JP2014524479A - エストロゲン受容体リガンドおよびその使用方法 - Google Patents

エストロゲン受容体リガンドおよびその使用方法 Download PDF

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Publication number
JP2014524479A
JP2014524479A JP2014527312A JP2014527312A JP2014524479A JP 2014524479 A JP2014524479 A JP 2014524479A JP 2014527312 A JP2014527312 A JP 2014527312A JP 2014527312 A JP2014527312 A JP 2014527312A JP 2014524479 A JP2014524479 A JP 2014524479A
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JP
Japan
Prior art keywords
compound
another embodiment
prostate cancer
formula
crpc
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
JP2014527312A
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English (en)
Japanese (ja)
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JP2014524479A5 (https=
Inventor
ジェイムズ ダルトン，
ミッチェル エス． シュタイナー，
クリストファー シー． コス，
Original Assignee
ジーティーエックス・インコーポレイテッド
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from US13/215,679 external-priority patent/US9427418B2/en
Application filed by ジーティーエックス・インコーポレイテッド filed Critical ジーティーエックス・インコーポレイテッド
Priority claimed from PCT/US2012/052141 external-priority patent/WO2013043304A1/en
Publication of JP2014524479A publication Critical patent/JP2014524479A/ja
Publication of JP2014524479A5 publication Critical patent/JP2014524479A5/ja
Pending legal-status Critical Current

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Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/13—Amines
    • A61K31/135—Amines having aromatic rings, e.g. ketamine, nortriptyline
    • A61K31/137—Arylalkylamines, e.g. amphetamine, epinephrine, salbutamol, ephedrine or methadone
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/16—Amides, e.g. hydroxamic acids
    • A61K31/165—Amides, e.g. hydroxamic acids having aromatic rings, e.g. colchicine, atenolol, progabide
    • A61K31/167—Amides, e.g. hydroxamic acids having aromatic rings, e.g. colchicine, atenolol, progabide having the nitrogen of a carboxamide group directly attached to the aromatic ring, e.g. lidocaine, paracetamol
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
    • A61K31/445—Non condensed piperidines, e.g. piperocaine
    • A61K31/4453—Non condensed piperidines, e.g. piperocaine only substituted in position 1, e.g. propipocaine, diperodon
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
    • A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca

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  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Emergency Medicine (AREA)
  • Pain & Pain Management (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Steroid Compounds (AREA)
JP2014527312A 2011-08-23 2012-08-23 エストロゲン受容体リガンドおよびその使用方法 Pending JP2014524479A (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US13/215,679 2011-08-23
US13/215,679 US9427418B2 (en) 2009-02-23 2011-08-23 Estrogen receptor ligands and methods of use thereof
PCT/US2012/052141 WO2013043304A1 (en) 2009-02-23 2012-08-23 Estrogen receptor ligands and methods of use thereof

Publications (2)

Publication Number Publication Date
JP2014524479A true JP2014524479A (ja) 2014-09-22
JP2014524479A5 JP2014524479A5 (https=) 2015-10-08

Family

ID=48444651

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2014527312A Pending JP2014524479A (ja) 2011-08-23 2012-08-23 エストロゲン受容体リガンドおよびその使用方法

Country Status (10)

Country Link
EP (1) EP2747562A4 (https=)
JP (1) JP2014524479A (https=)
KR (1) KR20140064906A (https=)
CN (1) CN103957706A (https=)
AU (1) AU2012312902B2 (https=)
CA (1) CA2845890A1 (https=)
IL (1) IL231070A0 (https=)
IN (1) IN2014DN01959A (https=)
MX (1) MX2014002105A (https=)
RU (1) RU2014111060A (https=)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2020535171A (ja) * 2017-09-27 2020-12-03 ターグイミューン セラピューティクス アーゲー 去勢抵抗性前立腺癌
TWI840496B (zh) * 2019-01-30 2024-05-01 美商艾瑞岡醫藥公司 用於治療轉移性去勢敏感性前列腺癌之抗雄性激素
MX2021009119A (es) * 2019-02-01 2022-01-18 Fond Per Listituto Oncologico Di Ricerca Ior Metodos de tratamiento contra el cancer de prostata resistente a la castracion.

Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2010524939A (ja) * 2007-04-16 2010-07-22 ジーティーエックス・インコーポレイテッド 核内受容体結合剤
WO2010096801A1 (en) * 2009-02-23 2010-08-26 Gtx, Inc. Estrogen receptor ligands and methods of use thereof

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EA201500845A1 (ru) * 2005-11-28 2016-04-29 Джи Ти Икс, ИНК. Агенты, связывающиеся с ядерными рецепторами
US8546451B2 (en) * 2005-11-28 2013-10-01 Gtx, Inc. Estrogen receptor ligands and methods of use thereof

Patent Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2010524939A (ja) * 2007-04-16 2010-07-22 ジーティーエックス・インコーポレイテッド 核内受容体結合剤
WO2010096801A1 (en) * 2009-02-23 2010-08-26 Gtx, Inc. Estrogen receptor ligands and methods of use thereof

Non-Patent Citations (1)

* Cited by examiner, † Cited by third party
Title
BJU INTERNATIONAL, vol. 101, no. 3, JPN6016024782, 2008, pages 271 - 274, ISSN: 0003347558 *

Also Published As

Publication number Publication date
IL231070A0 (en) 2014-03-31
AU2012312902B2 (en) 2016-03-17
KR20140064906A (ko) 2014-05-28
MX2014002105A (es) 2014-09-25
AU2012312902A1 (en) 2013-05-23
RU2014111060A (ru) 2015-09-27
CN103957706A (zh) 2014-07-30
EP2747562A1 (en) 2014-07-02
EP2747562A4 (en) 2015-05-06
CA2845890A1 (en) 2013-03-28
IN2014DN01959A (https=) 2015-05-15

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