JP2014054391A - Biological information processing apparatus, holter electrocardiograph, and biological information processing system - Google Patents

Abstract

PROBLEM TO BE SOLVED: To provide a biological information processing apparatus, a Holter electrocardiograph, and a biological information processing system that predict and analyze abnormality of the heart of a cardiac disease patient and presents a report on the results.SOLUTION: Configured as follows is a workstation 40 that analyzes monitoring electrocardiographic waveforms, or the electrocardiographic waveforms collected by a Holter electrocardiograph 20 attached to a subject who has undergone treatment of a cardiac disease: The workstation 40 comprises: database 42 in which electrocardiographic waveforms of the subject in normal conditions are stored; operation part 44 which compares the monitoring electrocardiographic waveforms and the electrocardiographic waveforms in normal conditions, extracts abnormal waveforms in the monitoring electrocardiographic waveforms, and identifies the part of the heart and the blood vessel which causes the abnormal waveforms on the basis of the abnormal waveforms; and a control part 41 which controls the operation part 44.

Description

  Embodiments described herein relate generally to a biological information processing apparatus, a Holter electrocardiograph, and a biological information processing system that process information collected from a living body.

  Conventionally, there has been known a network system that monitors the electrocardiogram waveform of a heart disease patient such as angina pectoris or myocardial infarction and notifies the hospital / analysis center of the abnormality when the electrocardiogram waveform is abnormal. It has been.

  When this network system is used, a diagnosis is made based on the electrocardiogram information at the hospital / analysis center that is notified that an abnormality has occurred, and a notification that prompts the patient to visit (emergency delivery to the hospital) Contact).

  For example, a method disclosed in Patent Document 1 is known as a technique for analyzing an electrocardiographic waveform as described above and a technique relating to the creation of an analysis report thereof.

JP 2010-233953 A

  By the way, the network system as described above becomes a response after an abnormality actually occurs in the patient's heart due to its configuration. Therefore, even if the electrocardiogram waveform is constantly monitored, for example, when a seizure or a serious condition occurs, it is of course very difficult to avoid worsening the situation.

  In addition, although various methods have been proposed for the analysis method of the electrocardiogram waveform, the conventional analysis method is generally referred to as a heart disease patient and a person after heart disease treatment (hereinafter simply referred to as “cardiac disease patient”). It is not considered that the normal electrocardiogram waveform of () is different from the normal electrocardiogram waveform of a person who is not a heart disease patient. Therefore, when a conventional analysis method is used, there is a possibility that the electrocardiogram waveform of a heart disease patient is always determined to be an abnormal waveform.

  The present invention has been made in view of the above circumstances, and predicts and analyzes abnormalities of the heart of a patient with heart disease and presents a detailed report about them, a biological information processing apparatus, a Holter electrocardiograph, and biological information An object is to provide a processing system.

The biological information processing apparatus according to one embodiment
A biological information processing apparatus for analyzing a monitoring electrocardiographic waveform, which is an electrocardiographic waveform collected by a Holter electrocardiograph attached to a subject who has undergone treatment for heart disease,
A database in which normal ECG waveforms that are normal ECG waveforms of the subject are recorded;
Comparing the monitoring electrocardiogram waveform and the normal electrocardiogram waveform, and extracting an abnormal waveform of the monitoring electrocardiogram waveform;
Based on the abnormal waveform, the abnormal part and blood vessel specifying part for specifying the heart part and blood vessel that are the cause of the abnormal waveform,
A report creation unit for creating an abnormality report indicating a result of identification by the abnormal part and the blood vessel identification unit;
It is characterized by comprising.

A Holter electrocardiograph according to one embodiment
A Holter electrocardiograph that is attached to a subject who has undergone treatment for heart disease and transmits the collected electrocardiogram waveform to a predetermined biological information processing apparatus,
A recording unit in which a normal electrocardiogram waveform that is a normal electrocardiogram waveform of the subject is recorded;
A sensor unit for collecting a monitoring electrocardiogram waveform which is an electrocardiogram waveform of the subject;
Comparing the normal ECG waveform recorded in the recording unit with the monitoring ECG waveform collected by the sensor unit, and detecting an abnormality in the monitoring ECG waveform;
A communication unit that transmits the detection result and the electrocardiogram waveform to the predetermined biological information processing apparatus when an abnormality is detected by the abnormality detection unit;
It is characterized by comprising.

A biological information processing system according to an embodiment includes:
A biological information processing system comprising: a Holter electrocardiograph attached to a subject who has undergone treatment for a heart disease; and a biological information processing apparatus for analyzing a monitoring electrocardiographic waveform that is an electrocardiographic waveform collected by the Holter electrocardiograph Because
The Holter electrocardiograph is
A recording unit in which a normal electrocardiogram waveform that is a normal electrocardiogram waveform of the subject is recorded;
A sensor unit for collecting a monitoring electrocardiogram waveform for the subject;
Comparing the normal ECG waveform recorded in the recording unit with the monitoring ECG waveform collected by the sensor unit, and detecting an abnormality in the monitoring ECG waveform;
A transmission unit that transmits the detection result and the monitoring electrocardiogram waveform to the predetermined biological information processing apparatus when an abnormality is detected by the abnormality detection unit;
Have
The biological information processing apparatus includes:
A database in which normal ECG waveforms that are normal ECG waveforms of the subject are recorded;
A receiving unit for receiving the monitoring electrocardiogram waveform;
Comparing the monitoring electrocardiogram waveform received by the receiving unit with the normal electrocardiogram waveform, and extracting an abnormal waveform from the monitoring electrocardiogram waveform;
Based on the abnormal waveform, an abnormal site specifying unit for specifying a cardiac site and a blood vessel that are the cause of the abnormal waveform,
A report creation unit for creating an abnormality report indicating the identification result by the abnormal site identification unit;
It is characterized by having.

FIG. 1 is a diagram illustrating a configuration example of a biological information processing system according to the present embodiment. FIG. 2 is a block diagram showing a detailed configuration of the Holter electrocardiograph and WS. FIG. 3 is a diagram illustrating a flowchart of an example of processing performed by the biological information processing system according to the present embodiment. FIG. 4 is a flowchart of the subroutines of steps S5 and S6. FIG. 5 is a diagram illustrating an example of the report image. FIG. 6 is a diagram showing a concept unique to the biological information processing system according to this modification.

  Hereinafter, a biological information processing apparatus, a Holter electrocardiograph, and a biological information processing system according to an embodiment of the present invention will be described.

  FIG. 1 is a diagram illustrating a configuration example of a biological information processing system according to the present embodiment. As shown in the figure, the biological information processing system includes a Holter electrocardiograph 20 worn by a heart disease patient, an electrocardiograph 30 connected to a hospital network 10 and a workstation (hereinafter abbreviated as WS). 40 and a database (hereinafter abbreviated as DB) 50. In the figure, a Holter electrocardiograph 20 'connected to the in-hospital network 10 is a Holter electrocardiograph when a heart disease patient visits a hospital.

  The Holter electrocardiograph 20 is a Holter electrocardiograph provided with a wireless electrocardiogram and configured to collect all 12 lead waveforms. This Holter electrocardiograph 20 is attached to a heart disease patient using the biological information processing system according to the present embodiment. The detailed configuration of the Holter electrocardiograph 20 will be described later with reference to FIG.

  The electrocardiograph 30 is an electrocardiograph for acquiring a normal electrocardiographic waveform (hereinafter referred to as a normal electrocardiographic waveform) after the operation of the heart disease patient. The normal singular electrocardiogram waveform acquired by the electrocardiograph 30 is stored in the DB 50.

  The WS 40 is a workstation (biological information processing apparatus) that performs analysis and image processing on the monitoring electrocardiogram waveform transmitted from the Holter electrocardiograph 20. Specific processing by the WS 40 will be described in detail later.

  The DB 50 includes electrocardiogram information including a monitoring electrocardiogram waveform transmitted from the Holter electrocardiograph 20, normal singular electrocardiogram waveforms acquired by the electrocardiograph 30, various images, basic data used for abnormal waveform analysis, and “heart This is a database for recording “data used for radio wave shape analysis processing / image processing”.

  It is assumed that at least the normal time specific electrocardiogram waveform acquired by the electrocardiograph 30 is recorded in the DB 50 at the time of starting the monitoring of the electrocardiogram waveform at the home of the heart disease patient (outside the hospital).

  FIG. 2 is a block diagram showing a detailed configuration of the Holter electrocardiograph 20 and the WS 40. As shown in the figure, the Holter electrocardiograph 20 includes a sensor unit 22 for acquiring an electrocardiogram waveform of the heart disease patient, and a main body 21 for recording and analyzing a measurement result by the sensor unit 22. Have. The main body 21 includes a control unit 23, a storage unit 24, a communication unit 25, a calculation unit 26, a display unit 27, and a sensor reception unit 28.

  The sensor unit 22 is a measurement unit for collecting electrocardiographic waveforms of the heart disease patient. Hereinafter, the electrocardiographic waveform acquired by the measurement by the sensor unit 22 is referred to as “monitoring electrocardiographic waveform”.

  The control unit 23 comprehensively controls each part of the Holter electrocardiograph 20.

  The storage unit 24 is a recording medium that records a monitoring electrocardiogram waveform acquired by the sensor unit 22. Prior to monitoring by the Holter electrocardiograph 20, the normal singular electrocardiogram waveform of the heart disease patient is supplied from the WS 40 to the Holter electrocardiograph 20 and recorded in the storage unit 24.

  The communication unit 25 is a communication unit for transmitting a monitoring electrocardiogram waveform and an abnormality analysis result to the WS 40 when an abnormality is detected in the electrocardiogram waveform of the heart disease patient.

  The calculation unit 26 compares the monitoring electrocardiogram waveform collected by the sensor unit 22 with the normal singular electrocardiogram waveform recorded in the storage unit 24 (performs an abnormality analysis), and based on the result. Abnormality determination (details will be described later) is executed. In other words, the calculation unit 26 extracts an abnormal waveform from the monitoring electrocardiogram waveform acquired by the sensor unit 22 and determines the degree of abnormality of the abnormal waveform.

  The display unit 27 is a display for presenting various information such as the result of the abnormality analysis and additional information to the heart disease patient.

  The sensor receiving unit 28 is a receiving unit for receiving monitoring electrocardiographic waveforms collected by the sensor unit 22 from the sensor unit 22 via wireless / wired communication means.

  Incidentally, the WS 40 includes a control unit 41, a storage unit 42, a communication unit 43, a calculation unit 44, and a display unit 45, as shown in FIG.

  The control unit 41 comprehensively controls each unit of the WS 40.

  The storage unit 42 stores the normal singular electrocardiogram waveform, the monitoring electrocardiogram waveform, the basic data used for the abnormal waveform analysis, the “data used for the electrocardiogram waveform analysis processing / image processing, etc.”, etc. , Acquired from the DB 50 and temporarily recorded.

  Further, an “abnormal waveform template” is recorded in the storage unit 42 in advance. This “abnormal waveform template” is a template for estimating an abnormality type (specific disease) and an abnormal part based on a waveform pattern.

  The communication unit 43 is a communication unit for transmitting and receiving data to and from the Holter electrocardiograph 20.

  The calculation unit 44 performs various numerical calculations / image processing calculations such as analysis of a monitoring electrocardiogram waveform and extraction of a site / blood vessel causing an abnormality (hereinafter abbreviated as an abnormal cause site / blood vessel). Do.

  The display unit 45 is a display unit that displays the analysis result by the calculation unit 44, various data such as an abnormal cause region / blood vessel extraction image, a diagnostic image, and various information such as a report image (details will be described later).

  Hereinafter, with reference to FIG. 3, an example of processing by the biological information processing system according to the present embodiment will be described. FIG. 3 is a diagram illustrating a flowchart of an example of processing performed by the biological information processing system according to the present embodiment.

  First, an electrocardiogram waveform (that is, the normal singular electrocardiogram waveform described above) is acquired for a postoperative heart disease patient by the electrocardiograph 30 in the hospital, and the normal singular electrocardiogram waveform is stored in the DB 50 and WS 40 in the hospital. It records in the memory | storage part 42 and the memory | storage part 24 of the Holter electrocardiograph 20 (step S1).

  Since the postoperative heart is in a state in which some of its functions are lost, even if it is a normal electrocardiogram, it becomes a unique electrocardiogram specific to each patient. Therefore, in the biological information processing system according to the present embodiment, the normal singular electrocardiogram is used as a reference for monitoring the post-operative electrocardiogram. Step S1 is a step in which an electrocardiographic waveform serving as a reference is acquired and recorded in advance.

  Here, the normal singular electrocardiogram waveform may be transferred from the electrocardiograph 30 via the in-hospital network 10 to the DB 50 in the hospital. As for the Holter electrocardiograph 20, as in the Holter electrocardiograph 20 ′ shown in FIG. 1, once connected to the in-hospital network 10, a normal singular electrocardiogram waveform is transferred from the electrocardiograph 30 via the in-hospital network 10. Good.

  In the biological information processing system according to the present embodiment, the Holter electrocardiograph 20 acquires a normal singular electrocardiogram waveform from the WS 40 at the start time of the electrocardiogram waveform monitoring at the heart disease patient's home (outside the hospital), It is premised on recording in the storage unit 24.

  Subsequently, under the control of the control unit 23 of the Holter electrocardiograph 20 attached to the heart disease patient, the sensor unit 22 starts measuring the electrocardiogram waveform of the heart disease patient, and collects and stores a monitoring electrocardiogram waveform. Recording to 24 is started (step S2).

  Note that the collection of the monitoring electrocardiogram waveform may be performed in a time zone as necessary, for example, it may be performed constantly (24 hours).

  After the collection of the monitoring electrocardiogram waveform is started in step S2, the calculation unit 26 starts an analysis and abnormality determination of the monitoring electrocardiogram waveform under the control of the control unit 23 (step S3).

  In this abnormality analysis, the calculation unit 26 compares the monitoring electrocardiogram waveform collected by the sensor unit 22 with the normal singular electrocardiogram waveform recorded in the storage unit 24, and the comparison calculation result (matching degree ( According to the degree of difference)), it is determined whether an abnormality corresponding to “no abnormality”, “abnormal abnormality”, or “urgent abnormality” has occurred, and will be described later An abnormal prediction is also made.

  Specifically, the calculation unit 26 uses the normal singular electrocardiogram waveform as a reference, compares this with the monitoring electrocardiogram waveform, and extracts a difference between them. If there is a difference between the waveforms, a waveform related to the difference (abnormal waveform) is extracted. Further, the arithmetic unit 26 compares the extracted abnormal waveform with an “abnormal waveform template” registered in the storage unit 24 in advance, and based on the waveform pattern, the presence / absence of abnormality and the type of abnormality (emergency Etc.).

  Further, in step S3, in parallel with the above-described abnormality analysis, the monitoring electrocardiogram waveform and the template of the “abnormal reserve group waveform (the heart in the time zone slightly before the time zone in which the abnormality actually occurs) The waveform analysis is performed to determine whether or not the state corresponds to the abnormal reserve group. As described above, by using the “abnormal preliminary group waveform template” instead of the “abnormal waveform template”, it is possible to detect the state before the abnormality occurs (abnormal prediction).

  When it is determined in step S3 that “no abnormality”, the control unit 23 performs control so as to continue the abnormality analysis and abnormality determination of the collected monitoring electrocardiogram waveform.

  If it is determined in step S3 that “there is an abnormality (regardless of the presence or absence of urgency)”, the control unit 23 controls the communication unit 25 to display the corresponding monitoring electrocardiogram waveform and the abnormality analysis result by the calculation unit 26. It transmits to WS40 in a hospital (step S4A). At this time, the control unit 23 may control the display unit 27 to display a message stating “There is a non-urgent abnormality”.

  If it is determined in step S3 that there is an “abnormality of urgency”, the processing in step S4A described above is performed, and the control unit 23 informs that fact by a heart disease patient wearing the Holter electrocardiograph 20 Control to notify to (step S4B). Specifically, as this notification method, for example, a method of displaying “an urgent abnormality has occurred” on the display unit 27 or a speaker (not shown) included in the Holter electrocardiograph 20 is displayed. A method of generating a “notifying voice” can be mentioned.

  It should be noted that also when occurrence of an abnormality is predicted by waveform analysis using the “abnormal preliminary group waveform template” in step S3, the process branches to step S4B. At this time, examples of the message displayed on the display unit 27 include a message indicating that “it may fall into danger”.

  By the way, the WS 40 in the hospital receives the monitoring electrocardiogram waveform and the abnormality analysis result transmitted from the Holter electrocardiograph 20 in the step S4A by the communication unit 43. And the control part 41 performs a detailed abnormality analysis about the said monitoring electrocardiogram waveform by the calculating part 44 (step S5), and performs extraction (specification) of abnormality cause site | part / blood vessel (step S6).

  FIG. 4 is a flowchart of the subroutines of steps S5 and S6. Here, with reference to FIG. 4, the process in step S5 and step S6 is demonstrated in detail. Steps S5-1 to S5-3 shown in FIG. 4 are processes corresponding to Step S5 in FIG. 3, and Steps S6-1 to S6-3 shown in FIG. 4 correspond to Step S6 in FIG. It is processing.

  First, the calculation unit 44 extracts a waveform for one heartbeat from the normal singular electrocardiogram waveform of the heart disease patient, and compares the extracted waveform with a normal waveform (for a person who is not a heart disease patient). Then, a portion having a low similarity (single waveform region) is extracted and set as a “specific waveform region template” of the heart disease patient (step S5-1). A conventional technique may be used as a method for calculating the similarity.

  Note that data obtained by extracting and analyzing a plurality of waveforms from the normal ECG waveform of the heart disease patient and taking the average value thereof may be used as a “specific waveform region (template)”. Furthermore, instead of executing the processing at the time of the processing in step S5, processing is performed in advance to generate a “singular waveform region template” and recorded in the storage unit 24 of the Holter electrocardiograph 20 and the storage unit 42 of the WS 40. You may keep it.

  Subsequently, the calculation unit 44 extracts a waveform for one heartbeat from the monitoring electrocardiogram waveform, compares it with the “specific waveform region template” set in step S5-1 (or in advance), and sets the “singular waveform region”. A corresponding region other than “excluding” is extracted as an “analysis target region” (step S5-2).

  In step S5-2, the monitoring electrocardiogram waveform is checked to see if there is a wavelength expansion or contraction in the heartbeat interval due to the delay in transmission of electrical stimulation. Comparison with templates corresponding to diseases that cause wavelength stretching.

  After that, the calculation unit 44 compares the “analysis target region” waveform extracted in step S5-2 with the “cardiac disease electrocardiogram waveform template (template indicating an electrocardiogram waveform abnormal due to heart disease)”. Then, the similarity between the two is calculated, and it is determined whether or not the similarity exceeds the “designated similarity” (step S5-3). This similarity is an index indicating that the higher the value is (the more similar the both waveforms are), the higher the degree of abnormality that is occurring.

  When step S5-3 is branched to NO, the control unit 41 determines “no abnormality / follow-up” for the disease corresponding to the “disease electrocardiogram waveform template”, and in step S5-3, another control is performed. The same processing is performed for the “disease electrocardiogram waveform template”.

  When step S5-3 is branched to YES, the control unit 41 determines that there is “abnormality” related to the disease corresponding to the “cardiac electrocardiogram waveform template”, and the calculation unit 44 uses the 12 of the monitoring electrocardiogram waveform. A specific abnormal part is specified with reference to the induced waveform (step S6-1).

  Specifically, in step S6-1, the waveform for one heartbeat of the monitoring electrocardiogram is analyzed using each limb / chest induction waveform to estimate which part of the left / right atrium / ventricle is abnormal. To do. Specifically, since each limb / chest induction waveform is determined from which direction of the heart, the expansion of each waveform, the change in vector direction (for example, positive / negative reversal, etc.), and the waveform signal Based on the intensity (myocardial mass or myocardial activity) or the like, either the left or right atrium / ventricle is specified as a place where an abnormality is estimated.

  In addition, by considering the position of the electrode to be worn by the heart disease patient and comprehensively evaluating a plurality of induced waveforms, not only the four categories of left and right atrium / ventricle but also the distance between the electrodes and the intensity of the waveform signal Based on the analysis, for example, the left and right ventricles may be analyzed to “left ventricular” / “right ventricular” and presented in addition to the estimation result. Furthermore, the waveform may be analyzed using the waveform of the stimulus conduction system, and the location may be specified in more detail.

  Subsequently, the control unit 41 extracts the region (abnormal cause site) identified in Step S6-1 in the medical image acquired in the past for the heart disease patient by the calculation unit 44, and further, blood vessels ( An abnormal cause blood vessel is extracted (step S6-2). An existing technique may be used for the “region extraction” and “automatic blood vessel extraction” in step S6-2. For example, the control unit 41 uses the existing medical diagnostic image (for example, CT image, MR image, ultrasonic diagnostic image, etc.) of the heart disease patient stored in the DB 50 by the calculation unit 44 to perform the image processing. What is necessary is just to extract the blood vessel which nourishes an abnormal part and an abnormal part.

  Then, the control unit 41 estimates the “degree of abnormality” based on the intensity of the monitored electrocardiogram waveform, the degree of delay, the change in waveform shape (the rise degree of the ST wave), etc. (Step S6-3). Whether or not to notify the doctor / heart disease patient of this “degree of abnormality” may be determined based on the estimation result.

  For example, when the degree of abnormality is high, a doctor / cardiac disease patient is notified to prompt early reexamination, and when the degree of abnormality is low, notification that follow-up is necessary may be made. Furthermore, when an abnormality has occurred in an existing diseased part or an existing follow-up observation target part, the “degree of abnormality” may be set higher than the case where it is not.

  If an abnormality requiring urgent occurrence has occurred, a “notification to that effect” and a “message for prompting a visit” may be automatically notified to the Holter electrocardiograph 20.

  By the way, in the storage unit 24 of the Holter electrocardiograph 20 and the storage unit 42 of the WS 40, the monitoring electrocardiogram waveform in a time zone slightly before the time zone in which an abnormality actually occurs is displayed as an “abnormal preliminary group waveform template”. Record as.

  By using this “abnormal preliminary group waveform template” for the abnormality analysis in steps S3 and S5, the state of the abnormal preliminary group (the state similar to the state in which an abnormality has occurred (the previous stage)) is detected and notified. That is, for example, in parallel with the above-described abnormality analysis in step S3, the monitoring electrocardiogram waveform and “abnormal reserve group waveform template” are compared and calculated to perform waveform analysis as to whether or not the abnormal reserve group is satisfied. Here, if the waveform corresponds to the abnormal reserve group waveform, for example, “notification that there is a possibility of falling into danger” is displayed on the display unit 27 to notify the heart disease patient.

  By the way, after completing the process in step S6, the control unit 41 creates an image (hereinafter referred to as a report image) that presents information including the abnormal site / blood vessel extracted in step S6 and causes the display unit 45 to display the image. (Step S7).

  FIG. 5 is a diagram showing a configuration example of the report image created and displayed in step S7. As shown in the figure, the report image 145 includes a first portion 101 that displays a normal singular electrocardiogram waveform (a waveform collected before the start of monitoring) and a monitoring electrocardiogram waveform (abnormal waveform). 2 part 103, a third part 105 for displaying the heart image of the person acquired at the time of the previous surgery, and a fourth part 107 for displaying the 12-lead ECG waveform transmitted from the Holter electrocardiograph 20 Have. Here, in the fourth portion 107, the reexamination image 111 newly acquired when the heart disease patient revisits is superimposed on the 12-lead ECG waveform (or replaced with the 12-lead ECG waveform). ) May be displayed.

  Here, examples of the heart image displayed on the first portion 101 include arbitrary rendering images such as 2D images, 3D images, and CPR images. A desired heart image may be used as required by the operator.

  In the display of the normal singular electrocardiogram waveform in the first portion 101 and the display of the monitoring electrocardiogram waveform in the second portion 103, the waveform portion where the abnormality actually occurs on the display is referred to as the other portion. It is displayed so that it can be easily identified (for example, colored (in the example shown in FIG. 5, a shaded portion)).

  Although not shown, “numerical information” may be presented as an analysis result in the report image 145.

  After the WS 40 displays the above-described report image 145 on the display unit 45 in step S7, the doctor makes a comprehensive diagnosis with reference to the report image 145. Here, if it is diagnosed that there is an abnormality and an input operation to that effect is performed by the doctor, the control unit 41 of the WS 40 causes the communication unit 43 to visit the Holter electrocardiograph 20 so as to visit the patient with the heart disease. Send a message.

  This message is received by the communication unit 25 of the Holter electrocardiograph 20 and displayed on the display unit 27 under the control of the control unit 23. Thereafter, when the heart disease patient visits and performs image diagnosis again, the newly acquired heart image is associated with various information used in the report image 145 of the heart disease patient in association with the DB 50. Or the like, and may be used as the reexamination image 111 shown in FIG. 5 when the next report image 145 is created.

  As described above, according to the present embodiment, a biological information processing apparatus, a Holter electrocardiograph, and a biological information processing system that predict and analyze heart abnormalities of heart disease patients and present detailed reports about them Can be provided.

  That is, according to the biological information processing apparatus, the Holter electrocardiograph, and the biological information processing system according to the present embodiment, based on the monitoring electrocardiogram collected by the Holter electrocardiograph attached to the heart disease patient, the heart disease patient When an abnormality has occurred / highly likely to occur in the heart of the patient, the state of the previous stage of the abnormality / abnormality is detected and automatically notified to the hospital, and the cause of the abnormality based on the monitoring electrocardiogram waveform A site / blood vessel is identified, and a report image showing the identification result is created.

  In this report image, the abnormal site estimated based on the monitoring electrocardiogram waveform and the blood vessel that is likely to be the cause are estimated, and the abnormal cause site / blood vessel is displayed together with the electrocardiogram waveform using the existing person's heart image. To do. When reexamination is performed, the heart image acquired by the reexamination is displayed together with the past image, and the abnormal cause site / blood vessel is clearly shown on the display.

  In the above-described embodiment, an electrocardiogram waveform (heartbeat waveform) is assumed as the biological information to be processed. However, within the range in which the gist of the above-described embodiment is not changed, But of course it can be applied.

<Modification>
The above-described embodiment can be used by being modified as follows, for example. In order to avoid duplication of explanation, differences from the one embodiment will be described.

  FIG. 6 is a diagram showing a concept unique to the biological information processing system according to this modification. As shown in the figure, in this modification, a Holter electrocardiograph 20-1 further provided with an “acceleration sensor” and a “position sensor” is attached to a heart disease patient P.

  In the Holter electrocardiograph 20-1, the control unit 23 controls the communication unit 25 to obtain the position information of the heart disease patient P acquired by the acceleration sensor and the position information acquired by the position sensor in the WS 40 in the hospital H. (Step S101). This transmission may be periodic automatic transmission, for example.

  The control unit 41 of the WS 40 determines the necessity of the heart disease patient P to visit based on the body position information and position information transmitted from the Holter electrocardiograph 20-1. When it is determined that a visit is necessary, the control unit 41 transmits a “message requesting a visit” to the Holter electrocardiograph 20-1 by the communication unit 43 (step S102).

  If no response is received from the heart disease patient P within a certain period after the processing in step S102 is completed (step S103), it is assumed that the heart disease patient P cannot move by itself. . Therefore, in this case, the control unit 41 notifies the rescue request to the family of the heart disease patient P or the hospital H (step S104). Thereby, the said heart disease patient P will be conveyed to a hospital by an ambulance etc. (step S105).

  Although one embodiment of the present invention has been described, this one embodiment is presented as an example and is not intended to limit the scope of the invention. The new embodiment can be implemented in various other forms, and various omissions, replacements, and changes can be made without departing from the scope of the invention. The one embodiment and its modifications are included in the scope and gist of the invention, and are also included in the invention described in the claims and the equivalents thereof.

    DESCRIPTION OF SYMBOLS 10 ... Hospital network, 20, 20-1 ... Holter electrocardiograph, 21 ... Main body, 22 ... Sensor unit, 23 ... Control part, 24 ... Memory | storage part, 25 ... Communication part, 26 ... Calculation part, 27 ... Display part, 28 DESCRIPTION OF SYMBOLS ... Sensor receiving part, 40 ... Workstation, 41 ... Control part, 42 ... Memory | storage part, 43 ... Communication part, 44 ... Calculation part, 45 ... Display part, 50 ... Database, 145 ... Report image.

Claims (7)

A biological information processing apparatus for analyzing a monitoring electrocardiographic waveform, which is an electrocardiographic waveform collected by a Holter electrocardiograph attached to a subject who has undergone treatment for heart disease,
A database in which normal ECG waveforms that are normal ECG waveforms of the subject are recorded;
Comparing the monitoring electrocardiogram waveform and the normal electrocardiogram waveform, and extracting an abnormal waveform of the monitoring electrocardiogram waveform;
Based on the abnormal waveform, the abnormal part and blood vessel specifying part for specifying the heart part and blood vessel that are the cause of the abnormal waveform,
A report creation unit for creating an abnormality report indicating a result of identification by the abnormal part and the blood vessel identification unit;
A biological information processing apparatus comprising: The report creation unit
Creating an abnormality report that associates the abnormal waveform extracted by the abnormal waveform extraction unit with the cardiac region and blood vessel identified as the cause of the abnormal waveform by the abnormal region and blood vessel specifying unit; The biological information processing apparatus according to claim 1. A Holter electrocardiograph that is attached to a subject who has undergone treatment for heart disease and transmits the collected electrocardiogram waveform to a predetermined biological information processing apparatus,
A recording unit in which a normal electrocardiogram waveform that is a normal electrocardiogram waveform of the subject is recorded;
A sensor unit for collecting a monitoring electrocardiogram waveform which is an electrocardiogram waveform of the subject;
Comparing the normal ECG waveform recorded in the recording unit with the monitoring ECG waveform collected by the sensor unit, and detecting an abnormality in the monitoring ECG waveform;
A communication unit that transmits the detection result and the electrocardiogram waveform to the predetermined biological information processing apparatus when an abnormality is detected by the abnormality detection unit;
A Holter electrocardiograph characterized by comprising: An acceleration sensor that detects the posture of the subject and generates posture information;
A position sensor that detects the position of the subject and generates position information;
Including
The Holter electrocardiograph according to claim 3, wherein the communication unit transmits the body position information and the position information to the predetermined biological information processing apparatus. When an abnormality is detected by the abnormality detection unit, an urgency determination unit that determines urgency for the abnormality, and
When it is determined that urgency is required by the urgency determination unit, an urgency notification unit that notifies the subject to that effect,
The Holter electrocardiograph according to claim 3, comprising: A biological information processing system comprising: a Holter electrocardiograph attached to a subject who has undergone treatment for a heart disease; and a biological information processing apparatus for analyzing a monitoring electrocardiographic waveform that is an electrocardiographic waveform collected by the Holter electrocardiograph Because
The Holter electrocardiograph is
A recording unit in which a normal electrocardiogram waveform that is a normal electrocardiogram waveform of the subject is recorded;
A sensor unit for collecting a monitoring electrocardiogram waveform for the subject;
Comparing the normal ECG waveform recorded in the recording unit with the monitoring ECG waveform collected by the sensor unit, and detecting an abnormality in the monitoring ECG waveform;
A transmission unit that transmits the detection result and the monitoring electrocardiogram waveform to the predetermined biological information processing apparatus when an abnormality is detected by the abnormality detection unit;
Have
The biological information processing apparatus includes:
A database in which normal ECG waveforms that are normal ECG waveforms of the subject are recorded;
A receiving unit for receiving the monitoring electrocardiogram waveform;
Comparing the monitoring electrocardiogram waveform received by the receiving unit with the normal electrocardiogram waveform, and extracting an abnormal waveform from the monitoring electrocardiogram waveform;
Based on the abnormal waveform, an abnormal site specifying unit for specifying a cardiac site and a blood vessel that are the cause of the abnormal waveform,
A report creation unit for creating an abnormality report indicating the identification result by the abnormal site identification unit;
A biological information processing system characterized by comprising: The Holter electrocardiograph is
An acceleration sensor that detects the posture of the subject and generates posture information;
A position sensor that detects the position of the subject and generates position information;
A sensor information transmission unit for transmitting the body position information and the position information to the predetermined biological information processing apparatus;
Including
The biological information processing apparatus includes:
A sensor information receiver that receives the body position information and the position information transmitted from the sensor information transmitter;
A determination unit that determines whether an abnormality has occurred in the subject based on the body position information and the position information;
The biological information processing system according to claim 6, comprising:

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