JP2015529457A5 - - Google Patents
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- Publication number
- JP2015529457A5 JP2015529457A5 JP2015525519A JP2015525519A JP2015529457A5 JP 2015529457 A5 JP2015529457 A5 JP 2015529457A5 JP 2015525519 A JP2015525519 A JP 2015525519A JP 2015525519 A JP2015525519 A JP 2015525519A JP 2015529457 A5 JP2015529457 A5 JP 2015529457A5
- Authority
- JP
- Japan
- Prior art keywords
- genetically modified
- hla
- cell
- nucleic acid
- acid sequence
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201261677739P | 2012-07-31 | 2012-07-31 | |
| US61/677,739 | 2012-07-31 | ||
| PCT/US2013/052767 WO2014022423A2 (en) | 2012-07-31 | 2013-07-30 | Hla g-modified cells and methods |
Related Child Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2018028816A Division JP6502544B2 (ja) | 2012-07-31 | 2018-02-21 | Ｈｌａ ｇ改変された細胞および方法 |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2015529457A JP2015529457A (ja) | 2015-10-08 |
| JP2015529457A5 true JP2015529457A5 (enExample) | 2016-09-15 |
| JP6297559B2 JP6297559B2 (ja) | 2018-03-20 |
Family
ID=50028654
Family Applications (4)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2015525519A Active JP6297559B2 (ja) | 2012-07-31 | 2013-07-30 | Ｈｌａｇ改変された細胞および方法 |
| JP2018028816A Active JP6502544B2 (ja) | 2012-07-31 | 2018-02-21 | Ｈｌａ ｇ改変された細胞および方法 |
| JP2019052699A Active JP7294838B2 (ja) | 2012-07-31 | 2019-03-20 | Ｈｌａ ｇ改変された細胞および方法 |
| JP2021068195A Active JP7379410B2 (ja) | 2012-07-31 | 2021-04-14 | Ｈｌａ ｇ改変された細胞および方法 |
Family Applications After (3)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2018028816A Active JP6502544B2 (ja) | 2012-07-31 | 2018-02-21 | Ｈｌａ ｇ改変された細胞および方法 |
| JP2019052699A Active JP7294838B2 (ja) | 2012-07-31 | 2019-03-20 | Ｈｌａ ｇ改変された細胞および方法 |
| JP2021068195A Active JP7379410B2 (ja) | 2012-07-31 | 2021-04-14 | Ｈｌａ ｇ改変された細胞および方法 |
Country Status (10)
| Country | Link |
|---|---|
| US (4) | US9714280B2 (enExample) |
| EP (4) | EP2880054B1 (enExample) |
| JP (4) | JP6297559B2 (enExample) |
| KR (4) | KR102366081B1 (enExample) |
| CN (2) | CN105612176B (enExample) |
| AU (2) | AU2013296564C1 (enExample) |
| CA (1) | CA2882028C (enExample) |
| ES (2) | ES2716577T3 (enExample) |
| SG (1) | SG11201500799YA (enExample) |
| WO (1) | WO2014022423A2 (enExample) |
Families Citing this family (30)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DK2699593T4 (da) | 2011-04-20 | 2021-02-08 | Univ Washington Through Its Center For Commercialization | Beta-2 mikroglobulin-deficiente celler |
| EP4253409A3 (en) | 2012-04-17 | 2023-12-06 | University of Washington through its Center for Commercialization | Hla class ii deficient cells, hla class i deficient cells capable of expressing hla class ii proteins, and uses thereof |
| SG11201500799YA (en) | 2012-07-31 | 2015-03-30 | Basil M Hantash | Hla g-modified cells and methods |
| HUE052552T2 (hu) | 2014-04-09 | 2021-05-28 | Dna Twopointo Inc | Javított nukleinsav-konstrukciók eukarióta génexpresszióhoz |
| US10927384B2 (en) | 2014-04-09 | 2021-02-23 | Dna Twopointo Inc. | DNA vectors, transposons and transposases for eukaryotic genome modification |
| GB2548059B (en) * | 2014-11-26 | 2020-09-02 | Accelerated Biosciences Corp | Induced hepatocytes and uses thereof |
| WO2016094679A1 (en) | 2014-12-10 | 2016-06-16 | Regents Of The University Of Minnesota | Genetically modified cells, tissues, and organs for treating disease |
| WO2017058819A1 (en) | 2015-10-02 | 2017-04-06 | The Regents Of The University Of California | Induced pluripotent stem cell derived glial enriched progenitor cells for the treatment of white matter stroke |
| US20220241345A1 (en) * | 2015-10-02 | 2022-08-04 | The Regents Of The University Of California | Induced pluripotent stem cell derived glial enriched progenitor cells for the treatment of white matter stroke |
| LT3359671T (lt) | 2015-10-08 | 2021-12-10 | Dna Twopointo Inc. | Dnr vektoriai, transpozonai ir transpozazės, skirti eukariotinio genomo modifikacijai |
| CA3027428A1 (en) * | 2016-06-14 | 2017-12-21 | Regents Of The University Of Minnesota | Genetically modified cells, tissues, and organs for treating disease |
| AU2017301705A1 (en) | 2016-07-26 | 2019-01-24 | North Carolina State University | Vector-mediated immune tolerance in the eye |
| AU2018208614A1 (en) * | 2017-01-10 | 2019-07-11 | The General Hospital Corporation | Modified T cells and methods of their use |
| CN110869494B (zh) * | 2017-06-12 | 2025-02-18 | 西奈卫生系统公司 | 无需全身性免疫遏制的同种异体移植物耐受 |
| AU2018395397A1 (en) * | 2017-12-28 | 2020-08-06 | Gritstone Bio, Inc. | Antigen-binding proteins targeting shared antigens |
| KR102907902B1 (ko) * | 2018-08-01 | 2026-01-02 | 난트퀘스트, 인크. | 면역 요법의 안정한 유전적 변형을 위한 귀소 수용체 또는 사이토카인, 및 키메라 항원 수용체를 포함하는 4 시스트론 시스템 |
| US10883084B2 (en) | 2018-10-05 | 2021-01-05 | Xenotherapeutics, Inc. | Personalized cells, tissues, and organs for transplantation from a humanized, bespoke, designated-pathogen free, (non-human) donor and methods and products relating to same |
| CA3123102A1 (en) | 2018-12-13 | 2020-06-18 | Sinai Health System | Immunomodulatory cells and uses thereof |
| MX2021006773A (es) * | 2018-12-14 | 2021-09-21 | Promethera Therapeutics Sa | Composicion celular que comprende celulas progenitoras del higado que expresan hla-e. |
| WO2020120666A1 (en) | 2018-12-14 | 2020-06-18 | Promethera Biosciences S.A./N.V. | Liver progenitor cells expressing hla-g, and method for obtaining these cells compositions comprising said cells and their use |
| US11230699B2 (en) | 2020-01-28 | 2022-01-25 | Immunitybio, Inc. | Chimeric antigen receptor-modified NK-92 cells targeting EGFR super-family receptors |
| EP4103696A1 (en) * | 2020-02-10 | 2022-12-21 | Rubius Therapeutics, Inc. | Engineered erythroid cells including hla-g polypeptides and methods of use thereof |
| US20230203445A1 (en) * | 2020-05-26 | 2023-06-29 | Healios K.K. | Hypoimmunogenic cells |
| CN114746152A (zh) * | 2020-08-23 | 2022-07-12 | 应用干细胞有限公司 | Hla-f修饰的细胞和方法 |
| WO2022082030A2 (en) | 2020-10-15 | 2022-04-21 | Gritstone Bio, Inc. | Antigen-binding proteins and related methods of use |
| US11459372B2 (en) | 2020-11-30 | 2022-10-04 | Crispr Therapeutics Ag | Gene-edited natural killer cells |
| EP4271798A1 (en) | 2020-12-30 | 2023-11-08 | CRISPR Therapeutics AG | Compositions and methods for differentiating stem cells into nk cells |
| WO2022155503A1 (en) | 2021-01-14 | 2022-07-21 | Gritstone Bio, Inc. | Multi-specific antibodies and methods of use |
| CN113234664B (zh) * | 2021-05-11 | 2024-05-10 | 澳门大学 | 一种胰腺祖细胞的制备方法及其应用 |
| JP2024540987A (ja) * | 2021-10-21 | 2024-11-06 | バーテックス ファーマシューティカルズ インコーポレイテッド | 低免疫細胞 |
Family Cites Families (33)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO1990002806A1 (en) | 1988-09-01 | 1990-03-22 | Whitehead Institute For Biomedical Research | Recombinant retroviruses with amphotropic and ecotropic host ranges |
| US5464764A (en) | 1989-08-22 | 1995-11-07 | University Of Utah Research Foundation | Positive-negative selection methods and vectors |
| US5534423A (en) | 1993-10-08 | 1996-07-09 | Regents Of The University Of Michigan | Methods of increasing rates of infection by directing motion of vectors |
| US6686198B1 (en) | 1993-10-14 | 2004-02-03 | President And Fellows Of Harvard College | Method of inducing and maintaining neuronal cells |
| US6013517A (en) | 1994-05-09 | 2000-01-11 | Chiron Corporation | Crossless retroviral vectors |
| US5650135A (en) | 1994-07-01 | 1997-07-22 | The Board Of Trustees Of The Leland Stanford Junior University | Non-invasive localization of a light-emitting conjugate in a mammal |
| US5843780A (en) | 1995-01-20 | 1998-12-01 | Wisconsin Alumni Research Foundation | Primate embryonic stem cells |
| US5741657A (en) | 1995-03-20 | 1998-04-21 | The Regents Of The University Of California | Fluorogenic substrates for β-lactamase and methods of use |
| US5744320A (en) | 1995-06-07 | 1998-04-28 | Promega Corporation | Quenching reagents and assays for enzyme-mediated luminescence |
| US6982431B2 (en) | 1998-08-31 | 2006-01-03 | Molecular Devices Corporation | Sample analysis systems |
| US6031094A (en) | 1998-07-23 | 2000-02-29 | The Regents Of The University Of California | Beta-lactam substrates and uses thereof |
| US7005252B1 (en) | 2000-03-09 | 2006-02-28 | Wisconsin Alumni Research Foundation | Serum free cultivation of primate embryonic stem cells |
| JP4070611B2 (ja) | 2001-04-23 | 2008-04-02 | アマクサ アーゲー | 電気穿孔法用の緩衝溶液およびその使用を含む方法 |
| US7763466B2 (en) | 2002-05-17 | 2010-07-27 | Mount Sinai School Of Medicine Of New York University | Mesoderm and definitive endoderm cell populations |
| KR20050109934A (ko) | 2003-01-31 | 2005-11-22 | 프로메가 코포레이션 | 관능기의 단백질로의 공유 테더링 |
| US7960166B2 (en) | 2003-05-21 | 2011-06-14 | The General Hospital Corporation | Microfabricated compositions and processes for engineering tissues containing multiple cell types |
| CA2541523A1 (en) * | 2003-10-21 | 2005-05-06 | Applied Research Systems Ars Holding N.V. | Minimal dna sequence acting as a chromatin insulator and its use in protein expression |
| US8673634B2 (en) | 2003-11-13 | 2014-03-18 | Massachusetts Eye & Ear Infirmary | Method for the treatment of hearing loss |
| BRPI0517380A (pt) | 2004-11-08 | 2008-10-07 | Chromagenics Bv | molécula de dna, cassete de expressão, célula hospedeira, e, métodos para gerar uma célula hospedeira que expressa um polipeptìdeo de interesse e para produzir um polipeptìdeo de interesse |
| US20070036773A1 (en) * | 2005-08-09 | 2007-02-15 | City Of Hope | Generation and application of universal T cells for B-ALL |
| CN101330935B (zh) * | 2005-10-21 | 2013-11-13 | 细胞研究私人有限公司 | 自脐带羊膜分离和培养干/祖细胞及其分化的细胞的应用 |
| EP2206724A1 (en) | 2005-12-13 | 2010-07-14 | Kyoto University | Nuclear reprogramming factor |
| US8278104B2 (en) | 2005-12-13 | 2012-10-02 | Kyoto University | Induced pluripotent stem cells produced with Oct3/4, Klf4 and Sox2 |
| WO2007087539A2 (en) * | 2006-01-24 | 2007-08-02 | The University Of Chicago | Snp binding site for micrornas in hla-g |
| WO2007091078A2 (en) * | 2006-02-10 | 2007-08-16 | Axordia Limited | Polypeptide conjugate comprising hla-g and uses thereof, stem cells transfected with hla-g |
| EP2374875B1 (en) | 2006-10-30 | 2015-09-02 | Promega Corporation | Mutant hydrolase proteins with enhanced kinetics and funcitional expression |
| US8647871B2 (en) * | 2007-03-30 | 2014-02-11 | Escape Therapeutics, Inc. | Endogenous expression of HLA-G and/or HLA-E by mesenchymal cells |
| JP2012508591A (ja) * | 2008-11-14 | 2012-04-12 | ライフ テクノロジーズ コーポレーション | 細胞を操作するための組成物および方法 |
| US8592211B2 (en) | 2009-03-20 | 2013-11-26 | The Rockefeller University | Enhanced PiggyBac transposon and methods for transposon mutagenesis |
| US8048675B1 (en) | 2010-05-12 | 2011-11-01 | Ipierian, Inc. | Integration-free human induced pluripotent stem cells from blood |
| SG11201500799YA (en) | 2012-07-31 | 2015-03-30 | Basil M Hantash | Hla g-modified cells and methods |
| CN103333861A (zh) * | 2013-06-03 | 2013-10-02 | 浙江省台州医院 | 特异性表达hla-g1抗原的细胞株k562 |
| CN111808819A (zh) * | 2020-05-26 | 2020-10-23 | 台州恩泽医疗中心(集团) | 表达hla-g3异构体标准蛋白的细胞株及其应用 |
-
2013
- 2013-07-30 SG SG11201500799YA patent/SG11201500799YA/en unknown
- 2013-07-30 KR KR1020207033804A patent/KR102366081B1/ko active Active
- 2013-07-30 EP EP13825511.2A patent/EP2880054B1/en active Active
- 2013-07-30 KR KR1020187034048A patent/KR102055438B1/ko active Active
- 2013-07-30 ES ES13825511T patent/ES2716577T3/es active Active
- 2013-07-30 WO PCT/US2013/052767 patent/WO2014022423A2/en not_active Ceased
- 2013-07-30 CA CA2882028A patent/CA2882028C/en active Active
- 2013-07-30 KR KR1020157005165A patent/KR101923632B1/ko active Active
- 2013-07-30 EP EP18211100.5A patent/EP3483178B1/en active Active
- 2013-07-30 CN CN201380051169.3A patent/CN105612176B/zh not_active Expired - Fee Related
- 2013-07-30 JP JP2015525519A patent/JP6297559B2/ja active Active
- 2013-07-30 EP EP21209423.9A patent/EP4015530A1/en not_active Withdrawn
- 2013-07-30 ES ES18211100T patent/ES2837487T3/es active Active
- 2013-07-30 EP EP20196775.9A patent/EP3805261A1/en not_active Withdrawn
- 2013-07-30 CN CN202110063720.2A patent/CN113151179A/zh active Pending
- 2013-07-30 AU AU2013296564A patent/AU2013296564C1/en not_active Ceased
- 2013-07-30 KR KR1020197036122A patent/KR102184947B1/ko active Active
-
2015
- 2015-01-28 US US14/608,004 patent/US9714280B2/en active Active
-
2017
- 2017-06-16 US US15/625,964 patent/US10502738B2/en active Active
-
2018
- 2018-02-21 JP JP2018028816A patent/JP6502544B2/ja active Active
- 2018-08-23 AU AU2018220087A patent/AU2018220087B2/en not_active Ceased
-
2019
- 2019-03-20 JP JP2019052699A patent/JP7294838B2/ja active Active
- 2019-10-22 US US16/659,918 patent/US11977073B2/en active Active
-
2020
- 2020-03-27 US US16/832,321 patent/US20200309776A1/en not_active Abandoned
-
2021
- 2021-04-14 JP JP2021068195A patent/JP7379410B2/ja active Active
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