JP2015529457A5 - - Google Patents
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- JP2015529457A5 JP2015529457A5 JP2015525519A JP2015525519A JP2015529457A5 JP 2015529457 A5 JP2015529457 A5 JP 2015529457A5 JP 2015525519 A JP2015525519 A JP 2015525519A JP 2015525519 A JP2015525519 A JP 2015525519A JP 2015529457 A5 JP2015529457 A5 JP 2015529457A5
- Authority
- JP
- Japan
- Prior art keywords
- genetically modified
- hla
- cell
- nucleic acid
- acid sequence
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
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Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201261677739P | 2012-07-31 | 2012-07-31 | |
| US61/677,739 | 2012-07-31 | ||
| PCT/US2013/052767 WO2014022423A2 (en) | 2012-07-31 | 2013-07-30 | Hla g-modified cells and methods |
Related Child Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2018028816A Division JP6502544B2 (ja) | 2012-07-31 | 2018-02-21 | Ｈｌａ ｇ改変された細胞および方法 |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2015529457A JP2015529457A (ja) | 2015-10-08 |
| JP2015529457A5 true JP2015529457A5 (enExample) | 2016-09-15 |
| JP6297559B2 JP6297559B2 (ja) | 2018-03-20 |
Family
ID=50028654
Family Applications (4)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2015525519A Active JP6297559B2 (ja) | 2012-07-31 | 2013-07-30 | Ｈｌａｇ改変された細胞および方法 |
| JP2018028816A Active JP6502544B2 (ja) | 2012-07-31 | 2018-02-21 | Ｈｌａ ｇ改変された細胞および方法 |
| JP2019052699A Active JP7294838B2 (ja) | 2012-07-31 | 2019-03-20 | Ｈｌａ ｇ改変された細胞および方法 |
| JP2021068195A Active JP7379410B2 (ja) | 2012-07-31 | 2021-04-14 | Ｈｌａ ｇ改変された細胞および方法 |
Family Applications After (3)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2018028816A Active JP6502544B2 (ja) | 2012-07-31 | 2018-02-21 | Ｈｌａ ｇ改変された細胞および方法 |
| JP2019052699A Active JP7294838B2 (ja) | 2012-07-31 | 2019-03-20 | Ｈｌａ ｇ改変された細胞および方法 |
| JP2021068195A Active JP7379410B2 (ja) | 2012-07-31 | 2021-04-14 | Ｈｌａ ｇ改変された細胞および方法 |
Country Status (10)
| Country | Link |
|---|---|
| US (4) | US9714280B2 (enExample) |
| EP (4) | EP3805261A1 (enExample) |
| JP (4) | JP6297559B2 (enExample) |
| KR (4) | KR102366081B1 (enExample) |
| CN (2) | CN105612176B (enExample) |
| AU (2) | AU2013296564C1 (enExample) |
| CA (1) | CA2882028C (enExample) |
| ES (2) | ES2837487T3 (enExample) |
| SG (1) | SG11201500799YA (enExample) |
| WO (1) | WO2014022423A2 (enExample) |
Families Citing this family (25)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US20140134195A1 (en) | 2011-04-20 | 2014-05-15 | University Of Washington Through Its Center For Commercialization | Beta-2 microglobulin-deficient cells |
| SG11201500799YA (en) | 2012-07-31 | 2015-03-30 | Basil M Hantash | Hla g-modified cells and methods |
| US10927384B2 (en) | 2014-04-09 | 2021-02-23 | Dna Twopointo Inc. | DNA vectors, transposons and transposases for eukaryotic genome modification |
| CA2944887A1 (en) * | 2014-04-09 | 2015-10-15 | Jeremy Minshull | Enhanced polynucleotide constructs for eukaryotic gene expression |
| JP6836990B2 (ja) * | 2014-11-26 | 2021-03-03 | アクセラレイテッド・バイオサイエンシズ・コーポレーション | 誘導肝細胞およびそれらの使用 |
| AU2015360502A1 (en) | 2014-12-10 | 2017-06-29 | Regents Of The University Of Minnesota | Genetically modified cells, tissues, and organs for treating disease |
| US20220241345A1 (en) * | 2015-10-02 | 2022-08-04 | The Regents Of The University Of California | Induced pluripotent stem cell derived glial enriched progenitor cells for the treatment of white matter stroke |
| ES2891087T3 (es) | 2015-10-08 | 2022-01-26 | Dna Twopointo Inc | Vectores de ADN, trasposones y transposasas para la modificación del genoma eucariota |
| WO2017218714A1 (en) * | 2016-06-14 | 2017-12-21 | Regents Of The University Of Minnesota | Genetically modified cells, tissues, and organs for treating disease |
| JP2019521688A (ja) | 2016-07-26 | 2019-08-08 | ザ ユニバーシティ オブ ノース カロライナ アット チャペル ヒル | 眼におけるベクター介在の免疫寛容 |
| CN110268050B (zh) * | 2017-01-10 | 2024-09-13 | 综合医院公司 | 经修饰的t细胞和它们的使用方法 |
| GB2588249B (en) * | 2017-06-12 | 2023-01-04 | Sinai Health Sys | Allograft tolerance without the need for systemic immune suppression |
| CA3086923A1 (en) * | 2017-12-28 | 2019-07-04 | Gritstone Oncology, Inc. | Antigen-binding proteins targeting shared antigens |
| JP7241161B2 (ja) * | 2018-08-01 | 2023-03-16 | イミュニティーバイオ、インコーポレイテッド | 細胞免疫療法の安定した遺伝子改変のための、ホーミング受容体又はサイトカインとキメラ抗原受容体とを含むクアドリシストロニックシステム |
| US10883084B2 (en) | 2018-10-05 | 2021-01-05 | Xenotherapeutics, Inc. | Personalized cells, tissues, and organs for transplantation from a humanized, bespoke, designated-pathogen free, (non-human) donor and methods and products relating to same |
| EA202191673A1 (ru) * | 2018-12-14 | 2021-09-28 | Прометера Терапьютикс Са | Композиция на основе клеток, содержащая клетки-предшественники печени, экспрессирующие hla-e |
| WO2020120666A1 (en) | 2018-12-14 | 2020-06-18 | Promethera Biosciences S.A./N.V. | Liver progenitor cells expressing hla-g, and method for obtaining these cells compositions comprising said cells and their use |
| US11230699B2 (en) | 2020-01-28 | 2022-01-25 | Immunitybio, Inc. | Chimeric antigen receptor-modified NK-92 cells targeting EGFR super-family receptors |
| US20210246426A1 (en) * | 2020-02-10 | 2021-08-12 | Rubius Therapeutics, Inc. | Engineered Erythroid Cells Including HLA-G Polypeptides and Methods of Use Thereof |
| CA3185067A1 (en) * | 2020-05-26 | 2021-12-02 | Kouichi Tamura | Hypoimmunogenic cells |
| CN114746152A (zh) * | 2020-08-23 | 2022-07-12 | 应用干细胞有限公司 | Hla-f修饰的细胞和方法 |
| US11459372B2 (en) | 2020-11-30 | 2022-10-04 | Crispr Therapeutics Ag | Gene-edited natural killer cells |
| WO2022144632A1 (en) | 2020-12-30 | 2022-07-07 | Crispr Therapeutics Ag | Compositions and methods for differentiating stem cells into nk cells |
| CN113234664B (zh) * | 2021-05-11 | 2024-05-10 | 澳门大学 | 一种胰腺祖细胞的制备方法及其应用 |
| JP2024540987A (ja) * | 2021-10-21 | 2024-11-06 | バーテックス ファーマシューティカルズ インコーポレイテッド | 低免疫細胞 |
Family Cites Families (33)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CA1339354C (en) | 1988-09-01 | 1997-08-26 | The Whitehead Institute For Biomedical Research | Recombinant retroviruses with amphotropic and ecotropic host ranges |
| US5464764A (en) | 1989-08-22 | 1995-11-07 | University Of Utah Research Foundation | Positive-negative selection methods and vectors |
| US5534423A (en) | 1993-10-08 | 1996-07-09 | Regents Of The University Of Michigan | Methods of increasing rates of infection by directing motion of vectors |
| US6686198B1 (en) | 1993-10-14 | 2004-02-03 | President And Fellows Of Harvard College | Method of inducing and maintaining neuronal cells |
| US6013517A (en) | 1994-05-09 | 2000-01-11 | Chiron Corporation | Crossless retroviral vectors |
| US5650135A (en) | 1994-07-01 | 1997-07-22 | The Board Of Trustees Of The Leland Stanford Junior University | Non-invasive localization of a light-emitting conjugate in a mammal |
| US5843780A (en) | 1995-01-20 | 1998-12-01 | Wisconsin Alumni Research Foundation | Primate embryonic stem cells |
| US5741657A (en) | 1995-03-20 | 1998-04-21 | The Regents Of The University Of California | Fluorogenic substrates for β-lactamase and methods of use |
| US5744320A (en) | 1995-06-07 | 1998-04-28 | Promega Corporation | Quenching reagents and assays for enzyme-mediated luminescence |
| US6982431B2 (en) | 1998-08-31 | 2006-01-03 | Molecular Devices Corporation | Sample analysis systems |
| US6031094A (en) | 1998-07-23 | 2000-02-29 | The Regents Of The University Of California | Beta-lactam substrates and uses thereof |
| US7005252B1 (en) | 2000-03-09 | 2006-02-28 | Wisconsin Alumni Research Foundation | Serum free cultivation of primate embryonic stem cells |
| DE10291734D2 (de) | 2001-04-23 | 2004-05-27 | Lorbach Elke | Pufferlösung für die Elektroporation und Verfahren umfassend die Verwendung derselben |
| EP2361966A1 (en) | 2002-05-17 | 2011-08-31 | Mount Sinai School of Medicine of New York University | Mesoderm and definitive endoderm cell populations |
| AU2004211584B2 (en) | 2003-01-31 | 2009-11-12 | Promega Corporation | Covalent tethering of functional groups to proteins |
| US7960166B2 (en) | 2003-05-21 | 2011-06-14 | The General Hospital Corporation | Microfabricated compositions and processes for engineering tissues containing multiple cell types |
| EP1675956B1 (en) * | 2003-10-21 | 2010-10-13 | Merck Serono SA | Minimal dna sequence acting as a chromatin insulator and its use in protein expression |
| US8673634B2 (en) | 2003-11-13 | 2014-03-18 | Massachusetts Eye & Ear Infirmary | Method for the treatment of hearing loss |
| AU2005300503B2 (en) | 2004-11-08 | 2010-12-16 | Chromagenics B.V. | Selection of host cells expressing protein at high levels |
| US20070036773A1 (en) * | 2005-08-09 | 2007-02-15 | City Of Hope | Generation and application of universal T cells for B-ALL |
| CN101330935B (zh) * | 2005-10-21 | 2013-11-13 | 细胞研究私人有限公司 | 自脐带羊膜分离和培养干/祖细胞及其分化的细胞的应用 |
| EP4223769A3 (en) | 2005-12-13 | 2023-11-01 | Kyoto University | Nuclear reprogramming factor |
| US8278104B2 (en) | 2005-12-13 | 2012-10-02 | Kyoto University | Induced pluripotent stem cells produced with Oct3/4, Klf4 and Sox2 |
| US20090156532A1 (en) * | 2006-01-24 | 2009-06-18 | The University Of Chicago | SNP BINDING SITE FOR microRNAs IN HLA-G |
| WO2007091078A2 (en) * | 2006-02-10 | 2007-08-16 | Axordia Limited | Polypeptide conjugate comprising hla-g and uses thereof, stem cells transfected with hla-g |
| WO2008054821A2 (en) | 2006-10-30 | 2008-05-08 | Promega Corporation | Mutant hydrolase proteins with enhanced kinetics and functional expression |
| US8647871B2 (en) * | 2007-03-30 | 2014-02-11 | Escape Therapeutics, Inc. | Endogenous expression of HLA-G and/or HLA-E by mesenchymal cells |
| US20110263001A1 (en) * | 2008-11-14 | 2011-10-27 | Life Technologies Corporation | Compositions and Methods for Engineering Cells |
| US8592211B2 (en) | 2009-03-20 | 2013-11-26 | The Rockefeller University | Enhanced PiggyBac transposon and methods for transposon mutagenesis |
| US8048675B1 (en) | 2010-05-12 | 2011-11-01 | Ipierian, Inc. | Integration-free human induced pluripotent stem cells from blood |
| SG11201500799YA (en) | 2012-07-31 | 2015-03-30 | Basil M Hantash | Hla g-modified cells and methods |
| CN103333861A (zh) * | 2013-06-03 | 2013-10-02 | 浙江省台州医院 | 特异性表达hla-g1抗原的细胞株k562 |
| CN111808819A (zh) * | 2020-05-26 | 2020-10-23 | 台州恩泽医疗中心(集团) | 表达hla-g3异构体标准蛋白的细胞株及其应用 |
-
2013
- 2013-07-30 SG SG11201500799YA patent/SG11201500799YA/en unknown
- 2013-07-30 JP JP2015525519A patent/JP6297559B2/ja active Active
- 2013-07-30 EP EP20196775.9A patent/EP3805261A1/en not_active Withdrawn
- 2013-07-30 ES ES18211100T patent/ES2837487T3/es active Active
- 2013-07-30 ES ES13825511T patent/ES2716577T3/es active Active
- 2013-07-30 CN CN201380051169.3A patent/CN105612176B/zh active Active
- 2013-07-30 CN CN202110063720.2A patent/CN113151179A/zh active Pending
- 2013-07-30 WO PCT/US2013/052767 patent/WO2014022423A2/en not_active Ceased
- 2013-07-30 EP EP21209423.9A patent/EP4015530A1/en active Pending
- 2013-07-30 KR KR1020207033804A patent/KR102366081B1/ko active Active
- 2013-07-30 EP EP18211100.5A patent/EP3483178B1/en active Active
- 2013-07-30 CA CA2882028A patent/CA2882028C/en active Active
- 2013-07-30 KR KR1020157005165A patent/KR101923632B1/ko active Active
- 2013-07-30 KR KR1020197036122A patent/KR102184947B1/ko active Active
- 2013-07-30 EP EP13825511.2A patent/EP2880054B1/en active Active
- 2013-07-30 KR KR1020187034048A patent/KR102055438B1/ko active Active
- 2013-07-30 AU AU2013296564A patent/AU2013296564C1/en active Active
-
2015
- 2015-01-28 US US14/608,004 patent/US9714280B2/en active Active
-
2017
- 2017-06-16 US US15/625,964 patent/US10502738B2/en active Active
-
2018
- 2018-02-21 JP JP2018028816A patent/JP6502544B2/ja active Active
- 2018-08-23 AU AU2018220087A patent/AU2018220087B2/en active Active
-
2019
- 2019-03-20 JP JP2019052699A patent/JP7294838B2/ja active Active
- 2019-10-22 US US16/659,918 patent/US11977073B2/en active Active
-
2020
- 2020-03-27 US US16/832,321 patent/US20200309776A1/en not_active Abandoned
-
2021
- 2021-04-14 JP JP2021068195A patent/JP7379410B2/ja active Active
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