JP2015528282A5 - - Google Patents
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- JP2015528282A5 JP2015528282A5 JP2015525957A JP2015525957A JP2015528282A5 JP 2015528282 A5 JP2015528282 A5 JP 2015528282A5 JP 2015525957 A JP2015525957 A JP 2015525957A JP 2015525957 A JP2015525957 A JP 2015525957A JP 2015528282 A5 JP2015528282 A5 JP 2015528282A5
- Authority
- JP
- Japan
- Prior art keywords
- nanostructure
- sensor
- sensitive
- assay
- assay region
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Ceased
Links
- 238000003556 assay Methods 0.000 claims 21
- 108091033319 polynucleotide Proteins 0.000 claims 19
- 102000040430 polynucleotide Human genes 0.000 claims 19
- 238000000034 method Methods 0.000 claims 17
- 239000002086 nanomaterial Substances 0.000 claims 17
- 239000002157 polynucleotide Substances 0.000 claims 10
- 239000002090 nanochannel Substances 0.000 claims 7
- OKTJSMMVPCPJKN-UHFFFAOYSA-N Carbon Chemical compound [C] OKTJSMMVPCPJKN-UHFFFAOYSA-N 0.000 claims 5
- 239000000523 sample Substances 0.000 claims 5
- 238000012163 sequencing technique Methods 0.000 claims 5
- 239000000243 solution Substances 0.000 claims 5
- 239000012472 biological sample Substances 0.000 claims 4
- 102000039446 nucleic acids Human genes 0.000 claims 4
- 108020004707 nucleic acids Proteins 0.000 claims 4
- 150000007523 nucleic acids Chemical class 0.000 claims 4
- 238000011896 sensitive detection Methods 0.000 claims 4
- 229910021389 graphene Inorganic materials 0.000 claims 3
- 108091093094 Glycol nucleic acid Proteins 0.000 claims 2
- 108091093037 Peptide nucleic acid Proteins 0.000 claims 2
- 239000002253 acid Substances 0.000 claims 2
- 239000012491 analyte Substances 0.000 claims 2
- 239000002041 carbon nanotube Substances 0.000 claims 2
- 229910021393 carbon nanotube Inorganic materials 0.000 claims 2
- 239000000284 extract Substances 0.000 claims 2
- 239000012530 fluid Substances 0.000 claims 2
- 239000007789 gas Substances 0.000 claims 2
- 239000002070 nanowire Substances 0.000 claims 2
- 239000002773 nucleotide Substances 0.000 claims 2
- 125000003729 nucleotide group Chemical group 0.000 claims 2
- 230000008569 process Effects 0.000 claims 2
- 230000007704 transition Effects 0.000 claims 2
- 229910018072 Al 2 O 3 Inorganic materials 0.000 claims 1
- 241000895511 Nanostoma Species 0.000 claims 1
- 229910004298 SiO 2 Inorganic materials 0.000 claims 1
- 108091046915 Threose nucleic acid Proteins 0.000 claims 1
- 230000003321 amplification Effects 0.000 claims 1
- 238000000137 annealing Methods 0.000 claims 1
- 210000001124 body fluid Anatomy 0.000 claims 1
- 239000000872 buffer Substances 0.000 claims 1
- 239000007853 buffer solution Substances 0.000 claims 1
- 230000008859 change Effects 0.000 claims 1
- 230000009089 cytolysis Effects 0.000 claims 1
- 238000000151 deposition Methods 0.000 claims 1
- 230000008021 deposition Effects 0.000 claims 1
- 238000000979 dip-pen nanolithography Methods 0.000 claims 1
- 238000010894 electron beam technology Methods 0.000 claims 1
- 238000004049 embossing Methods 0.000 claims 1
- 238000005530 etching Methods 0.000 claims 1
- 230000005669 field effect Effects 0.000 claims 1
- 230000003993 interaction Effects 0.000 claims 1
- 238000010849 ion bombardment Methods 0.000 claims 1
- 238000010884 ion-beam technique Methods 0.000 claims 1
- 239000002207 metabolite Substances 0.000 claims 1
- 229910021645 metal ion Inorganic materials 0.000 claims 1
- 238000003801 milling Methods 0.000 claims 1
- 125000004573 morpholin-4-yl group Chemical group N1(CCOCC1)* 0.000 claims 1
- 238000003199 nucleic acid amplification method Methods 0.000 claims 1
- 238000000206 photolithography Methods 0.000 claims 1
- 229920002120 photoresistant polymer Polymers 0.000 claims 1
- 229920000642 polymer Polymers 0.000 claims 1
- 239000002861 polymer material Substances 0.000 claims 1
- 108090000623 proteins and genes Proteins 0.000 claims 1
- 102000004169 proteins and genes Human genes 0.000 claims 1
- 230000004044 response Effects 0.000 claims 1
- 229920002477 rna polymer Polymers 0.000 claims 1
- 230000035945 sensitivity Effects 0.000 claims 1
- 238000000926 separation method Methods 0.000 claims 1
- 238000000859 sublimation Methods 0.000 claims 1
- 230000008022 sublimation Effects 0.000 claims 1
- 238000003239 susceptibility assay Methods 0.000 claims 1
- 238000003631 wet chemical etching Methods 0.000 claims 1
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201261680212P | 2012-08-06 | 2012-08-06 | |
| US61/680,212 | 2012-08-06 | ||
| PCT/IB2013/002168 WO2014024041A1 (en) | 2012-08-06 | 2013-08-05 | Method and kit for nucleic acid sequencing |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2015528282A JP2015528282A (ja) | 2015-09-28 |
| JP2015528282A5 true JP2015528282A5 (enExample) | 2016-09-23 |
Family
ID=49354708
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2015525957A Ceased JP2015528282A (ja) | 2012-08-06 | 2013-08-05 | 核酸シークエンシングのための方法およびキット |
Country Status (7)
| Country | Link |
|---|---|
| US (1) | US20150276709A1 (enExample) |
| EP (1) | EP2879793A1 (enExample) |
| JP (1) | JP2015528282A (enExample) |
| CN (1) | CN104703700B (enExample) |
| HK (1) | HK1211260A1 (enExample) |
| IN (1) | IN2015DN01300A (enExample) |
| WO (1) | WO2014024041A1 (enExample) |
Families Citing this family (48)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP2321429B1 (en) | 2008-09-03 | 2016-08-17 | Quantumdx Group Limited | Methods and kits for nucleic acid sequencing |
| US10759824B2 (en) | 2008-09-03 | 2020-09-01 | Quantumdx Group Limited | Design, synthesis and use of synthetic nucleotides comprising charge mass tags |
| WO2014182630A1 (en) | 2013-05-06 | 2014-11-13 | Pacific Biosciences Of California , Inc. | Real-time electronic sequencing |
| US9618476B2 (en) * | 2014-04-28 | 2017-04-11 | Nanomedical Diagnostics, Inc. | System and method for electronic biological sample analysis |
| US9765395B2 (en) | 2014-04-28 | 2017-09-19 | Nanomedical Diagnostics, Inc. | System and method for DNA sequencing and blood chemistry analysis |
| US11215580B2 (en) | 2014-04-28 | 2022-01-04 | Cardea Bio, Inc. | System and method for DNA sequencing and blood chemistry analysis |
| US20160054312A1 (en) | 2014-04-28 | 2016-02-25 | Nanomedical Diagnostics, Inc. | Chemically differentiated sensor array |
| CN105624020B (zh) * | 2014-11-07 | 2017-11-03 | 深圳华大基因研究院 | 用于检测dna片段的碱基序列的微流控芯片 |
| US12298301B2 (en) | 2014-12-18 | 2025-05-13 | Cardea Bio, Inc. | Chemically-sensitive field effect transistors, systems, and methods for manufacturing and using the same |
| US11921112B2 (en) | 2014-12-18 | 2024-03-05 | Paragraf Usa Inc. | Chemically-sensitive field effect transistors, systems, and methods for manufacturing and using the same |
| US9857328B2 (en) | 2014-12-18 | 2018-01-02 | Agilome, Inc. | Chemically-sensitive field effect transistors, systems and methods for manufacturing and using the same |
| CA2971589C (en) | 2014-12-18 | 2021-09-28 | Edico Genome Corporation | Chemically-sensitive field effect transistor |
| US9859394B2 (en) | 2014-12-18 | 2018-01-02 | Agilome, Inc. | Graphene FET devices, systems, and methods of using the same for sequencing nucleic acids |
| US11782057B2 (en) | 2014-12-18 | 2023-10-10 | Cardea Bio, Inc. | Ic with graphene fet sensor array patterned in layers above circuitry formed in a silicon based cmos wafer |
| US10020300B2 (en) | 2014-12-18 | 2018-07-10 | Agilome, Inc. | Graphene FET devices, systems, and methods of using the same for sequencing nucleic acids |
| US10006910B2 (en) | 2014-12-18 | 2018-06-26 | Agilome, Inc. | Chemically-sensitive field effect transistors, systems, and methods for manufacturing and using the same |
| US9618474B2 (en) | 2014-12-18 | 2017-04-11 | Edico Genome, Inc. | Graphene FET devices, systems, and methods of using the same for sequencing nucleic acids |
| HK1245348A1 (zh) * | 2015-02-02 | 2018-08-24 | 奥特拉公司 | 来自样品背景的靶多核苷酸的纳米孔隙检测 |
| CN104778964A (zh) * | 2015-04-03 | 2015-07-15 | 程志 | 一种用于疾病诊断的检测u盘 |
| KR101958053B1 (ko) * | 2015-06-08 | 2019-03-13 | 고려대학교 산학협력단 | 원자 또는 이온을 선택적으로 투과시키는 필터용 나노 채널 구조물 및 이의 제조 방법 |
| CA3021580A1 (en) * | 2015-06-25 | 2016-12-29 | Barry L. Merriman | Biomolecular sensors and methods |
| US10190158B2 (en) | 2015-08-06 | 2019-01-29 | Pacific Biosciences Of California, Inc. | Systems and methods for selectively addressing sparsely arranged electronic measurement devices |
| EP3400444A4 (en) | 2016-01-04 | 2019-10-16 | QuantuMDx Group Limited | DESIGN, SYNTHESIS AND USE OF SYNTHETIC NUCLEOTIDES WITH LOADING MASS MARKINGS |
| CA3050062A1 (en) | 2016-01-14 | 2017-07-20 | Roswell Biotechnologies, Inc. | Molecular sensors and related methods |
| EP3408219B1 (en) | 2016-01-28 | 2022-08-17 | Roswell Biotechnologies, Inc | Massively parallel dna sequencing apparatus |
| JP7280590B2 (ja) | 2016-01-28 | 2023-05-24 | ロズウェル バイオテクノロジーズ，インコーポレイテッド | 大スケールの分子電子工学センサアレイを使用する被分析物を測定するための方法および装置 |
| CN106191230A (zh) * | 2016-02-02 | 2016-12-07 | 杭州格磊思沃科技有限公司 | 用氨基酸结合脱氧核苷酸进行dna测序的方法 |
| US10737263B2 (en) | 2016-02-09 | 2020-08-11 | Roswell Biotechnologies, Inc. | Electronic label-free DNA and genome sequencing |
| US10597767B2 (en) | 2016-02-22 | 2020-03-24 | Roswell Biotechnologies, Inc. | Nanoparticle fabrication |
| WO2017176584A1 (en) * | 2016-04-04 | 2017-10-12 | Coyote Bioscience Usa Inc. | Systems and methods for heating biological samples |
| WO2017201081A1 (en) | 2016-05-16 | 2017-11-23 | Agilome, Inc. | Graphene fet devices, systems, and methods of using the same for sequencing nucleic acids |
| US9829456B1 (en) | 2016-07-26 | 2017-11-28 | Roswell Biotechnologies, Inc. | Method of making a multi-electrode structure usable in molecular sensing devices |
| WO2018132457A1 (en) | 2017-01-10 | 2018-07-19 | Roswell Biotechnologies, Inc. | Methods and systems for dna data storage |
| CN110520517A (zh) | 2017-01-19 | 2019-11-29 | 罗斯威尔生命技术公司 | 包括二维层材料的固态测序装置 |
| US10508296B2 (en) | 2017-04-25 | 2019-12-17 | Roswell Biotechnologies, Inc. | Enzymatic circuits for molecular sensors |
| KR102879682B1 (ko) | 2017-04-25 | 2025-10-30 | 로스웰 엠이 아이엔씨. | 분자 센서들을 위한 효소 회로들 |
| CA3057155A1 (en) | 2017-05-09 | 2018-11-15 | Roswell Biotechnologies, Inc. | Binding probe circuits for molecular sensors |
| WO2018213459A1 (en) * | 2017-05-16 | 2018-11-22 | Wisconsin Alumni Research Foundation | System and method for en masse patterning of molecule structures |
| CN107475072B (zh) * | 2017-08-24 | 2020-12-11 | 浙江理工大学 | 基于三维石墨烯界面电极的细胞动态特性监测系统及方法 |
| EP3676389A4 (en) | 2017-08-30 | 2021-06-02 | Roswell Biotechnologies, Inc | PROCESSIVE ENZYMATIC MOLECULAR ELECTRONIC SENSORS FOR STORING DNA DATA |
| EP3694990A4 (en) | 2017-10-10 | 2022-06-15 | Roswell Biotechnologies, Inc. | METHODS, DEVICE AND SYSTEMS FOR AMPLIFICATION-FREE DNA DATA STORAGE |
| US11099136B2 (en) * | 2017-12-22 | 2021-08-24 | Regents Of The University Of Minnesota | 3D graphene optical sensors and methods of manufacture |
| DE102018207098B4 (de) | 2018-05-08 | 2024-06-13 | Robert Bosch Gmbh | Mikrofluidische Vorrichtung und Verfahren zur Nanostruktur-Sequenzierung von Nukleotidsträngen |
| DE102018207106B4 (de) * | 2018-05-08 | 2024-06-13 | Robert Bosch Gmbh | Mikrofluidische Sequenzierungsvorrichtung zum Vervielfältigen und Trennen von Molekülketten und Verfahren zum Trennen von aus einer Amplifikationsreaktion gewonnen Molekülketten |
| US11561197B2 (en) | 2018-06-29 | 2023-01-24 | AMMR Joint Venture | Electronic detection of a target based on enzymatic cleavage of a reporter moiety |
| GB201821210D0 (en) * | 2018-12-24 | 2019-02-06 | Univ College Dublin Nat Univ Ireland Dublin | Charge transfer template |
| JP7805957B2 (ja) * | 2020-05-15 | 2026-01-26 | ヘメミクス・バイオテクノロジーズ・インコーポレイテッド | 迅速なポイント・オブ・ケア診断のための多重バイオセンサー |
| WO2023123314A1 (zh) * | 2021-12-31 | 2023-07-06 | 京东方科技集团股份有限公司 | 微纳流控基板、芯片、制备方法及系统 |
Family Cites Families (15)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US7005264B2 (en) * | 2002-05-20 | 2006-02-28 | Intel Corporation | Method and apparatus for nucleic acid sequencing and identification |
| US7238594B2 (en) * | 2003-12-11 | 2007-07-03 | The Penn State Research Foundation | Controlled nanowire growth in permanent, integrated nano-templates and methods of fabricating sensor and transducer structures |
| US20060275779A1 (en) * | 2005-06-03 | 2006-12-07 | Zhiyong Li | Method and apparatus for molecular analysis using nanowires |
| EP2604344A3 (en) * | 2007-03-28 | 2014-07-16 | BioNano Genomics, Inc. | Methods of macromolecular analysis using nanochannel arrays |
| EP2014761B1 (en) * | 2007-06-22 | 2016-09-28 | Sony Deutschland GmbH | A device for processing an analyte and a method of processing and/or detecting an analyte using said device |
| US20110281740A1 (en) * | 2008-06-30 | 2011-11-17 | Joseph Beechem | Methods for Real Time Single Molecule Sequencing |
| EP3002288B1 (en) | 2008-09-03 | 2019-12-04 | Quantumdx Group Limited | Design, synthesis and use of synthetic nucleotides comprising ionic reporter groups |
| CN102186989B (zh) * | 2008-09-03 | 2021-06-29 | 纳伯塞斯2.0有限责任公司 | 用于流体通道中生物分子和其它分析物的电压感测的纵向移位纳米级电极的使用 |
| EP2321429B1 (en) * | 2008-09-03 | 2016-08-17 | Quantumdx Group Limited | Methods and kits for nucleic acid sequencing |
| EP3075867B1 (en) | 2008-09-03 | 2019-03-13 | Quantumdx Group Limited | Sensing strategies and methods for nucleic acid detection using biosensors |
| JP5586001B2 (ja) * | 2009-08-26 | 2014-09-10 | 独立行政法人物質・材料研究機構 | ナノリボン及びその製造方法、ナノリボンを用いたｆｅｔ及びその製造方法、ナノリボンを用いた塩基配列決定方法およびその装置 |
| EP2521796B1 (en) * | 2010-01-04 | 2015-07-29 | Life Technologies Corporation | Dna sequencing methods and detectors and systems for carrying out the same |
| US8715933B2 (en) * | 2010-09-27 | 2014-05-06 | Nabsys, Inc. | Assay methods using nicking endonucleases |
| CN102242062B (zh) * | 2011-04-19 | 2012-12-19 | 浙江大学 | 一种高分辨率的生物传感器 |
| CN202284206U (zh) * | 2011-08-02 | 2012-06-27 | 浙江大学 | 一种高分辨率的生物传感器 |
-
2013
- 2013-08-05 JP JP2015525957A patent/JP2015528282A/ja not_active Ceased
- 2013-08-05 WO PCT/IB2013/002168 patent/WO2014024041A1/en not_active Ceased
- 2013-08-05 HK HK15112192.4A patent/HK1211260A1/xx unknown
- 2013-08-05 IN IN1300DEN2015 patent/IN2015DN01300A/en unknown
- 2013-08-05 US US14/419,905 patent/US20150276709A1/en not_active Abandoned
- 2013-08-05 EP EP13776557.4A patent/EP2879793A1/en not_active Withdrawn
- 2013-08-05 CN CN201380051830.0A patent/CN104703700B/zh not_active Expired - Fee Related
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