JP2013538813A5 - - Google Patents
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- Publication number
- JP2013538813A5 JP2013538813A5 JP2013527303A JP2013527303A JP2013538813A5 JP 2013538813 A5 JP2013538813 A5 JP 2013538813A5 JP 2013527303 A JP2013527303 A JP 2013527303A JP 2013527303 A JP2013527303 A JP 2013527303A JP 2013538813 A5 JP2013538813 A5 JP 2013538813A5
- Authority
- JP
- Japan
- Prior art keywords
- seq
- antibody
- binding
- antigen
- vegfr
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
- 239000000427 antigen Substances 0.000 claims 9
- 102000036639 antigens Human genes 0.000 claims 9
- 108091007433 antigens Proteins 0.000 claims 9
- 101000851030 Homo sapiens Vascular endothelial growth factor receptor 3 Proteins 0.000 claims 7
- 101000851029 Mus musculus Vascular endothelial growth factor receptor 3 Proteins 0.000 claims 6
- 239000008194 pharmaceutical composition Substances 0.000 claims 2
- FWMNVWWHGCHHJJ-SKKKGAJSSA-N 4-amino-1-[(2r)-6-amino-2-[[(2r)-2-[[(2r)-2-[[(2r)-2-amino-3-phenylpropanoyl]amino]-3-phenylpropanoyl]amino]-4-methylpentanoyl]amino]hexanoyl]piperidine-4-carboxylic acid Chemical compound C([C@H](C(=O)N[C@H](CC(C)C)C(=O)N[C@H](CCCCN)C(=O)N1CCC(N)(CC1)C(O)=O)NC(=O)[C@H](N)CC=1C=CC=CC=1)C1=CC=CC=C1 FWMNVWWHGCHHJJ-SKKKGAJSSA-N 0.000 claims 1
- 239000003085 diluting agent Substances 0.000 claims 1
- 239000003814 drug Substances 0.000 claims 1
- 239000003937 drug carrier Substances 0.000 claims 1
- 239000004615 ingredient Substances 0.000 claims 1
- 239000000203 mixture Substances 0.000 claims 1
- 239000000546 pharmaceutical excipient Substances 0.000 claims 1
- 230000001225 therapeutic effect Effects 0.000 claims 1
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US38043210P | 2010-09-07 | 2010-09-07 | |
| US61/380,432 | 2010-09-07 | ||
| PCT/US2011/050131 WO2012033696A1 (en) | 2010-09-07 | 2011-09-01 | Anti-vegfr-3 antibody compositions |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2013538813A JP2013538813A (ja) | 2013-10-17 |
| JP2013538813A5 true JP2013538813A5 (enExample) | 2014-05-08 |
Family
ID=44584686
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2013527303A Pending JP2013538813A (ja) | 2010-09-07 | 2011-09-01 | 抗ｖｅｇｆｒ−３抗体組成物 |
Country Status (26)
| Country | Link |
|---|---|
| US (2) | US8481034B2 (enExample) |
| EP (1) | EP2614081B1 (enExample) |
| JP (1) | JP2013538813A (enExample) |
| KR (1) | KR20130042601A (enExample) |
| CN (1) | CN103080133A (enExample) |
| AR (1) | AR082641A1 (enExample) |
| AU (1) | AU2011299443B2 (enExample) |
| BR (1) | BR112013005423A2 (enExample) |
| CA (1) | CA2809375C (enExample) |
| CL (1) | CL2013000607A1 (enExample) |
| CO (1) | CO6690754A2 (enExample) |
| CR (1) | CR20130065A (enExample) |
| DO (1) | DOP2013000039A (enExample) |
| EA (1) | EA023331B1 (enExample) |
| EC (1) | ECSP13012481A (enExample) |
| ES (1) | ES2568801T3 (enExample) |
| GT (1) | GT201300058A (enExample) |
| MA (1) | MA34487B1 (enExample) |
| MX (1) | MX2013002718A (enExample) |
| PE (1) | PE20131328A1 (enExample) |
| PH (1) | PH12013500432A1 (enExample) |
| SG (1) | SG188265A1 (enExample) |
| TW (1) | TWI413527B (enExample) |
| UA (1) | UA109148C2 (enExample) |
| WO (1) | WO2012033696A1 (enExample) |
| ZA (1) | ZA201300804B (enExample) |
Families Citing this family (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2014064203A1 (en) | 2012-10-26 | 2014-05-01 | INSERM (Institut National de la Santé et de la Recherche Médicale) | Lyve-1 antagonists for preventing or treating a pathological condition associated with lymphangiogenesis |
| KR101521981B1 (ko) * | 2013-07-31 | 2015-05-20 | 가톨릭대학교 산학협력단 | 혈액암 줄기세포 증식 또는 생착 억제용 조성물 |
| EP3244924B1 (en) * | 2015-01-15 | 2021-04-07 | Oncoquest Pharmaceuticals Inc. | Methods of increasing delivery of anti-cancer agents to targets |
| CA3044682A1 (en) | 2016-12-02 | 2018-06-07 | University Of Southern California | Synthetic immune receptors and methods of use thereof |
| CN110004167A (zh) * | 2019-04-16 | 2019-07-12 | 中国医学科学院血液病医院（血液学研究所） | 靶向vegfr-2和/或vegfr-3嵌合抗原受体及其应用 |
| CN111808191A (zh) * | 2020-05-11 | 2020-10-23 | 廊坊天光生物技术有限公司 | 一种用于检测血清中vegf含量的抗体对及其用途 |
Family Cites Families (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| AU2002248372B8 (en) * | 2001-01-19 | 2008-03-20 | Vegenics Limited | FLT4(VEGFR-3) as a target for tumor imaging and anti-tumor therapy |
| CN101277976B (zh) | 2005-10-06 | 2012-04-11 | 伊莱利利公司 | 抗肌抑制素抗体 |
-
2011
- 2011-08-25 AR ARP110103100A patent/AR082641A1/es unknown
- 2011-08-26 TW TW100130812A patent/TWI413527B/zh not_active IP Right Cessation
- 2011-09-01 US US13/223,344 patent/US8481034B2/en active Active
- 2011-09-01 EA EA201390117A patent/EA023331B1/ru not_active IP Right Cessation
- 2011-09-01 JP JP2013527303A patent/JP2013538813A/ja active Pending
- 2011-09-01 CN CN2011800430574A patent/CN103080133A/zh active Pending
- 2011-09-01 EP EP11754805.7A patent/EP2614081B1/en active Active
- 2011-09-01 SG SG2013013107A patent/SG188265A1/en unknown
- 2011-09-01 ES ES11754805.7T patent/ES2568801T3/es active Active
- 2011-09-01 CA CA2809375A patent/CA2809375C/en not_active Expired - Fee Related
- 2011-09-01 MA MA35695A patent/MA34487B1/fr unknown
- 2011-09-01 KR KR1020137005794A patent/KR20130042601A/ko not_active Ceased
- 2011-09-01 BR BR112013005423A patent/BR112013005423A2/pt not_active IP Right Cessation
- 2011-09-01 UA UAA201302462A patent/UA109148C2/uk unknown
- 2011-09-01 WO PCT/US2011/050131 patent/WO2012033696A1/en not_active Ceased
- 2011-09-01 AU AU2011299443A patent/AU2011299443B2/en not_active Ceased
- 2011-09-01 PE PE2013000380A patent/PE20131328A1/es not_active Application Discontinuation
- 2011-09-01 MX MX2013002718A patent/MX2013002718A/es unknown
- 2011-09-01 PH PH1/2013/500432A patent/PH12013500432A1/en unknown
-
2013
- 2013-01-30 ZA ZA2013/00804A patent/ZA201300804B/en unknown
- 2013-02-14 DO DO2013000039A patent/DOP2013000039A/es unknown
- 2013-02-15 CR CR20130065A patent/CR20130065A/es unknown
- 2013-03-04 CL CL2013000607A patent/CL2013000607A1/es unknown
- 2013-03-05 GT GT201300058A patent/GT201300058A/es unknown
- 2013-03-06 EC ECSP13012481 patent/ECSP13012481A/es unknown
- 2013-03-07 CO CO13046124A patent/CO6690754A2/es unknown
- 2013-05-07 US US13/888,716 patent/US8784818B2/en not_active Expired - Fee Related
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