JP2015143218A5 - - Google Patents

Info

Publication number

JP2015143218A5

JP2015143218A5 JP2014264365A JP2014264365A JP2015143218A5 JP 2015143218 A5 JP2015143218 A5 JP 2015143218A5 JP 2014264365 A JP2014264365 A JP 2014264365A JP 2014264365 A JP2014264365 A JP 2014264365A JP 2015143218 A5 JP2015143218 A5 JP 2015143218A5

Authority

JP

Japan

Prior art keywords

solid preparation

water

mass

solid

less

Prior art date

2014-12-26

Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)

Granted

Links

• Espacenet
• Global Dossier
• Discuss

• 239000007787 solid Substances 0.000 claims 19
• 238000002360 preparation method Methods 0.000 claims 16
• 239000001913 cellulose Substances 0.000 claims 5
• 229920002678 cellulose Polymers 0.000 claims 5
• IBAQFPQHRJAVAV-ULAWRXDQSA-N Miglitol Chemical compound OCCN1C[C@H](O)[C@@H](O)[C@H](O)[C@H]1CO IBAQFPQHRJAVAV-ULAWRXDQSA-N 0.000 claims 3
• LFQSCWFLJHTTHZ-UHFFFAOYSA-N ethanol Chemical compound CCO LFQSCWFLJHTTHZ-UHFFFAOYSA-N 0.000 claims 3
• 238000009472 formulation Methods 0.000 claims 3
• 229960001110 miglitol Drugs 0.000 claims 3
• 239000000203 mixture Substances 0.000 claims 3
• CWSZBVAUYPTXTG-UHFFFAOYSA-N 5-[6-[[3,4-dihydroxy-6-(hydroxymethyl)-5-methoxyoxan-2-yl]oxymethyl]-3,4-dihydroxy-5-[4-hydroxy-3-(2-hydroxyethoxy)-6-(hydroxymethyl)-5-methoxyoxan-2-yl]oxyoxan-2-yl]oxy-6-(hydroxymethyl)-2-methyloxane-3,4-diol Chemical compound O1C(CO)C(OC)C(O)C(O)C1OCC1C(OC2C(C(O)C(OC)C(CO)O2)OCCO)C(O)C(O)C(OC2C(OC(C)C(O)C2O)CO)O1 CWSZBVAUYPTXTG-UHFFFAOYSA-N 0.000 claims 1
• FBPFZTCFMRRESA-FSIIMWSLSA-N D-Glucitol Natural products OC[C@H](O)[C@H](O)[C@@H](O)[C@H](O)CO FBPFZTCFMRRESA-FSIIMWSLSA-N 0.000 claims 1
• FBPFZTCFMRRESA-KAZBKCHUSA-N D-Mannitol Natural products OC[C@@H](O)[C@H](O)[C@H](O)[C@H](O)CO FBPFZTCFMRRESA-KAZBKCHUSA-N 0.000 claims 1
• UNXHWFMMPAWVPI-QWWZWVQMSA-N D-Threitol Natural products OC[C@@H](O)[C@H](O)CO UNXHWFMMPAWVPI-QWWZWVQMSA-N 0.000 claims 1
• FBPFZTCFMRRESA-JGWLITMVSA-N D-glucitol Chemical compound OC[C@H](O)[C@@H](O)[C@H](O)[C@H](O)CO FBPFZTCFMRRESA-JGWLITMVSA-N 0.000 claims 1
• 239000004386 Erythritol Substances 0.000 claims 1
• UNXHWFMMPAWVPI-ZXZARUISSA-N Erythritol Chemical compound OC[C@H](O)[C@H](O)CO UNXHWFMMPAWVPI-ZXZARUISSA-N 0.000 claims 1
• 229940009714 Erythritol Drugs 0.000 claims 1
• 239000004354 Hydroxyethyl cellulose Substances 0.000 claims 1
• 229920000663 Hydroxyethyl cellulose Polymers 0.000 claims 1
• 229920002153 Hydroxypropyl cellulose Polymers 0.000 claims 1
• GUBGYTABKSRVRQ-UUNJERMWSA-N Lactose Natural products O([C@@H]1[C@H](O)[C@H](O)[C@H](O)O[C@@H]1CO)[C@H]1[C@@H](O)[C@@H](O)[C@H](O)[C@H](CO)O1 GUBGYTABKSRVRQ-UUNJERMWSA-N 0.000 claims 1
• VQHSOMBJVWLPSR-WUJBLJFYSA-N Maltitol Chemical compound OC[C@H](O)[C@@H](O)[C@@H]([C@H](O)CO)O[C@H]1O[C@H](CO)[C@@H](O)[C@H](O)[C@H]1O VQHSOMBJVWLPSR-WUJBLJFYSA-N 0.000 claims 1
• FBPFZTCFMRRESA-KVTDHHQDSA-N Mannitol Chemical compound OC[C@@H](O)[C@@H](O)[C@H](O)[C@H](O)CO FBPFZTCFMRRESA-KVTDHHQDSA-N 0.000 claims 1
• WHNWPMSKXPGLAX-UHFFFAOYSA-N N-Vinylpyrrolidone Chemical compound C=CN1CCCC1=O WHNWPMSKXPGLAX-UHFFFAOYSA-N 0.000 claims 1
• XAPRFLSJBSXESP-UHFFFAOYSA-N Oxycinchophen Chemical compound N=1C2=CC=CC=C2C(C(=O)O)=C(O)C=1C1=CC=CC=C1 XAPRFLSJBSXESP-UHFFFAOYSA-N 0.000 claims 1
• 229940069328 Povidone Drugs 0.000 claims 1
• 239000004373 Pullulan Substances 0.000 claims 1
• 229920001218 Pullulan Polymers 0.000 claims 1
• HDTRYLNUVZCQOY-LIZSDCNHSA-N Trehalose Chemical compound O[C@@H]1[C@@H](O)[C@H](O)[C@@H](CO)O[C@@H]1O[C@@H]1[C@H](O)[C@@H](O)[C@H](O)[C@@H](CO)O1 HDTRYLNUVZCQOY-LIZSDCNHSA-N 0.000 claims 1
• HDTRYLNUVZCQOY-WSWWMNSNSA-N Trehalose Natural products O[C@@H]1[C@@H](O)[C@@H](O)[C@@H](CO)O[C@@H]1O[C@@H]1[C@H](O)[C@@H](O)[C@@H](O)[C@@H](CO)O1 HDTRYLNUVZCQOY-WSWWMNSNSA-N 0.000 claims 1
• HEBKCHPVOIAQTA-SCDXWVJYSA-N Xylitol Chemical compound OC[C@H](O)[C@@H](O)[C@H](O)CO HEBKCHPVOIAQTA-SCDXWVJYSA-N 0.000 claims 1
• 229960002675 Xylitol Drugs 0.000 claims 1
• 235000019414 erythritol Nutrition 0.000 claims 1
• 235000019447 hydroxyethyl cellulose Nutrition 0.000 claims 1
• 239000001863 hydroxypropyl cellulose Substances 0.000 claims 1
• 235000010977 hydroxypropyl cellulose Nutrition 0.000 claims 1
• 239000001866 hydroxypropyl methyl cellulose Substances 0.000 claims 1
• 229920003088 hydroxypropyl methyl cellulose Polymers 0.000 claims 1
• 235000010979 hydroxypropyl methyl cellulose Nutrition 0.000 claims 1
• 229960003943 hypromellose Drugs 0.000 claims 1
• GUBGYTABKSRVRQ-XLOQQCSPSA-N lactose Chemical compound O[C@@H]1[C@@H](O)[C@@H](O)[C@@H](CO)O[C@H]1O[C@@H]1[C@@H](CO)O[C@H](O)[C@H](O)[C@H]1O GUBGYTABKSRVRQ-XLOQQCSPSA-N 0.000 claims 1
• 239000008101 lactose Substances 0.000 claims 1
• 239000000845 maltitol Substances 0.000 claims 1
• 235000010449 maltitol Nutrition 0.000 claims 1
• 229940035436 maltitol Drugs 0.000 claims 1
• 235000010355 mannitol Nutrition 0.000 claims 1
• 229920000609 methyl cellulose Polymers 0.000 claims 1
• 239000001923 methylcellulose Substances 0.000 claims 1
• 235000010981 methylcellulose Nutrition 0.000 claims 1
• 229920000036 polyvinylpyrrolidone Polymers 0.000 claims 1
• 235000013855 polyvinylpyrrolidone Nutrition 0.000 claims 1
• 235000019423 pullulan Nutrition 0.000 claims 1
• 239000000600 sorbitol Substances 0.000 claims 1
• 229960002920 sorbitol Drugs 0.000 claims 1
• 235000010356 sorbitol Nutrition 0.000 claims 1
• 229920003169 water-soluble polymer Polymers 0.000 claims 1
• 239000000811 xylitol Substances 0.000 claims 1
• 235000010447 xylitol Nutrition 0.000 claims 1