JP2013508295A - 薬物誘発性手足症候群を治療するための組成物および方法 - Google Patents

薬物誘発性手足症候群を治療するための組成物および方法 Download PDF

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JP2013508295A
JP2013508295A JP2012534390A JP2012534390A JP2013508295A JP 2013508295 A JP2013508295 A JP 2013508295A JP 2012534390 A JP2012534390 A JP 2012534390A JP 2012534390 A JP2012534390 A JP 2012534390A JP 2013508295 A JP2013508295 A JP 2013508295A
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ppe
phosphodiesterase inhibitor
drug toxicity
drug
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JP2013508295A5 (enExample
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ハーウィッツ，ハーバート
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デューク・ユニヴァーシティ
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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
    • A61K31/519—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim ortho- or peri-condensed with heterocyclic rings
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
    • A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P39/00—General protective or antinoxious agents
    • A61P39/02—Antidotes
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

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  • Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Public Health (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • General Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Organic Chemistry (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Epidemiology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Toxicology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Biomedical Technology (AREA)
  • Dermatology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
JP2012534390A 2009-10-16 2010-10-15 薬物誘発性手足症候群を治療するための組成物および方法 Pending JP2013508295A (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US27909109P 2009-10-16 2009-10-16
US61/279,091 2009-10-16
PCT/US2010/052836 WO2011047256A1 (en) 2009-10-16 2010-10-15 Compositions and methods for the treatment of drug-induced hand-foot syndrome

Related Child Applications (1)

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JP2015246156A Division JP6063550B2 (ja) 2009-10-16 2015-12-17 薬物誘発性手足症候群を治療するための組成物および方法

Publications (2)

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JP2013508295A true JP2013508295A (ja) 2013-03-07
JP2013508295A5 JP2013508295A5 (enExample) 2013-12-05

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Family Applications (2)

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JP2012534390A Pending JP2013508295A (ja) 2009-10-16 2010-10-15 薬物誘発性手足症候群を治療するための組成物および方法
JP2015246156A Active JP6063550B2 (ja) 2009-10-16 2015-12-17 薬物誘発性手足症候群を治療するための組成物および方法

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JP2015246156A Active JP6063550B2 (ja) 2009-10-16 2015-12-17 薬物誘発性手足症候群を治療するための組成物および方法

Country Status (6)

Country Link
US (2) US9220713B2 (enExample)
EP (1) EP2488642B1 (enExample)
JP (2) JP2013508295A (enExample)
CN (1) CN102648279B (enExample)
AU (1) AU2010306671B2 (enExample)
WO (1) WO2011047256A1 (enExample)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2020528286A (ja) * 2017-08-18 2020-09-24 ザ プロクター アンド ギャンブル カンパニーＴｈｅ Ｐｒｏｃｔｅｒ ＆ Ｇａｍｂｌｅ Ｃｏｍｐａｎｙ 洗浄方法

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US9220713B2 (en) * 2009-10-16 2015-12-29 Duke University Compositions and methods for the treatment of drug-induced hand-foot syndrome
WO2012125379A1 (en) * 2011-03-14 2012-09-20 Cellworks Research India Private Limited Compositions, process of preparation of said compositions and method of treating inflammatory diseases
AU2014278231B2 (en) * 2013-06-11 2017-05-25 KALA BIO, Inc. Urea derivatives and uses thereof
WO2016144230A1 (en) * 2015-03-06 2016-09-15 Telefonaktiebolaget Lm Ericsson (Publ) Method, network device, computer program and computer program product for mobile service chaining
TW201927292A (zh) 2017-12-13 2019-07-16 大陸商上海小午醫藥科技有限公司 一種用於預防或治療與ｅｇｆｒ被抑制相關疾病的方法
TW201943428A (zh) 2018-04-16 2019-11-16 大陸商上海岸闊醫藥科技有限公司 預防或治療腫瘤療法副作用的方法

Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US2002A (en) * 1841-03-12 Tor and planter for plowing
US9004A (en) * 1852-06-08 Improvement in seed-planters
US9019A (en) * 1852-06-15 Charles fleischbl

Family Cites Families (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20020028237A1 (en) * 2000-04-20 2002-03-07 Colbern Gail T. Method for reducing toxicity of a cytotoxic agent
US6683080B2 (en) * 2001-02-02 2004-01-27 Pfizer Inc. Treatment of diabetes mellitus
US20090048179A1 (en) 2005-02-22 2009-02-19 Cedars-Sinai Medical Center Use of 5-phosphodiesterase inhibitors to enhance the permeability of the blood-brain barrier of abnormal brain tissue and the blood-tumor barrier
EP1850852A4 (en) 2005-02-22 2009-11-18 Cedars Sinai Medical Center USE OF SILDENAFIL, VARDENAFIL AND OTHER 5-PHOSPHODIESTERASE INHIBITORS TO INCREASE THE PERMEABILITY OF THE ABNORMAL BLOOD-BRAIN DISEASE
US8067433B2 (en) * 2005-11-09 2011-11-29 Zalicus Inc. Methods, compositions, and kits for the treatment of ophthalmic disorders
US20090197922A1 (en) 2006-01-24 2009-08-06 The University Of Chicago Compositions and methods for treating pulmonary hypertension
AU2007267069B2 (en) 2006-06-01 2011-08-11 Nobera Pharma, S.L. Use of allopurinol for the treatment of palmar plantar erythrodysesthesia
EP2246057A1 (en) 2009-04-29 2010-11-03 Nobera Pharma, S.L. Use of allopurinol for the treatment of hand foot skin reaction
US9220713B2 (en) * 2009-10-16 2015-12-29 Duke University Compositions and methods for the treatment of drug-induced hand-foot syndrome

Patent Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US2002A (en) * 1841-03-12 Tor and planter for plowing
US9004A (en) * 1852-06-08 Improvement in seed-planters
US9019A (en) * 1852-06-15 Charles fleischbl

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2020528286A (ja) * 2017-08-18 2020-09-24 ザ プロクター アンド ギャンブル カンパニーＴｈｅ Ｐｒｏｃｔｅｒ ＆ Ｇａｍｂｌｅ Ｃｏｍｐａｎｙ 洗浄方法

Also Published As

Publication number Publication date
AU2010306671B2 (en) 2015-12-17
CN102648279A (zh) 2012-08-22
EP2488642A1 (en) 2012-08-22
US20160074405A1 (en) 2016-03-17
WO2011047256A1 (en) 2011-04-21
JP6063550B2 (ja) 2017-01-18
CN102648279B (zh) 2015-11-25
US20120258970A1 (en) 2012-10-11
US9220713B2 (en) 2015-12-29
AU2010306671A1 (en) 2012-05-10
EP2488642B1 (en) 2015-03-11
EP2488642A4 (en) 2013-03-06
US9629845B2 (en) 2017-04-25
JP2016094450A (ja) 2016-05-26

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