JP2013501224A - 葉酸を標的とした診断及び処置 - Google Patents
葉酸を標的とした診断及び処置 Download PDFInfo
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- JP2013501224A JP2013501224A JP2012523104A JP2012523104A JP2013501224A JP 2013501224 A JP2013501224 A JP 2013501224A JP 2012523104 A JP2012523104 A JP 2012523104A JP 2012523104 A JP2012523104 A JP 2012523104A JP 2013501224 A JP2013501224 A JP 2013501224A
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- A61K51/04—Organic compounds
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- A61K51/044—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine, rifamycins
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- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
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- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/58—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving labelled substances
- G01N33/60—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving labelled substances involving radioactive labelled substances
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- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/94—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving narcotics or drugs or pharmaceuticals, neurotransmitters or associated receptors
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| EP3838298B1 (en) | 2007-08-17 | 2025-02-26 | Purdue Research Foundation | Psma binding ligand-linker conjugates and methods for using |
| US9951324B2 (en) | 2010-02-25 | 2018-04-24 | Purdue Research Foundation | PSMA binding ligand-linker conjugates and methods for using |
| MX2013005196A (es) | 2010-11-12 | 2013-06-28 | Endocyte Inc | Metodos para tratamiento del cancer. |
| CN103607891A (zh) * | 2011-04-12 | 2014-02-26 | 恩多塞特公司 | 固体药用组合物 |
| EA201890915A1 (ru) | 2012-11-15 | 2018-09-28 | Эндосайт, Инк. | Конъюгаты для доставки лекарственных средств и способы лечения заболеваний, вызванных клетками, экспрессирующими psma |
| US20140154702A1 (en) * | 2012-11-30 | 2014-06-05 | Endocyte, Inc. | Methods For Treating Cancer Using Combination Therapies |
| US10188738B2 (en) | 2013-10-16 | 2019-01-29 | Université Libre de Bruxelles | Formulations useful in the treatment of proliferative diseases affecting the respiratory tract |
| HRP20240398T1 (hr) | 2013-10-18 | 2024-06-07 | Novartis Ag | Označeni inhibitori prostata specifičnog membranskog antigena (psma), njihova upotreba kao sredstava za snimanje i farmaceutska sredstva za liječenje raka prostate |
| KR102457827B1 (ko) | 2013-11-14 | 2022-10-24 | 엔도사이트, 인코포레이티드 | 양전자 방출 단층 촬영용 화합물 |
| ES2745799T3 (es) | 2013-11-19 | 2020-03-03 | Purdue Research Foundation | Método de selección de pacientes para inflamación |
| US10188759B2 (en) | 2015-01-07 | 2019-01-29 | Endocyte, Inc. | Conjugates for imaging |
| CN107427009A (zh) * | 2015-01-11 | 2017-12-01 | 恩多塞特公司 | 癌症成像剂 |
| IL237525A (en) | 2015-03-03 | 2017-05-29 | Shalom Eli | Method for labeling a prostate-specific membrane antigen with a radioactive isotope |
| CN110678204A (zh) * | 2016-03-29 | 2020-01-10 | 恩多塞特公司 | 用于靶向肿瘤相关巨噬细胞的叶酸缀合物 |
| US10940112B2 (en) | 2016-05-04 | 2021-03-09 | L.E.A.F. Holdings Group Llc | Targeted liposomal gemcitabine compositions and methods thereof |
| AU2017271550B2 (en) * | 2016-05-25 | 2023-11-02 | Endocyte, Inc. | Method of treating cancer by targeting myeloid-derived suppressor cells |
| CN112368024A (zh) | 2018-04-17 | 2021-02-12 | 恩多塞特公司 | 治疗癌症的方法 |
| CN114096264B (zh) | 2019-05-20 | 2025-03-14 | 因多塞特股份有限公司 | 制备psma缀合物的方法 |
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| JP2006316040A (ja) * | 2005-05-13 | 2006-11-24 | Genentech Inc | Ｈｅｒｃｅｐｔｉｎ（登録商標）補助療法 |
| WO2008051525A2 (en) * | 2006-10-25 | 2008-05-02 | Schering Corporation | Methods of treating ovarian cancer |
| JP2008537778A (ja) * | 2005-03-30 | 2008-09-25 | パーデュー・リサーチ・ファウンデーション | 細胞の葉酸ビタミン受容体の定量化による癌予後診断法 |
| WO2009002993A1 (en) * | 2007-06-25 | 2008-12-31 | Endocyte, Inc. | Conjugates containing hydrophilic spacer linkers |
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| DK1592457T3 (da) * | 2003-01-27 | 2012-10-22 | Endocyte Inc | Folat-vinblastin-konjugat som lægemiddel |
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| EP1863816B1 (en) * | 2005-03-16 | 2014-06-25 | Endocyte, Inc. | Synthesis and purification of pteroic acid and conjugates thereof |
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2010
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| JP2008537778A (ja) * | 2005-03-30 | 2008-09-25 | パーデュー・リサーチ・ファウンデーション | 細胞の葉酸ビタミン受容体の定量化による癌予後診断法 |
| JP2006316040A (ja) * | 2005-05-13 | 2006-11-24 | Genentech Inc | Ｈｅｒｃｅｐｔｉｎ（登録商標）補助療法 |
| WO2008051525A2 (en) * | 2006-10-25 | 2008-05-02 | Schering Corporation | Methods of treating ovarian cancer |
| WO2009002993A1 (en) * | 2007-06-25 | 2008-12-31 | Endocyte, Inc. | Conjugates containing hydrophilic spacer linkers |
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Also Published As
| Publication number | Publication date |
|---|---|
| KR20120050462A (ko) | 2012-05-18 |
| NZ598145A (en) | 2014-10-31 |
| CA2769754A1 (en) | 2011-02-03 |
| AU2010278734A1 (en) | 2012-02-23 |
| US20140140925A1 (en) | 2014-05-22 |
| IN2012DN01708A (enExample) | 2015-06-05 |
| WO2011014821A1 (en) | 2011-02-03 |
| US20120128587A1 (en) | 2012-05-24 |
| EP2460013A1 (en) | 2012-06-06 |
| CN104857534A (zh) | 2015-08-26 |
| EP2460013A4 (en) | 2013-04-03 |
| BR112012002064A2 (pt) | 2017-05-09 |
| IL217744A0 (en) | 2012-03-29 |
| RU2012105641A (ru) | 2013-09-10 |
| CN102549434A (zh) | 2012-07-04 |
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