JP2015096544A5 - - Google Patents
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- Publication number
- JP2015096544A5 JP2015096544A5 JP2015000566A JP2015000566A JP2015096544A5 JP 2015096544 A5 JP2015096544 A5 JP 2015096544A5 JP 2015000566 A JP2015000566 A JP 2015000566A JP 2015000566 A JP2015000566 A JP 2015000566A JP 2015096544 A5 JP2015096544 A5 JP 2015096544A5
- Authority
- JP
- Japan
- Prior art keywords
- tumor
- group
- medicament
- compound
- ratios
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| DE102007047738.6 | 2007-10-05 | ||
| DE102007047738A DE102007047738A1 (de) | 2007-10-05 | 2007-10-05 | Imidazolderivate |
Related Parent Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2010527344A Division JP5725860B2 (ja) | 2007-10-05 | 2008-09-09 | イミダゾール誘導体 |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2015096544A JP2015096544A (ja) | 2015-05-21 |
| JP2015096544A5 true JP2015096544A5 (enExample) | 2015-07-30 |
| JP5997782B2 JP5997782B2 (ja) | 2016-09-28 |
Family
ID=40151186
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2010527344A Expired - Fee Related JP5725860B2 (ja) | 2007-10-05 | 2008-09-09 | イミダゾール誘導体 |
| JP2015000566A Expired - Fee Related JP5997782B2 (ja) | 2007-10-05 | 2015-01-05 | イミダゾール誘導体 |
Family Applications Before (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2010527344A Expired - Fee Related JP5725860B2 (ja) | 2007-10-05 | 2008-09-09 | イミダゾール誘導体 |
Country Status (16)
| Country | Link |
|---|---|
| US (1) | US20100249132A1 (enExample) |
| EP (1) | EP2193122B1 (enExample) |
| JP (2) | JP5725860B2 (enExample) |
| KR (1) | KR20100075602A (enExample) |
| CN (1) | CN101809001B (enExample) |
| AR (1) | AR068659A1 (enExample) |
| AU (1) | AU2008310117B2 (enExample) |
| BR (1) | BRPI0817609A2 (enExample) |
| CA (1) | CA2701568C (enExample) |
| DE (1) | DE102007047738A1 (enExample) |
| EA (1) | EA201000558A1 (enExample) |
| ES (1) | ES2601139T3 (enExample) |
| IL (1) | IL204683A (enExample) |
| MX (1) | MX2010003368A (enExample) |
| WO (1) | WO2009046804A1 (enExample) |
| ZA (1) | ZA201003125B (enExample) |
Families Citing this family (20)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE102009049211A1 (de) * | 2009-10-13 | 2011-04-28 | Merck Patent Gmbh | Sulfoxide |
| AU2012212323A1 (en) | 2011-02-01 | 2013-09-12 | The Board Of Trustees Of The University Of Illinois | HDAC inhibitors and therapeutic methods using the same |
| TW201309698A (zh) | 2011-03-18 | 2013-03-01 | Ono Pharmaceutical Co | 四氫咔啉衍生物 |
| JP6158817B2 (ja) * | 2011-10-28 | 2017-07-05 | インヒビタクシン リミテッド | 治療に有用なピリダジン誘導体 |
| US9409895B2 (en) | 2012-12-19 | 2016-08-09 | Novartis Ag | Autotaxin inhibitors |
| ES2715682T3 (es) | 2012-12-19 | 2019-06-05 | Novartis Ag | Inhibidores de la autotaxina |
| MX368059B (es) | 2013-07-18 | 2019-09-18 | Novartis Ag | Inhibidores de autotaxina que comprenden un núcleo de anillo heteroaromático de bencil-amida cíclica. |
| EP3022201A1 (en) * | 2013-07-18 | 2016-05-25 | Novartis AG | Autotaxin inhibitors |
| EP3878848A1 (en) | 2013-11-22 | 2021-09-15 | Sabre Therapeutics LLC | Autotaxin inhibiting indole compounds |
| US9051320B1 (en) | 2014-08-18 | 2015-06-09 | Pharmakea, Inc. | Methods for the treatment of metabolic disorders by a selective small molecule autotaxin inhibitor |
| CN107074822B (zh) * | 2014-09-15 | 2020-01-03 | 爱杜西亚药品有限公司 | 作为t型钙通道阻断剂的三唑化合物 |
| GB201501870D0 (en) | 2015-02-04 | 2015-03-18 | Cancer Rec Tech Ltd | Autotaxin inhibitors |
| GB201502020D0 (en) | 2015-02-06 | 2015-03-25 | Cancer Rec Tech Ltd | Autotaxin inhibitory compounds |
| EP4026549A1 (en) | 2015-05-27 | 2022-07-13 | Sabre Therapeutics LLC | Autotaxin inhibitors and uses thereof |
| HK1252425A1 (zh) | 2015-06-05 | 2019-05-24 | Vertex Pharmaceuticals Incorporated | 用於治疗脱髓鞘疾病的三唑类药物 |
| WO2018106646A1 (en) | 2016-12-06 | 2018-06-14 | Vertex Pharmaceuticals Incorporated | Aminotriazoles for the treatment of demyelinating diseases |
| WO2018106641A1 (en) | 2016-12-06 | 2018-06-14 | Vertex Pharmaceuticals Incorporated | Pyrazoles for the treatment of demyelinating diseases |
| WO2018106643A1 (en) | 2016-12-06 | 2018-06-14 | Vertex Pharmaceuticals Incorporated | Heterocyclic azoles for the treatment of demyelinating diseases |
| US20230277490A1 (en) * | 2020-07-31 | 2023-09-07 | Cedars-Sinai Medical Center | Glutamine as an anticancer therapy in solid tumors |
| EP4197596A1 (en) | 2021-12-15 | 2023-06-21 | Eberhard Karls Universität Tübingen Medizinische Fakultät | Imidazole derivatives for the treatment and prophylaxis of infectious diseases |
Family Cites Families (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5747469A (en) | 1991-03-06 | 1998-05-05 | Board Of Regents, The University Of Texas System | Methods and compositions comprising DNA damaging agents and p53 |
| GB9904387D0 (en) | 1999-02-25 | 1999-04-21 | Pharmacia & Upjohn Spa | Antitumour synergistic composition |
| EP1187633A4 (en) | 1999-04-08 | 2005-05-11 | Arch Dev Corp | USE OF ANTI-VEGF ANTIBODIES TO ENHANCE RADIATION IN ANTICANCER THERAPY |
| DE19954707A1 (de) * | 1999-11-13 | 2001-05-17 | Merck Patent Gmbh | Imidazolverbindungen als Phosphodiesterase VII-Hemmer |
| ATE420878T1 (de) * | 2000-02-18 | 2009-01-15 | Kyowa Hakko Kirin Co Ltd | Isoxazol- und thiazolverbindungen und ihre verwendung als medikamente |
| FR2889190A1 (fr) * | 2005-08-01 | 2007-02-02 | Merck Sante Soc Par Actions Si | Nouveaux derives d'imidazoles carboxamides comme inhibiteurs de fructose -1,6-biphosphatase et compositions pharmaceutiques les contenant |
-
2007
- 2007-10-05 DE DE102007047738A patent/DE102007047738A1/de not_active Withdrawn
-
2008
- 2008-09-09 ES ES08801940.1T patent/ES2601139T3/es active Active
- 2008-09-09 KR KR1020107009777A patent/KR20100075602A/ko not_active Withdrawn
- 2008-09-09 JP JP2010527344A patent/JP5725860B2/ja not_active Expired - Fee Related
- 2008-09-09 WO PCT/EP2008/007367 patent/WO2009046804A1/de not_active Ceased
- 2008-09-09 CN CN2008801089528A patent/CN101809001B/zh not_active Expired - Fee Related
- 2008-09-09 US US12/681,380 patent/US20100249132A1/en not_active Abandoned
- 2008-09-09 CA CA2701568A patent/CA2701568C/en not_active Expired - Fee Related
- 2008-09-09 MX MX2010003368A patent/MX2010003368A/es not_active Application Discontinuation
- 2008-09-09 AU AU2008310117A patent/AU2008310117B2/en not_active Ceased
- 2008-09-09 EA EA201000558A patent/EA201000558A1/ru unknown
- 2008-09-09 EP EP08801940.1A patent/EP2193122B1/de not_active Not-in-force
- 2008-09-09 BR BRPI0817609 patent/BRPI0817609A2/pt not_active IP Right Cessation
- 2008-10-03 AR ARP080104330A patent/AR068659A1/es unknown
-
2010
- 2010-03-23 IL IL204683A patent/IL204683A/en not_active IP Right Cessation
- 2010-05-04 ZA ZA2010/03125A patent/ZA201003125B/en unknown
-
2015
- 2015-01-05 JP JP2015000566A patent/JP5997782B2/ja not_active Expired - Fee Related
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