JP2013090994A - 容器閉鎖配送システム - Google Patents
容器閉鎖配送システム Download PDFInfo
- Publication number
- JP2013090994A JP2013090994A JP2013031955A JP2013031955A JP2013090994A JP 2013090994 A JP2013090994 A JP 2013090994A JP 2013031955 A JP2013031955 A JP 2013031955A JP 2013031955 A JP2013031955 A JP 2013031955A JP 2013090994 A JP2013090994 A JP 2013090994A
- Authority
- JP
- Japan
- Prior art keywords
- component
- container
- powder
- plunger assembly
- injection port
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
Images
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
- A61M5/178—Syringes
- A61M5/31—Details
- A61M5/315—Pistons; Piston-rods; Guiding, blocking or restricting the movement of the rod or piston; Appliances on the rod for facilitating dosing ; Dosing mechanisms
- A61M5/31596—Pistons; Piston-rods; Guiding, blocking or restricting the movement of the rod or piston; Appliances on the rod for facilitating dosing ; Dosing mechanisms comprising means for injection of two or more media, e.g. by mixing
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61J—CONTAINERS SPECIALLY ADAPTED FOR MEDICAL OR PHARMACEUTICAL PURPOSES; DEVICES OR METHODS SPECIALLY ADAPTED FOR BRINGING PHARMACEUTICAL PRODUCTS INTO PARTICULAR PHYSICAL OR ADMINISTERING FORMS; DEVICES FOR ADMINISTERING FOOD OR MEDICINES ORALLY; BABY COMFORTERS; DEVICES FOR RECEIVING SPITTLE
- A61J3/00—Devices or methods specially adapted for bringing pharmaceutical products into particular physical or administering forms
- A61J3/02—Devices or methods specially adapted for bringing pharmaceutical products into particular physical or administering forms into the form of powders
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
- A61M5/178—Syringes
- A61M5/31—Details
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61J—CONTAINERS SPECIALLY ADAPTED FOR MEDICAL OR PHARMACEUTICAL PURPOSES; DEVICES OR METHODS SPECIALLY ADAPTED FOR BRINGING PHARMACEUTICAL PRODUCTS INTO PARTICULAR PHYSICAL OR ADMINISTERING FORMS; DEVICES FOR ADMINISTERING FOOD OR MEDICINES ORALLY; BABY COMFORTERS; DEVICES FOR RECEIVING SPITTLE
- A61J1/00—Containers specially adapted for medical or pharmaceutical purposes
- A61J1/14—Details; Accessories therefor
- A61J1/20—Arrangements for transferring or mixing fluids, e.g. from vial to syringe
- A61J1/2096—Combination of a vial and a syringe for transferring or mixing their contents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
- A61M5/14—Infusion devices, e.g. infusing by gravity; Blood infusion; Accessories therefor
- A61M5/142—Pressure infusion, e.g. using pumps
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
- A61M5/178—Syringes
- A61M5/31—Details
- A61M5/32—Needles; Details of needles pertaining to their connection with syringe or hub; Accessories for bringing the needle into, or holding the needle on, the body; Devices for protection of needles
- A61M5/34—Constructions for connecting the needle, e.g. to syringe nozzle or needle hub
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
- A61M5/178—Syringes
- A61M5/31—Details
- A61M2005/3117—Means preventing contamination of the medicament compartment of a syringe
- A61M2005/3118—Means preventing contamination of the medicament compartment of a syringe via the distal end of a syringe, i.e. syringe end for mounting a needle cannula
- A61M2005/312—Means preventing contamination of the medicament compartment of a syringe via the distal end of a syringe, i.e. syringe end for mounting a needle cannula comprising sealing means, e.g. severable caps, to be removed prior to injection by, e.g. tearing or twisting
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
- A61M5/178—Syringes
- A61M5/31—Details
- A61M2005/3128—Incorporating one-way valves, e.g. pressure-relief or non-return valves
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
- A61M5/178—Syringes
- A61M5/31—Details
- A61M5/3129—Syringe barrels
- A61M2005/3132—Syringe barrels having flow passages for injection agents at the distal end of the barrel to bypass a sealing stopper after its displacement to this end due to internal pressure increase
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
- A61M5/178—Syringes
- A61M5/31—Details
- A61M5/315—Pistons; Piston-rods; Guiding, blocking or restricting the movement of the rod or piston; Appliances on the rod for facilitating dosing ; Dosing mechanisms
- A61M5/31596—Pistons; Piston-rods; Guiding, blocking or restricting the movement of the rod or piston; Appliances on the rod for facilitating dosing ; Dosing mechanisms comprising means for injection of two or more media, e.g. by mixing
- A61M2005/31598—Pistons; Piston-rods; Guiding, blocking or restricting the movement of the rod or piston; Appliances on the rod for facilitating dosing ; Dosing mechanisms comprising means for injection of two or more media, e.g. by mixing having multiple telescopically sliding coaxial pistons encompassing volumes for components to be mixed
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
- A61M5/178—Syringes
- A61M5/24—Ampoule syringes, i.e. syringes with needle for use in combination with replaceable ampoules or carpules, e.g. automatic
- A61M5/2448—Ampoule syringes, i.e. syringes with needle for use in combination with replaceable ampoules or carpules, e.g. automatic comprising means for injection of two or more media, e.g. by mixing
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
- A61M5/178—Syringes
- A61M5/31—Details
- A61M5/32—Needles; Details of needles pertaining to their connection with syringe or hub; Accessories for bringing the needle into, or holding the needle on, the body; Devices for protection of needles
- A61M5/3294—Needles; Details of needles pertaining to their connection with syringe or hub; Accessories for bringing the needle into, or holding the needle on, the body; Devices for protection of needles comprising means for injection of two or more media, e.g. by mixing
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
- A61M5/178—Syringes
- A61M5/31—Details
- A61M5/32—Needles; Details of needles pertaining to their connection with syringe or hub; Accessories for bringing the needle into, or holding the needle on, the body; Devices for protection of needles
- A61M5/34—Constructions for connecting the needle, e.g. to syringe nozzle or needle hub
- A61M5/344—Constructions for connecting the needle, e.g. to syringe nozzle or needle hub using additional parts, e.g. clamping rings or collets
- A61M5/345—Adaptors positioned between needle hub and syringe nozzle
Abstract
【解決手段】このシステムは貯蔵安定粉末製剤および容器閉鎖組立体を含み、製剤は標準充填完成設備に充填かつ凍結され、製剤および凍結乾燥法は希釈剤との接触により容易に溶解する粉末を生成するのに最適であり、それにより分離した再構成/混合/プライミング工程を必要とすることなく凍結乾燥物の直接的注入を促進する。
【選択図】図2
Description
600 容器閉鎖組立体
Claims (8)
- 粉末医薬物の投与のための配送装置であって、
一端に注射ポート、希釈剤容器保持室、および前記注射ポートへの希釈剤の流れを促進する作動手段を有する第一構成要素、
最小限のヘッドスペースにより凍結乾燥薬粉末を収容する第二構成要素、を含み、
第二構成要素は一端に注射ポートを有しかつ反対端で第一構成要素と係合でき、
第二構成要素は第一構成要素の作動により第一構成要素から注射された希釈剤を第二構成要素内の粉末に遭遇させ、迅速再構成および第二構成要素の注射ポートへの通過を可能にするプランジャ組立体を含む、配送装置。 - 第二構成要素は、プランジャ組立体および生成物容器構成要素を含む容器閉鎖組立体であり、
前記プランジャ組立体は、
標準タイプのルアスリップ注射器の摩擦嵌めを可能にするルアロックタブ取り付けキャビティ、
典型的ルアロック注射器を収容できる円形キャビティ、および
組立てられた前記プランジャ組立体への流体の流れを促進する所定流体移送チャンネルを含み、かつ
前記生成物容器構成要素は、
凍結乾燥される液体活性成分を保持できかつ前記プランジャ組立体を受けることのできる室を有する開放端、
前記生成物容器の側壁に一体化された係止隆起、
同軸中空注射ポートを含む反対側の下ベース、および
前記下ベースに一体化された螺旋状混合チャンネルを含む、請求項1の装置。 - 第二構成要素は、プラグ構成要素、上カップ構成要素、および生成物容器構成要素を含む容器閉鎖組立体であり、
前記プラグ構成要素は、
プラグ構成要素の外側で基端から先端へ軸方向に延在し前記プラグ構成要素への流体の流れを可能にする流体移送チャンネルを含み、
前記上カップ構成要素は、
標準タイプのルアスリップ注射器の摩擦嵌めを可能にするルアロックタブ取り付けキャビティ、
典型的ルアロック注射器を収容できる円形キャビティ、
前記プラグ構成要素を受けることができてプランジャ組立体を形成する中空円形内側、および
組立てられた前記プランジャ組立体への流体の流れを促進する所定流体移送チャンネルを含み、かつ
前記生成物容器構成要素は、
凍結乾燥される液体活性成分を保持できかつ前記プランジャ組立体を受けることのできる室を有する開放端、
前記生成物容器の側壁に一体化された係止隆起、
同軸中空注射ポートを含む反対側の下ベース、および
前記下ベースに一体化された螺旋状混合チャンネルを含む、請求項1の装置。 - 凍結乾燥医薬物に適した容器閉鎖組立体であって、
プランジャ組立体および生成物容器構成要素を含み、
前記プランジャ組立体は、
標準タイプのルアスリップ注射器の摩擦嵌めを可能にするルアロックタブ取り付けキャビティ、
典型的ルアロック注射器を収容できる円形キャビティ、および
組立てられた前記プランジャ組立体へ流体の流れを促進する所定流体移送チャンネルを含み、かつ
前記生成物容器構成要素は、
凍結乾燥される液体活性成分を保持できかつ前記プランジャ組立体を受けることのできる室を有する開放端、
前記生成物容器の側壁に一体化された係止隆起、
同軸中空注射ポートを含む反対側の下ベース、および
前記下ベースに一体化された螺旋状混合チャンネルを含む、容器閉鎖組立体。 - 凍結乾燥医薬物に適した容器閉鎖組立体であって、
プラグ構成要素、上カップ構成要素、および生成物容器構成要素を含み、
前記プラグ構成要素は、
プラグ構成要素の外側で基端から先端へ軸方向に延在し前記プラグ構成要素への流体の流れを可能にする流体移送チャンネルを含み、
前記上カップ構成要素は、
標準タイプのルアスリップ注射器の摩擦嵌めを可能にするルアロックタブ取り付けキャビティ、
典型的ルアロック注射器を収容できる円形キャビティ、
前記プラグ構成要素を受けることができてプランジャ組立体を形成する中空円形内側、および
組立てられた前記プランジャ組立体への流体の流れを促進する所定流体移送チャンネルを含み、かつ
前記生成物容器構成要素は、
凍結乾燥される液体活性成分を保持できかつ前記プランジャ組立体を受けることのできる室を有する開放端、
前記生成物容器の側壁に一体化された係止隆起、
同軸中空注射ポートを含む反対側の下ベース、および
前記下ベースに一体化された螺旋状混合チャンネルを含む、容器閉鎖組立体。 - 凍結乾燥医薬粉末物を収容する容器閉鎖組立体の改良された製造法であって、
1)業界基準バイアル製造充填ラインへ空の生成物容器を装填し、
2)前記生成物容器に医薬物含有液体製剤を充填し、
3)前記生成物容器の頂面へプランジャ組立体を落下して容器閉鎖組立体を形成し、
4)前記容器閉鎖組立体を凍結乾燥器装置へ設置し、
5)前記容器閉鎖組立体を凍結乾燥プロセスに付し、
6)凍結乾燥器棚の垂直方向の圧縮により前記プランジャ組立体を前記生成物容器へ封止して、最小限ヘッドスペースにより凍結乾燥医薬粉末物を収容する封止された容器閉鎖組立体を形成して凍結乾燥プロセスを終了し、かつ
7)封止された容器閉鎖組立体を結合する、各工程を含む容器閉鎖組立体の製造法 - 凍結乾燥医薬粉末物を投与するための改良された方法であって、
1)第一構成要素および第二構成要素を有する配送装置を用意し、
2)第二構成要素の注射ポートへ標準タイプ針を取り付け、
3)注入部位へ前記針を挿入することにより注入を開始し、
4)第一構成要素を作動させて、希釈剤を第二構成要素内の凍結乾燥粉末に遭遇させ、迅速に再構成し、かつ注入部位へ前記針を挿通する、各工程を含み、
第一構成要素が一端に注射ポート、希釈剤容器保持室、および前記注射ポートへの希釈剤の流れを促進する作動手段を有し、第二構成要素は最小限のヘッドスペースにより凍結乾燥薬粉末を収容しかつ一端で第一構成要素と係合でき、反対端に注射ポートを含み、第二構成要素は第一構成要素の作動により第一構成要素から注射された希釈剤を第二構成要素内の粉末に遭遇させかつ第二構成要素の注射ポートへの通過を可能にするプランジャ組立体を含む、凍結乾燥医薬粉末物投与法。 - 凍結乾燥医薬粉末物の勾配配送を提供する方法であって、
1)第一構成要素および第二構成要素を有する配送装置を用意し、
2)第二構成要素の注射ポートへ標準タイプ針を取り付け、
3)注入部位へ前記針を挿入することにより注入を開始し、
4)第一構成要素を作動させて、希釈剤を第二構成要素内の凍結乾燥粉末に遭遇させ、迅速に再構成し、かつ注入部位へ前記針を挿通する、各工程を含み、
第一構成要素が一端に注射ポート、希釈剤容器保持室、および前記注射ポートへの希釈剤の流れを促進する作動手段を有し、第二構成要素は最小限のヘッドスペースにより凍結乾燥薬粉末を収容しかつ一端で第一構成要素と係合でき、反対端に注射ポートを含み、第二構成要素は第一構成要素の作動により第一構成要素から注射された希釈剤を第二構成要素内の粉末に遭遇させかつ第二構成要素の注射ポートへの通過を可能にするプランジャ組立体を含む、凍結乾燥医薬粉末物の勾配配送法。
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US11/716,223 | 2007-03-09 | ||
US11/716,223 US7959600B2 (en) | 2004-12-30 | 2007-03-09 | Container closure delivery system |
Related Parent Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
JP2009552748A Division JP5255002B2 (ja) | 2007-03-09 | 2008-03-07 | 容器閉鎖配送システム |
Publications (2)
Publication Number | Publication Date |
---|---|
JP2013090994A true JP2013090994A (ja) | 2013-05-16 |
JP5827966B2 JP5827966B2 (ja) | 2015-12-02 |
Family
ID=39760578
Family Applications (2)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
JP2009552748A Expired - Fee Related JP5255002B2 (ja) | 2007-03-09 | 2008-03-07 | 容器閉鎖配送システム |
JP2013031955A Active JP5827966B2 (ja) | 2007-03-09 | 2013-02-21 | 容器閉鎖配送システム |
Family Applications Before (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
JP2009552748A Expired - Fee Related JP5255002B2 (ja) | 2007-03-09 | 2008-03-07 | 容器閉鎖配送システム |
Country Status (10)
Country | Link |
---|---|
US (3) | US7959600B2 (ja) |
EP (2) | EP2743654A3 (ja) |
JP (2) | JP5255002B2 (ja) |
KR (1) | KR101288174B1 (ja) |
AU (1) | AU2008226938B2 (ja) |
CA (1) | CA2679431C (ja) |
ES (1) | ES2500494T3 (ja) |
HK (1) | HK1199300A1 (ja) |
MX (1) | MX2009009474A (ja) |
WO (1) | WO2008112155A1 (ja) |
Cited By (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
TWI817611B (zh) * | 2022-07-15 | 2023-10-01 | 陳昌慈 | 凍乾粉針劑還原器 |
Families Citing this family (25)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US7959600B2 (en) | 2004-12-30 | 2011-06-14 | Byeong S. Chang | Container closure delivery system |
ITMO20060222A1 (it) * | 2006-07-10 | 2008-01-11 | Alfio Bertolini | Pacchetto di medicazione antiemorragico |
US8640358B2 (en) * | 2008-12-22 | 2014-02-04 | Ima Life North America Inc. | Freeze dryer slot door actuator and method |
WO2011019709A2 (en) * | 2009-08-10 | 2011-02-17 | Surmodics, Inc. | Methods, devices, and compositions for intravitreal injection |
US9498271B2 (en) * | 2009-10-29 | 2016-11-22 | Cook Medical Technologies Llc | Coaxial needle cannula with distal spiral mixer and side ports for fluid injection |
ES2667025T3 (es) * | 2009-12-15 | 2018-05-09 | Ascendis Pharma Endocrinology Division A/S | Composición seca de hormona de crecimiento unida transitoriamente a un portador de polímero |
EP2531236A1 (en) * | 2010-02-05 | 2012-12-12 | Sanofi-Aventis Deutschland GmbH | Medicated module with dual safety guards |
JP5973997B2 (ja) | 2010-06-01 | 2016-08-23 | バクスター・インターナショナル・インコーポレイテッドBaxter International Incorp0Rated | 乾燥した安定な止血用組成物を作製するためのプロセス |
EP2663275B1 (en) * | 2011-01-10 | 2017-03-08 | Byeong Seon Chang | Compact medication reconstitution device and method |
US20140295477A1 (en) * | 2011-09-01 | 2014-10-02 | Fresenius Medical Care Holdings, Inc | Kit For Sampling And Detection Of Endotoxin In Aqueous Solution |
WO2014046950A1 (en) | 2012-09-24 | 2014-03-27 | Enable Injections, Llc | Medication vial and injector assemblies and methods of use |
WO2014204894A2 (en) | 2013-06-18 | 2014-12-24 | Enable Injections, Llc | Vial transfer and injection apparatus and method |
WO2015034870A2 (en) * | 2013-09-03 | 2015-03-12 | Arocha Max | Double-chamber mixing syringe and method of use |
US11260177B1 (en) * | 2014-03-18 | 2022-03-01 | Yasser Sadek | Dental anesthetic buffer system |
US10201692B2 (en) | 2014-09-09 | 2019-02-12 | Byeong Seon Chang | Solution delivery device and method |
AU2015374319B2 (en) * | 2014-12-30 | 2019-01-03 | Kindeva Drug Delivery L.P. | Container for mixing and dispensing fluid medication components |
KR102450956B1 (ko) * | 2014-12-30 | 2022-10-04 | 쓰리엠 이노베이티브 프로퍼티즈 컴파니 | 성분들을 혼합 및 분배하기 위한 용기 |
US10143625B2 (en) * | 2015-03-17 | 2018-12-04 | Recon Therapeutics, Inc. | Pharmaceutical reconstitution |
IL265665B1 (en) | 2016-10-07 | 2024-03-01 | Regeneron Pharma | A stable protein at room temperature that has been lyophilized |
US10265471B2 (en) | 2017-08-30 | 2019-04-23 | Pirouette Medical LLC | Compact auto-injector |
US10441714B2 (en) | 2017-10-05 | 2019-10-15 | Pirouette Medical LLC | Protective case for an auto-injector |
WO2021026269A1 (en) * | 2019-08-06 | 2021-02-11 | Microvention, Inc. | Syringe |
US11583473B2 (en) | 2020-09-30 | 2023-02-21 | Nspire Medical Technologies, Llc | Integrated injectable drug packaging and delivery system and methods of use |
US20240050396A1 (en) | 2020-12-21 | 2024-02-15 | Polypid Ltd. | Compositions and methods for the treatment of solid tumors |
WO2024059819A2 (en) | 2022-09-15 | 2024-03-21 | Tff Pharmaceuticals, Inc. | Compositions of cannabinoids for delivery by inhalation |
Citations (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JPH07213608A (ja) * | 1994-01-25 | 1995-08-15 | Becton Dickinson & Co | 注射器組立体 |
US6752292B2 (en) * | 2000-12-06 | 2004-06-22 | Illbruck Gmbh | Cartridge set for dispensing in-situ foam |
WO2006073505A2 (en) * | 2004-12-30 | 2006-07-13 | Integrity Biosolution, Llc | Container closure delivery system |
Family Cites Families (66)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US2708438A (en) * | 1951-11-13 | 1955-05-17 | Miljam Instr Corp | Hypodermic syringe |
US3342180A (en) * | 1964-04-24 | 1967-09-19 | American Cyanamid Co | Disposable liquid-powder package and hypodermic syringe |
US3477432A (en) | 1964-07-21 | 1969-11-11 | Joseph Denman Shaw | Combination mixing and injecting medical syringe |
US3330280A (en) * | 1964-08-25 | 1967-07-11 | Duo Matic Corp | Combination syringe vial and plunger and syringe |
US3766917A (en) | 1968-01-26 | 1973-10-23 | West Co | Two compartment ampul syringe |
AT318132B (de) | 1969-08-01 | 1974-09-25 | Dentaire Ivoclar Ets | Mischbehälter für die Aufnahme von miteinander reagierenden Substanzen für die Herstellung von gebrauchsfertigen pastenförmigen Dentalpräparaten |
US3685514A (en) | 1969-09-23 | 1972-08-22 | Paul E Cheney | Two compartment syringe |
US3678514A (en) * | 1970-01-21 | 1972-07-25 | Hanes Corp | Combination garments and method of making same |
US3678931A (en) | 1970-06-09 | 1972-07-25 | Milton J Cohen | Syringe |
US3838689A (en) | 1970-11-04 | 1974-10-01 | M Cohen | Disposable syringe with slit valve |
US3826260A (en) | 1971-12-27 | 1974-07-30 | Upjohn Co | Vial and syringe combination |
US4041945A (en) * | 1976-06-07 | 1977-08-16 | Guiney Aeneas C | Mixing syringe |
US4153186A (en) | 1977-07-20 | 1979-05-08 | Arthur T. Medkeff | Valve and medicant dispensing syringe |
US4172457A (en) | 1977-10-06 | 1979-10-30 | American Hospital Supply Corporation | Plural component mixing system and method |
US4318386A (en) | 1979-09-20 | 1982-03-09 | Automotive Engine Associates | Vortex fuel air mixer |
US4328802A (en) | 1980-05-14 | 1982-05-11 | Survival Technology, Inc. | Wet dry syringe package |
US4458733A (en) | 1982-04-06 | 1984-07-10 | Baxter Travenol Laboratories, Inc. | Mixing apparatus |
US4410321A (en) | 1982-04-06 | 1983-10-18 | Baxter Travenol Laboratories, Inc. | Closed drug delivery system |
ATE31481T1 (de) * | 1984-01-25 | 1988-01-15 | Medicorp Holding | Vorgefuellte injektionsspritze fuer einheitliche dosierung. |
WO1986007541A1 (en) | 1985-06-19 | 1986-12-31 | Yasushi Zyo | Composition which can impart antithrombotic ability and medical apparatus to be in contact with blood |
US4886495A (en) * | 1987-07-08 | 1989-12-12 | Duoject Medical Systems Inc. | Vial-based prefilled syringe system for one or two component medicaments |
US4898209A (en) | 1988-09-27 | 1990-02-06 | Baxter International Inc. | Sliding reconstitution device with seal |
ATE90211T1 (de) | 1990-02-07 | 1993-06-15 | Vetter & Co Apotheker | Doppelkammerspritze und verwendungsverfahren. |
DK288590D0 (da) | 1990-12-04 | 1990-12-04 | Michael Morris | Blandings/oploesnings-sproejte til cytostatika for medicinsk behandling af cancer patienter |
SE9201247D0 (sv) | 1992-04-21 | 1992-04-21 | Kabi Pharmacia Ab | Injection device |
SE9201246D0 (sv) | 1992-04-21 | 1992-04-21 | Kabi Pharmacia Ab | Injection cartridge arrangement |
AU665067B2 (en) | 1992-04-30 | 1995-12-14 | Takeda Pharmaceutical Company Limited | Prefilled syringe |
US5817055A (en) | 1992-07-07 | 1998-10-06 | Pharmacia & Upjohn Aktiebolag | Dual-chamber injection cartridge |
SE9202108D0 (sv) | 1992-07-07 | 1992-07-07 | Kabi Pharmacia Ab | Dual-chamber injection cartridge |
DE69508629T2 (de) | 1994-01-25 | 1999-10-14 | Becton Dickinson Co | Spritze und Verfahren zur Lyophilisierung und Wiederherstellung von einspritzbaren Medikamenten |
US5496284A (en) | 1994-09-27 | 1996-03-05 | Waldenburg; Ottfried | Dual-chamber syringe & method |
US5685846A (en) | 1995-02-27 | 1997-11-11 | Schott Parenta Systems, Inc. | Dual chamber internal by-pass syringe assembly |
US5785682A (en) | 1995-03-22 | 1998-07-28 | Abbott Laboratories | Pre-filled syringe drug delivery system |
US5569193A (en) | 1995-03-22 | 1996-10-29 | Abbott Laboratories | Syringe system accommodating separately storable prefilled containers for two constituents |
US5876372A (en) | 1995-03-22 | 1999-03-02 | Abbott Laboratories | Syringe system accomodating seperate prefilled barrels for two constituents |
US5779668A (en) | 1995-03-29 | 1998-07-14 | Abbott Laboratories | Syringe barrel for lyophilization, reconstitution and administration |
GB9611562D0 (en) | 1996-06-03 | 1996-08-07 | Applied Research Systems | Device |
US5865798A (en) | 1996-06-28 | 1999-02-02 | Becton Dickinson France, S.A. | Stopper assembly having bypass features for use in a multi-chamber syringe barrel |
US7387216B1 (en) | 1996-07-17 | 2008-06-17 | Smith James C | Closure device for containers |
DE19638940C2 (de) | 1996-09-23 | 1999-01-07 | Vetter & Co Apotheker | Vorgefüllte Spritze für medizinische Zwecke |
US6171276B1 (en) | 1997-08-06 | 2001-01-09 | Pharmacia & Upjohn Ab | Automated delivery device and method for its operation |
US6458095B1 (en) | 1997-10-22 | 2002-10-01 | 3M Innovative Properties Company | Dispenser for an adhesive tissue sealant having a housing with multiple cavities |
SE9704405D0 (sv) | 1997-11-28 | 1997-11-28 | Pharmacia & Upjohn Ab | New syringe |
US6019750A (en) | 1997-12-04 | 2000-02-01 | Baxter International Inc. | Sliding reconstitution device with seal |
JP2951938B1 (ja) | 1998-03-19 | 1999-09-20 | 日本ケミカルリサーチ株式会社 | 薬剤溶解機構を内蔵した注射器 |
US6149628A (en) | 1998-07-20 | 2000-11-21 | Szapiro; Jaime Luis | Syringe with two variable volume chambers for containing and administering mixtures of products provided separately |
US6514231B1 (en) | 1998-07-20 | 2003-02-04 | Jaime Luis Szapiro | Disposable syringe with single variable volume chamber |
US20050137566A1 (en) | 2003-12-23 | 2005-06-23 | Fowles Thomas A. | Sliding reconstitution device for a diluent container |
US6406455B1 (en) | 1998-12-18 | 2002-06-18 | Biovalve Technologies, Inc. | Injection devices |
DE19912322A1 (de) | 1999-03-19 | 2000-09-28 | Vetter & Co Apotheker | Spritze für medizinische Zwecke |
FR2799654B1 (fr) * | 1999-10-13 | 2002-01-11 | Sod Conseils Rech Applic | Dispositif pour reconstituer une solution, une suspension ou une dispersion therapeutique et procede de preparation et de conditionnement dans ce dispositif |
US6440101B1 (en) | 2000-05-31 | 2002-08-27 | Abbott Laboratories | Syringe systems for lyophilized drugs and methods for making the same |
US6386872B1 (en) | 2001-01-03 | 2002-05-14 | Gc Corporation | Capsule for dental restoration material |
DE10140704A1 (de) | 2001-08-18 | 2003-03-06 | Vetter & Co Apotheker | Verfahren zur Durchmischung einer schwer löslichen pharmazeutischen Substanz mit einem Lösungsmittel und Spritze zur Anwendung des Verfahrens |
US6808511B2 (en) | 2001-10-11 | 2004-10-26 | Gary J. Pond | Disposable aspirating safety syringe |
JP4112851B2 (ja) * | 2001-11-27 | 2008-07-02 | テルモ株式会社 | 2室型プレフィルドシリンジ |
EP1344500B1 (de) * | 2002-03-15 | 2005-06-01 | Ernst Mühlbauer GmbH & Co.KG | Mehrkomponenten-Mischkapsel, insbesondere für Dentalzwecke |
US6743194B2 (en) | 2002-03-28 | 2004-06-01 | Igal Sharon | Multi-compartment syringe |
US6884232B1 (en) | 2003-10-31 | 2005-04-26 | Baxter International Inc. | Laparoscopic spray device and method of use |
US7470253B2 (en) | 2004-05-26 | 2008-12-30 | Bioquiddity, Inc. | Fluid delivery apparatus with adjustable flow rate control |
EP1602415A1 (en) * | 2004-06-04 | 2005-12-07 | 3M Espe AG | Syringe for a multi-component paste |
US7329235B2 (en) | 2004-08-02 | 2008-02-12 | Bertron Kim W | Powder and liquid mixing syringe |
US7959600B2 (en) | 2004-12-30 | 2011-06-14 | Byeong S. Chang | Container closure delivery system |
US20060157507A1 (en) | 2004-12-30 | 2006-07-20 | Chang Byeong S | Multi-functional container closure delivery system |
AR076716A1 (es) | 2009-06-02 | 2011-06-29 | Sanofi Aventis Deutschland | Modulo medicado con medicamento de premezcla |
EP2663275B1 (en) | 2011-01-10 | 2017-03-08 | Byeong Seon Chang | Compact medication reconstitution device and method |
-
2007
- 2007-03-09 US US11/716,223 patent/US7959600B2/en active Active
-
2008
- 2008-03-07 KR KR1020097021010A patent/KR101288174B1/ko active IP Right Grant
- 2008-03-07 EP EP14159997.7A patent/EP2743654A3/en not_active Withdrawn
- 2008-03-07 CA CA2679431A patent/CA2679431C/en active Active
- 2008-03-07 EP EP08726576.5A patent/EP2134641B1/en active Active
- 2008-03-07 AU AU2008226938A patent/AU2008226938B2/en active Active
- 2008-03-07 MX MX2009009474A patent/MX2009009474A/es active IP Right Grant
- 2008-03-07 WO PCT/US2008/003065 patent/WO2008112155A1/en active Application Filing
- 2008-03-07 ES ES08726576.5T patent/ES2500494T3/es active Active
- 2008-03-07 JP JP2009552748A patent/JP5255002B2/ja not_active Expired - Fee Related
-
2011
- 2011-06-13 US US13/159,346 patent/US8579855B2/en active Active
-
2013
- 2013-02-21 JP JP2013031955A patent/JP5827966B2/ja active Active
- 2013-09-22 US US14/033,498 patent/US9174002B2/en not_active Expired - Fee Related
-
2014
- 2014-12-18 HK HK14112686.8A patent/HK1199300A1/xx unknown
Patent Citations (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JPH07213608A (ja) * | 1994-01-25 | 1995-08-15 | Becton Dickinson & Co | 注射器組立体 |
US6752292B2 (en) * | 2000-12-06 | 2004-06-22 | Illbruck Gmbh | Cartridge set for dispensing in-situ foam |
WO2006073505A2 (en) * | 2004-12-30 | 2006-07-13 | Integrity Biosolution, Llc | Container closure delivery system |
Cited By (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
TWI817611B (zh) * | 2022-07-15 | 2023-10-01 | 陳昌慈 | 凍乾粉針劑還原器 |
Also Published As
Publication number | Publication date |
---|---|
KR101288174B1 (ko) | 2013-07-18 |
CA2679431C (en) | 2015-07-07 |
EP2134641B1 (en) | 2014-07-30 |
EP2743654A2 (en) | 2014-06-18 |
JP5827966B2 (ja) | 2015-12-02 |
KR20100015431A (ko) | 2010-02-12 |
JP5255002B2 (ja) | 2013-08-07 |
CA2679431A1 (en) | 2008-09-18 |
EP2134641A1 (en) | 2009-12-23 |
US20110288531A1 (en) | 2011-11-24 |
AU2008226938A1 (en) | 2008-09-18 |
US7959600B2 (en) | 2011-06-14 |
HK1199300A1 (en) | 2015-06-26 |
US20070225640A1 (en) | 2007-09-27 |
US8579855B2 (en) | 2013-11-12 |
JP2010520782A (ja) | 2010-06-17 |
EP2743654A3 (en) | 2015-10-21 |
EP2134641A4 (en) | 2011-08-24 |
ES2500494T3 (es) | 2014-09-30 |
US9174002B2 (en) | 2015-11-03 |
AU2008226938B2 (en) | 2012-10-18 |
MX2009009474A (es) | 2010-02-18 |
US20140025040A1 (en) | 2014-01-23 |
WO2008112155A1 (en) | 2008-09-18 |
Similar Documents
Publication | Publication Date | Title |
---|---|---|
JP5827966B2 (ja) | 容器閉鎖配送システム | |
JP4960259B2 (ja) | 密閉容器送出システム | |
US10624815B2 (en) | Compact medication reconstitution device and method | |
US20060157507A1 (en) | Multi-functional container closure delivery system |
Legal Events
Date | Code | Title | Description |
---|---|---|---|
A621 | Written request for application examination |
Free format text: JAPANESE INTERMEDIATE CODE: A621 Effective date: 20130322 |
|
A977 | Report on retrieval |
Free format text: JAPANESE INTERMEDIATE CODE: A971007 Effective date: 20140131 |
|
A131 | Notification of reasons for refusal |
Free format text: JAPANESE INTERMEDIATE CODE: A131 Effective date: 20140401 |
|
RD02 | Notification of acceptance of power of attorney |
Free format text: JAPANESE INTERMEDIATE CODE: A7422 Effective date: 20140620 |
|
A601 | Written request for extension of time |
Free format text: JAPANESE INTERMEDIATE CODE: A601 Effective date: 20140625 |
|
A521 | Request for written amendment filed |
Free format text: JAPANESE INTERMEDIATE CODE: A523 Effective date: 20140709 |
|
A521 | Request for written amendment filed |
Free format text: JAPANESE INTERMEDIATE CODE: A523 Effective date: 20140731 |
|
RD04 | Notification of resignation of power of attorney |
Free format text: JAPANESE INTERMEDIATE CODE: A7424 Effective date: 20140723 |
|
A521 | Request for written amendment filed |
Free format text: JAPANESE INTERMEDIATE CODE: A523 Effective date: 20140731 |
|
A602 | Written permission of extension of time |
Free format text: JAPANESE INTERMEDIATE CODE: A602 Effective date: 20140818 |
|
A131 | Notification of reasons for refusal |
Free format text: JAPANESE INTERMEDIATE CODE: A131 Effective date: 20150120 |
|
A521 | Request for written amendment filed |
Free format text: JAPANESE INTERMEDIATE CODE: A523 Effective date: 20150401 |
|
TRDD | Decision of grant or rejection written | ||
A01 | Written decision to grant a patent or to grant a registration (utility model) |
Free format text: JAPANESE INTERMEDIATE CODE: A01 Effective date: 20150929 |
|
A61 | First payment of annual fees (during grant procedure) |
Free format text: JAPANESE INTERMEDIATE CODE: A61 Effective date: 20151019 |
|
R150 | Certificate of patent or registration of utility model |
Ref document number: 5827966 Country of ref document: JP Free format text: JAPANESE INTERMEDIATE CODE: R150 |
|
R250 | Receipt of annual fees |
Free format text: JAPANESE INTERMEDIATE CODE: R250 |
|
R250 | Receipt of annual fees |
Free format text: JAPANESE INTERMEDIATE CODE: R250 |
|
R250 | Receipt of annual fees |
Free format text: JAPANESE INTERMEDIATE CODE: R250 |
|
R250 | Receipt of annual fees |
Free format text: JAPANESE INTERMEDIATE CODE: R250 |
|
R250 | Receipt of annual fees |
Free format text: JAPANESE INTERMEDIATE CODE: R250 |