JP2014500307A5 - - Google Patents

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JP2014500307A5
JP2014500307A5 JP2013545584A JP2013545584A JP2014500307A5 JP 2014500307 A5 JP2014500307 A5 JP 2014500307A5 JP 2013545584 A JP2013545584 A JP 2013545584A JP 2013545584 A JP2013545584 A JP 2013545584A JP 2014500307 A5 JP2014500307 A5 JP 2014500307A5
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agent
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JP2013545584A
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Japanese (ja)
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JP5992435B2 (ja
JP2014500307A (ja
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Priority claimed from PCT/IB2011/055730 external-priority patent/WO2012085789A1/en
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JP2013545584A 2010-12-21 2011-12-16 循環からの生体分子の除去剤 Active JP5992435B2 (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
EP10196092.0 2010-12-21
EP10196092 2010-12-21
PCT/IB2011/055730 WO2012085789A1 (en) 2010-12-21 2011-12-16 Agents for clearing biomolecules from circulation

Publications (3)

Publication Number Publication Date
JP2014500307A JP2014500307A (ja) 2014-01-09
JP2014500307A5 true JP2014500307A5 (enExample) 2015-10-29
JP5992435B2 JP5992435B2 (ja) 2016-09-14

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JP2013545584A Active JP5992435B2 (ja) 2010-12-21 2011-12-16 循環からの生体分子の除去剤

Country Status (6)

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US (1) US9427482B2 (enExample)
EP (1) EP2654796A1 (enExample)
JP (1) JP5992435B2 (enExample)
CN (1) CN103328008B (enExample)
RU (1) RU2013133813A (enExample)
WO (1) WO2012085789A1 (enExample)

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US10927139B2 (en) 2012-11-22 2021-02-23 Tagworks Pharmaceuticals B.V. Chemically cleavable group
WO2014081300A1 (en) * 2012-11-22 2014-05-30 Tagworks Pharmaceuticals B.V. Channel protein activatable liposomes
WO2014081299A1 (en) * 2012-11-22 2014-05-30 Tagworks Pharmaceuticals B.V. Activatable liposomes
US20150297741A1 (en) * 2012-11-22 2015-10-22 Tagworks Pharmaceuticals B.V. Bio-orthogonal drug activation
EP3010486B1 (en) 2013-06-19 2023-11-22 The Regents of The University of California Chemical structures for localized delivery of therapeutic agents
AU2015229014B2 (en) 2014-03-14 2019-07-25 The Regents Of The University Of California TCO conjugates and methods for delivery of therapeutic agents
WO2016025480A1 (en) 2014-08-11 2016-02-18 The General Hospital Corporation Cyclooctenes for bioorthogonol reactions
WO2017007755A1 (en) 2015-07-06 2017-01-12 Rodin Therapeutics, Inc. Heterobicyclic n-aminophenyl-amides as inhibitors of histone deacetylase
HUE057041T2 (hu) 2015-07-06 2022-04-28 Alkermes Inc Hiszton deacetiláz hetero-halogén gátlói
CN108135857A (zh) 2015-09-10 2018-06-08 沙思奇公司 生物正交组合物
US11617799B2 (en) * 2016-06-27 2023-04-04 Tagworks Pharmaceuticals B.V. Cleavable tetrazine used in bio-orthogonal drug activation
US10222346B2 (en) * 2017-01-09 2019-03-05 National Research Council Of Canada Decomposable S-tetrazine based polymers for single walled carbon nanotube applications
HRP20220223T1 (hr) 2017-01-11 2022-04-29 Alkermes, Inc. Biciklički inhibitori histon deacetilaze
AU2018250312C1 (en) 2017-04-07 2024-08-22 Tambo, Inc. Bioorthogonal compositions
ES3057687T3 (en) 2017-07-06 2026-03-04 Memorial Sloan Kettering Cancer Center Dota-hapten compositions for anti-dota/anti-tumor antigen bispecific antibody pretargeted radioimmunotherapy
EP3651741A4 (en) 2017-07-14 2021-04-21 The Penn State Research Foundation COMPOSITIONS AND METHODS OF TARGETED DELIVERY OF A THERAPEUTIC AND / OR DIAGNOSTIC SPECIES
US11225475B2 (en) 2017-08-07 2022-01-18 Alkermes, Inc. Substituted pyridines as inhibitors of histone deacetylase
CN112088169A (zh) 2018-03-12 2020-12-15 纪念斯隆凯特琳癌症中心 双特异性结合剂及其用途
JP7337174B2 (ja) 2018-09-18 2023-09-01 ニカング セラピューティクス， インコーポレイテッド Ｓｒｃホモロジー－２ホスファターゼ阻害剤としての三置換ヘテロアリール誘導体
WO2020247151A1 (en) * 2019-06-05 2020-12-10 Boston Scientific Scimed, Inc. Click chemistry capturable platinum-based antineoplastic agents
WO2020256546A1 (en) 2019-06-17 2020-12-24 Tagworks Pharmaceuticals B.V. Compounds for fast and efficient click release
CA3143924C (en) 2019-06-17 2025-06-03 Tagworks Pharmaceuticals B.V. Agents that allow in vivo cleavage of markers linked to biomolecules
JP2023537066A (ja) 2020-08-07 2023-08-30 タンボ・インコーポレイテッド トランス－シクロオクテン生体直交型薬剤並びに癌及び免疫療法における使用
KR20250141267A (ko) * 2023-02-15 2025-09-26 태그웍스 파마슈티컬스 비.브이. 개선된 특성을 가지는 테트라진
WO2025166249A1 (en) * 2024-01-31 2025-08-07 Oregon State University Tetrazine amino acids and methods for their production and use

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