JP2014517050A5 - - Google Patents

Download PDF

Info

Publication number
JP2014517050A5
JP2014517050A5 JP2014516318A JP2014516318A JP2014517050A5 JP 2014517050 A5 JP2014517050 A5 JP 2014517050A5 JP 2014516318 A JP2014516318 A JP 2014516318A JP 2014516318 A JP2014516318 A JP 2014516318A JP 2014517050 A5 JP2014517050 A5 JP 2014517050A5
Authority
JP
Japan
Prior art keywords
week
compound
dose
disorder
schizophrenia
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
JP2014516318A
Other languages
English (en)
Japanese (ja)
Other versions
JP6140151B2 (ja
JP2014517050A (ja
Filing date
Publication date
Application filed filed Critical
Priority claimed from PCT/EP2012/061779 external-priority patent/WO2012175531A1/en
Publication of JP2014517050A publication Critical patent/JP2014517050A/ja
Publication of JP2014517050A5 publication Critical patent/JP2014517050A5/ja
Application granted granted Critical
Publication of JP6140151B2 publication Critical patent/JP6140151B2/ja
Active legal-status Critical Current
Anticipated expiration legal-status Critical

Links

JP2014516318A 2011-06-20 2012-06-20 統合失調症の処置において4−((1r,3s)−6−クロロ−3−フェニル−インダン−1−イル)−1,2,2−トリメチル−ピペラジンおよびその塩を投与する方法 Active JP6140151B2 (ja)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
US201161498653P 2011-06-20 2011-06-20
DKPA201100465 2011-06-20
US61/498,653 2011-06-20
DKPA201100465 2011-06-20
PCT/EP2012/061779 WO2012175531A1 (en) 2011-06-20 2012-06-20 Method of administration of 4-((1r,3s)-6-chloro-3-phenyl-indan-1-yl)-1,2,2-trimethyl-piperazine and the salts thereof in the treatment of schizophrenia

Publications (3)

Publication Number Publication Date
JP2014517050A JP2014517050A (ja) 2014-07-17
JP2014517050A5 true JP2014517050A5 (US20070167479A1-20070719-C00034.png) 2016-11-17
JP6140151B2 JP6140151B2 (ja) 2017-05-31

Family

ID=58794324

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2014516318A Active JP6140151B2 (ja) 2011-06-20 2012-06-20 統合失調症の処置において4−((1r,3s)−6−クロロ−3−フェニル−インダン−1−イル)−1,2,2−トリメチル−ピペラジンおよびその塩を投与する方法

Country Status (22)

Country Link
US (1) US9610287B2 (US20070167479A1-20070719-C00034.png)
EP (1) EP2720698B1 (US20070167479A1-20070719-C00034.png)
JP (1) JP6140151B2 (US20070167479A1-20070719-C00034.png)
KR (1) KR101900989B1 (US20070167479A1-20070719-C00034.png)
CN (1) CN103608015A (US20070167479A1-20070719-C00034.png)
AU (1) AU2012274150B2 (US20070167479A1-20070719-C00034.png)
BR (1) BR112013032178A2 (US20070167479A1-20070719-C00034.png)
CA (1) CA2838055C (US20070167479A1-20070719-C00034.png)
DK (1) DK2720698T3 (US20070167479A1-20070719-C00034.png)
ES (1) ES2694298T3 (US20070167479A1-20070719-C00034.png)
HR (1) HRP20181684T1 (US20070167479A1-20070719-C00034.png)
IL (1) IL230060A (US20070167479A1-20070719-C00034.png)
JO (1) JO3421B1 (US20070167479A1-20070719-C00034.png)
LT (1) LT2720698T (US20070167479A1-20070719-C00034.png)
MX (1) MX349754B (US20070167479A1-20070719-C00034.png)
PL (1) PL2720698T3 (US20070167479A1-20070719-C00034.png)
RS (1) RS57944B1 (US20070167479A1-20070719-C00034.png)
RU (1) RU2613177C2 (US20070167479A1-20070719-C00034.png)
SI (1) SI2720698T1 (US20070167479A1-20070719-C00034.png)
TW (1) TWI552751B (US20070167479A1-20070719-C00034.png)
WO (1) WO2012175531A1 (US20070167479A1-20070719-C00034.png)
ZA (1) ZA201309617B (US20070167479A1-20070719-C00034.png)

Families Citing this family (79)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US7402400B2 (en) 2001-07-03 2008-07-22 Regents Of The University Of California Mammalian sweet taste receptors
WO2001036444A1 (en) 1999-11-17 2001-05-25 Mendel Biotechnology, Inc. Plant developmental genes
US6458538B1 (en) 1999-12-14 2002-10-01 Ptc Therapeutics, Inc. Methods of assaying for compounds that inhibit premature translation termination and nonsense-mediated RNA decay
TW201006846A (en) 2000-03-07 2010-02-16 Senomyx Inc T1R taste receptor and genes encidung same
EP2410060A1 (en) 2000-08-22 2012-01-25 Mendel Biotechnology, Inc. Genes for modifying plant traits IV
US7045283B2 (en) 2000-10-18 2006-05-16 The Regents Of The University Of California Methods of high-throughput screening for internalizing antibodies
US7883856B2 (en) 2001-04-05 2011-02-08 Senomyx Inc. Identification of bitter ligands that specifically activate human T2R receptors and related assays for identifying human bitter taste modulators
AU2002326315B2 (en) 2001-06-26 2007-07-05 Senomyx, Inc. T1R hetero-oligomeric taste receptors and cell lines that express said receptors and use thereof for identification of taste compounds
US7871619B2 (en) 2001-11-30 2011-01-18 Chemocentryx, Inc. Compositions and methods for detecting and treating diseases and conditions related to chemokine receptors
WO2005016232A2 (en) 2002-08-01 2005-02-24 The Regents Of The University Of California Therapeutic monoclonal antibodies that neutralize botulinum neurotoxins
WO2004016733A2 (en) 2002-08-16 2004-02-26 Agensys, Inc. Nucleic acid and corresponding protein entitled 251p5g2 useful in treatment and detection of cancer
PT1546336E (pt) 2002-09-18 2012-04-09 Mendel Biotechnology Inc Polinucleótidos e polipéptidos em plantas
CN101090729B (zh) 2003-05-30 2014-07-23 艾更斯司股份有限公司 前列腺干细胞抗原(psca)变体及其序列
US7794948B2 (en) 2003-11-07 2010-09-14 Vermilllion, Inc. Biomarkers for alzheimer's disease
EP2322637B1 (en) 2003-12-24 2016-05-18 Novo Nordisk A/S Transgenic mouse comprising a polynucleotide encoding human or humanized C5AR
CN1964740A (zh) 2004-04-02 2007-05-16 加利福尼亚大学董事会 治疗和预防与αVβ5整联蛋白有关的疾病的方法和组合物
US7939251B2 (en) 2004-05-06 2011-05-10 Roche Molecular Systems, Inc. SENP1 as a marker for cancer
AU2005250370B2 (en) 2004-05-28 2010-04-01 Agensys, Inc. Antibodies and related molecules that bind to PSCA proteins
CA2571243A1 (en) 2004-06-21 2006-01-05 The Board Of Trustees Of The Leland Stanford Junior University Genes and pathways differentially expressed in bipolar disorder and/or major depressive disorder
US7850960B2 (en) 2004-12-30 2010-12-14 University Of Washington Methods for regulation of stem cells
US7700738B2 (en) 2005-01-27 2010-04-20 The Regents Of The University Of California Therapeutic monoclonal antibodies that neutralize botulinum neurotoxins
WO2006105488A2 (en) 2005-03-31 2006-10-05 Agensys, Inc. Antibodies and related molecules that bind to 161p2f10b proteins
PL3117833T3 (pl) 2005-07-19 2019-06-28 Stemgen S.P.A. Hamowanie przez lif zdolności do tworzenia guzów przez komórki macierzyste guza
ES2658859T3 (es) 2005-10-20 2018-03-12 Senomyx, Inc. Receptores del sabor dulce-umami y umami-dulce humanos quiméricos
EP1945261A4 (en) 2005-11-07 2010-05-12 Scripps Research Inst COMPOSITIONS AND METHODS FOR CONTROLLING THE SPECIFICITY OF TISSUE FACTOR SIGNALING
EP2564864B8 (en) 2005-11-12 2015-05-13 The Board of Trustees of The Leland Stanford Junior University FGF2-related methods for diagnosing and treating depression
CN101437933B (zh) 2005-12-28 2013-11-06 斯克里普斯研究所 作为药物靶标的天然反义和非编码的rna转录物
CA2646597A1 (en) 2006-03-21 2007-09-27 The Regents Of The University Of California N-cadherin and ly6 e: targets for cancer diagnosis and therapy
US20100278821A1 (en) 2006-03-21 2010-11-04 The Regents Of The University Of California N-cadherin: target for cancer diagnosis and therapy
US7572618B2 (en) 2006-06-30 2009-08-11 Bristol-Myers Squibb Company Polynucleotides encoding novel PCSK9 variants
EP2423333A1 (en) 2006-08-25 2012-02-29 Oncotherapy Science, Inc. Prognostic markers and therapeutic targets for lung cancer
ES2484142T3 (es) 2006-09-06 2014-08-11 The Regents Of The University Of California Diagnóstico molecular y clasificación del melanoma maligno
WO2008127314A1 (en) 2006-11-22 2008-10-23 President And Fellows Of Harvard College High-sensitivity nanoscale wire sensors
EP2581081A3 (en) 2007-06-01 2013-07-31 The Trustees Of Princeton University Treatment of viral infections by modulation of host cell metabolic pathways
JP5555626B2 (ja) 2007-08-13 2014-07-23 バクスター・インターナショナル・インコーポレイテッド 多発性硬化症、アルツハイマー病およびパーキンソン病を処置するためのケモカインのivig調節
KR101599715B1 (ko) 2007-08-21 2016-03-08 세노믹스, 인코포레이티드 인간 t2r 쓴맛 수용체 및 이의 용도
CA2697992C (en) 2007-10-04 2017-08-22 Zymogenetics, Inc. B7 family member zb7h6 and related compositions and methods
CA2703165A1 (en) 2007-10-22 2009-04-30 The Regents Of The University Of California Biomarkers for prenatal diagnosis of congenital cytomegalovirus
CA2960659C (en) 2007-11-09 2021-07-13 The Salk Institute For Biological Studies Use of tam receptor inhibitors as immunoenhancers and tam activators as immunosuppressors
CA2718904C (en) 2008-03-17 2017-01-03 The Scripps Research Institute Combined chemical and genetic approaches for generation of induced pluripotent stem cells
CN102083850B (zh) 2008-04-21 2015-08-12 加利福尼亚大学董事会 选择性高亲和力多齿配体及其制备方法
WO2010017248A2 (en) 2008-08-04 2010-02-11 University Of Miami Sting (stimulator of interferon genes), a regulator of innate immune responses
AU2009298879A1 (en) 2008-09-23 2010-04-08 President And Fellows Of Harvard College SIRT4 and uses thereof
JP5798037B2 (ja) 2008-11-06 2015-10-21 ユニバーシティ オブ マイアミ 蛋白尿腎疾患の病因における可溶性uPARの役割
EP2687609B1 (en) 2008-11-10 2017-01-04 The United States of America, as represented by The Secretary, Department of Health and Human Services Method for treating solid tumor
CA2745266C (en) 2008-12-03 2018-04-10 Yue Xu Stem cell cultures
CN104130976A (zh) 2008-12-17 2014-11-05 斯克里普斯研究所 干细胞的产生和保持
US20100291100A1 (en) 2009-03-27 2010-11-18 Gojo Industries, Inc. Compositions And Methods For Screening And Using Compounds Antagonizing Spore-Surface Interactions
BR112012001463A2 (pt) 2009-07-24 2016-03-15 Univ California métodos e composições para tratar e prevenir doença associada à integrina alfavbeta5
WO2011019929A1 (en) 2009-08-14 2011-02-17 The Regents Of The University Of California Methods of diagnosing and treating autism
US20120148604A1 (en) 2009-08-20 2012-06-14 Transposagen Biopharmaceuticals, Inc. Trp inhibitors and uses thereof
WO2011038228A1 (en) 2009-09-24 2011-03-31 President And Fellows Of Harvard College Bent nanowires and related probing of species
ES2365343B1 (es) 2009-11-19 2012-07-10 Fundación Centro Nacional De Investigaciones Cardiovasculares Carlos Iii Uso de cd98 como marcador de receptividad endometrial.
US20130137584A1 (en) 2010-02-01 2013-05-30 The Regents Of The University Of California Novel diagnostic and therapeutic targets associated with or regulated by n-cadherin expression and/or epithelial to mesenchymal transition (emt) in prostate cancer and other malignancies
WO2012052391A1 (en) 2010-10-19 2012-04-26 Glaxo Group Limited Polypeptide with jmjd3 catalytic activity
WO2012109495A1 (en) 2011-02-09 2012-08-16 Metabolic Solutions Development Company, Llc Cellular targets of thiazolidinediones
WO2012119989A2 (en) 2011-03-04 2012-09-13 Oryzon Genomics, S.A. Methods and antibodies for the diagnosis and treatment of cancer
US20120301904A1 (en) 2011-04-26 2012-11-29 Prosetta Antiviral, Inc Multiprotein assemblies
US9408832B2 (en) 2012-03-14 2016-08-09 University Of Central Florida Research Foundation, Inc. LIM kinasemodulating agents for neurofibromatoses therapy and methods for screening for same
US20150087628A1 (en) 2012-04-10 2015-03-26 The Regents Of The University Of California Compositions and methods for treating cancer
EP2841450A2 (en) 2012-04-24 2015-03-04 University of Miami Perforin 2 defense against invasive and multidrug resistant pathogens
EP2877211A4 (en) 2012-07-25 2016-02-10 Salk Inst For Biological Studi REGULATION OF THE INTERACTION BETWEEN TAM LIGANDS AND LIPID MEMBRANES CONTAINING PHOSPHATIDYLSERIN
US9750705B2 (en) 2012-08-31 2017-09-05 The Regents Of The University Of California Agents useful for treating obesity, diabetes and related disorders
AU2013204200B2 (en) 2012-10-11 2016-10-20 Brandeis University Treatment of amyotrophic lateral sclerosis
US20140120116A1 (en) 2012-10-26 2014-05-01 The Chinese University Of Hong Kong Treatment of cancer using smad3 inhibitor
CN105074462B (zh) 2013-02-07 2019-08-23 加利福尼亚大学董事会 翻译谱分析在鉴定用于治疗性处理的靶标分子中的应用
WO2014144844A1 (en) 2013-03-15 2014-09-18 The Board Of Trustees Of The Leland Stanford Junior University tRNA DERIVED SMALL RNAs (tsRNAs) INVOLVED IN CELL VIABILITY
US10280169B2 (en) 2013-12-11 2019-05-07 Biogen Ma Inc. Biaryl bruton's tyrosine kinase inhibitors
EP3079475B1 (en) 2013-12-11 2020-10-07 Sloan-kettering Institute For Cancer Research Glucocorticoid inhibitors for treatment of prostate cancer
WO2015136509A2 (en) 2014-03-14 2015-09-17 Genesis Theranostix Korlatolt Felelossegu Tarsasag Diagnostic and therapeutic targets for preeclampsia and closely related complications of pregnancy
US10196701B2 (en) 2015-06-01 2019-02-05 The Penn State Research Foundation Hepatitis B virus capsid assembly
WO2016207313A1 (en) 2015-06-24 2016-12-29 INSERM (Institut National de la Santé et de la Recherche Médicale) Methods and kits for detecting protein-protein interactions
WO2018036503A1 (en) 2016-08-25 2018-03-01 The Chinese University Of Hong Kong Fecal bacterial markers for colorectal cancer
MX2019007030A (es) 2016-12-15 2020-01-15 Univ California Composiciones y metodos para el tratamiento del cancer.
WO2018175324A1 (en) 2017-03-20 2018-09-27 The Broad Institute, Inc. Compounds and methods for regulating insulin secretion
WO2020087107A1 (en) 2018-10-31 2020-05-07 The University Of Sydney Compositions and methods for treating viral infections
WO2020097261A1 (en) 2018-11-06 2020-05-14 The United States Of America As Represented By The Secretary Of The Department Of Health And Human Services New compositions and methods for treating beta-globinopathies
WO2023081167A2 (en) 2021-11-02 2023-05-11 The Regents Of The University Of California P-selectin mutants and modulation of integrin-mediated signaling
WO2023146807A1 (en) 2022-01-25 2023-08-03 The Regents Of The University Of California Vegf mutants and modulation of integrin-mediated signaling

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2010037398A1 (en) * 2008-10-03 2010-04-08 H. Lundbeck A/S Oral formulation
DK55192D0 (da) 1992-04-28 1992-04-28 Lundbeck & Co As H 1-piperazino-1,2-dihydroindenderivater
BRPI0413595B8 (pt) 2003-08-18 2021-05-25 H Lundbeck As sal de malonato, composição farmacêutica, uso de um sal de malonato, e, método de fabricação de um composto
KR20070014184A (ko) * 2004-04-22 2007-01-31 베링거 인겔하임 인터내셔날 게엠베하 성기능 장애 치료용 신규 약제학적 조성물 ⅱ
CN103637977A (zh) 2005-07-18 2014-03-19 宾夕法尼亚大学理事会 含药植入物及其使用方法
BRPI0912223A2 (pt) * 2008-05-07 2015-10-06 Lundbeck & Co As H métodos para melhorar funcionamento cognitivo e para tratar uma doença, composto, uso do mesmo, e, composição farmacêutica.
US8658687B2 (en) 2009-06-24 2014-02-25 Merck Sharp & Dohme Corp. Injectable formulations containing asenapine and method of treatment using same

Similar Documents

Publication Publication Date Title
JP2014517050A5 (US20070167479A1-20070719-C00034.png)
RU2014101482A (ru) Способ применения 4-((1r,3s)-6-хлор-3-фенилиндан-1-ил)-1,2,2-триметилпиперазина и его солей в лечении шизофрении
EP3240538B1 (en) Use of masitinib for treatment of an amyotrophic lateral sclerosis patient subpopulation
US11058638B2 (en) Tyrosine derivatives and compositions comprising them
US20060199805A1 (en) Pharmaceutical compositions for the treatment and/or prevention of anxiety disorders
JP2015512406A5 (US20070167479A1-20070719-C00034.png)
MX344308B (es) Derivados de quinolina carboxamida y quinolina carbonitrilo como moduladores alostericos negativos de mglur2, composiciones y su uso.
JP2014502641A5 (US20070167479A1-20070719-C00034.png)
JP2021080276A (ja) デクスメデトミジン製剤を使用する睡眠障害の予防または治療
JP2011520981A5 (US20070167479A1-20070719-C00034.png)
ES2822562T3 (es) Composiciones intranasales para el tratamiento de enfermedades y trastornos neurológicos y degenerativos
JP2016505050A5 (US20070167479A1-20070719-C00034.png)
JP2019507786A5 (US20070167479A1-20070719-C00034.png)
JP2013536206A5 (US20070167479A1-20070719-C00034.png)
JP2012502105A5 (US20070167479A1-20070719-C00034.png)
TW201211021A (en) Methods of use of cyclic amide derivatives to treat schizophrenia
EP3570841A1 (en) PPARy AGONIST FOR THE TREATMENT OF HUNTINGTON'S DISEASE
JP6420923B1 (ja) 医薬
JP2014037445A (ja) 抵抗性統合失調症およびその他のcns疾患の治療
RU2799049C2 (ru) Способы лечения изменений поведения
KR20200099153A (ko) 외상 후 증후군 장애의 치료
WO2022060978A1 (en) Methods of treating parkinson's disease and related disorders with pde10a inhibitors
WO2020094592A1 (en) Compounds for treating negative symptoms and cognitive impairments
Branch Saskatchewan formulary committee update bulletin to the 55th edition of the Saskatchewan formulary
Consta daivobet gel on pBs