JP2015504909A5 - - Google Patents
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- Publication number
- JP2015504909A5 JP2015504909A5 JP2014553715A JP2014553715A JP2015504909A5 JP 2015504909 A5 JP2015504909 A5 JP 2015504909A5 JP 2014553715 A JP2014553715 A JP 2014553715A JP 2014553715 A JP2014553715 A JP 2014553715A JP 2015504909 A5 JP2015504909 A5 JP 2015504909A5
- Authority
- JP
- Japan
- Prior art keywords
- methyl
- sulfane
- galactopyranosyl
- bis
- benzopyran
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| EP12152413.6 | 2012-01-25 | ||
| EP12152413.6A EP2620443A1 (en) | 2012-01-25 | 2012-01-25 | Novel galactoside inhibitors of galectins |
| PCT/EP2013/051339 WO2013110704A1 (en) | 2012-01-25 | 2013-01-24 | Novel galactoside inhibitors of galectins |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2015504909A JP2015504909A (ja) | 2015-02-16 |
| JP2015504909A5 true JP2015504909A5 (cg-RX-API-DMAC7.html) | 2016-03-10 |
| JP6158840B2 JP6158840B2 (ja) | 2017-07-05 |
Family
ID=47598867
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2014553715A Expired - Fee Related JP6158840B2 (ja) | 2012-01-25 | 2013-01-24 | ガレクチンのガラクトシド阻害剤 |
Country Status (8)
| Country | Link |
|---|---|
| US (1) | US9353141B2 (cg-RX-API-DMAC7.html) |
| EP (2) | EP2620443A1 (cg-RX-API-DMAC7.html) |
| JP (1) | JP6158840B2 (cg-RX-API-DMAC7.html) |
| CN (1) | CN104066743B (cg-RX-API-DMAC7.html) |
| CA (1) | CA2854986C (cg-RX-API-DMAC7.html) |
| ES (1) | ES2559857T3 (cg-RX-API-DMAC7.html) |
| IN (1) | IN2014DN05772A (cg-RX-API-DMAC7.html) |
| WO (1) | WO2013110704A1 (cg-RX-API-DMAC7.html) |
Families Citing this family (20)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| IL149139A0 (en) | 1999-11-03 | 2002-11-10 | Bristol Myers Squibb Co | Pharmaceutical compositions containing metformin and glyburide |
| US6586438B2 (en) | 1999-11-03 | 2003-07-01 | Bristol-Myers Squibb Co. | Antidiabetic formulation and method |
| US9243021B2 (en) | 2012-10-31 | 2016-01-26 | Galecto Biotech Ab | Galactoside inhibitor of galectins |
| JP6366598B2 (ja) * | 2012-11-15 | 2018-08-01 | タフツ ユニバーシティー | ガレクチンタンパク質阻害剤を用いて被験体の眼の血管新生または繊維症を処置し、調節し、または、予防する方法、組成物、およびキット |
| US12390486B2 (en) | 2012-12-20 | 2025-08-19 | Henry Ford Health System | Method for treating diastolic heart failure by inhibiting galectin-3 |
| US9907814B2 (en) | 2012-12-20 | 2018-03-06 | Henry Ford Health System | Method for treating diastolic heart failure by inhibiting galectin-3 |
| EP3415522A1 (en) * | 2014-07-09 | 2018-12-19 | Galecto Biotech AB | Novel hybrid galactoside inhibitor of galectins |
| US10774102B2 (en) * | 2015-01-30 | 2020-09-15 | Galecto Biotech Ab | Galactoside inhibitor of galectins |
| KR102346913B1 (ko) * | 2016-03-04 | 2022-01-04 | 갈랙틴 사이언시즈, 엘엘씨 | 갈렉틴과 관련된 질환의 예방 및 치료를 위한 셀레노갈락토시드 화합물 및 이의 용도 |
| WO2018011094A1 (en) * | 2016-07-12 | 2018-01-18 | Galecto Biotech Ab | Alpha-d-galactoside inhibitors of galectins |
| JP7038099B2 (ja) * | 2016-07-12 | 2022-03-17 | ガレクト バイオテック エービー | ガレクチンのα－Ｄ－ガラクトシド阻害剤 |
| JP7204676B2 (ja) | 2017-05-12 | 2023-01-16 | ガレクティン・サイエンシーズ・リミテッド・ライアビリティ・カンパニー | 疾患の予防および治療用の化合物およびその使用 |
| CA3085356A1 (en) | 2017-12-29 | 2019-07-04 | Glycomimetics, Inc. | Heterobifunctional inhibitors of e-selectin and galectin-3 |
| CN112672765A (zh) * | 2018-06-29 | 2021-04-16 | 格莱科斯生物医药公司 | 结合物 |
| WO2020139962A1 (en) | 2018-12-27 | 2020-07-02 | Glycomimetics, Inc. | Heterobifunctional inhibitors of e-selectin and galectin-3 |
| CN118373810A (zh) | 2018-12-27 | 2024-07-23 | 糖模拟物有限公司 | 抑制c-糖苷的半乳凝素-3 |
| WO2021028323A1 (en) * | 2019-08-09 | 2021-02-18 | Idorsia Pharmaceuticals Ltd | (2-acetamidyl)thio-beta-d-galactopyranoside derivatives |
| US20230038373A1 (en) | 2019-12-18 | 2023-02-09 | Glykos Biomedical Oy | Stabile conjugate |
| CN116270672A (zh) * | 2023-02-27 | 2023-06-23 | 江苏科技大学 | β-D-硫代葡萄糖钠盐在制备缓解或治疗急性肾损伤的药物中的应用 |
| CZ2023132A3 (cs) | 2023-04-04 | 2024-10-16 | Ústav Chemických Procesů Av Čr, V. V. I. | Komplexy ruthenia pro inhibici galektinů, způsob jejich výroby a jejich použití |
Family Cites Families (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| SE0100172D0 (sv) | 2001-01-22 | 2001-01-22 | Ulf Nilsson | New inhibitors against galectins |
| SE0401300D0 (sv) | 2004-05-21 | 2004-05-21 | Forskarpatent I Syd Ab | Novel Galactoside Inhibitors of Galectins |
| SE0401301D0 (sv) | 2004-05-21 | 2004-05-21 | Forskarpatent I Syd Ab | Novel 3-triazolyl-galactoside inhibitors of galectins |
| ES2611206T3 (es) | 2008-05-16 | 2017-05-05 | Galecto Biotech Ab | Derivados de di-(3-deoxi-3-1H-1,2,3-triazol-1-il)-beta-D-galacto-iranosil)sulfano como inhibidores de galectina-3 |
| WO2010126435A1 (en) | 2009-04-28 | 2010-11-04 | Forskarpatent I Syd Ab | Novel galactoside inhibitors of galectins |
| CA2884802A1 (en) | 2012-10-31 | 2014-05-08 | Galecto Biotech Ab | Galactoside inhibitor of galectin-3 and its use for treating pulmonary fibrosis |
-
2012
- 2012-01-25 EP EP12152413.6A patent/EP2620443A1/en not_active Withdrawn
-
2013
- 2013-01-24 JP JP2014553715A patent/JP6158840B2/ja not_active Expired - Fee Related
- 2013-01-24 IN IN5772DEN2014 patent/IN2014DN05772A/en unknown
- 2013-01-24 EP EP13700935.3A patent/EP2807176B1/en not_active Not-in-force
- 2013-01-24 WO PCT/EP2013/051339 patent/WO2013110704A1/en not_active Ceased
- 2013-01-24 CA CA2854986A patent/CA2854986C/en not_active Expired - Fee Related
- 2013-01-24 CN CN201380006432.7A patent/CN104066743B/zh not_active Expired - Fee Related
- 2013-01-24 US US14/364,169 patent/US9353141B2/en not_active Expired - Fee Related
- 2013-01-24 ES ES13700935.3T patent/ES2559857T3/es active Active