JP2014514248A5 - - Google Patents
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- Publication number
- JP2014514248A5 JP2014514248A5 JP2013554477A JP2013554477A JP2014514248A5 JP 2014514248 A5 JP2014514248 A5 JP 2014514248A5 JP 2013554477 A JP2013554477 A JP 2013554477A JP 2013554477 A JP2013554477 A JP 2013554477A JP 2014514248 A5 JP2014514248 A5 JP 2014514248A5
- Authority
- JP
- Japan
- Prior art keywords
- damage
- animal
- ufa
- vitamin
- nervous system
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
- 230000006378 damage Effects 0.000 claims 25
- 241001465754 Metazoa Species 0.000 claims 16
- 235000021122 unsaturated fatty acids Nutrition 0.000 claims 7
- 150000004670 unsaturated fatty acids Chemical class 0.000 claims 7
- 229930003270 Vitamin B Natural products 0.000 claims 6
- 239000003963 antioxidant agent Substances 0.000 claims 6
- 208000014674 injury Diseases 0.000 claims 6
- 235000019156 vitamin B Nutrition 0.000 claims 6
- 239000011720 vitamin B Substances 0.000 claims 6
- 210000000653 nervous system Anatomy 0.000 claims 5
- 210000004498 neuroglial cell Anatomy 0.000 claims 5
- MWUXSHHQAYIFBG-UHFFFAOYSA-N Nitric oxide Chemical compound O=[N] MWUXSHHQAYIFBG-UHFFFAOYSA-N 0.000 claims 4
- 208000027418 Wounds and injury Diseases 0.000 claims 4
- 239000000203 mixture Substances 0.000 claims 4
- 230000003078 antioxidant effect Effects 0.000 claims 3
- 125000000637 arginyl group Chemical group N[C@@H](CCCNC(N)=N)C(=O)* 0.000 claims 2
- 210000004556 brain Anatomy 0.000 claims 2
- 210000002569 neuron Anatomy 0.000 claims 2
- 210000000278 spinal cord Anatomy 0.000 claims 2
- 230000008733 trauma Effects 0.000 claims 2
- 239000004475 Arginine Substances 0.000 claims 1
- 241000282465 Canis Species 0.000 claims 1
- 241000282324 Felis Species 0.000 claims 1
- AHLPHDHHMVZTML-BYPYZUCNSA-N L-Ornithine Chemical compound NCCC[C@H](N)C(O)=O AHLPHDHHMVZTML-BYPYZUCNSA-N 0.000 claims 1
- RHGKLRLOHDJJDR-BYPYZUCNSA-N L-citrulline Chemical compound NC(=O)NCCC[C@H]([NH3+])C([O-])=O RHGKLRLOHDJJDR-BYPYZUCNSA-N 0.000 claims 1
- 102000006386 Myelin Proteins Human genes 0.000 claims 1
- 108010083674 Myelin Proteins Proteins 0.000 claims 1
- RHGKLRLOHDJJDR-UHFFFAOYSA-N Ndelta-carbamoyl-DL-ornithine Natural products OC(=O)C(N)CCCNC(N)=O RHGKLRLOHDJJDR-UHFFFAOYSA-N 0.000 claims 1
- AHLPHDHHMVZTML-UHFFFAOYSA-N Orn-delta-NH2 Natural products NCCCC(N)C(O)=O AHLPHDHHMVZTML-UHFFFAOYSA-N 0.000 claims 1
- UTJLXEIPEHZYQJ-UHFFFAOYSA-N Ornithine Natural products OC(=O)C(C)CCCN UTJLXEIPEHZYQJ-UHFFFAOYSA-N 0.000 claims 1
- ODKSFYDXXFIFQN-UHFFFAOYSA-N arginine Natural products OC(=O)C(N)CCCNC(N)=N ODKSFYDXXFIFQN-UHFFFAOYSA-N 0.000 claims 1
- 210000001130 astrocyte Anatomy 0.000 claims 1
- 210000003050 axon Anatomy 0.000 claims 1
- 210000004027 cell Anatomy 0.000 claims 1
- 210000005056 cell body Anatomy 0.000 claims 1
- 229960002173 citrulline Drugs 0.000 claims 1
- 235000013477 citrulline Nutrition 0.000 claims 1
- 150000001875 compounds Chemical class 0.000 claims 1
- 210000001787 dendrite Anatomy 0.000 claims 1
- 201000010099 disease Diseases 0.000 claims 1
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 claims 1
- 239000012636 effector Substances 0.000 claims 1
- 235000021323 fish oil Nutrition 0.000 claims 1
- 235000013305 food Nutrition 0.000 claims 1
- 210000000609 ganglia Anatomy 0.000 claims 1
- 230000000968 intestinal effect Effects 0.000 claims 1
- 230000002503 metabolic effect Effects 0.000 claims 1
- 210000000274 microglia Anatomy 0.000 claims 1
- 210000001611 motor endplate Anatomy 0.000 claims 1
- 210000005012 myelin Anatomy 0.000 claims 1
- 239000002417 nutraceutical Substances 0.000 claims 1
- 235000021436 nutraceutical agent Nutrition 0.000 claims 1
- 235000016709 nutrition Nutrition 0.000 claims 1
- 210000004248 oligodendroglia Anatomy 0.000 claims 1
- 235000020660 omega-3 fatty acid Nutrition 0.000 claims 1
- 229960003104 ornithine Drugs 0.000 claims 1
- 210000001428 peripheral nervous system Anatomy 0.000 claims 1
- 210000004116 schwann cell Anatomy 0.000 claims 1
- 210000001057 smooth muscle myoblast Anatomy 0.000 claims 1
- 239000013589 supplement Substances 0.000 claims 1
- 210000000225 synapse Anatomy 0.000 claims 1
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201161463594P | 2011-02-18 | 2011-02-18 | |
| US61/463,594 | 2011-02-18 | ||
| PCT/US2012/024137 WO2012112340A2 (en) | 2011-02-18 | 2012-02-07 | Methods and compositions for treating, reducing, or preventing damage to the nervous system of animals |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2014514248A JP2014514248A (ja) | 2014-06-19 |
| JP2014514248A5 true JP2014514248A5 (cg-RX-API-DMAC7.html) | 2015-03-26 |
Family
ID=46673093
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2013554477A Pending JP2014514248A (ja) | 2011-02-18 | 2012-02-07 | 動物の神経系への損傷を治療、軽減、又は予防するための方法及び組成物 |
Country Status (11)
| Country | Link |
|---|---|
| US (1) | US20130324608A1 (cg-RX-API-DMAC7.html) |
| EP (1) | EP2675447A4 (cg-RX-API-DMAC7.html) |
| JP (1) | JP2014514248A (cg-RX-API-DMAC7.html) |
| CN (1) | CN103764136A (cg-RX-API-DMAC7.html) |
| AU (1) | AU2012218094A1 (cg-RX-API-DMAC7.html) |
| BR (1) | BR112013020802A2 (cg-RX-API-DMAC7.html) |
| CA (1) | CA2827715A1 (cg-RX-API-DMAC7.html) |
| MX (1) | MX2013009544A (cg-RX-API-DMAC7.html) |
| RU (1) | RU2013142437A (cg-RX-API-DMAC7.html) |
| WO (1) | WO2012112340A2 (cg-RX-API-DMAC7.html) |
| ZA (1) | ZA201306990B (cg-RX-API-DMAC7.html) |
Families Citing this family (12)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2014108808A2 (en) * | 2013-01-09 | 2014-07-17 | Henry James Lorne | Pharmaceutical formulations for the treatment and prevention of trauma-induced neuropathology and neurodegeneration |
| US8992951B2 (en) | 2013-01-09 | 2015-03-31 | Sapna Life Sciences Corporation | Formulations, procedures, methods and combinations thereof for reducing or preventing the development, or the risk of development, of neuropathology as a result of trauma |
| US20150328176A1 (en) * | 2013-01-25 | 2015-11-19 | Winning The Fight Inc. | Composition for treatment of neurodegenerative disease |
| CN105828813A (zh) * | 2013-12-19 | 2016-08-03 | 塔索斯·乔治奥 | 涉及治疗神经系统损伤的疾病的ω3脂肪酸组合物 |
| CN104146253A (zh) * | 2014-08-13 | 2014-11-19 | 胡安然 | 癫痫全营养配方食品 |
| WO2018209022A2 (en) * | 2017-05-10 | 2018-11-15 | University Of Rochester | Methods of treating neuropsychiatric disorders |
| CN109300527A (zh) * | 2018-12-14 | 2019-02-01 | 苏州大学 | 饮食信息的推荐方法 |
| US20230016955A1 (en) * | 2020-06-01 | 2023-01-19 | Corona Feed Additives, L.L.C. | Animal Contraceptive |
| JP2023528090A (ja) * | 2020-06-01 | 2023-07-03 | コロナ フィード アディティブス エル．エル．シー． | ブタの避妊組成物、システム及び方法 |
| EP3957316B1 (en) * | 2020-06-16 | 2024-02-07 | MD Healthcare Inc. | Composition for preventing or treating neurological or mental disorders comprising vesicles derived from lactobacillus paracasei |
| CN113368171A (zh) * | 2021-06-18 | 2021-09-10 | 长江大学 | 枸杞在预防放射治疗导致的认知功能障碍药物中的应用 |
| CN113322213B (zh) * | 2021-07-09 | 2022-05-13 | 吉林大学 | 一种具有改善记忆障碍功能的副干酪乳杆菌Jlus66菌剂和应用 |
Family Cites Families (22)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5883087A (en) * | 1991-01-07 | 1999-03-16 | Pherin Corporation | Androstane steroids as neurochemical initiators of change in human hypothalamic function and related pharmaceutical compositions and methods |
| US5308832A (en) * | 1992-07-27 | 1994-05-03 | Abbott Laboratories | Nutritional product for persons having a neurological injury |
| WO1998008500A1 (en) * | 1996-08-26 | 1998-03-05 | Board Of Regents, The University Of Texas System | Hypertonic arginine compositions and methods |
| CA2270795A1 (en) * | 1999-05-05 | 2000-11-05 | Gestilab Inc. | Neuroprotective compositions and uses thereof |
| US7135498B1 (en) * | 1999-06-14 | 2006-11-14 | Henry Ford Health System | Nitric oxide donors for inducing neurogenesis |
| ATE408402T1 (de) * | 1999-06-14 | 2008-10-15 | Ford Henry Health System | Stickstoffmonoxid-donoren zum induzieren von neurogenese |
| US20010036943A1 (en) * | 2000-04-07 | 2001-11-01 | Coe Jotham W. | Pharmaceutical composition for treatment of acute, chronic pain and/or neuropathic pain and migraines |
| US6469049B1 (en) * | 2000-04-21 | 2002-10-22 | The United States Of America As Represented By The Secretary Of The Army | Method of treating, preventing or inhibiting central nervous system injuries and diseases |
| US7563862B2 (en) * | 2001-08-24 | 2009-07-21 | Neuren Pharmaceuticals Limited | Neural regeneration peptides and methods for their use in treatment of brain damage |
| AU2002336638A1 (en) * | 2001-10-12 | 2003-04-28 | Cornell Research Foundation, Inc. | Reversing or preventing premature vascular senescence |
| JP2003261456A (ja) * | 2002-03-08 | 2003-09-16 | Howaizu:Kk | 脳の老化予防剤 |
| US20040186488A1 (en) * | 2003-03-17 | 2004-09-23 | Droese Karl William | Method of peripheral nerve reconstruction using a micro suction connector |
| US6951658B1 (en) * | 2003-07-08 | 2005-10-04 | Pearson Research & Development Limited | Emu-based compositions for mental well-being and method of use |
| CA2598525A1 (en) * | 2005-02-22 | 2006-08-31 | Mochida Pharmaceutical Co., Ltd. | Nerve regeneration promoting agent |
| US20100254951A1 (en) * | 2005-02-22 | 2010-10-07 | Mochida Pharmaceutical Co., Ltd. | Nerve Regeneration Promoting Agent |
| JP2008533005A (ja) * | 2005-03-11 | 2008-08-21 | ヴァーダ コンサルティング リミテッド | 生物学的活性物質の皮内的、経皮的又は経粘膜的送達のための方法 |
| JP2009500040A (ja) * | 2005-07-08 | 2009-01-08 | フイラデルフイア・ヘルス・アンド・エデユケーシヨン・コーポレーシヨン・デイー／ビー／エイ ドレクセルユニバーシテイカレツジオブメデイシン | ニューロンの神経炎症的破壊をモニタリングする方法およびホスホリパーゼａ２に関連する炎症性成分を有する疾患を処置する方法 |
| CA2620024C (en) | 2005-08-26 | 2014-11-18 | Nestec S.A. | Compositions and methods for improving functional vascular integrity, cellular survival and reducing apoptosis in ischemia or after ischemic episode in the brain |
| CN101247736B (zh) * | 2005-08-26 | 2012-11-07 | 雀巢技术公司 | 用于提高功能性血管完整性、细胞存活和在脑中局部缺血或者局部缺血发作后减少程序性细胞死亡的组合物和方法 |
| WO2007050318A2 (en) * | 2005-10-24 | 2007-05-03 | Duke University | Lipidomics approaches for central nervous system disorders |
| RU2500402C2 (ru) * | 2008-01-04 | 2013-12-10 | Нестек С.А. | Композиции, включающие ненасыщенные жирные кислоты и соединения, высбождающие оксид азота, и их применение для усиления когнитивной функции и связанных с ней функций |
| US20090214484A1 (en) * | 2008-02-22 | 2009-08-27 | Nikolay Mironov | Stem cell therapy for the treatment of central nervous system disorders |
-
2012
- 2012-02-07 EP EP12747397.3A patent/EP2675447A4/en not_active Withdrawn
- 2012-02-07 JP JP2013554477A patent/JP2014514248A/ja active Pending
- 2012-02-07 CN CN201280018853.7A patent/CN103764136A/zh active Pending
- 2012-02-07 WO PCT/US2012/024137 patent/WO2012112340A2/en not_active Ceased
- 2012-02-07 CA CA2827715A patent/CA2827715A1/en not_active Abandoned
- 2012-02-07 MX MX2013009544A patent/MX2013009544A/es unknown
- 2012-02-07 BR BR112013020802A patent/BR112013020802A2/pt not_active IP Right Cessation
- 2012-02-07 RU RU2013142437/15A patent/RU2013142437A/ru unknown
- 2012-02-07 US US13/985,884 patent/US20130324608A1/en not_active Abandoned
- 2012-02-07 AU AU2012218094A patent/AU2012218094A1/en not_active Abandoned
-
2013
- 2013-09-17 ZA ZA2013/06990A patent/ZA201306990B/en unknown
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