JP2013524213A5 - - Google Patents
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- Publication number
- JP2013524213A5 JP2013524213A5 JP2013502539A JP2013502539A JP2013524213A5 JP 2013524213 A5 JP2013524213 A5 JP 2013524213A5 JP 2013502539 A JP2013502539 A JP 2013502539A JP 2013502539 A JP2013502539 A JP 2013502539A JP 2013524213 A5 JP2013524213 A5 JP 2013524213A5
- Authority
- JP
- Japan
- Prior art keywords
- sample
- complement activation
- human
- assay
- complex
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
- 238000003556 assay Methods 0.000 claims 6
- 230000024203 complement activation Effects 0.000 claims 6
- 101000725508 Homo sapiens Cartilage oligomeric matrix protein Proteins 0.000 claims 3
- 210000002808 connective tissue Anatomy 0.000 claims 3
- 201000010099 disease Diseases 0.000 claims 3
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 claims 3
- 102000050578 human COMP Human genes 0.000 claims 3
- 230000002757 inflammatory effect Effects 0.000 claims 3
- 201000001320 Atherosclerosis Diseases 0.000 claims 2
- 208000024172 Cardiovascular disease Diseases 0.000 claims 2
- 201000009594 Systemic Scleroderma Diseases 0.000 claims 2
- 206010042953 Systemic sclerosis Diseases 0.000 claims 2
- 208000000491 Tendinopathy Diseases 0.000 claims 2
- 206010043255 Tendonitis Diseases 0.000 claims 2
- 230000000295 complement effect Effects 0.000 claims 2
- 238000006731 degradation reaction Methods 0.000 claims 2
- 239000012634 fragment Substances 0.000 claims 2
- 239000003446 ligand Substances 0.000 claims 2
- 201000004415 tendinitis Diseases 0.000 claims 2
- 230000008354 tissue degradation Effects 0.000 claims 2
- 206010061818 Disease progression Diseases 0.000 claims 1
- 208000003456 Juvenile Arthritis Diseases 0.000 claims 1
- 206010059176 Juvenile idiopathic arthritis Diseases 0.000 claims 1
- 201000001263 Psoriatic Arthritis Diseases 0.000 claims 1
- 208000036824 Psoriatic arthropathy Diseases 0.000 claims 1
- 201000002661 Spondylitis Diseases 0.000 claims 1
- 239000007864 aqueous solution Substances 0.000 claims 1
- 230000001684 chronic effect Effects 0.000 claims 1
- 230000005750 disease progression Effects 0.000 claims 1
- 238000005259 measurement Methods 0.000 claims 1
- 239000000203 mixture Substances 0.000 claims 1
- 238000012544 monitoring process Methods 0.000 claims 1
- 210000002966 serum Anatomy 0.000 claims 1
- 239000007787 solid Substances 0.000 claims 1
- 239000000243 solution Substances 0.000 claims 1
- 210000001179 synovial fluid Anatomy 0.000 claims 1
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| SE1050310 | 2010-03-31 | ||
| SE1050310-0 | 2010-03-31 | ||
| PCT/SE2011/050369 WO2011123044A1 (en) | 2010-03-31 | 2011-03-30 | Method to detect tissue degradation leading to inflammation |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2013524213A JP2013524213A (ja) | 2013-06-17 |
| JP2013524213A5 true JP2013524213A5 (https=) | 2014-05-08 |
Family
ID=44712493
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2013502539A Pending JP2013524213A (ja) | 2010-03-31 | 2011-03-30 | 炎症をもたらす組織分解を検出する方法 |
Country Status (5)
| Country | Link |
|---|---|
| US (1) | US20130084584A1 (https=) |
| EP (1) | EP2553465A4 (https=) |
| JP (1) | JP2013524213A (https=) |
| AU (1) | AU2011233753A1 (https=) |
| WO (1) | WO2011123044A1 (https=) |
Families Citing this family (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP3771468A1 (en) * | 2019-07-31 | 2021-02-03 | Universitätsklinikum Hamburg-Eppendorf | C3/c5 convertase assays |
Family Cites Families (11)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4342566A (en) * | 1980-02-22 | 1982-08-03 | Scripps Clinic & Research Foundation | Solid phase anti-C3 assay for detection of immune complexes |
| US4642284A (en) * | 1983-06-13 | 1987-02-10 | Scripps Clinic And Research Foundation | Method and system for detection of complement pathway activation |
| SE452065B (sv) * | 1986-04-11 | 1987-11-09 | Ulf R Nilsson | Antikroppspreparation vars antikroppar er specifika for determinanter i c3 b regionen hos denaturerat humant c3 samt dess anvendning och framstellning |
| IL84160A0 (en) * | 1986-10-16 | 1988-03-31 | Vasocor | Method and kit for immune complex assay |
| KR20000064637A (ko) * | 1996-03-19 | 2000-11-06 | 에프.지.엠. 헤르만스 | 비(b)형 간염의 감염 결과를 예측하는 방법 |
| SE9904236D0 (sv) * | 1999-11-22 | 1999-11-22 | Ana Mar Diagnostics Ab | Immunoassay |
| CA2502926A1 (en) * | 2002-11-08 | 2004-05-27 | Linda J. Sandell | Uncoupled collagen synthesis and degradation assays |
| ES2360804T3 (es) * | 2004-05-24 | 2011-06-09 | Anamar Ab | Método para determinar un proceso de degradación tisular mediante la detección de neoepítopos de comp. |
| BRPI0812767A2 (pt) * | 2007-06-07 | 2014-12-02 | Genentech Inc | Anticorpos para c3b e métodos para prevenção e tratamento de distúrbios associados ao complemento |
| CA2690568A1 (en) * | 2007-06-20 | 2008-12-24 | Schering Corporation | Joint destruction biomarkers for anti-il-17a therapy of inflammatory joint disease |
| EP3112379A1 (en) * | 2008-03-21 | 2017-01-04 | Universiteit Hasselt | Biomarkers for rheumatoid arthritis |
-
2011
- 2011-03-30 JP JP2013502539A patent/JP2013524213A/ja active Pending
- 2011-03-30 AU AU2011233753A patent/AU2011233753A1/en not_active Abandoned
- 2011-03-30 US US13/636,145 patent/US20130084584A1/en not_active Abandoned
- 2011-03-30 EP EP11763156.4A patent/EP2553465A4/en not_active Withdrawn
- 2011-03-30 WO PCT/SE2011/050369 patent/WO2011123044A1/en not_active Ceased
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