JP2014505108A - 認知機能を改善するための方法および組成物 - Google Patents

認知機能を改善するための方法および組成物 Download PDF

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Publication number
JP2014505108A
JP2014505108A JP2013553575A JP2013553575A JP2014505108A JP 2014505108 A JP2014505108 A JP 2014505108A JP 2013553575 A JP2013553575 A JP 2013553575A JP 2013553575 A JP2013553575 A JP 2013553575A JP 2014505108 A JP2014505108 A JP 2014505108A
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pharmaceutically acceptable
acceptable salt
hydrate
polymorph
solvate
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JP2014505108A5 (enExample
Inventor
ミケラ ギャラガー,
レベッカ ハーバーマン,
ミン テン コー,
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ザ・ジョンズ・ホプキンス・ユニバーシティー
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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/40—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil
    • A61K31/4015—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil having oxo groups directly attached to the heterocyclic ring, e.g. piracetam, ethosuximide
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
    • A61K31/19—Carboxylic acids, e.g. valproic acid
    • A61K31/20—Carboxylic acids, e.g. valproic acid having a carboxyl group bound to a chain of seven or more carbon atoms, e.g. stearic, palmitic, arachidic acids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
    • A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/08—Antiepileptics; Anticonvulsants

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  • Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Neurosurgery (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Organic Chemistry (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Neurology (AREA)
  • Biomedical Technology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Engineering & Computer Science (AREA)
  • Pain & Pain Management (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Steroid Compounds (AREA)
JP2013553575A 2011-02-09 2012-02-09 認知機能を改善するための方法および組成物 Withdrawn JP2014505108A (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201161441251P 2011-02-09 2011-02-09
US61/441,251 2011-02-09
PCT/US2012/024556 WO2012109491A1 (en) 2011-02-09 2012-02-09 Methods and compositions for improving cognitive function

Related Child Applications (1)

Application Number Title Priority Date Filing Date
JP2016132218A Division JP2016172772A (ja) 2011-02-09 2016-07-04 認知機能を改善するための方法および組成物

Publications (2)

Publication Number Publication Date
JP2014505108A true JP2014505108A (ja) 2014-02-27
JP2014505108A5 JP2014505108A5 (enExample) 2015-04-02

Family

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Family Applications (7)

Application Number Title Priority Date Filing Date
JP2013553575A Withdrawn JP2014505108A (ja) 2011-02-09 2012-02-09 認知機能を改善するための方法および組成物
JP2016132218A Withdrawn JP2016172772A (ja) 2011-02-09 2016-07-04 認知機能を改善するための方法および組成物
JP2018060195A Withdrawn JP2018100305A (ja) 2011-02-09 2018-03-27 認知機能を改善するための方法および組成物
JP2020033698A Pending JP2020079318A (ja) 2011-02-09 2020-02-28 認知機能を改善するための方法および組成物
JP2021131734A Pending JP2021175759A (ja) 2011-02-09 2021-08-12 認知機能を改善するための方法および組成物
JP2023119159A Withdrawn JP2023126654A (ja) 2011-02-09 2023-07-21 認知機能を改善するための方法および組成物
JP2025077648A Pending JP2025109773A (ja) 2011-02-09 2025-05-07 認知機能を改善するための方法および組成物

Family Applications After (6)

Application Number Title Priority Date Filing Date
JP2016132218A Withdrawn JP2016172772A (ja) 2011-02-09 2016-07-04 認知機能を改善するための方法および組成物
JP2018060195A Withdrawn JP2018100305A (ja) 2011-02-09 2018-03-27 認知機能を改善するための方法および組成物
JP2020033698A Pending JP2020079318A (ja) 2011-02-09 2020-02-28 認知機能を改善するための方法および組成物
JP2021131734A Pending JP2021175759A (ja) 2011-02-09 2021-08-12 認知機能を改善するための方法および組成物
JP2023119159A Withdrawn JP2023126654A (ja) 2011-02-09 2023-07-21 認知機能を改善するための方法および組成物
JP2025077648A Pending JP2025109773A (ja) 2011-02-09 2025-05-07 認知機能を改善するための方法および組成物

Country Status (9)

Country Link
US (2) US20120214859A1 (enExample)
EP (2) EP2672822A4 (enExample)
JP (7) JP2014505108A (enExample)
CN (2) CN103476255A (enExample)
AU (6) AU2012214303A1 (enExample)
BR (1) BR112013020283A2 (enExample)
CA (1) CA2826765C (enExample)
RU (1) RU2665021C2 (enExample)
WO (1) WO2012109491A1 (enExample)

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US10154988B2 (en) 2012-11-14 2018-12-18 The Johns Hopkins University Methods and compositions for treating schizophrenia
AU2018208662B2 (en) * 2012-11-14 2020-07-23 The Johns Hopkins University Methods and Compositions for Treating Schizophrenia
WO2014144546A1 (en) * 2013-03-15 2014-09-18 The Johns Hopkins University Methods and compositons for improving cognitive function
CA2904767C (en) 2013-03-15 2022-06-21 Agenebio, Inc. Methods and compositions for improving cognitive function
US10806717B2 (en) 2013-03-15 2020-10-20 The Johns Hopkins University Methods and compositions for improving cognitive function
ME03518B (me) 2014-01-21 2020-04-20 Janssen Pharmaceutica Nv Kombinacije koje obuhvataju pozitivne alosterične modulatore ili ortosterične agoniste metabotropnog glutamatergičnog receptora podtipa 2 i njihova primjena
PL3096790T3 (pl) 2014-01-21 2020-01-31 Janssen Pharmaceutica, N.V. Kombinacje zawierające pozytywne modulatory allosteryczne lub agonistów ortosterycznych metabotropowego receptora glutaminergicznego podtypu 2 i ich zastosowanie
EA034167B8 (ru) * 2015-05-22 2021-04-27 Эйджинбайо, Инк. Фармацевтические композиции леветирацетама пролонгированного высвобождения
CN112569216B (zh) * 2019-09-30 2022-02-15 厦门大学 戊酸衍生物在治疗唐氏综合征中的应用
US20250213727A1 (en) 2022-03-25 2025-07-03 Regenxbio Inc. Dominant-negative tumor necrosis factor alpha adeno-associated virus gene therapy
EP4572852A1 (en) 2022-08-19 2025-06-25 Agenebio, Inc. Benzazepine derivatives, compositions, and methods for treating cognitive impairment
CN115517682B (zh) * 2022-11-25 2023-01-31 四川大学华西医院 基于胃肠电信号的认知功能障碍预测系统及构建方法

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Also Published As

Publication number Publication date
AU2016202670A1 (en) 2016-05-19
US20120214859A1 (en) 2012-08-23
CN103476255A (zh) 2013-12-25
RU2013141155A (ru) 2015-03-20
AU2021200325B2 (en) 2022-07-28
JP2025109773A (ja) 2025-07-25
EP2672822A4 (en) 2014-08-27
CA2826765A1 (en) 2012-08-16
EP2672822A1 (en) 2013-12-18
BR112013020283A2 (pt) 2016-07-19
AU2019268069A1 (en) 2019-12-12
AU2012214303A1 (en) 2013-09-12
RU2018129580A3 (enExample) 2022-03-25
JP2018100305A (ja) 2018-06-28
RU2665021C2 (ru) 2018-08-24
EP3400934A1 (en) 2018-11-14
CN109662961A (zh) 2019-04-23
JP2021175759A (ja) 2021-11-04
WO2012109491A1 (en) 2012-08-16
JP2016172772A (ja) 2016-09-29
AU2018201303A1 (en) 2018-03-15
CA2826765C (en) 2021-04-06
AU2022221492A1 (en) 2022-09-22
AU2021200325A1 (en) 2021-03-18
JP2020079318A (ja) 2020-05-28
RU2018129580A (ru) 2019-03-20
US20230033195A1 (en) 2023-02-02
JP2023126654A (ja) 2023-09-07

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