JP2014533495A - 第ｖｉｉｉ因子の生産のための方法 - Google Patents
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- VBEQCZHXXJYVRD-GACYYNSASA-N uroanthelone Chemical compound C([C@@H](C(=O)N[C@H](C(=O)N[C@@H](CS)C(=O)N[C@@H](CC(N)=O)C(=O)N[C@@H](CS)C(=O)N[C@H](C(=O)N[C@@H]([C@@H](C)CC)C(=O)NCC(=O)N[C@@H](CC=1C=CC(O)=CC=1)C(=O)N[C@@H](CO)C(=O)NCC(=O)N[C@@H](CC(O)=O)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](CS)C(=O)N[C@@H](CCC(N)=O)C(=O)N[C@@H]([C@@H](C)O)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](CC(O)=O)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](CC=1C2=CC=CC=C2NC=1)C(=O)N[C@@H](CC=1C2=CC=CC=C2NC=1)C(=O)N[C@@H](CCC(O)=O)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CCCNC(N)=N)C(O)=O)C(C)C)[C@@H](C)O)NC(=O)[C@H](CO)NC(=O)[C@H](CC(O)=O)NC(=O)[C@H](CC(C)C)NC(=O)[C@H](CO)NC(=O)[C@H](CCC(O)=O)NC(=O)[C@@H](NC(=O)[C@H](CC=1NC=NC=1)NC(=O)[C@H](CCSC)NC(=O)[C@H](CS)NC(=O)[C@@H](NC(=O)CNC(=O)CNC(=O)[C@H](CC(N)=O)NC(=O)[C@H](CC(C)C)NC(=O)[C@H](CS)NC(=O)[C@H](CC=1C=CC(O)=CC=1)NC(=O)CNC(=O)[C@H](CC(O)=O)NC(=O)[C@H](CC=1C=CC(O)=CC=1)NC(=O)[C@H](CO)NC(=O)[C@H](CO)NC(=O)[C@H]1N(CCC1)C(=O)[C@H](CS)NC(=O)CNC(=O)[C@H]1N(CCC1)C(=O)[C@H](CC=1C=CC(O)=CC=1)NC(=O)[C@H](CO)NC(=O)[C@@H](N)CC(N)=O)C(C)C)[C@@H](C)CC)C1=CC=C(O)C=C1 VBEQCZHXXJYVRD-GACYYNSASA-N 0.000 description 1
- 230000009385 viral infection Effects 0.000 description 1
- 239000013603 viral vector Substances 0.000 description 1
- 239000011782 vitamin Substances 0.000 description 1
- 235000013343 vitamin Nutrition 0.000 description 1
- 229940088594 vitamin Drugs 0.000 description 1
- 229930003231 vitamin Natural products 0.000 description 1
- 238000005406 washing Methods 0.000 description 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/745—Blood coagulation or fibrinolysis factors
- C07K14/755—Factors VIII, e.g. factor VIII C (AHF), factor VIII Ag (VWF)
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- Biophysics (AREA)
- Medicinal Chemistry (AREA)
- Zoology (AREA)
- Biochemistry (AREA)
- Toxicology (AREA)
- General Health & Medical Sciences (AREA)
- Genetics & Genomics (AREA)
- Gastroenterology & Hepatology (AREA)
- Molecular Biology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Hematology (AREA)
- Peptides Or Proteins (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
Applications Claiming Priority (5)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| EP11189861.5 | 2011-11-21 | ||
| EP11189861 | 2011-11-21 | ||
| US201161563188P | 2011-11-23 | 2011-11-23 | |
| US61/563,188 | 2011-11-23 | ||
| PCT/EP2012/071701 WO2013075926A1 (en) | 2011-11-21 | 2012-11-02 | Method for production of factor viii |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2014533495A true JP2014533495A (ja) | 2014-12-15 |
| JP2014533495A5 JP2014533495A5 (https=) | 2015-12-24 |
Family
ID=48469150
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2014541599A Withdrawn JP2014533495A (ja) | 2011-11-21 | 2012-11-02 | 第ｖｉｉｉ因子の生産のための方法 |
Country Status (5)
| Country | Link |
|---|---|
| US (1) | US20140308707A1 (https=) |
| EP (1) | EP2782929A1 (https=) |
| JP (1) | JP2014533495A (https=) |
| CN (1) | CN103946235A (https=) |
| WO (1) | WO2013075926A1 (https=) |
Families Citing this family (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2017118764A1 (en) * | 2016-01-07 | 2017-07-13 | Thomas Brocker | Novel approaches for the in vivo and in vitro visualization of dying cells |
| CN106167527A (zh) * | 2016-06-13 | 2016-11-30 | 长沙郝怡雅医药科技有限公司 | 一种融合蛋白 |
Family Cites Families (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US20060099685A1 (en) * | 1999-04-15 | 2006-05-11 | Yallop Christopher A | Recombinant expression of factor VIII in human cells |
| AU2003237870A1 (en) * | 2002-06-07 | 2003-12-22 | The Brigham & Women's Hospital, Inc. | Method and composition for inhibing or slowing blood coagulation |
| WO2007124106A2 (en) * | 2006-04-21 | 2007-11-01 | Bayer Healthcare Llc | Application of antl-apoptotic genes in mammalian cells for perfusion culture. |
| EP1988101A1 (en) * | 2007-05-04 | 2008-11-05 | Novo Nordisk A/S | Improvement of factor VIII polypeptide titers in cell cultures |
-
2012
- 2012-11-02 WO PCT/EP2012/071701 patent/WO2013075926A1/en not_active Ceased
- 2012-11-02 US US14/358,886 patent/US20140308707A1/en not_active Abandoned
- 2012-11-02 CN CN201280057127.6A patent/CN103946235A/zh not_active Withdrawn
- 2012-11-02 EP EP12779084.8A patent/EP2782929A1/en not_active Withdrawn
- 2012-11-02 JP JP2014541599A patent/JP2014533495A/ja not_active Withdrawn
Also Published As
| Publication number | Publication date |
|---|---|
| EP2782929A1 (en) | 2014-10-01 |
| US20140308707A1 (en) | 2014-10-16 |
| WO2013075926A1 (en) | 2013-05-30 |
| CN103946235A (zh) | 2014-07-23 |
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