JP2013518574A5 - - Google Patents
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- JP2013518574A5 JP2013518574A5 JP2012551627A JP2012551627A JP2013518574A5 JP 2013518574 A5 JP2013518574 A5 JP 2013518574A5 JP 2012551627 A JP2012551627 A JP 2012551627A JP 2012551627 A JP2012551627 A JP 2012551627A JP 2013518574 A5 JP2013518574 A5 JP 2013518574A5
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- 210000004027 cell Anatomy 0.000 claims 29
- 238000000034 method Methods 0.000 claims 21
- 108010077544 Chromatin Proteins 0.000 claims 6
- 210000003483 chromatin Anatomy 0.000 claims 6
- 210000004962 mammalian cell Anatomy 0.000 claims 6
- 239000000523 sample Substances 0.000 claims 6
- 241000124008 Mammalia Species 0.000 claims 5
- 201000010099 disease Diseases 0.000 claims 4
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 claims 4
- LSNNMFCWUKXFEE-UHFFFAOYSA-M Bisulfite Chemical compound OS([O-])=O LSNNMFCWUKXFEE-UHFFFAOYSA-M 0.000 claims 3
- 102100024263 CD160 antigen Human genes 0.000 claims 3
- 238000006243 chemical reaction Methods 0.000 claims 3
- 206010012601 diabetes mellitus Diseases 0.000 claims 3
- 239000003814 drug Substances 0.000 claims 3
- 229940079593 drug Drugs 0.000 claims 3
- 239000002243 precursor Substances 0.000 claims 3
- 102100035248 Alpha-(1,3)-fucosyltransferase 4 Human genes 0.000 claims 2
- 102100024222 B-lymphocyte antigen CD19 Human genes 0.000 claims 2
- 101710094296 CD160 antigen Proteins 0.000 claims 2
- 208000032170 Congenital Abnormalities Diseases 0.000 claims 2
- 206010010356 Congenital anomaly Diseases 0.000 claims 2
- 101001022185 Homo sapiens Alpha-(1,3)-fucosyltransferase 4 Proteins 0.000 claims 2
- 101000980825 Homo sapiens B-lymphocyte antigen CD19 Proteins 0.000 claims 2
- 101000946889 Homo sapiens Monocyte differentiation antigen CD14 Proteins 0.000 claims 2
- 101000581981 Homo sapiens Neural cell adhesion molecule 1 Proteins 0.000 claims 2
- 102100038007 Low affinity immunoglobulin epsilon Fc receptor Human genes 0.000 claims 2
- 208000036626 Mental retardation Diseases 0.000 claims 2
- 102100035877 Monocyte differentiation antigen CD14 Human genes 0.000 claims 2
- 206010028980 Neoplasm Diseases 0.000 claims 2
- 208000012902 Nervous system disease Diseases 0.000 claims 2
- 102100027347 Neural cell adhesion molecule 1 Human genes 0.000 claims 2
- 208000025966 Neurological disease Diseases 0.000 claims 2
- 208000008589 Obesity Diseases 0.000 claims 2
- 102100021494 Protein S100-P Human genes 0.000 claims 2
- 102100034906 Transmembrane 4 L6 family member 19 Human genes 0.000 claims 2
- 210000003719 b-lymphocyte Anatomy 0.000 claims 2
- 230000007698 birth defect Effects 0.000 claims 2
- 210000000601 blood cell Anatomy 0.000 claims 2
- 210000002449 bone cell Anatomy 0.000 claims 2
- 201000011510 cancer Diseases 0.000 claims 2
- 238000002487 chromatin immunoprecipitation Methods 0.000 claims 2
- OPTASPLRGRRNAP-UHFFFAOYSA-N cytosine Chemical compound NC=1C=CNC(=O)N=1 OPTASPLRGRRNAP-UHFFFAOYSA-N 0.000 claims 2
- 210000001151 cytotoxic T lymphocyte Anatomy 0.000 claims 2
- 230000000694 effects Effects 0.000 claims 2
- 210000001671 embryonic stem cell Anatomy 0.000 claims 2
- 210000003714 granulocyte Anatomy 0.000 claims 2
- 208000014829 head and neck neoplasm Diseases 0.000 claims 2
- 210000002443 helper t lymphocyte Anatomy 0.000 claims 2
- 210000002865 immune cell Anatomy 0.000 claims 2
- 208000026278 immune system disease Diseases 0.000 claims 2
- 210000003292 kidney cell Anatomy 0.000 claims 2
- 239000000463 material Substances 0.000 claims 2
- 238000012544 monitoring process Methods 0.000 claims 2
- 210000001616 monocyte Anatomy 0.000 claims 2
- 210000000822 natural killer cell Anatomy 0.000 claims 2
- 210000002569 neuron Anatomy 0.000 claims 2
- 235000020824 obesity Nutrition 0.000 claims 2
- 208000003200 Adenoma Diseases 0.000 claims 1
- 206010001233 Adenoma benign Diseases 0.000 claims 1
- 206010005003 Bladder cancer Diseases 0.000 claims 1
- 206010006187 Breast cancer Diseases 0.000 claims 1
- 208000026310 Breast neoplasm Diseases 0.000 claims 1
- 102000017420 CD3 protein, epsilon/gamma/delta subunit Human genes 0.000 claims 1
- 108050005493 CD3 protein, epsilon/gamma/delta subunit Proteins 0.000 claims 1
- 206010008342 Cervix carcinoma Diseases 0.000 claims 1
- 206010009944 Colon cancer Diseases 0.000 claims 1
- 208000001333 Colorectal Neoplasms Diseases 0.000 claims 1
- 238000009007 Diagnostic Kit Methods 0.000 claims 1
- 208000001976 Endocrine Gland Neoplasms Diseases 0.000 claims 1
- 208000000461 Esophageal Neoplasms Diseases 0.000 claims 1
- 108700039887 Essential Genes Proteins 0.000 claims 1
- 102100027581 Forkhead box protein P3 Human genes 0.000 claims 1
- 206010017993 Gastrointestinal neoplasms Diseases 0.000 claims 1
- 102100031181 Glyceraldehyde-3-phosphate dehydrogenase Human genes 0.000 claims 1
- 102100021186 Granulysin Human genes 0.000 claims 1
- 102300051372 Homeodomain-interacting protein kinase 3 isoform 1 Human genes 0.000 claims 1
- 101000761938 Homo sapiens CD160 antigen Proteins 0.000 claims 1
- 101000861452 Homo sapiens Forkhead box protein P3 Proteins 0.000 claims 1
- 101001040751 Homo sapiens Granulysin Proteins 0.000 claims 1
- 101600085189 Homo sapiens Homeodomain-interacting protein kinase 3 (isoform 1) Proteins 0.000 claims 1
- 101001022948 Homo sapiens LIM domain-binding protein 2 Proteins 0.000 claims 1
- 101000878605 Homo sapiens Low affinity immunoglobulin epsilon Fc receptor Proteins 0.000 claims 1
- 101000821881 Homo sapiens Protein S100-P Proteins 0.000 claims 1
- 101000658571 Homo sapiens Transmembrane 4 L6 family member 19 Proteins 0.000 claims 1
- 102100035113 LIM domain-binding protein 2 Human genes 0.000 claims 1
- 101710109756 Low affinity immunoglobulin epsilon Fc receptor Proteins 0.000 claims 1
- 206010058467 Lung neoplasm malignant Diseases 0.000 claims 1
- 206010025323 Lymphomas Diseases 0.000 claims 1
- 206010030155 Oesophageal carcinoma Diseases 0.000 claims 1
- 206010033128 Ovarian cancer Diseases 0.000 claims 1
- 206010061535 Ovarian neoplasm Diseases 0.000 claims 1
- 206010061902 Pancreatic neoplasm Diseases 0.000 claims 1
- 102000023159 Platelet Glycoprotein GPIb-IX Complex Human genes 0.000 claims 1
- 108010045766 Platelet Glycoprotein GPIb-IX Complex Proteins 0.000 claims 1
- 206010060862 Prostate cancer Diseases 0.000 claims 1
- 208000000236 Prostatic Neoplasms Diseases 0.000 claims 1
- 101710122257 Protein S100-P Proteins 0.000 claims 1
- 208000000453 Skin Neoplasms Diseases 0.000 claims 1
- 208000005718 Stomach Neoplasms Diseases 0.000 claims 1
- 101710087263 Transmembrane 4 L6 family member 19 Proteins 0.000 claims 1
- 208000007097 Urinary Bladder Neoplasms Diseases 0.000 claims 1
- 208000006105 Uterine Cervical Neoplasms Diseases 0.000 claims 1
- 208000002495 Uterine Neoplasms Diseases 0.000 claims 1
- 238000004458 analytical method Methods 0.000 claims 1
- 238000003556 assay Methods 0.000 claims 1
- 102000023732 binding proteins Human genes 0.000 claims 1
- 108091008324 binding proteins Proteins 0.000 claims 1
- 239000012472 biological sample Substances 0.000 claims 1
- 210000004369 blood Anatomy 0.000 claims 1
- 239000008280 blood Substances 0.000 claims 1
- 201000010881 cervical cancer Diseases 0.000 claims 1
- 210000001072 colon Anatomy 0.000 claims 1
- 229940104302 cytosine Drugs 0.000 claims 1
- 238000003745 diagnosis Methods 0.000 claims 1
- 230000029087 digestion Effects 0.000 claims 1
- 201000004101 esophageal cancer Diseases 0.000 claims 1
- 230000002550 fecal effect Effects 0.000 claims 1
- 206010017758 gastric cancer Diseases 0.000 claims 1
- 208000004104 gestational diabetes Diseases 0.000 claims 1
- 108020004445 glyceraldehyde-3-phosphate dehydrogenase Proteins 0.000 claims 1
- 208000032839 leukemia Diseases 0.000 claims 1
- 210000004072 lung Anatomy 0.000 claims 1
- 201000005202 lung cancer Diseases 0.000 claims 1
- 208000020816 lung neoplasm Diseases 0.000 claims 1
- 208000029559 malignant endocrine neoplasm Diseases 0.000 claims 1
- 208000015486 malignant pancreatic neoplasm Diseases 0.000 claims 1
- 208000026037 malignant tumor of neck Diseases 0.000 claims 1
- 238000002493 microarray Methods 0.000 claims 1
- 201000002528 pancreatic cancer Diseases 0.000 claims 1
- 208000008443 pancreatic carcinoma Diseases 0.000 claims 1
- 239000013612 plasmid Substances 0.000 claims 1
- 238000001556 precipitation Methods 0.000 claims 1
- 230000035935 pregnancy Effects 0.000 claims 1
- 108090000623 proteins and genes Proteins 0.000 claims 1
- 238000011002 quantification Methods 0.000 claims 1
- 238000003753 real-time PCR Methods 0.000 claims 1
- 210000003296 saliva Anatomy 0.000 claims 1
- 210000000582 semen Anatomy 0.000 claims 1
- 201000000849 skin cancer Diseases 0.000 claims 1
- 201000011549 stomach cancer Diseases 0.000 claims 1
- 210000004243 sweat Anatomy 0.000 claims 1
- 210000001138 tear Anatomy 0.000 claims 1
- 230000001225 therapeutic effect Effects 0.000 claims 1
- 201000005112 urinary bladder cancer Diseases 0.000 claims 1
- 210000002700 urine Anatomy 0.000 claims 1
- 206010046766 uterine cancer Diseases 0.000 claims 1
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| EP10001121.2 | 2010-02-03 | ||
| EP10001121A EP2354242A1 (en) | 2010-02-03 | 2010-02-03 | Assay for determining the type and/or status of a cell based on the epigenetic pattern and the chromatin structure |
| PCT/EP2011/051601 WO2011095564A1 (en) | 2010-02-03 | 2011-02-03 | Assay for determining the type and/or status of a cell based on the epigenetic pattern and the chromatin structure |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2013518574A JP2013518574A (ja) | 2013-05-23 |
| JP2013518574A5 true JP2013518574A5 (https=) | 2014-03-06 |
| JP5992338B2 JP5992338B2 (ja) | 2016-09-14 |
Family
ID=42154213
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2012551627A Expired - Fee Related JP5992338B2 (ja) | 2010-02-03 | 2011-02-03 | エピジェネティックパターン及びクロマチン構造に基づいて細胞の型及び／又は状況を決定するアッセイ |
Country Status (4)
| Country | Link |
|---|---|
| US (3) | US9840736B2 (https=) |
| EP (1) | EP2354242A1 (https=) |
| JP (1) | JP5992338B2 (https=) |
| WO (1) | WO2011095564A1 (https=) |
Families Citing this family (58)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US20170233807A1 (en) | 2008-12-16 | 2017-08-17 | Epiontis Gmbh | Epigenetic Markers for the Identification of Blood Sub-cells of Type 1 |
| US20190300945A1 (en) | 2010-04-05 | 2019-10-03 | Prognosys Biosciences, Inc. | Spatially Encoded Biological Assays |
| WO2011127099A1 (en) | 2010-04-05 | 2011-10-13 | Prognosys Biosciences, Inc. | Spatially encoded biological assays |
| US10787701B2 (en) | 2010-04-05 | 2020-09-29 | Prognosys Biosciences, Inc. | Spatially encoded biological assays |
| GB201106254D0 (en) | 2011-04-13 | 2011-05-25 | Frisen Jonas | Method and product |
| EP4592400A3 (en) | 2012-10-17 | 2025-10-29 | 10x Genomics Sweden AB | Methods and product for optimising localised or spatial detection of gene expression in a tissue sample |
| US10208346B2 (en) | 2013-04-19 | 2019-02-19 | Epiontis Gmbh | Method for identifying the quantitative cellular composition in a biological sample |
| CA2916662C (en) | 2013-06-25 | 2022-03-08 | Prognosys Biosciences, Inc. | Methods and systems for determining spatial patterns of biological targets in a sample |
| DE202015000425U1 (de) * | 2015-01-23 | 2016-04-26 | Deutsches Zentrum für Luft- und Raumfahrt e.V. | Parabolrinnenkollektormodul, Parabolrinnenkollektormoduleinheit sowie solarthermisches Kraftwerk |
| EP3901282B1 (en) | 2015-04-10 | 2023-06-28 | Spatial Transcriptomics AB | Spatially distinguished, multiplex nucleic acid analysis of biological specimens |
| KR101781200B1 (ko) * | 2015-06-26 | 2017-09-22 | 차의과학대학교 산학협력단 | 비만 진단용 마커 tm4sf19 및 이를 이용한 방법 |
| US11519033B2 (en) | 2018-08-28 | 2022-12-06 | 10X Genomics, Inc. | Method for transposase-mediated spatial tagging and analyzing genomic DNA in a biological sample |
| US20210332424A1 (en) * | 2018-08-28 | 2021-10-28 | 10X Genomics, Inc. | Methods of generating an array |
| WO2020123316A2 (en) | 2018-12-10 | 2020-06-18 | 10X Genomics, Inc. | Methods for determining a location of a biological analyte in a biological sample |
| US12529094B2 (en) | 2018-12-10 | 2026-01-20 | 10X Genomics, Inc. | Imaging system hardware |
| US11926867B2 (en) | 2019-01-06 | 2024-03-12 | 10X Genomics, Inc. | Generating capture probes for spatial analysis |
| US11649485B2 (en) | 2019-01-06 | 2023-05-16 | 10X Genomics, Inc. | Generating capture probes for spatial analysis |
| WO2020243579A1 (en) | 2019-05-30 | 2020-12-03 | 10X Genomics, Inc. | Methods of detecting spatial heterogeneity of a biological sample |
| WO2021092433A2 (en) | 2019-11-08 | 2021-05-14 | 10X Genomics, Inc. | Enhancing specificity of analyte binding |
| ES2982420T3 (es) | 2019-12-23 | 2024-10-16 | 10X Genomics Inc | Métodos para el análisis espacial mediante el uso de la ligazón con plantilla de ARN |
| CN115135984B (zh) | 2019-12-23 | 2025-12-23 | 10X基因组学有限公司 | 可逆固定试剂及其使用方法 |
| EP4081656A1 (en) | 2019-12-23 | 2022-11-02 | 10X Genomics, Inc. | Compositions and methods for using fixed biological samples in partition-based assays |
| US12365942B2 (en) | 2020-01-13 | 2025-07-22 | 10X Genomics, Inc. | Methods of decreasing background on a spatial array |
| US12405264B2 (en) | 2020-01-17 | 2025-09-02 | 10X Genomics, Inc. | Electrophoretic system and method for analyte capture |
| US11732299B2 (en) | 2020-01-21 | 2023-08-22 | 10X Genomics, Inc. | Spatial assays with perturbed cells |
| US11702693B2 (en) | 2020-01-21 | 2023-07-18 | 10X Genomics, Inc. | Methods for printing cells and generating arrays of barcoded cells |
| US20210230681A1 (en) | 2020-01-24 | 2021-07-29 | 10X Genomics, Inc. | Methods for spatial analysis using proximity ligation |
| US12076701B2 (en) | 2020-01-31 | 2024-09-03 | 10X Genomics, Inc. | Capturing oligonucleotides in spatial transcriptomics |
| US12110541B2 (en) | 2020-02-03 | 2024-10-08 | 10X Genomics, Inc. | Methods for preparing high-resolution spatial arrays |
| US11898205B2 (en) | 2020-02-03 | 2024-02-13 | 10X Genomics, Inc. | Increasing capture efficiency of spatial assays |
| US11732300B2 (en) | 2020-02-05 | 2023-08-22 | 10X Genomics, Inc. | Increasing efficiency of spatial analysis in a biological sample |
| WO2021158925A1 (en) | 2020-02-07 | 2021-08-12 | 10X Genomics, Inc. | Quantitative and automated permeabilization performance evaluation for spatial transcriptomics |
| US12281357B1 (en) | 2020-02-14 | 2025-04-22 | 10X Genomics, Inc. | In situ spatial barcoding |
| US11891654B2 (en) | 2020-02-24 | 2024-02-06 | 10X Genomics, Inc. | Methods of making gene expression libraries |
| EP4139485B1 (en) | 2020-04-22 | 2023-09-06 | 10X Genomics, Inc. | Methods for spatial analysis using targeted rna depletion |
| EP4153776B1 (en) | 2020-05-22 | 2025-03-05 | 10X Genomics, Inc. | Spatial analysis to detect sequence variants |
| EP4414459B1 (en) | 2020-05-22 | 2025-09-03 | 10X Genomics, Inc. | Simultaneous spatio-temporal measurement of gene expression and cellular activity |
| WO2021242834A1 (en) | 2020-05-26 | 2021-12-02 | 10X Genomics, Inc. | Method for resetting an array |
| US12031177B1 (en) | 2020-06-04 | 2024-07-09 | 10X Genomics, Inc. | Methods of enhancing spatial resolution of transcripts |
| EP4421186B1 (en) | 2020-06-08 | 2025-08-13 | 10X Genomics, Inc. | Methods of determining a surgical margin and methods of use thereof |
| EP4165207B1 (en) | 2020-06-10 | 2024-09-25 | 10X Genomics, Inc. | Methods for determining a location of an analyte in a biological sample |
| ES2994976T3 (en) | 2020-06-25 | 2025-02-05 | 10X Genomics Inc | Spatial analysis of dna methylation |
| US12209280B1 (en) | 2020-07-06 | 2025-01-28 | 10X Genomics, Inc. | Methods of identifying abundance and location of an analyte in a biological sample using second strand synthesis |
| US11761038B1 (en) | 2020-07-06 | 2023-09-19 | 10X Genomics, Inc. | Methods for identifying a location of an RNA in a biological sample |
| US11981960B1 (en) | 2020-07-06 | 2024-05-14 | 10X Genomics, Inc. | Spatial analysis utilizing degradable hydrogels |
| US11981958B1 (en) | 2020-08-20 | 2024-05-14 | 10X Genomics, Inc. | Methods for spatial analysis using DNA capture |
| US20220076780A1 (en) * | 2020-09-04 | 2022-03-10 | 10X Genomics, Inc. | Systems and methods for identifying cell-associated barcodes in mutli-genomic feature data from single-cell partitions |
| US11926822B1 (en) | 2020-09-23 | 2024-03-12 | 10X Genomics, Inc. | Three-dimensional spatial analysis |
| US11827935B1 (en) | 2020-11-19 | 2023-11-28 | 10X Genomics, Inc. | Methods for spatial analysis using rolling circle amplification and detection probes |
| CN112415198B (zh) * | 2020-11-20 | 2022-11-11 | 四川大学华西医院 | Gp1bb检测试剂在制备肺癌筛查试剂盒中的用途 |
| EP4729631A2 (en) | 2020-12-21 | 2026-04-22 | 10X Genomics, Inc. | Methods, compositions, and systems for capturing probes and/or barcodes |
| EP4305196B1 (en) | 2021-04-14 | 2025-04-02 | 10X Genomics, Inc. | Methods of measuring mislocalization of an analyte |
| EP4320271B1 (en) | 2021-05-06 | 2025-03-19 | 10X Genomics, Inc. | Methods for increasing resolution of spatial analysis |
| WO2022256503A1 (en) | 2021-06-03 | 2022-12-08 | 10X Genomics, Inc. | Methods, compositions, kits, and systems for enhancing analyte capture for spatial analysis |
| WO2023034489A1 (en) | 2021-09-01 | 2023-03-09 | 10X Genomics, Inc. | Methods, compositions, and kits for blocking a capture probe on a spatial array |
| WO2023086880A1 (en) | 2021-11-10 | 2023-05-19 | 10X Genomics, Inc. | Methods, compositions, and kits for determining the location of an analyte in a biological sample |
| WO2023102118A2 (en) | 2021-12-01 | 2023-06-08 | 10X Genomics, Inc. | Methods, compositions, and systems for improved in situ detection of analytes and spatial analysis |
| EP4482979B1 (en) | 2022-11-09 | 2025-10-01 | 10X Genomics, Inc. | Methods, compositions, and kits for determining the location of multiple analytes in a biological sample |
Family Cites Families (14)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5422251A (en) | 1986-11-26 | 1995-06-06 | Princeton University | Triple-stranded nucleic acids |
| US5849482A (en) | 1988-09-28 | 1998-12-15 | Epoch Pharmaceuticals, Inc. | Crosslinking oligonucleotides |
| US5176996A (en) | 1988-12-20 | 1993-01-05 | Baylor College Of Medicine | Method for making synthetic oligonucleotides which bind specifically to target sites on duplex DNA molecules, by forming a colinear triplex, the synthetic oligonucleotides and methods of use |
| US6090947A (en) | 1996-02-26 | 2000-07-18 | California Institute Of Technology | Method for the synthesis of pyrrole and imidazole carboxamides on a solid support |
| US5998140A (en) | 1996-07-31 | 1999-12-07 | The Scripps Research Institute | Complex formation between dsDNA and oligomer of cyclic heterocycles |
| AU2001257421A1 (en) * | 2000-04-28 | 2001-11-12 | Sangamo Biosciences, Inc. | Pharmacogenomics and identification of drug targets by reconstruction of signal transduction pathways based on sequences of accessible regions |
| CA2587817A1 (en) | 2004-11-11 | 2006-05-18 | Garvan Institute Of Medical Research | Method of diagnosing cancer and reagents therefor |
| US8298762B2 (en) * | 2005-03-11 | 2012-10-30 | Epiontis Gmbh | Specific DNAS for Epigenetic Characterisation of cells and tissues |
| EP1748080A3 (en) * | 2005-03-11 | 2007-04-11 | Epiontis GmbH | Specific DNAs for epigenetic characterisation of cells and tissues |
| US20070196843A1 (en) | 2005-12-13 | 2007-08-23 | Green Roland D | Method for identification and monitoring of epigenetic modifications |
| GB0700374D0 (en) * | 2007-01-09 | 2007-02-14 | Oncomethylome Sciences S A | NDRG family methylation markers |
| EP2141245A1 (en) * | 2008-07-03 | 2010-01-06 | Ivana Türbachova | DNA methylation analysis of regulatory T cells through DNA-methylation analysis of the TSDR region of the gene foxP3 |
| WO2010074924A1 (en) * | 2008-12-23 | 2010-07-01 | University Of Utah Research Foundation | Identification and regulation of a novel dna demethylase system |
| EP2248913B1 (en) | 2009-04-28 | 2016-10-05 | Epiontis GmbH | GNLY as epigenetic marker for the identification of CD56-expressing natural killer cells |
-
2010
- 2010-02-03 EP EP10001121A patent/EP2354242A1/en not_active Ceased
-
2011
- 2011-02-03 WO PCT/EP2011/051601 patent/WO2011095564A1/en not_active Ceased
- 2011-02-03 JP JP2012551627A patent/JP5992338B2/ja not_active Expired - Fee Related
- 2011-02-03 US US13/575,819 patent/US9840736B2/en active Active
-
2017
- 2017-07-27 US US15/661,585 patent/US20170327889A1/en not_active Abandoned
-
2022
- 2022-01-26 US US17/584,812 patent/US20220145390A1/en active Pending
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