|
US5958930A
(en)
|
1991-04-08 |
1999-09-28 |
Duquesne University Of The Holy Ghost |
Pyrrolo pyrimidine and furo pyrimidine derivatives
|
|
AU3176297A
(en)
*
|
1996-06-25 |
1998-01-14 |
Novartis Ag |
Substituted 7-amino-pyrrolo{3,2-d}pyrimidines and the use thereof
|
|
US20080248046A1
(en)
|
1997-03-17 |
2008-10-09 |
Human Genome Sciences, Inc. |
Death domain containing receptor 5
|
|
TWI238824B
(en)
*
|
2001-05-14 |
2005-09-01 |
Novartis Ag |
4-amino-5-phenyl-7-cyclobutyl-pyrrolo[2,3-d]pyrimidine derivatives
|
|
US7217710B2
(en)
|
2001-10-02 |
2007-05-15 |
Smithkline Beecham Corporation |
Substituted pyrazolopyrimidines
|
|
DE10239042A1
(de)
|
2002-08-21 |
2004-03-04 |
Schering Ag |
Makrozyclische Pyrimidine, deren Herstellung und Verwendung als Arzneimittel
|
|
DE602004012559T2
(de)
|
2003-05-28 |
2009-04-30 |
Universita Degli Studi Di Siena |
4-SUBSTITUIERTE DERIVATE VON PYRAZOLOi3,4-D PYRIMIDIN UND DEREN VERWENDUNGEN
|
|
US7504396B2
(en)
|
2003-06-24 |
2009-03-17 |
Amgen Inc. |
Substituted heterocyclic compounds and methods of use
|
|
GB0320728D0
(en)
|
2003-09-04 |
2003-10-08 |
Kilminster Shaun |
Test
|
|
NZ546611A
(en)
|
2003-09-18 |
2010-02-26 |
Conforma Therapeutics Corp |
Novel heterocyclic compounds as HSP90-inhibitors
|
|
JP5520433B2
(ja)
|
2004-01-21 |
2014-06-11 |
エモリー ユニバーシティー |
病原体感染を処置するためのチロシンキナーゼインヒビターの組成物および使用
|
|
WO2005074603A2
(en)
|
2004-02-03 |
2005-08-18 |
Abbott Laboratories |
Aminobenzoxazoles as therapeutic agents
|
|
PL1713806T3
(pl)
|
2004-02-14 |
2013-09-30 |
Irm Llc |
Związki i kompozycje jako inhibitory kinaz białkowych
|
|
WO2005095382A1
(ja)
|
2004-03-30 |
2005-10-13 |
Kyowa Hakko Kogyo Co., Ltd. |
抗腫瘍剤
|
|
JP4790703B2
(ja)
*
|
2004-04-07 |
2011-10-12 |
武田薬品工業株式会社 |
環式化合物
|
|
GB0420719D0
(en)
|
2004-09-17 |
2004-10-20 |
Addex Pharmaceuticals Sa |
Novel allosteric modulators
|
|
US8575342B2
(en)
|
2004-09-30 |
2013-11-05 |
Tibotech Pharmaceuticals Ltd. |
HIV inhibiting 5-heterocyclyl pyrimidines
|
|
WO2006042102A2
(en)
*
|
2004-10-05 |
2006-04-20 |
Neurogen Corporation |
Pyrrolo-pyridine, pyrrolo-pyrimidine and related heterocyclic compounds
|
|
EP1710246A1
(en)
|
2005-04-08 |
2006-10-11 |
Schering Aktiengesellschaft |
Sulfoximine-pyrimidine Macrocycles and the salts thereof, a process for making them, and their pharmaceutical use against cancer
|
|
US20070105874A1
(en)
*
|
2005-09-23 |
2007-05-10 |
Conforma Therapeutics Corporation |
Anti-Tumor Methods Using Multi Drug Resistance Independent Synthetic HSP90 Inhibitors
|
|
US7547782B2
(en)
|
2005-09-30 |
2009-06-16 |
Bristol-Myers Squibb Company |
Met kinase inhibitors
|
|
CN101321759A
(zh)
|
2005-10-06 |
2008-12-10 |
先灵公司 |
作为蛋白激酶抑制剂的吡唑并嘧啶化合物
|
|
NZ569236A
(en)
|
2005-12-08 |
2012-06-29 |
Medarex Inc |
Human monoclonal antibodies to protein tyrosine kinase 7 (PTK7) and their use
|
|
US20080299113A1
(en)
|
2005-12-19 |
2008-12-04 |
Arnold Lee D |
Combined treatment with and composition of 6,6-bicyclic ring substituted heterobicyclic protein kinase inhibitor and anti-cancer agents
|
|
EP1803723A1
(de)
|
2006-01-03 |
2007-07-04 |
Bayer Schering Pharma Aktiengesellschaft |
(2,4,9-triaza-1(2,4)-pyrimidina-3(1,3)-benzenacyclononaphan-3^4-yl)-sulfoximid derivate als selektive inhibitoren der aurora kinase zur behandlung von krebs
|
|
AU2007233737B2
(en)
|
2006-03-30 |
2012-11-29 |
Janssen Sciences Ireland Uc |
HIV inhibiting 5-amido substituted pyrimidines
|
|
WO2007125405A2
(en)
|
2006-05-01 |
2007-11-08 |
Pfizer Products Inc. |
Substituted 2-amino-fused heterocyclic compounds
|
|
GB0610242D0
(en)
|
2006-05-23 |
2006-07-05 |
Novartis Ag |
Organic compounds
|
|
TWI398252B
(zh)
|
2006-05-26 |
2013-06-11 |
諾華公司 |
吡咯并嘧啶化合物及其用途
|
|
WO2009032703A1
(en)
|
2007-08-28 |
2009-03-12 |
Irm Llc |
2- (het) arylamino-6-aminopyridine derivatives and fused forms thereof as anaplastic lymphoma kinase inhibitors
|
|
AU2008309517B2
(en)
|
2007-10-12 |
2013-03-14 |
Astrazeneca Ab |
Inhibitors of protein kinases
|
|
CA2703519C
(en)
|
2007-11-09 |
2017-04-18 |
The Salk Institute For Biological Studies |
Use of tam receptor inhibitors as immunoenhancers and tam activators as immunosuppressors
|
|
US8338439B2
(en)
|
2008-06-27 |
2012-12-25 |
Celgene Avilomics Research, Inc. |
2,4-disubstituted pyrimidines useful as kinase inhibitors
|
|
US8399206B2
(en)
|
2008-07-10 |
2013-03-19 |
Nodality, Inc. |
Methods for diagnosis, prognosis and methods of treatment
|
|
WO2010014755A1
(en)
|
2008-07-29 |
2010-02-04 |
The Regents Of The University Of Colorado |
Methods and compounds for enhancing anti-cancer therapy
|
|
US8569466B2
(en)
|
2008-09-10 |
2013-10-29 |
Nnochiri Ekwuribe |
Aromatic carboxylic acid derivatives for treatment and prophylaxis of gastrointestinal diseases including colon cancers
|
|
TW201016676A
(en)
|
2008-10-03 |
2010-05-01 |
Astrazeneca Ab |
Heterocyclic derivatives and methods of use thereof
|
|
GB0819105D0
(en)
*
|
2008-10-17 |
2008-11-26 |
Chroma Therapeutics Ltd |
Pyrrolo-pyrimidine compounds
|
|
WO2010068863A2
(en)
|
2008-12-12 |
2010-06-17 |
Cystic Fibrosis Foundation Therapeutics, Inc. |
Pyrimidine compounds and methods of making and using same
|
|
US8765727B2
(en)
|
2009-01-23 |
2014-07-01 |
Incyte Corporation |
Macrocyclic compounds and their use as kinase inhibitors
|
|
TW201102391A
(en)
*
|
2009-03-31 |
2011-01-16 |
Biogen Idec Inc |
Certain substituted pyrimidines, pharmaceutical compositions thereof, and methods for their use
|
|
UA107791C2
(en)
|
2009-05-05 |
2015-02-25 |
Dow Agrosciences Llc |
Pesticidal compositions
|
|
WO2010129802A1
(en)
|
2009-05-06 |
2010-11-11 |
Portola Pharmaceuticals, Inc. |
Inhibitors of jak
|
|
EP2464661B1
(en)
|
2009-08-13 |
2018-01-17 |
The Johns Hopkins University |
Methods of modulating immune function with anti-b7-h7cr antibodies
|
|
CA2773661A1
(en)
*
|
2009-09-10 |
2011-03-17 |
Novartis Ag |
Ether derivatives of bicyclic heteroaryls
|
|
WO2011065800A2
(ko)
|
2009-11-30 |
2011-06-03 |
주식회사 오스코텍 |
피리미딘 유도체, 이의 제조방법 및 이를 함유하는 약학적 조성물
|
|
US9433621B2
(en)
|
2010-02-18 |
2016-09-06 |
Merck Sharp & Dohme Corp. |
Substituted pyridine and pyrimidine derivatives and their use in treating viral infections
|
|
GB201004311D0
(en)
|
2010-03-15 |
2010-04-28 |
Proximagen Ltd |
New enzyme inhibitor compounds
|
|
EP2560488B1
(en)
|
2010-04-23 |
2015-10-28 |
Cytokinetics, Inc. |
Certain amino-pyridines and amino-triazines, compositions thereof, and methods for their use
|
|
EP2571361A4
(en)
|
2010-05-19 |
2013-11-13 |
Univ North Carolina |
PYRAZOLOPYRIMIDINE COMPOUNDS FOR CANCER TREATMENT
|
|
WO2011153553A2
(en)
|
2010-06-04 |
2011-12-08 |
The Regents Of The University Of California |
Methods and compositions for kinase inhibition
|
|
JP2014005206A
(ja)
|
2010-10-22 |
2014-01-16 |
Astellas Pharma Inc |
アリールアミノヘテロ環カルボキサミド化合物
|
|
EP2640392B1
(en)
|
2010-11-18 |
2015-01-07 |
Kasina Laila Innova Pharmaceuticals Private Ltd. |
Substituted 4-(selenophen-2(or 3)-ylamino)pyrimidine compounds and methods of use thereof
|
|
US8362023B2
(en)
|
2011-01-19 |
2013-01-29 |
Hoffmann-La Roche Inc. |
Pyrazolo pyrimidines
|
|
WO2012158795A1
(en)
|
2011-05-17 |
2012-11-22 |
Principia Biopharma Inc. |
Pyrazolopyrimidine derivatives as tyrosine kinase inhibitors
|
|
PE20141371A1
(es)
|
2011-08-29 |
2014-10-13 |
Infinity Pharmaceuticals Inc |
Compuestos heterociclicos y usos de los mismos
|
|
MD20140023A2
(ro)
*
|
2011-09-22 |
2014-06-30 |
Pfizer Inc. |
Derivaţi de pirolpirimidină şi purină
|
|
BR112014007788A2
(pt)
|
2011-10-03 |
2017-04-18 |
Univ North Carolina Chapel Hill |
compostos de pirrolopirimidina para tratamento do câncer
|
|
BR112014021065A8
(pt)
|
2012-02-21 |
2018-04-24 |
Centre Nat Rech Scient |
receptores tam como cofatores de entrada do vírus
|
|
CN104662018B
(zh)
|
2012-04-20 |
2017-10-24 |
阿迪维纳斯治疗有限公司 |
取代的杂双环化合物、组合物及其医疗应用
|
|
JP2015517574A
(ja)
|
2012-05-22 |
2015-06-22 |
ザ・ユニヴァーシティ・オヴ・ノース・キャロライナ・アト・チャペル・ヒル |
がん治療のためのピリミジン化合物
|
|
WO2014062774A1
(en)
|
2012-10-17 |
2014-04-24 |
The University Of North Carolina At Chapel Hill |
Pyrazolopyrimidine compounds for the treatment of cancer
|
|
WO2014085225A1
(en)
|
2012-11-27 |
2014-06-05 |
The University Of North Carolina At Chapel Hill |
Pyrimidine compounds for the treatment of cancer
|
|
WO2015153978A1
(en)
|
2014-04-04 |
2015-10-08 |
The University Of North Carolina At Chapel Hill |
Methods for the treatment of tumors
|
|
US9649309B2
(en)
|
2014-04-11 |
2017-05-16 |
The University Of North Carolina At Chapel Hill |
Therapeutic uses of selected pyrimidine compounds with anti-Mer tyrosine kinase activity
|