JP2014524479A - エストロゲン受容体リガンドおよびその使用方法 - Google Patents

エストロゲン受容体リガンドおよびその使用方法 Download PDF

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Publication number
JP2014524479A
JP2014524479A JP2014527312A JP2014527312A JP2014524479A JP 2014524479 A JP2014524479 A JP 2014524479A JP 2014527312 A JP2014527312 A JP 2014527312A JP 2014527312 A JP2014527312 A JP 2014527312A JP 2014524479 A JP2014524479 A JP 2014524479A
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JP
Japan
Prior art keywords
compound
another embodiment
prostate cancer
formula
crpc
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
JP2014527312A
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English (en)
Japanese (ja)
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JP2014524479A5 (enExample
Inventor
ジェイムズ ダルトン，
ミッチェル エス． シュタイナー，
クリストファー シー． コス，
Original Assignee
ジーティーエックス・インコーポレイテッド
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from US13/215,679 external-priority patent/US9427418B2/en
Application filed by ジーティーエックス・インコーポレイテッド filed Critical ジーティーエックス・インコーポレイテッド
Priority claimed from PCT/US2012/052141 external-priority patent/WO2013043304A1/en
Publication of JP2014524479A publication Critical patent/JP2014524479A/ja
Publication of JP2014524479A5 publication Critical patent/JP2014524479A5/ja
Pending legal-status Critical Current

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Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/13—Amines
    • A61K31/135—Amines having aromatic rings, e.g. ketamine, nortriptyline
    • A61K31/137—Arylalkylamines, e.g. amphetamine, epinephrine, salbutamol, ephedrine or methadone
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/16—Amides, e.g. hydroxamic acids
    • A61K31/165—Amides, e.g. hydroxamic acids having aromatic rings, e.g. colchicine, atenolol, progabide
    • A61K31/167—Amides, e.g. hydroxamic acids having aromatic rings, e.g. colchicine, atenolol, progabide having the nitrogen of a carboxamide group directly attached to the aromatic ring, e.g. lidocaine, paracetamol
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
    • A61K31/445—Non condensed piperidines, e.g. piperocaine
    • A61K31/4453—Non condensed piperidines, e.g. piperocaine only substituted in position 1, e.g. propipocaine, diperodon
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
    • A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca

Landscapes

  • Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Emergency Medicine (AREA)
  • Pain & Pain Management (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Steroid Compounds (AREA)
JP2014527312A 2011-08-23 2012-08-23 エストロゲン受容体リガンドおよびその使用方法 Pending JP2014524479A (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US13/215,679 US9427418B2 (en) 2009-02-23 2011-08-23 Estrogen receptor ligands and methods of use thereof
US13/215,679 2011-08-23
PCT/US2012/052141 WO2013043304A1 (en) 2009-02-23 2012-08-23 Estrogen receptor ligands and methods of use thereof

Publications (2)

Publication Number Publication Date
JP2014524479A true JP2014524479A (ja) 2014-09-22
JP2014524479A5 JP2014524479A5 (enExample) 2015-10-08

Family

ID=48444651

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2014527312A Pending JP2014524479A (ja) 2011-08-23 2012-08-23 エストロゲン受容体リガンドおよびその使用方法

Country Status (10)

Country Link
EP (1) EP2747562A4 (enExample)
JP (1) JP2014524479A (enExample)
KR (1) KR20140064906A (enExample)
CN (1) CN103957706A (enExample)
AU (1) AU2012312902B2 (enExample)
CA (1) CA2845890A1 (enExample)
IL (1) IL231070A0 (enExample)
IN (1) IN2014DN01959A (enExample)
MX (1) MX2014002105A (enExample)
RU (1) RU2014111060A (enExample)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN111164093A (zh) * 2017-09-27 2020-05-15 塔尔格免疫治疗有限公司 去势抵抗性前列腺癌
JP2022523094A (ja) * 2019-01-30 2022-04-21 アラゴン ファーマシューティカルズ，インコーポレイテッド 転移性去勢感受性前立腺癌の治療のための抗アンドロゲン剤
CN113853216A (zh) * 2019-02-01 2021-12-28 肿瘤学研究所基金会(Ior) 治疗去势抵抗性前列腺癌的方法

Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2010524939A (ja) * 2007-04-16 2010-07-22 ジーティーエックス・インコーポレイテッド 核内受容体結合剤
WO2010096801A1 (en) * 2009-02-23 2010-08-26 Gtx, Inc. Estrogen receptor ligands and methods of use thereof

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US8546451B2 (en) * 2005-11-28 2013-10-01 Gtx, Inc. Estrogen receptor ligands and methods of use thereof
EA023472B1 (ru) * 2005-11-28 2016-06-30 Джи Ти Икс, ИНК. Агенты, связывающиеся с ядерными рецепторами

Patent Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2010524939A (ja) * 2007-04-16 2010-07-22 ジーティーエックス・インコーポレイテッド 核内受容体結合剤
WO2010096801A1 (en) * 2009-02-23 2010-08-26 Gtx, Inc. Estrogen receptor ligands and methods of use thereof

Non-Patent Citations (1)

* Cited by examiner, † Cited by third party
Title
BJU INTERNATIONAL, vol. 101, no. 3, JPN6016024782, 2008, pages 271 - 274, ISSN: 0003347558 *

Also Published As

Publication number Publication date
AU2012312902B2 (en) 2016-03-17
MX2014002105A (es) 2014-09-25
KR20140064906A (ko) 2014-05-28
CN103957706A (zh) 2014-07-30
CA2845890A1 (en) 2013-03-28
RU2014111060A (ru) 2015-09-27
IN2014DN01959A (enExample) 2015-05-15
EP2747562A4 (en) 2015-05-06
IL231070A0 (en) 2014-03-31
EP2747562A1 (en) 2014-07-02
AU2012312902A1 (en) 2013-05-23

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