JP2014533102A5 - - Google Patents
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- Publication number
- JP2014533102A5 JP2014533102A5 JP2014539995A JP2014539995A JP2014533102A5 JP 2014533102 A5 JP2014533102 A5 JP 2014533102A5 JP 2014539995 A JP2014539995 A JP 2014539995A JP 2014539995 A JP2014539995 A JP 2014539995A JP 2014533102 A5 JP2014533102 A5 JP 2014533102A5
- Authority
- JP
- Japan
- Prior art keywords
- clonotype
- segment
- patient
- pharmaceutical composition
- group
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
Applications Claiming Priority (5)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201161556125P | 2011-11-04 | 2011-11-04 | |
| US61/556,125 | 2011-11-04 | ||
| US201161561234P | 2011-11-17 | 2011-11-17 | |
| US61/561,234 | 2011-11-17 | ||
| PCT/US2012/061977 WO2013066726A1 (en) | 2011-11-04 | 2012-10-25 | T-cell receptor clonotypes shared among ankylosing spondylitis patients |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2014533102A JP2014533102A (ja) | 2014-12-11 |
| JP2014533102A5 true JP2014533102A5 (cg-RX-API-DMAC7.html) | 2015-12-10 |
| JP6130387B2 JP6130387B2 (ja) | 2017-05-17 |
Family
ID=48192637
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2014539995A Active JP6130387B2 (ja) | 2011-11-04 | 2012-10-25 | 強直性脊椎炎の患者間で共有されるｔ細胞受容体クロノタイプ |
Country Status (5)
| Country | Link |
|---|---|
| US (2) | US20150252422A1 (cg-RX-API-DMAC7.html) |
| EP (1) | EP2773773B1 (cg-RX-API-DMAC7.html) |
| JP (1) | JP6130387B2 (cg-RX-API-DMAC7.html) |
| ES (1) | ES2619713T3 (cg-RX-API-DMAC7.html) |
| WO (1) | WO2013066726A1 (cg-RX-API-DMAC7.html) |
Families Citing this family (29)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US9528160B2 (en) | 2008-11-07 | 2016-12-27 | Adaptive Biotechnolgies Corp. | Rare clonotypes and uses thereof |
| US9394567B2 (en) | 2008-11-07 | 2016-07-19 | Adaptive Biotechnologies Corporation | Detection and quantification of sample contamination in immune repertoire analysis |
| US9365901B2 (en) | 2008-11-07 | 2016-06-14 | Adaptive Biotechnologies Corp. | Monitoring immunoglobulin heavy chain evolution in B-cell acute lymphoblastic leukemia |
| GB2483810B (en) | 2008-11-07 | 2012-09-05 | Sequenta Inc | Methods for correlating clonotypes with diseases in a population |
| US9506119B2 (en) | 2008-11-07 | 2016-11-29 | Adaptive Biotechnologies Corp. | Method of sequence determination using sequence tags |
| US8748103B2 (en) | 2008-11-07 | 2014-06-10 | Sequenta, Inc. | Monitoring health and disease status using clonotype profiles |
| US8628927B2 (en) | 2008-11-07 | 2014-01-14 | Sequenta, Inc. | Monitoring health and disease status using clonotype profiles |
| EP2387627B1 (en) | 2009-01-15 | 2016-03-30 | Adaptive Biotechnologies Corporation | Adaptive immunity profiling and methods for generation of monoclonal antibodies |
| US20100330571A1 (en) | 2009-06-25 | 2010-12-30 | Robins Harlan S | Method of measuring adaptive immunity |
| US9043160B1 (en) | 2009-11-09 | 2015-05-26 | Sequenta, Inc. | Method of determining clonotypes and clonotype profiles |
| US10385475B2 (en) | 2011-09-12 | 2019-08-20 | Adaptive Biotechnologies Corp. | Random array sequencing of low-complexity libraries |
| AU2012325791B2 (en) | 2011-10-21 | 2018-04-05 | Adaptive Biotechnologies Corporation | Quantification of adaptive immune cell genomes in a complex mixture of cells |
| EP3904536B1 (en) | 2011-12-09 | 2025-10-29 | Adaptive Biotechnologies Corporation | Diagnosis of lymphoid malignancies and minimal residual disease detection |
| US9499865B2 (en) | 2011-12-13 | 2016-11-22 | Adaptive Biotechnologies Corp. | Detection and measurement of tissue-infiltrating lymphocytes |
| EP2823060B1 (en) | 2012-03-05 | 2018-02-14 | Adaptive Biotechnologies Corporation | Determining paired immune receptor chains from frequency matched subunits |
| BR112014027309A2 (pt) | 2012-05-08 | 2017-07-11 | Adaptive Biotechnologies Corp | composições e métodos para medir e calibrar a tendên-cia de amplificação em reações de pcr multiplexadas |
| CN105189779B (zh) | 2012-10-01 | 2018-05-11 | 适应生物技术公司 | 通过适应性免疫受体多样性和克隆性表征进行的免疫能力评估 |
| US9708657B2 (en) | 2013-07-01 | 2017-07-18 | Adaptive Biotechnologies Corp. | Method for generating clonotype profiles using sequence tags |
| ES2741740T3 (es) | 2014-03-05 | 2020-02-12 | Adaptive Biotechnologies Corp | Métodos que usan moléculas sintéticas que contienen segmentos de nucleótidos aleatorios |
| US10066265B2 (en) | 2014-04-01 | 2018-09-04 | Adaptive Biotechnologies Corp. | Determining antigen-specific t-cells |
| ES2777529T3 (es) | 2014-04-17 | 2020-08-05 | Adaptive Biotechnologies Corp | Cuantificación de genomas de células inmunitarias adaptativas en una mezcla compleja de células |
| US10392663B2 (en) | 2014-10-29 | 2019-08-27 | Adaptive Biotechnologies Corp. | Highly-multiplexed simultaneous detection of nucleic acids encoding paired adaptive immune receptor heterodimers from a large number of samples |
| US10246701B2 (en) | 2014-11-14 | 2019-04-02 | Adaptive Biotechnologies Corp. | Multiplexed digital quantitation of rearranged lymphoid receptors in a complex mixture |
| AU2015353581A1 (en) | 2014-11-25 | 2017-06-15 | Adaptive Biotechnologies Corporation | Characterization of adaptive immune response to vaccination or infection using immune repertoire sequencing |
| ES2858306T3 (es) | 2015-02-24 | 2021-09-30 | Adaptive Biotechnologies Corp | Método para determinar el estado de HLA mediante secuenciación del repertorio inmunitario |
| AU2016242967B2 (en) | 2015-04-01 | 2021-07-01 | Adaptive Biotechnologies Corp. | Method of identifying human compatible T cell receptors specific for an antigenic target |
| CN107345240A (zh) * | 2016-05-12 | 2017-11-14 | 眭维国 | T细胞抗原受体β链CDR3的处理方法 |
| US10428325B1 (en) | 2016-09-21 | 2019-10-01 | Adaptive Biotechnologies Corporation | Identification of antigen-specific B cell receptors |
| US11254980B1 (en) | 2017-11-29 | 2022-02-22 | Adaptive Biotechnologies Corporation | Methods of profiling targeted polynucleotides while mitigating sequencing depth requirements |
Family Cites Families (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5667967A (en) * | 1990-05-01 | 1997-09-16 | The Board Of Trustees Of The Leland Stanford Junior University | T-cell receptor varible transcripts as disease related markers |
| AU736742B2 (en) * | 1996-06-03 | 2001-08-02 | Governors Of The University Of Alberta, The | Methods for detection of rearranged DNA |
| JP5198277B2 (ja) * | 2005-11-01 | 2013-05-15 | アボツト・バイオテクノロジー・リミテツド | バイオマーカーを用いて強直性脊椎炎を診断するための方法及び組成物 |
| ES2261104B1 (es) * | 2006-06-19 | 2007-06-16 | Grifols, S.A. | "tapon para frascos de productos esteriles y utilizacion de dicho tapon en la dosificacion esteril". |
| US8748103B2 (en) * | 2008-11-07 | 2014-06-10 | Sequenta, Inc. | Monitoring health and disease status using clonotype profiles |
| AU2009333489A1 (en) * | 2008-12-30 | 2010-07-08 | Centocor Ortho Biotech Inc. | Serum markers predicting clinical response to anti-TNF antibodies in patients with ankylosing spondylitis |
| KR101323827B1 (ko) * | 2010-01-08 | 2013-10-31 | 키스트 유럽 에프게엠베하 | 강직성척추염 진단용 프라이머 및 이를 이용한 강직성 척추염 진단 방법 |
-
2012
- 2012-10-25 EP EP12844825.5A patent/EP2773773B1/en active Active
- 2012-10-25 ES ES12844825.5T patent/ES2619713T3/es active Active
- 2012-10-25 WO PCT/US2012/061977 patent/WO2013066726A1/en not_active Ceased
- 2012-10-25 US US14/350,785 patent/US20150252422A1/en not_active Abandoned
- 2012-10-25 JP JP2014539995A patent/JP6130387B2/ja active Active
-
2017
- 2017-02-03 US US15/424,550 patent/US20170191132A1/en not_active Abandoned
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