JP2014508174A5 - - Google Patents
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- Publication number
- JP2014508174A5 JP2014508174A5 JP2013558168A JP2013558168A JP2014508174A5 JP 2014508174 A5 JP2014508174 A5 JP 2014508174A5 JP 2013558168 A JP2013558168 A JP 2013558168A JP 2013558168 A JP2013558168 A JP 2013558168A JP 2014508174 A5 JP2014508174 A5 JP 2014508174A5
- Authority
- JP
- Japan
- Prior art keywords
- dose
- dose adjustment
- week
- interferon
- adjustment package
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
- 102000014150 Interferons Human genes 0.000 claims 10
- 108010050904 Interferons Proteins 0.000 claims 10
- 229940079322 interferon Drugs 0.000 claims 10
- 238000000034 method Methods 0.000 claims 9
- 206010022004 Influenza like illness Diseases 0.000 claims 4
- 239000003795 chemical substances by application Substances 0.000 claims 3
- RZVAJINKPMORJF-UHFFFAOYSA-N Acetaminophen Chemical group CC(=O)NC1=CC=C(O)C=C1 RZVAJINKPMORJF-UHFFFAOYSA-N 0.000 claims 2
- 208000012266 Needlestick injury Diseases 0.000 claims 2
- 238000002347 injection Methods 0.000 claims 2
- 239000007924 injection Substances 0.000 claims 2
- 239000012669 liquid formulation Substances 0.000 claims 2
- 210000003205 muscle Anatomy 0.000 claims 2
- 229940071643 prefilled syringe Drugs 0.000 claims 2
- 230000002265 prevention Effects 0.000 claims 2
- 206010019233 Headaches Diseases 0.000 claims 1
- 208000008454 Hyperhidrosis Diseases 0.000 claims 1
- HEFNNWSXXWATRW-UHFFFAOYSA-N Ibuprofen Chemical compound CC(C)CC1=CC=C(C(C)C(O)=O)C=C1 HEFNNWSXXWATRW-UHFFFAOYSA-N 0.000 claims 1
- 102000003996 Interferon-beta Human genes 0.000 claims 1
- 108090000467 Interferon-beta Proteins 0.000 claims 1
- 208000000112 Myalgia Diseases 0.000 claims 1
- 206010037660 Pyrexia Diseases 0.000 claims 1
- 230000000202 analgesic effect Effects 0.000 claims 1
- 239000000730 antalgic agent Substances 0.000 claims 1
- 239000002260 anti-inflammatory agent Substances 0.000 claims 1
- 229940121363 anti-inflammatory agent Drugs 0.000 claims 1
- 238000010790 dilution Methods 0.000 claims 1
- 239000012895 dilution Substances 0.000 claims 1
- 229940079593 drug Drugs 0.000 claims 1
- 239000003814 drug Substances 0.000 claims 1
- 206010016256 fatigue Diseases 0.000 claims 1
- 231100000869 headache Toxicity 0.000 claims 1
- 229960001680 ibuprofen Drugs 0.000 claims 1
- 229960001388 interferon-beta Drugs 0.000 claims 1
- 206010025482 malaise Diseases 0.000 claims 1
- 239000000203 mixture Substances 0.000 claims 1
- 201000006417 multiple sclerosis Diseases 0.000 claims 1
- 239000000041 non-steroidal anti-inflammatory agent Substances 0.000 claims 1
- 229940021182 non-steroidal anti-inflammatory drug Drugs 0.000 claims 1
- 229960005489 paracetamol Drugs 0.000 claims 1
- 125000002345 steroid group Chemical group 0.000 claims 1
- 230000035900 sweating Effects 0.000 claims 1
Applications Claiming Priority (5)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201161452807P | 2011-03-15 | 2011-03-15 | |
| US61/452,807 | 2011-03-15 | ||
| US201161476930P | 2011-04-19 | 2011-04-19 | |
| US61/476,930 | 2011-04-19 | ||
| PCT/US2012/029201 WO2012125809A1 (en) | 2011-03-15 | 2012-03-15 | Method for reducing flu-like symptoms associated with intramuscular administration of interferon using a fast titration escalating dosing regimen |
Related Child Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2017170640A Division JP6522069B2 (ja) | 2011-03-15 | 2017-09-05 | 速い用量調節の漸増投与レジメンを用いた、インターフェロンの筋肉内投与に伴うインフルエンザ様症状を軽減するための方法 |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2014508174A JP2014508174A (ja) | 2014-04-03 |
| JP2014508174A5 true JP2014508174A5 (https=) | 2015-04-16 |
| JP6279905B2 JP6279905B2 (ja) | 2018-02-14 |
Family
ID=46045072
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2013558168A Active JP6279905B2 (ja) | 2011-03-15 | 2012-03-15 | 速い用量調節の漸増投与レジメンを用いた、インターフェロンの筋肉内投与に伴うインフルエンザ様症状を軽減するための方法 |
| JP2017170640A Active JP6522069B2 (ja) | 2011-03-15 | 2017-09-05 | 速い用量調節の漸増投与レジメンを用いた、インターフェロンの筋肉内投与に伴うインフルエンザ様症状を軽減するための方法 |
Family Applications After (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2017170640A Active JP6522069B2 (ja) | 2011-03-15 | 2017-09-05 | 速い用量調節の漸増投与レジメンを用いた、インターフェロンの筋肉内投与に伴うインフルエンザ様症状を軽減するための方法 |
Country Status (25)
| Country | Link |
|---|---|
| US (6) | US9198955B2 (https=) |
| EP (1) | EP2686002B1 (https=) |
| JP (2) | JP6279905B2 (https=) |
| KR (1) | KR102050339B1 (https=) |
| CN (1) | CN103702680A (https=) |
| AU (1) | AU2012229104B2 (https=) |
| BR (1) | BR112013023609A8 (https=) |
| CA (1) | CA2846786C (https=) |
| CY (1) | CY1120176T1 (https=) |
| DK (1) | DK2686002T3 (https=) |
| EA (1) | EA028448B1 (https=) |
| ES (1) | ES2666850T3 (https=) |
| HR (1) | HRP20180621T1 (https=) |
| HU (1) | HUE036931T2 (https=) |
| IL (1) | IL228425A (https=) |
| LT (1) | LT2686002T (https=) |
| MX (1) | MX359947B (https=) |
| PL (1) | PL2686002T3 (https=) |
| PT (1) | PT2686002T (https=) |
| RS (1) | RS57175B1 (https=) |
| SG (1) | SG193446A1 (https=) |
| SI (1) | SI2686002T1 (https=) |
| SM (1) | SMT201800221T1 (https=) |
| WO (1) | WO2012125809A1 (https=) |
| ZA (1) | ZA201306933B (https=) |
Families Citing this family (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP2686002B1 (en) * | 2011-03-15 | 2018-01-24 | Biogen Inc. | Method for reducing flu-like symptoms associated with intramuscular administration of interferon using a fast titration escalating dosing regimen |
| EP3092305B1 (en) * | 2014-01-09 | 2023-08-02 | Kyushu University, National University Corporation | Method of producing microglial cells |
| US11266344B2 (en) | 2016-09-21 | 2022-03-08 | Samsung Electronics Co., Ltd. | Method for measuring skin condition and electronic device therefor |
| WO2022069250A1 (en) * | 2020-09-30 | 2022-04-07 | Koninklijke Philips N.V. | Methods and systems for performing dose titration |
Family Cites Families (19)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4456748A (en) | 1981-02-23 | 1984-06-26 | Genentech, Inc. | Hybrid human leukocyte interferons |
| DE3273787D1 (en) | 1981-02-04 | 1986-11-20 | Japan Found Cancer | Human interferon-beta gene |
| US4695543A (en) | 1982-03-23 | 1987-09-22 | Bristol-Myers Company | Alpha Interferon GX-1 |
| CA1302320C (en) | 1984-06-11 | 1992-06-02 | Hideo Niwa | Expression of human cromosomal interferon-_ in animal cells |
| US5231176A (en) | 1984-08-27 | 1993-07-27 | Genentech, Inc. | Distinct family DNA encoding of human leukocyte interferons |
| FI90990C (fi) | 1984-12-18 | 1994-04-25 | Boehringer Ingelheim Int | Rekombinantti-DNA-molekyyli, transformoitu isäntäorganismi ja menetelmä interferonin valmistamiseksi |
| EP0205404B1 (en) | 1985-06-11 | 1992-07-15 | Ciba-Geigy Ag | Hybrid interferons |
| US5641656A (en) | 1993-10-22 | 1997-06-24 | University Of Connecticut | Nucleic acids encoding avian interferon (IFN) proteins and recombinant methods using them |
| TR199901968T2 (xx) * | 1996-12-24 | 1999-12-21 | Biogen, Inc. | Sabit s�v� interferon form�lleri. |
| JP2001104482A (ja) * | 1999-10-07 | 2001-04-17 | Terumo Corp | ２室型プレフィルドシリンジ |
| EP1605992B1 (en) * | 2003-01-30 | 2018-11-21 | Becton, Dickinson and Company | Holder with safety shield for a drug delivery device |
| JP4988562B2 (ja) * | 2004-06-01 | 2012-08-01 | アレス トレーディング ソシエテ アノニム | 安定化したインターフェロン液体製剤 |
| US20060089593A1 (en) * | 2004-10-26 | 2006-04-27 | Sergio Landau | Needle-free injection device for individual users |
| EP1923085A1 (en) * | 2006-11-17 | 2008-05-21 | Sanofi-Aventis Deutschland GmbH | Dosing and drive mechanism for drug delivery device |
| CA2672284C (en) * | 2006-12-18 | 2014-08-26 | Altus Pharmaceuticals Inc. | Human growth hormone formulations |
| US9044378B2 (en) * | 2007-05-31 | 2015-06-02 | Safety Syringes, Inc. | Anti-needle stick safety device or system for use with drugs requiring reconstitution |
| JP5549048B2 (ja) * | 2007-08-16 | 2014-07-16 | 味の素株式会社 | 薬剤バイアルとプレフィルドシリンジの接続構造 |
| JP2012530721A (ja) * | 2009-06-18 | 2012-12-06 | ワイス・エルエルシー | 小モジュール免疫薬のための凍結乾燥製剤 |
| EP2686002B1 (en) * | 2011-03-15 | 2018-01-24 | Biogen Inc. | Method for reducing flu-like symptoms associated with intramuscular administration of interferon using a fast titration escalating dosing regimen |
-
2012
- 2012-03-15 EP EP12719487.6A patent/EP2686002B1/en active Active
- 2012-03-15 HU HUE12719487A patent/HUE036931T2/hu unknown
- 2012-03-15 PT PT127194876T patent/PT2686002T/pt unknown
- 2012-03-15 SG SG2013069018A patent/SG193446A1/en unknown
- 2012-03-15 CN CN201280019863.2A patent/CN103702680A/zh active Pending
- 2012-03-15 EA EA201301024A patent/EA028448B1/ru unknown
- 2012-03-15 JP JP2013558168A patent/JP6279905B2/ja active Active
- 2012-03-15 ES ES12719487.6T patent/ES2666850T3/es active Active
- 2012-03-15 WO PCT/US2012/029201 patent/WO2012125809A1/en not_active Ceased
- 2012-03-15 RS RS20180455A patent/RS57175B1/sr unknown
- 2012-03-15 AU AU2012229104A patent/AU2012229104B2/en active Active
- 2012-03-15 SM SM20180221T patent/SMT201800221T1/it unknown
- 2012-03-15 KR KR1020137027053A patent/KR102050339B1/ko active Active
- 2012-03-15 CA CA2846786A patent/CA2846786C/en active Active
- 2012-03-15 MX MX2013010507A patent/MX359947B/es active IP Right Grant
- 2012-03-15 US US13/421,197 patent/US9198955B2/en active Active
- 2012-03-15 HR HRP20180621TT patent/HRP20180621T1/hr unknown
- 2012-03-15 SI SI201231281T patent/SI2686002T1/en unknown
- 2012-03-15 LT LTEP12719487.6T patent/LT2686002T/lt unknown
- 2012-03-15 DK DK12719487.6T patent/DK2686002T3/en active
- 2012-03-15 BR BR112013023609A patent/BR112013023609A8/pt not_active Application Discontinuation
- 2012-03-15 PL PL12719487T patent/PL2686002T3/pl unknown
-
2013
- 2013-09-12 IL IL228425A patent/IL228425A/en active IP Right Grant
- 2013-09-12 ZA ZA2013/06933A patent/ZA201306933B/en unknown
-
2015
- 2015-11-09 US US14/936,228 patent/US20160101157A1/en not_active Abandoned
-
2017
- 2017-09-05 US US15/695,587 patent/US10500254B2/en active Active
- 2017-09-05 JP JP2017170640A patent/JP6522069B2/ja active Active
-
2018
- 2018-04-23 CY CY20181100424T patent/CY1120176T1/el unknown
-
2019
- 2019-10-22 US US16/660,038 patent/US20200046804A1/en not_active Abandoned
-
2022
- 2022-05-27 US US17/827,282 patent/US20220280610A1/en not_active Abandoned
-
2025
- 2025-05-05 US US19/198,871 patent/US20250276042A1/en active Pending
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