JP2015526725A5 - - Google Patents
Download PDFInfo
- Publication number
- JP2015526725A5 JP2015526725A5 JP2015527420A JP2015527420A JP2015526725A5 JP 2015526725 A5 JP2015526725 A5 JP 2015526725A5 JP 2015527420 A JP2015527420 A JP 2015527420A JP 2015527420 A JP2015527420 A JP 2015527420A JP 2015526725 A5 JP2015526725 A5 JP 2015526725A5
- Authority
- JP
- Japan
- Prior art keywords
- ntprocnp
- pregnancy
- time point
- subject
- related vascular
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
- 239000012530 fluid Substances 0.000 claims description 7
- 230000035935 pregnancy Effects 0.000 claims 28
- 238000000034 method Methods 0.000 claims 23
- 208000019553 vascular disease Diseases 0.000 claims 14
- 239000012472 biological sample Substances 0.000 claims 10
- 239000000523 sample Substances 0.000 claims 6
- 102000012421 C-Type Natriuretic Peptide Human genes 0.000 claims 5
- 101800000060 C-type natriuretic peptide Proteins 0.000 claims 5
- 206010059245 Angiopathy Diseases 0.000 claims 3
- 239000011230 binding agent Substances 0.000 claims 3
- 210000001124 body fluid Anatomy 0.000 claims 3
- 230000002411 adverse Effects 0.000 claims 2
- 230000004578 fetal growth Effects 0.000 claims 2
- 238000012544 monitoring process Methods 0.000 claims 2
- 201000011461 pre-eclampsia Diseases 0.000 claims 2
- 230000036266 weeks of gestation Effects 0.000 claims 2
- 208000009206 Abruptio Placentae Diseases 0.000 claims 1
- 206010070538 Gestational hypertension Diseases 0.000 claims 1
- 201000005624 HELLP Syndrome Diseases 0.000 claims 1
- 206010018981 Haemorrhage in pregnancy Diseases 0.000 claims 1
- 206010020772 Hypertension Diseases 0.000 claims 1
- 208000016622 Umbilical cord vascular disease Diseases 0.000 claims 1
- 208000024248 Vascular System injury Diseases 0.000 claims 1
- 208000012339 Vascular injury Diseases 0.000 claims 1
- 210000004381 amniotic fluid Anatomy 0.000 claims 1
- 239000010839 body fluid Substances 0.000 claims 1
- 210000001175 cerebrospinal fluid Anatomy 0.000 claims 1
- 210000003756 cervix mucus Anatomy 0.000 claims 1
- 239000003795 chemical substances by application Substances 0.000 claims 1
- 231100000562 fetal loss Toxicity 0.000 claims 1
- 208000037824 growth disorder Diseases 0.000 claims 1
- 201000001421 hyperglycemia Diseases 0.000 claims 1
- 238000000338 in vitro Methods 0.000 claims 1
- 210000004880 lymph fluid Anatomy 0.000 claims 1
- 238000005259 measurement Methods 0.000 claims 1
- 201000008532 placental abruption Diseases 0.000 claims 1
- 230000003169 placental effect Effects 0.000 claims 1
- 210000002381 plasma Anatomy 0.000 claims 1
- 230000036470 plasma concentration Effects 0.000 claims 1
- 238000011084 recovery Methods 0.000 claims 1
- 210000000582 semen Anatomy 0.000 claims 1
- 210000002966 serum Anatomy 0.000 claims 1
- 210000001179 synovial fluid Anatomy 0.000 claims 1
- 210000002700 urine Anatomy 0.000 claims 1
- 108010070573 NTproCNP Proteins 0.000 description 1
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201261682729P | 2012-08-13 | 2012-08-13 | |
| US61/682,729 | 2012-08-13 | ||
| PCT/NZ2013/000142 WO2014027899A1 (en) | 2012-08-13 | 2013-08-13 | NT-proCNP AS A BIOMARKER OF VASCULAR DISORDERS AND PREGNANCY COMPLICATION |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2015526725A JP2015526725A (ja) | 2015-09-10 |
| JP2015526725A5 true JP2015526725A5 (https=) | 2018-07-05 |
| JP6423788B2 JP6423788B2 (ja) | 2018-11-14 |
Family
ID=50101335
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2015527420A Expired - Fee Related JP6423788B2 (ja) | 2012-08-13 | 2013-08-13 | 血管障害及び妊娠合併症のバイオマーカーとしてのＮＴ−ｐｒｏＣＮＰ |
Country Status (9)
| Country | Link |
|---|---|
| US (1) | US10012656B2 (https=) |
| EP (1) | EP2883060B1 (https=) |
| JP (1) | JP6423788B2 (https=) |
| CN (1) | CN104937420B (https=) |
| AU (1) | AU2013303302B2 (https=) |
| CA (1) | CA2882116A1 (https=) |
| IN (1) | IN2015KN00571A (https=) |
| SG (2) | SG11201501145SA (https=) |
| WO (1) | WO2014027899A1 (https=) |
Families Citing this family (8)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US10039813B2 (en) | 2012-02-07 | 2018-08-07 | Massachusetts Institute Of Technology | Use of antagonists of ghrelin or ghrelin receptor to prevent or treat stress-sensitive psychiatric illness |
| JP6423788B2 (ja) * | 2012-08-13 | 2018-11-14 | オタゴ イノベーション リミテッド | 血管障害及び妊娠合併症のバイオマーカーとしてのＮＴ−ｐｒｏＣＮＰ |
| WO2014144231A1 (en) | 2013-03-15 | 2014-09-18 | Massachusetts Institute Of Technology | Use of antagonists of growth hormone or growth hormone receptor to prevent or treat stress-sensitive psychiatric illness |
| WO2016064815A1 (en) * | 2014-10-20 | 2016-04-28 | Massachusetts Institute Of Technology | Functional ghrelin receptor antagonism during pregnancy to prevent stress-associated mental illness in offspring and mothers |
| WO2016138099A1 (en) | 2015-02-24 | 2016-09-01 | Massachusetts Institute Of Technology | Use of ghrelin or functional ghrelin receptor agonists to prevent and treat stress-sensitive psychiatric illness |
| TWI776812B (zh) * | 2016-06-02 | 2022-09-11 | 荷蘭商菲林公司 | 血管收縮素-1-受體拮抗劑 |
| WO2018216580A1 (ja) * | 2017-05-22 | 2018-11-29 | 東ソー株式会社 | アドレノメデュリン濃度変動による予後予測の情報提供方法及びその試薬 |
| WO2019199869A1 (en) * | 2018-04-10 | 2019-10-17 | Quanterix Corporation | Quantification of biomarkers present in physiological samples |
Family Cites Families (8)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| AT407580B (de) * | 1999-08-20 | 2001-04-25 | Biomedica Gmbh | Indikatorpeptid zur diagnose und/oder vorhersage von cardiovasculären und/oder endothelialen erkrankungen, antikörperzusammensetzung und immunoassay |
| WO2004099139A1 (en) | 2000-09-15 | 2004-11-18 | Baylor University | Indole-containing compounds with anti-tubulin and vascular targeting activity |
| DK1644740T3 (da) * | 2003-06-17 | 2011-02-21 | Otago Innovation Ltd | Vurdering af skeletal vækst ved anvendelse af målinger af NT-CNP-peptider |
| DE10338733A1 (de) | 2003-08-22 | 2005-03-24 | Berdel, Wolfgang E., Prof. Dr.med. | Fusionspolypeptide und deren Verwendung für die antivaskuläre Tumortherapie |
| US20100041989A1 (en) | 2006-09-29 | 2010-02-18 | The Trustees Of The University Of Pennsylvania | Use of ultrasound as an antivascular agent |
| CN103109192A (zh) * | 2010-06-18 | 2013-05-15 | 塞尚公司 | 用于妊娠性高血压和先兆子痫的预后和风险评估的标志物 |
| US20150293119A1 (en) | 2011-12-23 | 2015-10-15 | Mayo Foundation For Medical Education And Research | Assessing renal structural alterations and outcomes |
| JP6423788B2 (ja) * | 2012-08-13 | 2018-11-14 | オタゴ イノベーション リミテッド | 血管障害及び妊娠合併症のバイオマーカーとしてのＮＴ−ｐｒｏＣＮＰ |
-
2013
- 2013-08-13 JP JP2015527420A patent/JP6423788B2/ja not_active Expired - Fee Related
- 2013-08-13 IN IN571KON2015 patent/IN2015KN00571A/en unknown
- 2013-08-13 SG SG11201501145SA patent/SG11201501145SA/en unknown
- 2013-08-13 CN CN201380053106.1A patent/CN104937420B/zh not_active Expired - Fee Related
- 2013-08-13 EP EP13829360.0A patent/EP2883060B1/en not_active Not-in-force
- 2013-08-13 US US14/421,423 patent/US10012656B2/en not_active Expired - Fee Related
- 2013-08-13 AU AU2013303302A patent/AU2013303302B2/en not_active Ceased
- 2013-08-13 SG SG10201700872TA patent/SG10201700872TA/en unknown
- 2013-08-13 CA CA2882116A patent/CA2882116A1/en not_active Abandoned
- 2013-08-13 WO PCT/NZ2013/000142 patent/WO2014027899A1/en not_active Ceased
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| JP2015526725A5 (https=) | ||
| Staff et al. | Circulating concentrations of sFlt1 (soluble fms-like tyrosine kinase 1) in fetal and maternal serum during pre-eclampsia | |
| Lawson et al. | A pregnancy detection assay using milk samples: Evaluation and considerations | |
| Anderson et al. | Biochemical markers to predict preeclampsia | |
| Schrey-Petersen et al. | Anti-angiogenesis and Preeclampsia in 2016 | |
| Chen et al. | Serum levels of GDF15 are reduced in preeclampsia and the reduction is more profound in late-onset than early-onset cases | |
| Kim et al. | The relationship of the level of circulating antiangiogenic factors to the clinical manifestations of preeclampsia | |
| Masuyama et al. | Superimposed preeclampsia in women with chronic kidney disease | |
| JP2015038512A5 (https=) | ||
| Bálint et al. | Pregnancy does not affect fecal calprotectin concentration in healthy women | |
| JP2013532129A5 (https=) | ||
| JP2015531873A5 (https=) | ||
| Chehroudi et al. | Dysregulation of inflammatory cytokines and inhibition of VEGFA in the human umbilical cord are associated with negative pregnancy outcomes | |
| Tokalioglu et al. | Comparison of VEGF-A levels in women with threatened abortion, early pregnancy loss and uncomplicated healthy pregnancies | |
| Singh et al. | Does microalbuminuria at mid‐pregnancy predict development of subsequent pre‐eclampsia? | |
| Chen et al. | Levels of placental extracellular vesicles predicts fetal growth restriction and fetal distress in established severe pre‐eclampsia | |
| Yung et al. | Death associated protein kinase 1 (DAPK-1) is increased in preeclampsia | |
| Pakniat et al. | The prediction of Preeclampsia and its association with hemoglobin and hematocrit in the first trimester of pregnancy | |
| Atalay et al. | The effect of magnesium sulfate treatment on serum cardiac troponin I levels in preeclamptic women | |
| US20140127703A1 (en) | Method for Diagnosing Preeclampsia | |
| Hamed et al. | Evaluation of changes in renal function of pregnant women with preeclampsia in Al-jabal Al-akhdar | |
| von Dadelszen et al. | Activated protein C as disease-modifying therapy in antenatal preeclampsia: An open-label, single arm safety and efficacy trial | |
| Toda et al. | Correlates of NT‐proBNP concentration in patients with essential hypertension in absence of congestive heart failure | |
| ER et al. | The use of maternal delta neutrophil index for the prediction of chorioamnionitis in very early preterm premature rupture of membranes | |
| RU2442166C1 (ru) | Способ прогнозирования формирования фетоплацентарной недостаточности у больных с угрожающим выкидышем в первом триместре беременности |