCT/US2013/066041 external-priority patent/WO2014066304A1/en
Publication of JP2015534990A publication Critical patent/JP2015534990A/ja
Publication of JP2015534990A5 publication Critical patent/JP2015534990A5/ja
Pending legal-status Critical Current

Links

JP2015538124A 2012-10-22 2013-10-22 誤制御されたｅＩＦ４Ｅに関連する疾患又は障害を治療又は予防するための組成物及び方法 Pending JP2015534990A (ja)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
US201261716987P 2012-10-22 2012-10-22
US61/716,987 2012-10-22
US201261735458P 2012-12-10 2012-12-10
US61/735,458 2012-12-10
PCT/US2013/066041 WO2014066304A1 (en) 2012-10-22 2013-10-22 Compositions and methods for treating or preventing diseases or disorders associated with misregulated eif4e

Publications (2)

Publication Number Publication Date
JP2015534990A JP2015534990A (ja) 2015-12-07
JP2015534990A5 true JP2015534990A5 (enExample) 2016-12-08

Family

ID=50545165

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2015538124A Pending JP2015534990A (ja) 2012-10-22 2013-10-22 誤制御されたｅＩＦ４Ｅに関連する疾患又は障害を治療又は予防するための組成物及び方法

Country Status (7)

Country Link
US (1) US9409901B2 (enExample)
EP (1) EP2909203A4 (enExample)
JP (1) JP2015534990A (enExample)
AU (1) AU2013334860B2 (enExample)
CA (1) CA2888889A1 (enExample)
IL (1) IL238415B (enExample)
WO (1) WO2014066304A1 (enExample)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP6707630B2 (ja) * 2015-06-01 2020-06-10 バンタム、ファーマシューティカル、リミテッド、ライアビリティー、カンパニーＢａｎｔａｍ Ｐｈａｒｍａｃｅｕｔｉｃａｌ， Ｌｌｃ 置換ピラゾールおよびピロール化合物、および翻訳開始の阻害およびこれらに関連する疾患および障害の治療のためにこれらを用いる方法
MX2019006299A (es) * 2016-11-30 2019-11-12 Bantam Pharmaceutical Llc Compuestos de pirazola sustituida y metodos para usarlos para el tratamiento de enfermedades hiperproliferativas.
JP2020513403A (ja) 2016-11-30 2020-05-14 バンタム、ファーマシューティカル、リミテッド、ライアビリティー、カンパニーＢａｎｔａｍ Ｐｈａｒｍａｃｅｕｔｉｃａｌ， Ｌｌｃ 置換ピラゾールおよびピロール化合物の使用する方法ならびに過剰増殖性疾患の治療のための方法
AU2020343106B2 (en) * 2019-09-03 2025-04-10 Sovargen Co., Ltd. Composition for diagnosing or treating conditions associated with increased eIF4E activity comprising eIF4E inhibitor
WO2021067752A1 (en) * 2019-10-04 2021-04-08 Yale University Targeting cap-dependent translation to reduce seizures in mtor disorders
AR121506A1 (es) * 2020-03-03 2022-06-08 Pic Therapeutics Inc Inhibidores del eif4e y sus usos

Family Cites Families (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5472954A (en) 1992-07-14 1995-12-05 Cyclops H.F. Cyclodextrin complexation
US5324718A (en) 1992-07-14 1994-06-28 Thorsteinn Loftsson Cyclodextrin/drug complexation
NZ550114A (en) * 2004-04-20 2011-02-25 Transtech Pharma Inc Substituted thiazole and pyrimidine derivatives as melanocortin receptor modulators
EP1868604B1 (en) * 2005-01-21 2014-08-13 President and Fellows of Harvard College Regulation of protein synthesis by inhibition of eif4e-eif4g interaction
GB0614068D0 (en) * 2006-07-14 2006-08-23 Glaxo Group Ltd Compounds
GB0614070D0 (en) * 2006-07-14 2006-08-23 Glaxo Group Ltd Compounds
KR20090082440A (ko) * 2006-10-31 2009-07-30 쉐링 코포레이션 단백질 키나제 억제제로서의 2-아미노티아졸-4-카복실산 아미드
KR20100042287A (ko) * 2007-07-31 2010-04-23 쉐링 코포레이션 항암요법으로서의 항-유사분열제 및 아우로라 키나제 억제제 조합물
CA2803880C (en) 2010-06-28 2018-09-25 President And Fellows Of Harvard College Compounds for the inhibition of cellular proliferation

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