JP2014521606A5 - - Google Patents
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- Publication number
- JP2014521606A5 JP2014521606A5 JP2014521778A JP2014521778A JP2014521606A5 JP 2014521606 A5 JP2014521606 A5 JP 2014521606A5 JP 2014521778 A JP2014521778 A JP 2014521778A JP 2014521778 A JP2014521778 A JP 2014521778A JP 2014521606 A5 JP2014521606 A5 JP 2014521606A5
- Authority
- JP
- Japan
- Prior art keywords
- composition
- ocular surface
- bromfenac
- treating
- weight
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
- 206010020751 Hypersensitivity Diseases 0.000 claims description 29
- 230000007815 allergy Effects 0.000 claims description 29
- ZBPLOVFIXSTCRZ-UHFFFAOYSA-N bromfenac Chemical compound NC1=C(CC(O)=O)C=CC=C1C(=O)C1=CC=C(Br)C=C1 ZBPLOVFIXSTCRZ-UHFFFAOYSA-N 0.000 claims description 28
- 229960003655 bromfenac Drugs 0.000 claims description 28
- 208000026935 allergic disease Diseases 0.000 claims description 27
- 229920002807 Thiomer Polymers 0.000 claims description 17
- 230000009969 flowable effect Effects 0.000 claims description 14
- 238000013268 sustained release Methods 0.000 claims description 14
- 239000012730 sustained-release form Substances 0.000 claims description 14
- 125000003178 carboxy group Chemical group [H]OC(*)=O 0.000 claims description 12
- 229920000642 polymer Polymers 0.000 claims description 12
- 229940124549 vasodilator Drugs 0.000 claims description 8
- 239000003071 vasodilator agent Substances 0.000 claims description 8
- 229920000148 Polycarbophil calcium Polymers 0.000 claims description 6
- 229950005134 polycarbophil Drugs 0.000 claims description 6
- 244000036975 Ambrosia artemisiifolia Species 0.000 claims description 3
- 235000003129 Ambrosia artemisiifolia var elatior Nutrition 0.000 claims description 3
- 239000013566 allergen Substances 0.000 claims description 3
- 235000003484 annual ragweed Nutrition 0.000 claims description 3
- 235000006263 bur ragweed Nutrition 0.000 claims description 3
- 235000003488 common ragweed Nutrition 0.000 claims description 3
- 235000009736 ragweed Nutrition 0.000 claims description 3
- 230000001932 seasonal effect Effects 0.000 claims description 3
- BALXUFOVQVENIU-GNAZCLTHSA-N Ephedrine hydrochloride Chemical group Cl.CN[C@@H](C)[C@H](O)C1=CC=CC=C1 BALXUFOVQVENIU-GNAZCLTHSA-N 0.000 claims description 2
- 241000124008 Mammalia Species 0.000 claims description 2
- DJDFFEBSKJCGHC-UHFFFAOYSA-N Naphazoline Chemical compound Cl.C=1C=CC2=CC=CC=C2C=1CC1=NCCN1 DJDFFEBSKJCGHC-UHFFFAOYSA-N 0.000 claims description 2
- 241000209504 Poaceae Species 0.000 claims description 2
- 229960002534 ephedrine hydrochloride Drugs 0.000 claims description 2
- 239000012530 fluid Substances 0.000 claims description 2
- 229960004760 naphazoline hydrochloride Drugs 0.000 claims description 2
- 229960003733 phenylephrine hydrochloride Drugs 0.000 claims description 2
- OCYSGIYOVXAGKQ-FVGYRXGTSA-N phenylephrine hydrochloride Chemical compound [H+].[Cl-].CNC[C@H](O)C1=CC=CC(O)=C1 OCYSGIYOVXAGKQ-FVGYRXGTSA-N 0.000 claims description 2
- 229940021790 tetrahydrozoline hydrochloride Drugs 0.000 claims description 2
- BJORNXNYWNIWEY-UHFFFAOYSA-N tetrahydrozoline hydrochloride Chemical compound Cl.N1CCN=C1C1C2=CC=CC=C2CCC1 BJORNXNYWNIWEY-UHFFFAOYSA-N 0.000 claims description 2
- 238000000034 method Methods 0.000 description 14
- 244000025254 Cannabis sativa Species 0.000 description 1
- 206010048908 Seasonal allergy Diseases 0.000 description 1
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US13/188,730 | 2011-07-22 | ||
| US13/188,730 US20130023575A1 (en) | 2011-07-22 | 2011-07-22 | Compositions and methods for the treatment of ocular surface allergies |
| PCT/US2012/047359 WO2013016125A1 (en) | 2011-07-22 | 2012-07-19 | Compositions and methods for the treatment of ocular surface allergies |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2014521606A JP2014521606A (ja) | 2014-08-28 |
| JP2014521606A5 true JP2014521606A5 (https=) | 2015-08-13 |
Family
ID=47556198
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2014521778A Pending JP2014521606A (ja) | 2011-07-22 | 2012-07-19 | 眼表面アレルギーの処置のための組成物および方法 |
Country Status (5)
| Country | Link |
|---|---|
| US (1) | US20130023575A1 (https=) |
| EP (1) | EP2734188A4 (https=) |
| JP (1) | JP2014521606A (https=) |
| CA (1) | CA2840727A1 (https=) |
| WO (1) | WO2013016125A1 (https=) |
Families Citing this family (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CA2911983A1 (en) * | 2013-06-19 | 2014-12-24 | Sentiss Research Center | Stable bromfenac solution |
| WO2015087267A2 (en) * | 2013-12-12 | 2015-06-18 | Sentiss Pharma Private Limited | Stable bromfenac ophthalmic solution |
| US11213480B1 (en) | 2015-08-06 | 2022-01-04 | Hikma Pharmaceuticals International Limited | Phenylephrine hydrochloride ready-to-use solution |
| CN111743858B (zh) * | 2019-03-29 | 2023-06-27 | 天津药业研究院股份有限公司 | 一种溴芬酸钠的药物组合物 |
Family Cites Families (11)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5192535A (en) * | 1988-02-08 | 1993-03-09 | Insite Vision Incorporated | Ophthalmic suspensions |
| US5558876A (en) * | 1995-03-29 | 1996-09-24 | Alcon Laboratories, Inc. | Topical ophthalmic acidic drug formulations |
| JP2002308764A (ja) * | 2001-02-09 | 2002-10-23 | Taisho Pharmaceut Co Ltd | 眼科用医薬組成物 |
| PT1586316E (pt) * | 2003-01-21 | 2008-05-28 | Senju Pharma Co | Preparação líquida aquosa contendo ácido 2-amino-3-(4- bromobenzoil)fenilacético |
| US20050202097A1 (en) * | 2004-03-12 | 2005-09-15 | Melbj Holdings, Llc, Florida | Lubricant for the ocular surface |
| JP2007528897A (ja) * | 2004-03-12 | 2007-10-18 | メルビ ホールディングス， エルエルシー | 眼表面用の潤滑剤 |
| US8372814B2 (en) * | 2004-06-07 | 2013-02-12 | Ista Pharmaceuticals, Inc. | Ophthalmic formulations and uses thereof |
| AU2007208054A1 (en) * | 2006-01-25 | 2007-08-02 | Aciex Therapeutics, Inc. | Formulations and methods for treating dry eye |
| EP2089036A1 (en) * | 2006-11-02 | 2009-08-19 | Riolan Technologies, Inc. | Methods of treating an ocular allergy with low dose dexamethasone |
| US8778999B2 (en) * | 2009-03-05 | 2014-07-15 | Insite Vision Incorporated | Non-steroidal anti-inflammatory ophthalmic compositions |
| WO2010141834A1 (en) * | 2009-06-05 | 2010-12-09 | Aciex Therapeutics, Inc. | Ophthalmic formulations of fluticasone and methods of use |
-
2011
- 2011-07-22 US US13/188,730 patent/US20130023575A1/en not_active Abandoned
-
2012
- 2012-07-19 WO PCT/US2012/047359 patent/WO2013016125A1/en not_active Ceased
- 2012-07-19 JP JP2014521778A patent/JP2014521606A/ja active Pending
- 2012-07-19 EP EP12817001.6A patent/EP2734188A4/en not_active Ceased
- 2012-07-19 CA CA2840727A patent/CA2840727A1/en not_active Abandoned
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