JP2013505253A - 三環式化合物およびその薬学的使用 - Google Patents
三環式化合物およびその薬学的使用 Download PDFInfo
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| EP2943485B1 (en) | 2013-01-14 | 2017-09-20 | Incyte Holdings Corporation | Bicyclic aromatic carboxamide compounds useful as pim kinase inhibitors |
| TWI662030B (zh) | 2013-01-15 | 2019-06-11 | 英塞特控股公司 | 適用作ｐｉｍ激酶抑制劑之噻唑甲醯胺及吡啶甲醯胺化合物 |
| US9556197B2 (en) | 2013-08-23 | 2017-01-31 | Incyte Corporation | Furo- and thieno-pyridine carboxamide compounds useful as pim kinase inhibitors |
| US9580418B2 (en) | 2014-07-14 | 2017-02-28 | Incyte Corporation | Bicyclic aromatic carboxamide compounds useful as Pim kinase inhibitors |
| WO2016010897A1 (en) | 2014-07-14 | 2016-01-21 | Incyte Corporation | Bicyclic heteroaromatic carboxamide compounds useful as pim kinase inhibitors |
| US9388181B2 (en) | 2014-10-07 | 2016-07-12 | Allergan, Inc. | Substituted 1,2,3,4-tetrahydropyrido[3,4-E] pyrrolo[1,2-A]pyrimidines as kinase |
| WO2016133860A1 (en) * | 2015-02-16 | 2016-08-25 | Board Of Regents Of The University Of Nebraska | Cancer biomarkers and methods of use thereof |
| WO2016196244A1 (en) | 2015-05-29 | 2016-12-08 | Incyte Corporation | Pyridineamine compounds useful as pim kinase inhibitors |
| AR105967A1 (es) | 2015-09-09 | 2017-11-29 | Incyte Corp | Sales de un inhibidor de pim quinasa |
| WO2017059251A1 (en) | 2015-10-02 | 2017-04-06 | Incyte Corporation | Heterocyclic compounds useful as pim kinase inhibitors |
| EP3535243B1 (en) * | 2016-11-04 | 2021-12-15 | Auckland Uniservices Limited | Substituted 9h-xanthen-9-one, 9h-thioxanthen-9-one and acridin-9(10h)-one derivatives and related compounds csf-1r inhibitors for the treatment of cancer |
| KR102464677B1 (ko) * | 2017-08-11 | 2022-11-10 | 셍커 파마슈티컬스 (지앙수) 엘티디. | 단백질 인산화효소 억제제로 작용하는 1h-피라졸로[4,3-h]퀴나졸린 화합물 |
| TW201924683A (zh) | 2017-12-08 | 2019-07-01 | 美商英塞特公司 | 用於治療骨髓增生性贅瘤的低劑量組合療法 |
| US11071727B2 (en) | 2018-01-26 | 2021-07-27 | Northwestern University | Therapeutic targeting of proteolytic cleavage of the mixed lineage leukemia gene product (MLL1) by taspase1 using kinase inhibitors |
| US12116363B2 (en) | 2018-10-19 | 2024-10-15 | Senhwa Biosciences, Inc. | Combinations for immune-modulation in cancer treatment |
| EP4284804A1 (en) | 2021-01-26 | 2023-12-06 | Schrödinger, Inc. | Tricyclic compounds useful in the treatment of cancer, autoimmune and inflammatory disorders |
| US20250282784A1 (en) * | 2022-05-03 | 2025-09-11 | University Of Notre Dame Du Lac | Cytochrome bd oxidase inhibitors and uses thereof |
| US12012414B1 (en) | 2024-01-04 | 2024-06-18 | King Faisal University | Imidazo[1,5-a]pyrido[4,3-e]pyrimidines as CK2 inhibitors |
| US12018026B1 (en) * | 2024-01-10 | 2024-06-25 | King Faisal University | Pyrido[4,3-e][1,2,3]triazolo[1,5-a]pyrimidine as CK2 inhibitors |
| US12071437B1 (en) * | 2024-01-12 | 2024-08-27 | King Faisal University | Pyrazolo[1,5-a]pyrido[4,3-e]pyrimidine-2-carboxylic acids as CK2 inhibitors |
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| CA2507348C (en) * | 2004-05-13 | 2013-07-16 | The Hospital For Sick Children | Real time methylumbelliferone-based assay |
| CN102036561A (zh) * | 2008-02-29 | 2011-04-27 | 赛林药物股份有限公司 | 蛋白激酶调节剂 |
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- 2010-09-16 SG SG2012018438A patent/SG179161A1/en unknown
- 2010-09-16 WO PCT/US2010/049116 patent/WO2011035022A1/en not_active Ceased
- 2010-09-16 JP JP2012529901A patent/JP2013505253A/ja active Pending
- 2010-09-16 EP EP10817825A patent/EP2477495A1/en not_active Withdrawn
- 2010-09-16 CA CA2774148A patent/CA2774148A1/en not_active Abandoned
- 2010-09-16 MX MX2012003316A patent/MX2012003316A/es not_active Application Discontinuation
- 2010-09-16 IN IN3213DEN2012 patent/IN2012DN03213A/en unknown
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- 2010-09-16 US US12/883,703 patent/US20110065712A1/en not_active Abandoned
- 2010-09-16 BR BR112012005957A patent/BR112012005957A2/pt not_active IP Right Cessation
- 2010-09-16 KR KR1020127009466A patent/KR20120103763A/ko not_active Withdrawn
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| EP2477495A1 (en) | 2012-07-25 |
| US20110065712A1 (en) | 2011-03-17 |
| IN2012DN03213A (enExample) | 2015-10-23 |
| MX2012003316A (es) | 2012-07-23 |
| IL218632A0 (en) | 2012-05-31 |
| BR112012005957A2 (pt) | 2019-09-24 |
| CA2774148A1 (en) | 2011-03-24 |
| AU2010295622A1 (en) | 2012-05-10 |
| SG179161A1 (en) | 2012-04-27 |
| CN102647906A (zh) | 2012-08-22 |
| KR20120103763A (ko) | 2012-09-19 |
| WO2011035022A1 (en) | 2011-03-24 |
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