JP2013505205A5 - - Google Patents

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Publication number
JP2013505205A5
JP2013505205A5 JP2012529137A JP2012529137A JP2013505205A5 JP 2013505205 A5 JP2013505205 A5 JP 2013505205A5 JP 2012529137 A JP2012529137 A JP 2012529137A JP 2012529137 A JP2012529137 A JP 2012529137A JP 2013505205 A5 JP2013505205 A5 JP 2013505205A5
Authority
JP
Japan
Prior art keywords
pharmaceutical composition
epratuzumab
administered
composition according
week
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
JP2012529137A
Other languages
English (en)
Japanese (ja)
Other versions
JP2013505205A (ja
JP5816905B2 (ja
Filing date
Publication date
Application filed filed Critical
Priority claimed from PCT/EP2010/005225 external-priority patent/WO2011032633A1/en
Publication of JP2013505205A publication Critical patent/JP2013505205A/ja
Publication of JP2013505205A5 publication Critical patent/JP2013505205A5/ja
Application granted granted Critical
Publication of JP5816905B2 publication Critical patent/JP5816905B2/ja
Expired - Fee Related legal-status Critical Current
Anticipated expiration legal-status Critical

Links

JP2012529137A 2009-09-18 2010-08-26 エプラツズマブを用いる自己免疫疾患及び炎症性疾患の治療 Expired - Fee Related JP5816905B2 (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US24379709P 2009-09-18 2009-09-18
US61/243,797 2009-09-18
PCT/EP2010/005225 WO2011032633A1 (en) 2009-09-18 2010-08-26 Treatment of autoimmune and inflammatory diseases with epratuzumab

Publications (3)

Publication Number Publication Date
JP2013505205A JP2013505205A (ja) 2013-02-14
JP2013505205A5 true JP2013505205A5 (US07981874-20110719-C00313.png) 2013-09-26
JP5816905B2 JP5816905B2 (ja) 2015-11-18

Family

ID=43063209

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2012529137A Expired - Fee Related JP5816905B2 (ja) 2009-09-18 2010-08-26 エプラツズマブを用いる自己免疫疾患及び炎症性疾患の治療

Country Status (13)

Country Link
US (1) US20110070227A1 (US07981874-20110719-C00313.png)
EP (1) EP2478012B1 (US07981874-20110719-C00313.png)
JP (1) JP5816905B2 (US07981874-20110719-C00313.png)
KR (1) KR20120100914A (US07981874-20110719-C00313.png)
CN (1) CN102574920A (US07981874-20110719-C00313.png)
AU (1) AU2010294905B2 (US07981874-20110719-C00313.png)
BR (1) BR112012006035A2 (US07981874-20110719-C00313.png)
CA (1) CA2774244A1 (US07981874-20110719-C00313.png)
EA (1) EA026902B1 (US07981874-20110719-C00313.png)
ES (1) ES2608661T3 (US07981874-20110719-C00313.png)
IN (1) IN2012DN02196A (US07981874-20110719-C00313.png)
MX (1) MX341117B (US07981874-20110719-C00313.png)
WO (1) WO2011032633A1 (US07981874-20110719-C00313.png)

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US20080311078A1 (en) 2005-06-14 2008-12-18 Gokarn Yatin R Self-Buffering Protein Formulations
EP2789684B1 (en) 2008-05-23 2016-12-21 Siwa Corporation Methods and compositions for facilitating regeneration
EP3578205A1 (en) 2010-08-06 2019-12-11 ModernaTX, Inc. A pharmaceutical formulation comprising engineered nucleic acids and medical use thereof
CN104531812A (zh) 2010-10-01 2015-04-22 现代治疗公司 设计核酸及其使用方法
JP2014511687A (ja) 2011-03-31 2014-05-19 モデルナ セラピューティクス インコーポレイテッド 工学操作された核酸の送達および製剤
US9464124B2 (en) 2011-09-12 2016-10-11 Moderna Therapeutics, Inc. Engineered nucleic acids and methods of use thereof
ES2911677T3 (es) 2011-10-03 2022-05-20 Modernatx Inc Nucleósidos, nucleótidos y ácidos nucleicos modificados, y sus usos
US9757458B2 (en) * 2011-12-05 2017-09-12 Immunomedics, Inc. Crosslinking of CD22 by epratuzumab triggers BCR signaling and caspase-dependent apoptosis in hematopoietic cancer cells
RS63244B1 (sr) 2011-12-16 2022-06-30 Modernatx Inc Kompozicije modifikovane mrna
US20140010861A1 (en) 2012-04-02 2014-01-09 modeRNA Therapeutics Modified polynucleotides for the production of proteins associated with human disease
US9878056B2 (en) 2012-04-02 2018-01-30 Modernatx, Inc. Modified polynucleotides for the production of cosmetic proteins and peptides
US9283287B2 (en) 2012-04-02 2016-03-15 Moderna Therapeutics, Inc. Modified polynucleotides for the production of nuclear proteins
US9572897B2 (en) 2012-04-02 2017-02-21 Modernatx, Inc. Modified polynucleotides for the production of cytoplasmic and cytoskeletal proteins
PT2906251T (pt) * 2012-10-12 2017-12-04 Medimmune Ltd Conjugados de pirrolobenzodiazepina-anticorpo anti-cd22
LT2922554T (lt) 2012-11-26 2022-06-27 Modernatx, Inc. Terminaliai modifikuota rnr
US8980864B2 (en) 2013-03-15 2015-03-17 Moderna Therapeutics, Inc. Compositions and methods of altering cholesterol levels
US10023626B2 (en) 2013-09-30 2018-07-17 Modernatx, Inc. Polynucleotides encoding immune modulating polypeptides
KR20160067219A (ko) 2013-10-03 2016-06-13 모더나 세라퓨틱스, 인코포레이티드 저밀도 지단백질 수용체를 암호화하는 폴리뉴클레오타이드
US9956299B2 (en) 2013-10-11 2018-05-01 Medimmune Limited Pyrrolobenzodiazepine—antibody conjugates
EP3954703A3 (en) 2014-05-29 2022-05-18 MacroGenics, Inc. Tri-specific binding molecules and methods of use thereof
IL251210B2 (en) * 2014-09-19 2023-12-01 Siwa Corp Anti-aging antibodies for the treatment of inflammation and autoimmune disorders
US10358502B2 (en) 2014-12-18 2019-07-23 Siwa Corporation Product and method for treating sarcopenia
US9993535B2 (en) 2014-12-18 2018-06-12 Siwa Corporation Method and composition for treating sarcopenia
GB201506402D0 (en) 2015-04-15 2015-05-27 Berkel Patricius H C Van And Howard Philip W Site-specific antibody-drug conjugates
GB201506411D0 (en) 2015-04-15 2015-05-27 Bergenbio As Humanized anti-axl antibodies
WO2018191718A1 (en) 2017-04-13 2018-10-18 Siwa Corporation Humanized monoclonal advanced glycation end-product antibody
CN109071675A (zh) 2016-02-19 2018-12-21 Siwa有限公司 使用高级糖化终产物(age)的抗体治疗癌症、杀死转移性癌细胞和预防癌症转移的方法和组合物
US11958900B2 (en) 2016-04-15 2024-04-16 Siwa Corporation Anti-age antibodies for treating neurodegenerative disorders
WO2017222535A1 (en) 2016-06-23 2017-12-28 Siwa Corporation Vaccines for use in treating various diseases and disorders
GB201617466D0 (en) 2016-10-14 2016-11-30 Medimmune Ltd Pyrrolobenzodiazepine conjugates
MX2019004580A (es) 2016-10-21 2019-08-12 Amgen Inc Formulaciones farmaceuticas y metodos para prepararlas.
GB201702031D0 (en) 2017-02-08 2017-03-22 Medlmmune Ltd Pyrrolobenzodiazepine-antibody conjugates
DK3544636T3 (da) 2017-02-08 2021-05-10 Adc Therapeutics Sa Pyrrolobenzodiazepin-antistof-konjugater
RS63502B1 (sr) 2017-04-18 2022-09-30 Medimmune Ltd Konjugati pirolobenzodiazepina
CA3057748A1 (en) 2017-04-20 2018-10-25 Adc Therapeutics Sa Combination therapy with an anti-axl antibody-drug conjugate
UA127900C2 (uk) 2017-06-14 2024-02-07 Ейдісі Терапьютікс Са Схема дозування для введення adc до cd19
WO2019034764A1 (en) 2017-08-18 2019-02-21 Medimmune Limited CONJUGATES OF PYRROLOBENZODIAZEPINE
US11518801B1 (en) 2017-12-22 2022-12-06 Siwa Corporation Methods and compositions for treating diabetes and diabetic complications
GB201803342D0 (en) 2018-03-01 2018-04-18 Medimmune Ltd Methods
GB201806022D0 (en) 2018-04-12 2018-05-30 Medimmune Ltd Pyrrolobenzodiazepines and conjugates thereof
EP3867280A4 (en) * 2018-10-18 2022-11-09 Sinomab Bioscience Limited METHODS OF TREATMENT OF RHEUMATOID ARTHRITIS

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US5179017A (en) * 1980-02-25 1993-01-12 The Trustees Of Columbia University In The City Of New York Processes for inserting DNA into eucaryotic cells and for producing proteinaceous materials
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US5484892A (en) * 1993-05-21 1996-01-16 Dana-Farber Cancer Institute, Inc. Monoclonal antibodies that block ligand binding to the CD22 receptor in mature B cells
AU3272695A (en) * 1994-08-12 1996-03-07 Immunomedics Inc. Immunoconjugates and humanized antibodies specific for b-cell lymphoma and leukemia cells
DE05075555T1 (de) * 1999-06-09 2007-02-08 Immunomedics, Inc. Immuntherapie von Autoimmunerkrankungen durch die Verwendung von B-Zell-spezifischen Antikörpern
EP2330130B1 (en) * 2002-10-17 2014-08-27 Genmab A/S Human monoclonal antibodies against CD20
WO2007103469A2 (en) * 2006-03-06 2007-09-13 Aeres Biomedical Ltd. Humanized anti-cd22 antibodies and their use in treatment of oncology, transplantation and autoimmune disease
UA95958C2 (en) * 2006-05-30 2011-09-26 Дженентек, Инк. Antibody that binds to cd22, immunoconjugates and uses therefor
US8283162B2 (en) * 2009-03-10 2012-10-09 Abbott Laboratories Antibodies relating to PIVKAII and uses thereof

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