JP2014526307A - 組織における細胞機能の刺激を同期させるシステムおよび方法 - Google Patents
組織における細胞機能の刺激を同期させるシステムおよび方法 Download PDFInfo
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- A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
- A61N7/00—Ultrasound therapy
- A61N2007/0004—Applications of ultrasound therapy
- A61N2007/0021—Neural system treatment
Abstract
Description
本願は、米国仮特許出願第61/531,338号(2011年9月6日出願)を基礎とする優先権および利益を主張する。該出願の内容は、その全体が参照により援用される。
本発明は、概して、生体組織における細胞機能を刺激するためのシステムおよび方法に関する。
特許、特許出願、特許公報、定期刊行物、本、論文、ウェブコンテンツ等の参照文献および他の文書の引用は、本開示を通してなされた。そのような全ての文書は、あらゆる目的のために、参照により、それらの全体が本明細書に組み込まれる。
本発明は、その主旨または本質的な特徴から逸脱することなく、他の特定の形態において具現化され得る。したがって、上記の実施形態は、全ての側面において、本明細書に記載される本発明に対する制限ではなく、例示であると見なされるべきである。
Claims (33)
- 組織を刺激するためのシステムであって、前記システムは、
第1のエネルギー源と、
第2のエネルギー源と、
前記第1および第2のエネルギー源を同期させる同期化要素と
を備え、組み合わされた効果が前記組織を刺激する、システム。 - 前記第1のエネルギー源は、電場を生成する電源である、請求項1に記載のシステム。
- 前記第2のエネルギー源は、機械場を生成する源である、請求項2に記載のシステム。
- 前記第2のエネルギー源は、超音波デバイスである、請求項3に記載のシステム。
- 前記電場は、パルス状である、請求項2に記載のシステム。
- 前記電場は、時間変動する、請求項2に記載のシステム。
- 前記電場は、複数回パルス化され、各パルスは、異なる時間の長さに対するものであることが可能である、請求項2に記載のシステム。
- 前記電場は、時間変動しない、請求項2に記載のシステム。
- 前記機械場は、パルス状である、請求項3に記載のシステム。
- 前記機械場は、時間変動する、請求項3に記載のシステム。
- 前記機械場は、複数回パルス化され、各パルスは、異なる時間の長さに対するものであることが可能である、請求項3に記載のシステム。
- 前記電場は、集束されている、請求項2に記載のシステム。
- 前記機械場は、集束されている、請求項3に記載のシステム。
- 前記電場および前記機械場の両方が集束されている、請求項3に記載のシステム。
- 前記第1および第2のエネルギー源は、背外側前頭前皮質、大脳基底核の任意の区画、側坐核、腹内側核(gastric nuclei)、脳幹、視床、下丘、上丘、中脳水道周囲灰白質、一次運動皮質、補足運動皮質、後頭葉、ブロードマン野1−48、一次感覚皮質、一次視覚皮質、一次聴覚皮質、扁桃体、海馬、蝸牛、脳神経、小脳、前頭葉、後頭葉、側頭葉、頭頂葉、皮質下構造、および脊髄から成る群から選択される脳または神経系内の構造または複数の構造に適用される、請求項1に記載のシステム。
- 前記組織は、神経組織である、請求項1に記載のシステム。
- 前記刺激の効果は、刺激の継続時間を超えて神経機能を変化させる、請求項16に記載のシステム。
- 前記同期化要素は、前記第1および第2のエネルギーを:エネルギーの規模、エネルギーの位置、エネルギーの動的挙動(すなわち、時間の関数としての挙動)、エネルギーの静的挙動、周波数領域におけるエネルギーの挙動、エネルギーの位相、エネルギー場の配向/方向(すなわち、ベクトルの挙動)、エネルギー印加の継続時間(単一もしくは複数セッションにおける)、および/またはエネルギーの組成に関連して同期させる、請求項1に記載のシステム。
- 前記同期化要素は、細胞機能に基づいてエネルギーの相対的タイミングを同期させる、請求項1に記載のシステム。
- 組織を刺激する方法であって、前記方法は、
組織の領域に第1の種類のエネルギーを提供することと、
前記組織の領域に第2の種類のエネルギーを提供することと、
前記第1および第2のエネルギー種類を同期させることと
を含み、組み合わされた効果が前記組織を刺激する、方法。 - 前記第1の種類のエネルギーは、機械場である、請求項20に記載の方法。
- 前記機械場は、超音波デバイスによって生成される、請求項21に記載の方法。
- 前記機械場は、パルス状である、請求項21に記載の方法。
- 前記機械場は、時間変動する、請求項21に記載の方法。
- 前記機械場は、複数回パルス化され、各パルスは、異なる時間の長さに対するものであることが可能である、請求項21に記載の方法。
- 前記第2の種類のエネルギーは、電場である、請求項20に記載の方法。
- 前記電場は、パルス状である、請求項26に記載の方法。
- 前記電場は、時間変動する、請求項26に記載の方法。
- 前記電場は、複数回パルス化され、各パルスは、異なる時間の長さに対するものであることが可能である、請求項26に記載の方法。
- 前記電場は、時間変動しない、請求項26に記載の方法。
- 前記第1および第2の種類のエネルギーは、背外側前頭前皮質、大脳基底核の任意の区画、側坐核、腹内側核(gastric nuclei)、脳幹、視床、下丘、上丘、中脳水道周囲灰白質、一次運動皮質、補足運動皮質、後頭葉、ブロードマン野1−48、一次感覚皮質、一次視覚皮質、一次聴覚皮質、扁桃体、海馬、蝸牛、脳神経、小脳、前頭葉、後頭葉、側頭葉、頭頂葉、皮質下構造、および脊髄から成る群から選択される脳または神経系内の構造または複数の構造に印加される、請求項20に記載の方法。
- 前記組織は、神経組織である、請求項20に記載の方法。
- 前記刺激の効果は、刺激の継続時間を超えて神経機能を変化させる、請求項32に記載の方法。
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US201161531338P | 2011-09-06 | 2011-09-06 | |
US61/531,338 | 2011-09-06 | ||
PCT/US2012/049466 WO2013036337A1 (en) | 2011-09-06 | 2012-08-03 | Systems and methods for synchronizing the stimulation of cellular function in tissue |
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JP2017250581A Division JP2018064995A (ja) | 2011-09-06 | 2017-12-27 | 組織における細胞機能の刺激を同期させるシステムおよび方法 |
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JP2014526307A true JP2014526307A (ja) | 2014-10-06 |
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US (1) | US20150360026A1 (ja) |
EP (1) | EP2776123A4 (ja) |
JP (2) | JP2014526307A (ja) |
WO (1) | WO2013036337A1 (ja) |
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WO2016069178A1 (en) * | 2014-10-28 | 2016-05-06 | Highland Instruments, Inc. | Adjustable headpiece with anatomical markers and methods of use thereof |
US10434328B2 (en) * | 2014-11-17 | 2019-10-08 | Richard D. Gilson | Non-invasive in vivo deep nerve cell stimulation system and method |
JP2019528914A (ja) * | 2016-09-15 | 2019-10-17 | センス、テクノロジー、インコーポレイテッドSense Technology Inc. | 非外傷性筋骨格疼痛の同相処置のための方法および装置 |
EP3684463A4 (en) | 2017-09-19 | 2021-06-23 | Neuroenhancement Lab, LLC | NEURO-ACTIVATION PROCESS AND APPARATUS |
US11717686B2 (en) | 2017-12-04 | 2023-08-08 | Neuroenhancement Lab, LLC | Method and apparatus for neuroenhancement to facilitate learning and performance |
US11318277B2 (en) | 2017-12-31 | 2022-05-03 | Neuroenhancement Lab, LLC | Method and apparatus for neuroenhancement to enhance emotional response |
US11364361B2 (en) | 2018-04-20 | 2022-06-21 | Neuroenhancement Lab, LLC | System and method for inducing sleep by transplanting mental states |
WO2020056418A1 (en) | 2018-09-14 | 2020-03-19 | Neuroenhancement Lab, LLC | System and method of improving sleep |
US11318330B2 (en) | 2018-09-26 | 2022-05-03 | General Electric Company | Neuromodulation techniques |
KR102525621B1 (ko) * | 2019-09-19 | 2023-04-26 | 기초과학연구원 | 세타-버스트 초음파를 이용한 신경 가소성 조절 장치 및 조절방법 |
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- 2012-08-03 JP JP2014529718A patent/JP2014526307A/ja active Pending
- 2012-08-03 WO PCT/US2012/049466 patent/WO2013036337A1/en active Application Filing
- 2012-08-03 EP EP12830803.8A patent/EP2776123A4/en not_active Withdrawn
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WO2013036337A1 (en) | 2013-03-14 |
EP2776123A1 (en) | 2014-09-17 |
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