GB2503066A8 - Combination pharmaceutical composition and methods of treating and preventing the infectious diseases - Google Patents

Combination pharmaceutical composition and methods of treating and preventing the infectious diseases Download PDF

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Publication number
GB2503066A8
GB2503066A8 GB1303867.4A GB201303867A GB2503066A8 GB 2503066 A8 GB2503066 A8 GB 2503066A8 GB 201303867 A GB201303867 A GB 201303867A GB 2503066 A8 GB2503066 A8 GB 2503066A8
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United Kingdom
Prior art keywords
treating
preventing
pharmaceutical composition
methods
infectious diseases
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
GB1303867.4A
Other versions
GB2503066B8 (en
GB201303867D0 (en
GB2503066A (en
GB2503066B (en
Inventor
Alexandrovich Tarasov Sergei
Iliich Epshtein Oleg
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Individual
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Individual
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
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Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=45507292&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=GB2503066(A8) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Priority claimed from RU2010133051/15A external-priority patent/RU2505312C2/en
Priority claimed from RU2010133041/15A external-priority patent/RU2010133041A/en
Priority claimed from RU2010133050/15A external-priority patent/RU2502521C2/en
Priority claimed from RU2010133047/15A external-priority patent/RU2517085C2/en
Priority claimed from RU2010133052/15A external-priority patent/RU2500422C2/en
Priority claimed from RU2010133053/15A external-priority patent/RU2521392C2/en
Priority claimed from RU2010133043/15A external-priority patent/RU2519862C2/en
Priority claimed from RU2011127226/15A external-priority patent/RU2577299C2/en
Application filed by Individual filed Critical Individual
Priority to GB1707875.9A priority Critical patent/GB2548034B/en
Publication of GB201303867D0 publication Critical patent/GB201303867D0/en
Publication of GB2503066A publication Critical patent/GB2503066A/en
Application granted granted Critical
Publication of GB2503066B publication Critical patent/GB2503066B/en
Publication of GB2503066A8 publication Critical patent/GB2503066A8/en
Publication of GB2503066B8 publication Critical patent/GB2503066B8/en
Expired - Fee Related legal-status Critical Current
Anticipated expiration legal-status Critical

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Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/28—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
    • C07K16/2803—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against the immunoglobulin superfamily
    • C07K16/2815—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against the immunoglobulin superfamily against CD8
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/395—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/395—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum
    • A61K39/39533—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum against materials from animals
    • A61K39/3955—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum against materials from animals against proteinaceous materials, e.g. enzymes, hormones, lymphokines
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/395—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum
    • A61K39/40—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum bacterial
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/395—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum
    • A61K39/42—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum viral
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K41/00—Medicinal preparations obtained by treating materials with wave energy or particle radiation ; Therapies using these preparations
    • A61K41/0004—Homeopathy; Vitalisation; Resonance; Dynamisation, e.g. esoteric applications; Oxygenation of blood
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/16—Drugs for disorders of the alimentary tract or the digestive system for liver or gallbladder disorders, e.g. hepatoprotective agents, cholagogues, litholytics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A61P11/04—Drugs for disorders of the respiratory system for throat disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A61P31/14—Antivirals for RNA viruses
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A61P31/14—Antivirals for RNA viruses
    • A61P31/16—Antivirals for RNA viruses for influenza or rhinoviruses
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A61P31/14—Antivirals for RNA viruses
    • A61P31/18—Antivirals for RNA viruses for HIV
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A61P31/20—Antivirals for DNA viruses
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/24—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against cytokines, lymphokines or interferons
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/24—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against cytokines, lymphokines or interferons
    • C07K16/241—Tumor Necrosis Factors
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/24—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against cytokines, lymphokines or interferons
    • C07K16/249—Interferons
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/28—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/28—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
    • C07K16/2803—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against the immunoglobulin superfamily
    • C07K16/2812—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against the immunoglobulin superfamily against CD4
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/505—Medicinal preparations containing antigens or antibodies comprising antibodies
    • A61K2039/507—Comprising a combination of two or more separate antibodies
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/70—Immunoglobulins specific features characterized by effect upon binding to a cell or to an antigen
    • C07K2317/76—Antagonist effect on antigen, e.g. neutralization or inhibition of binding

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Immunology (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Molecular Biology (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • Genetics & Genomics (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Engineering & Computer Science (AREA)
  • Virology (AREA)
  • Epidemiology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Microbiology (AREA)
  • Mycology (AREA)
  • Oncology (AREA)
  • Communicable Diseases (AREA)
  • Endocrinology (AREA)
  • Hematology (AREA)
  • Pulmonology (AREA)
  • Alternative & Traditional Medicine (AREA)
  • Otolaryngology (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Biotechnology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • AIDS & HIV (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Peptides Or Proteins (AREA)

Abstract

The present invention relates to a combination pharmaceutical composition comprising a) an activated-potentiated form of an antibody to at least one cytokine and b) an activated-potentiated form of an antibody to at least one receptor, and methods of treating and preventing the infectious diseases, including bacterial infections caused by different infectious agents such as pseudotuberculosis, whooping cough, yersiniosis, pneumonitis of different etiology, and acute and chronic viral infections such as acute respiratory tract infections, influenza of different types, acute viral hepatitis A, B, C and other types of hepatitis, the diseases and conditions caused by HIV or associated with HIV, including AIDS.
GB1303867.4A 2010-08-06 2011-07-15 Combination pharmaceutical composition and methods of treating and preventing the infectious diseases Expired - Fee Related GB2503066B8 (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
GB1707875.9A GB2548034B (en) 2010-08-06 2011-07-15 Combination pharmaceutical composition and methods of treating and preventing the infectious diseases

Applications Claiming Priority (9)

Application Number Priority Date Filing Date Title
RU2010133053/15A RU2521392C2 (en) 2010-08-06 2010-08-06 Combined drug for treating viral infections and method of treating viral infections
RU2010133047/15A RU2517085C2 (en) 2010-08-06 2010-08-06 Complex medication and method of preventing hiv infection, prevention and treatment of hiv-induced and hiv-associated diseases, including aids
RU2010133041/15A RU2010133041A (en) 2010-08-06 2010-08-06 INTEGRATED MEDICINE AND METHOD FOR PREVENTION OF HIV INFECTION, PREVENTION AND TREATMENT OF DISEASES CAUSED BY HIV OR ASSOCIATED WITH HIV, INCLUDING AIDS
RU2010133050/15A RU2502521C2 (en) 2010-08-06 2010-08-06 Combined drug for treating bacterial infections and method of treating bacterial infections
RU2010133051/15A RU2505312C2 (en) 2010-08-06 2010-08-06 Combined therapeutic agent for treating various types of influenza
RU2010133043/15A RU2519862C2 (en) 2010-08-06 2010-08-06 Complex medication and method of prevention and treatment of infectious viral diseases
RU2010133052/15A RU2500422C2 (en) 2010-08-06 2010-08-06 Combined drug for treating viral infections and method of treating viral infections
RU2011127226/15A RU2577299C2 (en) 2011-07-04 2011-07-04 Method for treating infectious diseases and complex medication for treatment of infectious diseases
PCT/IB2011/002470 WO2012017328A2 (en) 2010-08-06 2011-07-15 Combination pharmaceutical composition and methods of treating and preventing the infectious diseases

Publications (5)

Publication Number Publication Date
GB201303867D0 GB201303867D0 (en) 2013-04-17
GB2503066A GB2503066A (en) 2013-12-18
GB2503066B GB2503066B (en) 2017-09-06
GB2503066B8 GB2503066B8 (en) 2019-03-13
GB2503066A8 true GB2503066A8 (en) 2019-03-13

Family

ID=45507292

Family Applications (2)

Application Number Title Priority Date Filing Date
GB1707875.9A Expired - Fee Related GB2548034B (en) 2010-08-06 2011-07-15 Combination pharmaceutical composition and methods of treating and preventing the infectious diseases
GB1303867.4A Expired - Fee Related GB2503066B8 (en) 2010-08-06 2011-07-15 Combination pharmaceutical composition and methods of treating and preventing the infectious diseases

Family Applications Before (1)

Application Number Title Priority Date Filing Date
GB1707875.9A Expired - Fee Related GB2548034B (en) 2010-08-06 2011-07-15 Combination pharmaceutical composition and methods of treating and preventing the infectious diseases

Country Status (19)

Country Link
US (3) US20130045237A1 (en)
EP (1) EP2601219A2 (en)
JP (3) JP2013537532A (en)
KR (1) KR20140012021A (en)
CN (1) CN103154030A (en)
AU (1) AU2011287292B2 (en)
BR (1) BR112013002296A2 (en)
CZ (1) CZ2013159A3 (en)
DE (1) DE112011102640T5 (en)
EA (1) EA030513B1 (en)
ES (1) ES2510940R1 (en)
FR (1) FR2963563A1 (en)
GB (2) GB2548034B (en)
IL (1) IL224545A (en)
MX (1) MX368313B (en)
NZ (1) NZ606993A (en)
PE (1) PE20131185A1 (en)
SG (2) SG187732A1 (en)
WO (1) WO2012017328A2 (en)

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RU2181297C2 (en) * 2000-06-20 2002-04-20 Эпштейн Олег Ильич Method of treatment of pathological syndrome and medicinal agent
UA76638C2 (en) * 2002-08-02 2006-08-15 Oleh Illich Epshtein Homeopathic medication based on anti-interferon antibodies and method for treating a pathological syndrome associated with interferon
RU2309732C1 (en) * 2006-03-13 2007-11-10 Олег Ильич Эпштейн Pressed solid oral formulation of medicinal preparation and method for preparing solid oral formulation of medicinal preparation
SG187038A1 (en) 2010-07-15 2013-02-28 Oleg Iliich Epshtein A method of increasing the effect of an activated-potentiated form of an antibody
CA2804967A1 (en) 2010-07-15 2012-02-09 Oleg Iliich Epshtein Combination pharmaceutical composition and methods of treating diseases or conditions associated with neurodegenerative diseases
MX2013000807A (en) 2010-07-21 2013-10-28 Oleg Iliich Epshtein A method of treating attention deficit hyperactivity disorder.
FR2962909A1 (en) * 2010-07-21 2012-01-27 Oleg Iliich Epshtein PHARMACEUTICAL ASSOCIATION COMPOSITION AND ITS USE IN METHODS FOR TREATING DISEASES OR DISORDERS ASSOCIATED WITH RESPIRATORY DISEASE OR DISEASE
RU2535033C2 (en) * 2010-08-06 2014-12-10 Олег Ильич Эпштейн Therapeutic agent and method for prevention of hiv infection and treatment of hiv-caused or hiv-associated diseases, including aids
JP2013537532A (en) * 2010-08-06 2013-10-03 イリイチ・エプシテイン オレグ Combination pharmaceutical composition and method for treating and preventing infectious diseases
RU2013111961A (en) 2013-03-18 2014-09-27 Олег Ильич Эпштейн METHOD FOR DETERMINING THE EXPRESSION OF MODIFICATION ACTIVITY ASSOCIATED WITH A CARRIER
RU2013111962A (en) 2013-03-18 2014-09-27 Олег Ильич Эпштейн METHOD FOR DETERMINING THE EXPRESSION OF MODIFICATION ACTIVITY ASSOCIATED WITH A CARRIER
RU2603623C2 (en) * 2014-06-06 2016-11-27 Олег Ильич Эпштейн Veterinary composition and method for improving viability of animals, stimulation of body weight gain in mammals and birds, increasing efficiency of immunising, preventing and/or treating infectious diseases (versions)
PT4021505T (en) * 2019-08-29 2024-03-11 Oleg Iliich Epshtein Medicament and method for treating infectious diseases
DE102020007979A1 (en) 2020-12-29 2022-06-30 Charité Universitätsmedizin Institut für Mikrobiologie und Infektionsimmunologie Composition for treating coronavirus infections
WO2023230566A2 (en) * 2022-05-25 2023-11-30 Flagship Pioneering Innovations Vii, Llc Compositions and methods for modulating cytokines
WO2023230249A1 (en) * 2022-05-25 2023-11-30 Baruch S. Blumberg Institute Novel hepatoselective polyadenylating polymerases inhibitors and their method of use

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RU2181297C2 (en) * 2000-06-20 2002-04-20 Эпштейн Олег Ильич Method of treatment of pathological syndrome and medicinal agent
RU2192888C1 (en) 2001-02-15 2002-11-20 Эпштейн Олег Ильич Medicinal agent and method of treatment of pathological syndrome
RU2001134982A (en) * 2001-12-26 2004-02-20 Олег Ильич Эпштейн METHOD OF IMMUNE RESPONSE CORRECTION AND MEDICINE
UA76641C2 (en) 2002-08-02 2006-08-15 Олєг Ільіч Епштєйн Homeopathic medicinal agent and method for curing diseases of prostate
UA76638C2 (en) * 2002-08-02 2006-08-15 Oleh Illich Epshtein Homeopathic medication based on anti-interferon antibodies and method for treating a pathological syndrome associated with interferon
UA76640C2 (en) * 2002-08-02 2006-08-15 Олєг Ільіч Епштєйн Method for correcting pathological immune responses and homeopathic medicinal agent
CA2518965C (en) 2003-03-14 2018-10-30 Nutrition Research Inc. Homeopathic formulations useful for treating pain and/or inflammmation
RU2309732C1 (en) * 2006-03-13 2007-11-10 Олег Ильич Эпштейн Pressed solid oral formulation of medicinal preparation and method for preparing solid oral formulation of medicinal preparation
EA200802440A1 (en) * 2006-06-06 2009-06-30 Олег Ильич ЭПШТЕЙН Drug for the treatment of obesity, diabetes mellitus and diseases with impaired glucose tolerance
WO2008078331A1 (en) * 2006-12-22 2008-07-03 Rajesh Shah Medicinal formulation for the treatment for hepatitis c
RU2332236C1 (en) * 2007-02-02 2008-08-27 Олег Ильич Эпштейн Medicine for bird influenza treatment
CA2804967A1 (en) * 2010-07-15 2012-02-09 Oleg Iliich Epshtein Combination pharmaceutical composition and methods of treating diseases or conditions associated with neurodegenerative diseases
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FR2962909A1 (en) * 2010-07-21 2012-01-27 Oleg Iliich Epshtein PHARMACEUTICAL ASSOCIATION COMPOSITION AND ITS USE IN METHODS FOR TREATING DISEASES OR DISORDERS ASSOCIATED WITH RESPIRATORY DISEASE OR DISEASE
EP2595658A2 (en) * 2010-07-21 2013-05-29 Oleg Iliich Epshtein A combination pharmaceutical composition and methods of treating diabetes and metabolic disorders
EA029998B1 (en) * 2010-07-21 2018-06-29 Олег Ильич ЭПШТЕЙН Combination pharmaceutical composition and method of treatment of vertigo of various genesis, kinetosis and vegetative-vascular dystonia
JP2013537532A (en) * 2010-08-06 2013-10-03 イリイチ・エプシテイン オレグ Combination pharmaceutical composition and method for treating and preventing infectious diseases

Also Published As

Publication number Publication date
EP2601219A2 (en) 2013-06-12
SG10201403870XA (en) 2014-08-28
WO2012017328A2 (en) 2012-02-09
EA030513B1 (en) 2018-08-31
JP2013537532A (en) 2013-10-03
US20130045237A1 (en) 2013-02-21
GB2503066B8 (en) 2019-03-13
GB2548034B (en) 2018-05-23
MX368313B (en) 2019-09-27
AU2011287292A1 (en) 2013-03-14
BR112013002296A2 (en) 2018-01-30
AU2011287292B2 (en) 2017-02-02
MX2013001451A (en) 2013-09-26
GB201303867D0 (en) 2013-04-17
CZ2013159A3 (en) 2013-06-12
US20150023972A1 (en) 2015-01-22
JP2018135370A (en) 2018-08-30
ES2510940R1 (en) 2015-03-27
ES2510940A2 (en) 2014-10-21
PE20131185A1 (en) 2013-10-05
EA201300135A1 (en) 2014-03-31
CN103154030A (en) 2013-06-12
WO2012017328A3 (en) 2012-04-05
GB2548034A (en) 2017-09-06
SG187732A1 (en) 2013-03-28
KR20140012021A (en) 2014-01-29
GB201707875D0 (en) 2017-06-28
DE112011102640T5 (en) 2013-07-11
GB2503066A (en) 2013-12-18
GB2503066B (en) 2017-09-06
JP2016216478A (en) 2016-12-22
FR2963563A1 (en) 2012-02-10
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US20150023980A1 (en) 2015-01-22
IL224545A (en) 2017-11-30

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