JP2013516482A5 - - Google Patents

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Publication number
JP2013516482A5
JP2013516482A5 JP2012548137A JP2012548137A JP2013516482A5 JP 2013516482 A5 JP2013516482 A5 JP 2013516482A5 JP 2012548137 A JP2012548137 A JP 2012548137A JP 2012548137 A JP2012548137 A JP 2012548137A JP 2013516482 A5 JP2013516482 A5 JP 2013516482A5
Authority
JP
Japan
Prior art keywords
composition
dexmedetomidine
pharmaceutically acceptable
pharmaceutical composition
skin
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
JP2012548137A
Other languages
English (en)
Japanese (ja)
Other versions
JP2013516482A (ja
Filing date
Publication date
Application filed filed Critical
Priority claimed from PCT/US2011/020462 external-priority patent/WO2011085162A2/en
Publication of JP2013516482A publication Critical patent/JP2013516482A/ja
Publication of JP2013516482A5 publication Critical patent/JP2013516482A5/ja
Pending legal-status Critical Current

Links

JP2012548137A 2010-01-08 2011-01-07 局所経皮用デクスメデトミジン組成物およびそれらの使用方法 Pending JP2013516482A (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US29344010P 2010-01-08 2010-01-08
US61/293,440 2010-01-08
PCT/US2011/020462 WO2011085162A2 (en) 2010-01-08 2011-01-07 Topical transdermal dexmedetomidine compositions and methods of use thereof

Publications (2)

Publication Number Publication Date
JP2013516482A JP2013516482A (ja) 2013-05-13
JP2013516482A5 true JP2013516482A5 (enExample) 2014-02-27

Family

ID=44306157

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2012548137A Pending JP2013516482A (ja) 2010-01-08 2011-01-07 局所経皮用デクスメデトミジン組成物およびそれらの使用方法

Country Status (10)

Country Link
US (1) US20130072532A1 (enExample)
EP (1) EP2521544A4 (enExample)
JP (1) JP2013516482A (enExample)
CN (1) CN102753169A (enExample)
AU (1) AU2011204315A1 (enExample)
CA (1) CA2786598A1 (enExample)
MX (1) MX2012007933A (enExample)
NZ (2) NZ703808A (enExample)
RU (1) RU2012133969A (enExample)
WO (1) WO2011085162A2 (enExample)

Families Citing this family (19)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
SG10201604653TA (en) * 2011-12-11 2016-07-28 Recro Pharma Inc Intranasal dexmedetomidine compositions and methods of use thereof
ES2765264T3 (es) * 2013-05-06 2020-06-08 Allergan Inc Agonistas alfa-adrenérgicos para el tratamiento de traumatismo tisular
RU2646512C2 (ru) * 2013-10-07 2018-03-05 ТЕЙКОКУ ФАРМА ЮЭсЭй, ИНК. Устройства для трансдермальной доставки дексмедетомидина и способы их применения
RU2648817C2 (ru) * 2013-10-07 2018-03-28 ТЕЙКОКУ ФАРМА ЮЭсЭй, ИНК. Способы и композиции для лечения абстинентных синдромов с использованием неседативных трансдермальных композиций на основе дексмедетомидина
CN105764496B (zh) * 2013-10-07 2020-09-25 帝国制药美国公司 用于经皮递送非镇静量的右旋美托咪啶的方法和组合物
CA2924188C (en) * 2013-10-07 2018-12-18 Teikoku Pharma Usa, Inc. Methods and compositions for managing pain comprising dexmedetomidine transdermal compositions
TWI709417B (zh) 2013-10-07 2020-11-11 美商帝國製藥美國股份有限公司 使用右美托咪啶經皮組成物用於治療注意力不足過動症、焦慮及失眠的方法及組成物
MA41689A (fr) * 2014-10-15 2017-08-22 Bioxcel Corp Prévention ou traitement de troubles du sommeil au moyen d'une formulation de dexmédétomidine
CA3038354C (en) * 2016-10-31 2021-08-17 Teikoku Pharma Usa, Inc. Methods of managing pain using dexmedetomidine transdermal delivery devices
PT3562486T (pt) 2016-12-31 2024-06-12 Bioxcel Therapeutics Inc Uso de dexmedetomidina sublingual para o tratamento da agitação
CN107929234B (zh) * 2017-12-25 2021-07-23 温州医科大学附属第一医院 一种应用于烧伤创面修复的外用制剂膏体
IL279713B2 (en) 2018-06-27 2025-01-01 Bioxcel Therapeutics Inc Dexmedetomidine-containing layer compositions and methods for their production
WO2020176807A1 (en) 2019-02-27 2020-09-03 Vanderbilt University Methods of treating trigeminal nerve pain
US20220211672A1 (en) 2019-05-01 2022-07-07 Clexio Biosciences Ltd. Methods of treating pruritus
MX2021012824A (es) 2019-05-01 2022-10-19 Clexio Biosciences Ltd Métodos para tratar el prurito.
JP7739256B2 (ja) 2019-07-19 2025-09-16 バイオエクセル セラピューティクス,インコーポレイテッド 鎮静作用のないデクスメデトミジン治療レジメン
CN113577556A (zh) * 2021-08-01 2021-11-02 武汉左点科技有限公司 一种用于阴道康复治疗的生物反馈电刺激方法及装置
CN117582424A (zh) * 2022-08-17 2024-02-23 宜昌人福药业有限责任公司 右美托咪定经皮组合物、透皮贴剂及其制备方法和应用
US11806334B1 (en) 2023-01-12 2023-11-07 Bioxcel Therapeutics, Inc. Non-sedating dexmedetomidine treatment regimens

Family Cites Families (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5124157A (en) * 1989-08-18 1992-06-23 Cygnus Therapeutic Systems Method and device for administering dexmedetomidine transdermally
US5217718A (en) * 1989-08-18 1993-06-08 Cygnus Therapeutic Systems Method and device for administering dexmedetomidine transdermally
FI894911A0 (fi) * 1989-10-17 1989-10-17 Farmos Oy En terapeutiskt vaerdefull foerening.
GB9111732D0 (en) * 1991-05-31 1991-07-24 Orion Yhtymae Oy The use of certain salts of medetomidine and its optically active enantiomers to regulate the rate of transdermal administration of the drugs
GB9913677D0 (en) * 1999-06-11 1999-08-11 Imperial College Formulation
AUPR184500A0 (en) * 2000-12-01 2001-01-04 Drug Delivery Solutions Pty Ltd Dispensing device
US20030022926A1 (en) * 2001-05-07 2003-01-30 Lavand'homme Patricia Method for treating neuropathic pain and pharmaceutical preparation therefor
IL147921A0 (en) * 2002-01-31 2002-08-14 Abdulrazik Mohammad A method for treating central nervous system disorders by ocular dosing
US20050058696A1 (en) * 2003-09-12 2005-03-17 Allergan, Inc. Methods and compositions for the treatment of pain and other alpha 2 adrenergic-mediated conditions
GB0611241D0 (en) * 2006-06-07 2006-07-19 Daniolabs Ltd The treatment of increased sebum production

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