JP2014512353A5 - - Google Patents

Info

Publication number

JP2014512353A5

JP2014512353A5 JP2014501814A JP2014501814A JP2014512353A5 JP 2014512353 A5 JP2014512353 A5 JP 2014512353A5 JP 2014501814 A JP2014501814 A JP 2014501814A JP 2014501814 A JP2014501814 A JP 2014501814A JP 2014512353 A5 JP2014512353 A5 JP 2014512353A5

Authority

JP

Japan

Prior art keywords

composition according

virus

protein

antiviral composition

pharmaceutical composition

Prior art date

2012-03-05

Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)

Pending

Links

• Espacenet
• Global Dossier
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• 230000000840 anti-viral effect Effects 0.000 claims 7
• 239000000203 mixture Substances 0.000 claims 7
• 108090000623 proteins and genes Proteins 0.000 claims 6
• 102000004169 proteins and genes Human genes 0.000 claims 6
• 239000008194 pharmaceutical composition Substances 0.000 claims 4
• 241000186359 Mycobacterium Species 0.000 claims 3
• 125000003275 alpha amino acid group Chemical group 0.000 claims 2
• 239000004615 ingredient Substances 0.000 claims 2
• 239000000546 pharmaceutical excipient Substances 0.000 claims 2
• 108090000765 processed proteins & peptides Proteins 0.000 claims 2
• 230000001225 therapeutic effect Effects 0.000 claims 2
• FWMNVWWHGCHHJJ-SKKKGAJSSA-N 4-amino-1-[(2r)-6-amino-2-[[(2r)-2-[[(2r)-2-[[(2r)-2-amino-3-phenylpropanoyl]amino]-3-phenylpropanoyl]amino]-4-methylpentanoyl]amino]hexanoyl]piperidine-4-carboxylic acid Chemical compound C([C@H](C(=O)N[C@H](CC(C)C)C(=O)N[C@H](CCCCN)C(=O)N1CCC(N)(CC1)C(O)=O)NC(=O)[C@H](N)CC=1C=CC=CC=1)C1=CC=CC=C1 FWMNVWWHGCHHJJ-SKKKGAJSSA-N 0.000 claims 1
• 208000030507 AIDS Diseases 0.000 claims 1
• 241000725619 Dengue virus Species 0.000 claims 1
• 241000991587 Enterovirus C Species 0.000 claims 1
• 241000711549 Hepacivirus C Species 0.000 claims 1
• 241000700721 Hepatitis B virus Species 0.000 claims 1
• 208000037018 Herpes simplex virus encephalitis Diseases 0.000 claims 1
• 241000710842 Japanese encephalitis virus Species 0.000 claims 1
• 241000712079 Measles morbillivirus Species 0.000 claims 1
• 241001529548 Megasphaera cerevisiae Species 0.000 claims 1
• 241000187479 Mycobacterium tuberculosis Species 0.000 claims 1
• 241000700584 Simplexvirus Species 0.000 claims 1
• 241000725681 Swine influenza virus Species 0.000 claims 1
• 230000021736 acetylation Effects 0.000 claims 1
• 238000006640 acetylation reaction Methods 0.000 claims 1
• 230000000903 blocking effect Effects 0.000 claims 1
• 239000003814 drug Substances 0.000 claims 1
• 230000002401 inhibitory effect Effects 0.000 claims 1
• 238000007918 intramuscular administration Methods 0.000 claims 1
• 238000001990 intravenous administration Methods 0.000 claims 1
• 244000005700 microbiome Species 0.000 claims 1
• 230000006320 pegylation Effects 0.000 claims 1
• 230000026731 phosphorylation Effects 0.000 claims 1
• 238000006366 phosphorylation reaction Methods 0.000 claims 1
• 238000007920 subcutaneous administration Methods 0.000 claims 1
• 230000000699 topical effect Effects 0.000 claims 1
• 230000003612 virological effect Effects 0.000 claims 1