JP2015526435A - 抗体成分と血液脳関門を通過するポリペプチドと細胞毒とを含むコンジュゲート - Google Patents

抗体成分と血液脳関門を通過するポリペプチドと細胞毒とを含むコンジュゲート Download PDF

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JP2015526435A
JP2015526435A JP2015526846A JP2015526846A JP2015526435A JP 2015526435 A JP2015526435 A JP 2015526435A JP 2015526846 A JP2015526846 A JP 2015526846A JP 2015526846 A JP2015526846 A JP 2015526846A JP 2015526435 A JP2015526435 A JP 2015526435A
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polypeptide
conjugate
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antibody
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カステーニュ，ジャン−ポール
ヤン，ガオチアン
シュ，クリスチャン
デミュール，ミシェル
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アンジオケム インコーポレーテッド
アンジオケム インコーポレーテッド
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JP2015526846A 2012-08-14 2013-08-14 抗体成分と血液脳関門を通過するポリペプチドと細胞毒とを含むコンジュゲート Pending JP2015526435A (ja)

Applications Claiming Priority (5)

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US201261682991P 2012-08-14 2012-08-14
US61/682,991 2012-08-14
US201361865071P 2013-08-12 2013-08-12
US61/865,071 2013-08-12
PCT/CA2013/050625 WO2014026286A1 (en) 2012-08-14 2013-08-14 Conjugates including an antibody moiety, a polypeptide that traverses the blood-brain barrier, and a cytotoxin

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JP2015526435A true JP2015526435A (ja) 2015-09-10
JP2015526435A5 JP2015526435A5 (https=) 2016-03-31

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US (2) US20160106856A1 (https=)
EP (1) EP2885321A4 (https=)
JP (1) JP2015526435A (https=)
CN (1) CN104781281A (https=)
AU (1) AU2013302273A1 (https=)
CA (1) CA2880342A1 (https=)
WO (1) WO2014026286A1 (https=)

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CA2740316A1 (en) 2008-10-15 2010-04-22 Angiochem Inc. Conjugates of glp-1 agonists and uses thereof
CA2745524C (en) 2008-12-05 2020-06-09 Angiochem Inc. Conjugates of neurotensin or neurotensin analogs and uses thereof
JP2015526434A (ja) 2012-08-14 2015-09-10 アンジオケム インコーポレーテッド ペプチド−デンドリマーコンジュゲート及びその使用
HUE047952T2 (hu) 2014-04-25 2020-05-28 Pf Medicament Ellenanyag-drog konjugátum és alkalmazása rák kezelésében történõ alkalmazásra
HRP20190888T8 (hr) 2014-04-25 2019-10-04 Pierre Fabre Médicament Konjugat antitijela za igf-1r i lijeka i njegova upotreba u liječenju karcinoma
EP3218414A1 (en) * 2014-11-14 2017-09-20 Angiochem Inc. Conjugates including an antibody moiety, a polypeptide that traverses the blood-brain barrier, and a cytotoxin
EP3307326B9 (en) 2015-06-15 2021-02-24 Angiochem Inc. Methods for the treatment of leptomeningeal carcinomatosis
EP3777894A4 (en) * 2018-03-30 2022-04-06 Hanmi Pharm. Co., Ltd. ANTI-BRAIN DIRECTIONAL LONG-ACTING PROTEIN CONJUGATE, METHOD OF MANUFACTURE THEREOF AND COMPOSITION THEREOF
WO2020069488A1 (en) * 2018-09-28 2020-04-02 North Carolina State University Compositions and methods for drug delivery
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