JP2014500307A5 - - Google Patents

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Publication number
JP2014500307A5
JP2014500307A5 JP2013545584A JP2013545584A JP2014500307A5 JP 2014500307 A5 JP2014500307 A5 JP 2014500307A5 JP 2013545584 A JP2013545584 A JP 2013545584A JP 2013545584 A JP2013545584 A JP 2013545584A JP 2014500307 A5 JP2014500307 A5 JP 2014500307A5
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agent
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JP2013545584A
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Japanese (ja)
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JP5992435B2 (ja
JP2014500307A (ja
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Priority claimed from PCT/IB2011/055730 external-priority patent/WO2012085789A1/en
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Publication of JP2014500307A5 publication Critical patent/JP2014500307A5/ja
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JP2013545584A 2010-12-21 2011-12-16 循環からの生体分子の除去剤 Active JP5992435B2 (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
EP10196092.0 2010-12-21
EP10196092 2010-12-21
PCT/IB2011/055730 WO2012085789A1 (en) 2010-12-21 2011-12-16 Agents for clearing biomolecules from circulation

Publications (3)

Publication Number Publication Date
JP2014500307A JP2014500307A (ja) 2014-01-09
JP2014500307A5 true JP2014500307A5 (enExample) 2015-10-29
JP5992435B2 JP5992435B2 (ja) 2016-09-14

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ID=43530614

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2013545584A Active JP5992435B2 (ja) 2010-12-21 2011-12-16 循環からの生体分子の除去剤

Country Status (6)

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US (1) US9427482B2 (enExample)
EP (1) EP2654796A1 (enExample)
JP (1) JP5992435B2 (enExample)
CN (1) CN103328008B (enExample)
RU (1) RU2013133813A (enExample)
WO (1) WO2012085789A1 (enExample)

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US20160151505A1 (en) 2011-05-16 2016-06-02 Koninklijke Philips N.V. Bio-orthogonal drug activation
WO2014081299A1 (en) * 2012-11-22 2014-05-30 Tagworks Pharmaceuticals B.V. Activatable liposomes
US20150297741A1 (en) * 2012-11-22 2015-10-22 Tagworks Pharmaceuticals B.V. Bio-orthogonal drug activation
EP4245744A3 (en) * 2012-11-22 2024-05-01 Tagworks Pharmaceuticals B.V. Chemically cleavable group
WO2014081300A1 (en) * 2012-11-22 2014-05-30 Tagworks Pharmaceuticals B.V. Channel protein activatable liposomes
EP3010486B1 (en) 2013-06-19 2023-11-22 The Regents of The University of California Chemical structures for localized delivery of therapeutic agents
WO2015139025A1 (en) 2014-03-14 2015-09-17 The Regents Of The University Of California Tco conjugates and methods for delivery of therapeutic agents
WO2016025480A1 (en) 2014-08-11 2016-02-18 The General Hospital Corporation Cyclooctenes for bioorthogonol reactions
HRP20211864T1 (hr) 2015-07-06 2022-03-04 Alkermes, Inc. Inhibitori hetero-halo histonske deacetilaze
EP3319968A1 (en) 2015-07-06 2018-05-16 Rodin Therapeutics, Inc. Heterobicyclic n-aminophenyl-amides as inhibitors of histone deacetylase
JP6823067B2 (ja) 2015-09-10 2021-01-27 タンボ・インコーポレイテッド 生体直交型組成物
US11617799B2 (en) * 2016-06-27 2023-04-04 Tagworks Pharmaceuticals B.V. Cleavable tetrazine used in bio-orthogonal drug activation
US10222346B2 (en) * 2017-01-09 2019-03-05 National Research Council Of Canada Decomposable S-tetrazine based polymers for single walled carbon nanotube applications
KR102526032B1 (ko) 2017-01-11 2023-04-25 로딘 테라퓨틱스, 인크. 히스톤 데아세틸라제의 바이시클릭 억제제
AU2018250312C1 (en) 2017-04-07 2024-08-22 Tambo, Inc. Bioorthogonal compositions
CA3069140A1 (en) * 2017-07-06 2019-01-10 Memorial Sloan Kettering Cancer Center Dota-hapten compositions for anti-dota/anti-tumor antigen bispecific antibody pretargeted radioimmunotherapy
EP3651741A4 (en) 2017-07-14 2021-04-21 The Penn State Research Foundation Compositions and methods for targeted delivery of therapeutic and/or diagnostic species
SI3664802T1 (sl) 2017-08-07 2022-10-28 Alkermes, Inc. Biciklični zaviralci histon deacetilaze
US20210017295A1 (en) 2018-03-12 2021-01-21 Memorial Sloan Kettering Cancer Center Bispecific binding agents and uses thereof
TWI827677B (zh) 2018-09-18 2024-01-01 美商尼坎醫療公司 作為src同源-2磷酸酶抑制劑之稠合三環衍生物
IL289095A (en) 2019-06-17 2022-02-01 Tagworks Pharmaceuticals B V Activating components to cleave labels from biomolecules in vivo
CN115135628A (zh) 2019-06-17 2022-09-30 泰克沃尔科斯制药有限公司 快速高效点击释放的化合物
AU2024220523B2 (en) * 2023-02-15 2025-12-11 Tagworks Pharmaceuticals B.V. Tetrazines with improved properties
WO2025166249A1 (en) * 2024-01-31 2025-08-07 Oregon State University Tetrazine amino acids and methods for their production and use

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