JP2013066863A - Micromixer and microreactor including the same - Google Patents

Abstract

PROBLEM TO BE SOLVED: To provide a micromixer maintaining and improving the mixing efficiency of a plurality of fluids while reducing pressure loss when supplying the plurality of fluids into flow passages, and to provide a microreactor including the same.SOLUTION: In this micromixer, a shaft body 4 is inserted into an axially long circular hole 3 formed in a body part 2, and flow passages for mixing the plurality of kinds of fluids while making the plurality of kinds of fluids flow in the shaft direction are formed in gaps between the inner circumferential surface 5 of the circular hole 3 and the outer circumferential surface 6 of the shaft body 4. The micromixer includes: a plurality of main flow passages 7a, 7b extending along the shaft direction parallel to each other; and a plurality of sub flow passages 8a-8g each extending in an oblique direction to the shaft direction and communicating the main flow passages with each other. By repeating that the fluids flowing through the main flow passages 7a, 7b are made to be branched/joined with the fluids of the other main flow passages 7b, 7a through the sub flow passages 8a-8g, the plurality of kinds of fluids are mixed.

Description

  The present invention relates to a micromixer and a microreactor including the same.

  This type of micromixer and a microreactor including the micromixer (hereinafter sometimes referred to as “micromixer”) include a micro flow channel having a width of 1 mm or less for mixing a plurality of fluids, etc. , Precise temperature control based on the size of the specific surface area is possible, precise mixing control based on molecular diffusion between stable laminar flow interfaces is possible, reaction time can be controlled by precise control of residence time in the microchannel, etc. It is said to have characteristics. In recent years, micromixers and the like have been used for the purpose of performing chemical synthesis, creation of new substances, analysis of various samples, and the like using these characteristics.

  As described above, in a micromixer or the like, generally, mixing control based on molecular diffusion between stable laminar flow interfaces is used. This is based on the fact that molecular diffusion mixing between laminar flow interfaces in a micro space is overwhelmingly faster than mixing between interfaces in a macro space. However, even in a micro space, since molecular diffusion occurs due to a concentration gradient or the like, molecular diffusion mixing may take time. For this reason, there are problems such that it takes time to obtain a desired mixed state and reactant, and it is necessary to provide a longer flow path.

  As a countermeasure, a micromixer that generates turbulent flow in a microchannel and improves mixing efficiency and reaction efficiency has been proposed (Patent Documents 1 to 3). In Patent Document 1, a method of disposing an obstacle that can be deformed and / or operated in the flow path, in Patent Document 2, a method of forming a spiral uneven portion on the inner wall surface of the flow path, in Patent Document 3 A method of arranging a baffle plate, an impeller, a spiral fixed wing, a propeller and the like in the flow path has been proposed.

  However, the obstacles of Patent Document 1, the impellers, propellers, and the like of Patent Document 3 have a complicated structure, and there is a possibility that sufficient mixing efficiency cannot be ensured in a portion where there are no obstacles. Moreover, although the helical uneven | corrugated | grooved part, the baffle plate, and the spiral fixed wing | blade of patent document 3 can be distribute | arranged over the full length of a flow path, the mixing efficiency is improved on the inner wall face of the flow path of patent document 2 For this reason, when the flow rate is increased, the pressure loss increases and liquid feeding may be difficult. When attempting to reduce the pressure loss, there is a problem that the mixing efficiency is decreased.

JP 2006-7007 A JP 2006-142210 A JP 2007-252979 A

  In view of the above problems, the object of the present invention is to maintain and improve the mixing efficiency of a plurality of fluids while reducing the pressure loss when supplying a plurality of fluids to a flow path. The object is to provide a micromixer and a microreactor including the same.

  As a result of intensive studies, the inventors have identified the structure of the flow path formed in the gap between the inner peripheral surface of the round hole formed in the main body portion and the outer surface of the shaft body attached to the round hole. The present inventors have found that the above problems can be solved when the structure is adopted, and have completed the present invention. That is, the gist of the present invention is as follows.

(1) A shaft body is inserted into an axially long round hole formed in the main body, and a plurality of kinds of fluids are allowed to flow in the axial direction through a gap between the inner peripheral surface of the round hole and the outer surface of the shaft body. A micromixer formed with a channel to be mixed,
A plurality of main flow paths extending parallel to each other along the axial direction;
A plurality of sub-channels extending in an oblique direction with respect to the axial direction and communicating between the main channels;
A micromixer characterized in that the plurality of types of fluids are mixed by repeatedly branching / merging the fluid in another main channel through the sub-channel with the fluid flowing in the main channel.
(2) The plurality of main flow paths are formed of a plurality of parallel cutout grooves formed on the outer surface of the shaft body at intervals in the circumferential direction, and the sub-flow path is also formed outside the shaft body. The micromixer according to (1), comprising a single or a plurality of concave grooves formed on the surface and extending spirally while intersecting the notch grooves.
(3) A mounting hole for mounting the shaft body is provided in the main body portion so as to communicate with the upstream axial direction of the round hole, and is opened at a position corresponding to the upstream portion of each main flow path of the round hole. The micromixer according to (1) or (2), wherein a plurality of supply paths for supplying fluid to the main flow path are provided.
(4) A microreactor comprising the micromixer according to any one of (1) to (3).

  In general, a micromixer means an apparatus for mixing a plurality of fluids, and a microreactor means an apparatus for performing a chemical reaction by diffusing and mixing a plurality of fluids. The micromixers and microreactors in the present invention also follow these general definitions.

  The above-described micromixer according to the present invention can maintain and improve the mixing efficiency of a plurality of fluids while reducing the pressure loss when supplying the plurality of fluids to the flow path. As a result, a microreactor including the micromixer according to the present invention can be expected to maintain and improve the reaction efficiency and the like of substances contained in a plurality of fluids while reducing pressure loss.

It is a fragmentary sectional view of the horizontal surface direction parallel to an axial direction which shows an example of embodiment of the micro mixer of this invention. (A) It is an enlarged view of the flow path in FIG. (B) It is a fragmentary sectional view of the direction perpendicular | vertical to the axial direction of the AA part in Fig.2 (a). It is explanatory drawing which showed the structure for measuring the pressure loss of a micro mixer.

  Next, embodiments of the present invention will be described with reference to the accompanying drawings.

  FIG. 1 is a partial cross-sectional view in the horizontal direction parallel to the axial direction, showing an example of an embodiment of the micromixer of the present invention. 2A is an enlarged view of the flow path portion in FIG. 1, and FIG. 2B is a partial cross-sectional view in a direction perpendicular to the axial direction of the AA portion in FIG. 2A. is there.

  In the example of the present embodiment, as shown in FIG. 1, the micromixer 1 is provided with a long circular hole 3 in the axial direction in the main body 2, and a shaft body 4 is attached to the round hole 3.

  A flow path for mixing a plurality of types of fluids while flowing in the axial direction is formed in a gap between the inner peripheral surface 5 of the round hole 3 and the outer surface 6 of the shaft body 4 as shown in FIG. Yes. This flow path is composed of a plurality of main flow paths and a plurality of sub flow paths. Further, the round hole 3 and the shaft body 4 are mounted in a slidable state, and are in close contact with each other so that substantially no fluid flows except for this flow path.

  The plurality of main flow paths extend in parallel with each other along the axial direction of the round hole 3, and in this example, two are provided as indicated by reference numerals 7a and 7b. However, the number of main flow paths is not limited to two as in this example, and may be three or more according to the number of fluids to be mixed. Moreover, in this example, the main flow paths 7a and 7b are formed by parallel cutout grooves 9a and 9b formed on the outer surface of the shaft body 4 with a circumferential interval. When three or more main flow paths are provided, three or more notch grooves are preferably provided. Further, the circumferential interval is not particularly limited, and it may be provided so that the intermediate portions in the circumferential direction of the cutout grooves are equidistant, or may be provided so as not to be equidistant. In addition, the cross-sectional shape of the notch groove is not particularly limited, and in this example, as shown in FIG. 2B, the notch portion is configured to be a straight line in the cross section perpendicular to the axial direction. You may comprise so that it may become an arcuate curve. Also, the structure of the plurality of cutout grooves may be the same shape or different shapes. The size of the notch groove is not particularly limited as long as pressure loss can be reduced and mixing efficiency can be maintained, but the cross-sectional area of each main channel (notch groove) (in the direction perpendicular to the axial direction of the shaft body 4) is not limited. The shaft body so that the cross-section (hereinafter the same) is about 6 to 15% of the cross-sectional area of the round hole 3 for mounting the shaft body 4 (the cross-section perpendicular to the axial direction of the round hole 3, the same applies hereinafter). It is preferable to set the width and depth at 4. In addition, the width and depth are set so that the total cross-sectional area of the main flow path in one cross section where the main flow path exists is approximately 6 to 30% of the cross-sectional area of the round hole 3 for mounting the shaft body 4. It is preferable to do this. Further, the width of the main channel may be set so as to satisfy the above cross-sectional area within a range that functions as a micromixer or a microreactor, and can be set to, for example, 0.3 to 2 mm. The width is the maximum width of the notch groove in the shaft body 4, and the depth is the maximum distance when the shaft body 4 is not cut out from the center axis and the portion cut out from the center axis of the shaft body 4. Is the difference from the shortest distance.

  The plurality of sub-channels extend obliquely with respect to the axial direction so as to communicate between the main channels. In this example, seven sub-channels are provided as indicated by reference numerals 8a to 8g. And subchannel 8a-d is extended in the slanting direction from the upper right direction of Drawing 2 (a) to the lower left direction. In addition, the auxiliary flow paths 8e to 8g are formed on the outer surface 6 opposite to the outer surface 6 provided with the auxiliary flow paths 8a to 8d in an oblique direction from the upper left direction to the lower right direction in FIG. It is growing. In this example, the auxiliary flow paths 8a to 8g are formed on the outer surface 6 of the shaft body 4 and are formed of a single concave groove 10 extending spirally while intersecting the notch grooves 9a and 9b. Yes. That is, in this example, a single spiral is formed so as to form a single (single) spiral sub-flow path starting from the sub-flow path 8a and sequentially continuing to 8e, 8b, 8f, 8c, 8g, and 8d. A concave groove 10 extending in a shape is formed. In this example, an example in which the single concave groove 10 is formed in the shaft body 4 is shown. However, the concave groove may be provided so as to form a double spiral, or three or more A spiral groove may be provided. Further, the pitch interval of the spirals (number of sub-channels) can be appropriately determined in consideration of pressure loss and mixing efficiency. Furthermore, in this example, an example in which the sub-channel has a spiral shape as a whole has been shown, but it does not have to be a spiral shape as a whole.

  In addition, the cross-sectional shape of the groove is not particularly limited, and in this example, as shown in FIG. 2B, it is configured to have an arcuate curve in a cross section perpendicular to the axial direction. However, it is not limited to this. Further, the groove grooves constituting the plurality of sub flow paths may have different shapes or the same shape in each sub flow path. The size of the groove is not particularly limited as long as the pressure loss can be reduced and the mixing efficiency can be maintained and improved. However, the cross-sectional area of each sub-flow channel is the round hole 3 for mounting the shaft body 4. The width and depth of the shaft body 4 are preferably set so as to be about 0.6 to 3.5% of the cross-sectional area. When two or more sub-channels are formed in the same cross section, the total cross-sectional area thereof is about 0.6 to 6.7% of the cross-sectional area of the round hole 3 for mounting the shaft body 4. Thus, it is preferable to set the width and depth. The width is the maximum width of the groove groove in the shaft body 4, and the depth is the maximum distance when the groove groove is not provided from the central axis of the shaft body 4, and the groove groove from the center axis. It is the difference with the shortest distance to.

  By configuring the main flow path and the sub flow path as described above, it is possible to efficiently branch and join the fluid flowing in the main flow path through the sub flow path to the fluid of the other main flow path so that a plurality of types of fluid can be efficiently used. Furthermore, it is possible to reduce the pressure loss when supplying the fluid.

  The sizes of the round hole 3 and the shaft body 4 may be appropriately determined according to the type of fluid and the mixing characteristics. The material of the shaft body 4 is not particularly limited, and synthetic resin, ceramic, glass, metal, and the like can be used. From the viewpoint of workability and corrosivity, stainless steel, nickel-based alloy, and the like are preferable. . Examples of such stainless steel include austenitic stainless steels such as SUS304 and SUS316, and examples of nickel-based alloys include Hastelloy (registered trademark).

Further, in this example, the shaft body 4 is fitted and fixed to the adapter 12 having an outer diameter larger than that of the shaft body 4 from the viewpoint of securing the mounting property to the main body portion 2, and is attached to the main body portion 2 via the adapter 12. It is fixed. However, the adapter 12 may not be used depending on the configuration and size of the shaft body 4. Further, in this example, as shown in FIG. 1, a male screw portion 13 for fixing to the main body portion 2 is provided on the outer peripheral portion of the adapter 12.
By adopting such a configuration, the main body 2 and the shaft body 4 can be attached and detached, and the operation thereof becomes easy. Therefore, it is easy to clean the shaft body 4 and the round hole 3 of the main body part 2 after the reaction is completed. When the shaft body 4 is damaged, the main body part 3 etc. can be reused as it is simply by replacing the shaft body 4. Is possible.

  As shown in FIGS. 1 and 2, the main body 2 is provided with a round hole 3 for mounting the shaft body 4. The inner diameter and the axial length of the round hole 3 can be appropriately determined according to the shaft body 4. In this example, a mounting hole 11 for mounting the shaft body 4 is provided in communication with the axial direction upstream of the round hole 3. The mounting hole 11 is provided with an opening 14 through which the shaft body 4 can be inserted in close contact so that fluid does not substantially leak, and the adapter 12 receives the adapter 12 and is screwed into and fixed to the male screw portion 13 of the adapter 12. Are provided on the inner peripheral surface thereof.

The main body 2 is provided with supply passages 16a and 16b for supplying fluid to the main passages 7a and 7b, which are opened at positions corresponding to the upstream portions of the main passages 7a and 7b of the round hole 3, respectively. It has been. In this example, the case where there are two supply paths is shown, but when three or more main flow paths are provided, three or more supply paths may be provided.
In this example, the supply paths 16a and 16b are configured to supply the respective fluids directly to the main flow paths 7a and 7b, respectively. A portion (space) may be provided, and the mixed fluid may flow from the merging portion to the main flow path and the sub flow path. In addition, as a junction part, it can form by providing an annular notch part in the outer surface of the shaft body 4 of the part close | similar to supply path 16a, 16b, for example.

  Further, the main body 2 is provided with supply holes 17a and 17b, and connectors 18a and 18b for connecting an introduction pipe (not shown) for supplying a desired fluid from the outside can be connected. In this example, the supply holes 17 a and 17 b are arranged so as to be orthogonal to the round hole 3 in a T shape, but may be arranged in a Y shape. Further, male screw portions 19a and 19b are provided on the outer peripheral portions of the connectors 18a and 18b, respectively, and female screw portions 20a and 20b are provided on the inner peripheral surfaces of the supply holes 17a and 17b, respectively. The male screw portion and the female screw portion are screwed. It can be fixed together. In addition, supply paths 16a and 16b are provided in the connectors 18a and 18b, respectively, so that the supply paths 16a and 16b of the main body 2 and the introduction pipe communicate with each other. FIG. 1 shows a part of the connectors 18a and 18b and does not show a connection structure with the introduction pipe, but a structure generally used in this technical field can be adopted.

  Further, in the example shown in FIG. 2, a discharge passage 21 is provided downstream of the round hole 3 of the main body portion 2, and the fluid flowing through the main passages 7 a and 7 b is supplied to the fluid of other main passages through the sub-passages 8 a to 8 k. The mixed fluid is discharged by repeating the branching / merging.

  In addition, the main body 2 is provided with a discharge hole 22 so that a connector 23 for connecting a discharge pipe (not shown) for discharging the mixed fluid to the outside can be connected. The connector 23 is provided with a male screw portion 24, and the discharge hole 22 is provided with a female screw portion 25 so that the male screw portion and the female screw portion can be screwed together to be fixed. Further, a discharge path 21 is also provided in the connector 23 so that the discharge path 21 of the main body 2 and the discharge pipe communicate with each other. Although FIG. 1 shows a part of the connector 23 and does not show a connection structure with the discharge pipe, a structure generally used in this technical field can be adopted.

  The size, shape, and structure of the main body 2 are not particularly limited. For example, a structure that can be divided into two parts in the cross section of the main body 2 as shown in FIG. 1 may be used, or a structure that has a structure that cannot be divided and that has a round hole 3, supply paths 16a, 16b, and the like.

  The material that can be used for the main body 2, the adapter 12, and the connectors 18 a, 18 b, and 23 is not particularly limited, and can be appropriately selected in consideration of the characteristics of the fluid to be used and the product when there is a reaction. . For example, various materials such as synthetic resin, glass, ceramic, and metal can be used. From the viewpoint of workability and corrosiveness, stainless steel, nickel-base alloy, and the like are preferable. Examples of such stainless steel include austenitic stainless steels such as SUS304 and SUS316, and examples of nickel-based alloys include Hastelloy (registered trademark). Further, when the inside of the round hole 3 of the main body 2 is viewed from the outside, a transparent material such as glass or transparent synthetic resin is applied to the entire main body 2 or a portion where the round hole 3 is present, depending on the type of fluid. It is good to provide.

  Moreover, the embodiment of the microreactor according to the present invention includes the above-described micromixer according to the present invention. The configuration other than the micromixer in the microphone reactor is not particularly limited, and can be appropriately selected according to the use of the microreactor. For example, fluid supply means such as a pump and a syringe for supplying various fluids, a raw material fluid storage tank for storing various fluids, and a mixed liquid storage tank for storing mixed or reacted fluid discharged from a micromixer Examples include, but are not limited to, a reactor for reacting the mixed fluid discharged from the micromixer, a control means such as a computer for controlling the flow rate and reaction conditions of the fluid supply means, and the like.

The micromixer according to the present invention as described above can efficiently mix a plurality of fluids while reducing pressure loss. In addition, a microreactor including the micromixer according to the present invention can maintain and improve the reaction efficiency and the like because a plurality of fluids are efficiently mixed while reducing pressure loss in the micromixer. In addition, the fluid used in the micromixer and the microreactor may be gas or liquid, and there is no particular limitation on the type thereof. Furthermore, when using a plurality of fluids, only gas, only liquid, or a combination of gas and liquid may be used.
Therefore, the micromixer and the microreactor according to the present invention can be suitably used for development of synthesis technology and chemical manufacturing technology, detection and analysis of trace components.

  Below, the micromixer of this invention is demonstrated in detail based on an Example.

Example 1
As shown in FIG. 1, a round hole (about φ0.5 mm × length 9 mm) is formed in a main body (2) made of a nickel base alloy (HASTELLOY (registered trademark)) (hereinafter simply referred to as “nickel base alloy”). 3) and two supply paths (16a, 16b) of about φ0.5 mm were provided in a T shape. In addition, a portion where the shaft body (4) is not disposed is left about 1.8 mm on the downstream side of the round hole (3) to form a discharge path (21). Further, a mounting hole (11) having an opening (14) of about φ0.5 mm for mounting the shaft body (4) was provided in the axial direction upstream of the round hole (3). In addition, a supply path of about φ0.4 mm communicating with the supply path (16a, 16b) of the main body (2) is provided inside the nickel-base alloy connector (18a, 18b) to supply the main body (2). Screwed into the hole (7). The nickel base alloy connector (23) is provided with a discharge path (21) of about φ0.5 mm communicating with the round hole (3) and screwed into the discharge hole (22) of the main body (2). .
In the shaft body (4), the length of the portion arranged in the round hole (3) is 7 mm, the maximum width is about 0.5 mm, and the depth of the notch groove constituting the main flow path is about 0.08 mm (round hole). (The cross-sectional area of the main flow path is approximately 10.3% of the cross-sectional area of the round hole, the total is approximately 20.6%), and constitutes a sub-flow path. The concave groove was formed in a double spiral shape having a depth of about 0.13 mm, a width of about 0.3 mm, and a pitch interval of 0.5 mm (each cross-sectional area of the sub-channel is about 1 of the cross-sectional area of the round hole). 0.2%, about 2.4% in total). (Note that this embodiment differs from the embodiment shown in FIGS. 1 and 2 in that a double spiral groove is formed in the shaft body (4).)
After the shaft body (4) is fitted and fixed to the adapter (12), the shaft body (4) is inserted from the mounting hole (14) and the opening (11) of the main body (2), and the round hole (3) The shaft body (4) was mounted therein, and the adapter (12) was screwed into the mounting hole (11) to produce a micromixer.

(Comparative Example 1)
A micromixer was produced in the same manner as in Example 1 except that a shaft body having no notch was used.

(Evaluation 1) Evaluation of mixing performance Using the micromixers produced in Example 1 and Comparative Example 1, the mixing performance of two liquids was evaluated. The evaluation was performed by Ehrfeld method based on the Villermuux / Dushman reaction of two miscible fluids (liquid A and liquid B), and the absorption of UV spectrometry was measured at 352 nm (I ₃ ⁻ ) within 15 seconds. . Specifically, HCl solution (137.4 mmol / l) is used as solution A, KI is 16 mmol / l, KIO ₃ is 3.18 mmol / l, and CH ₃ COONa is 1.330 mol / l as solution B. Was supplied to the micromixer at the synthesis flow rate shown in Table 1 so that the flow rate ratio (A: B) was 1: 1. The UV absorbance (λ = 352 nm) of I ₃ ⁻ was measured, and the mixing performance of the micromixer was evaluated. The principle is as follows.

CH ₃ COO ⁻ + H ⁺ → CH ₃ COOH (1)
5I ⁻ + IO ₃ ⁻ + 6H ⁺ → 3I ₂ + 3H ₂ O (2)
^{_{I 2 + I - → I 3}} - (3)
Although the reactions of the above formulas (1) and (2) are both rapid, the reaction (1) is the most rapid. The faster the mixing, the less I ₂ and I ₃ ⁻ are produced. Therefore, the lower the I ₃ ⁻ UV absorbance, the better the mixing. The evaluation results are shown in Table 1.

(Evaluation 2) Measurement of pressure loss Liquid A and liquid B were used in the same manner as in evaluation 1, liquid A and liquid B were fed under the same conditions, and liquid A was measured using the measurement system shown in FIG. The pressure loss was measured by measuring the differential pressure on the upstream side and the downstream side where the mixed liquid of liquid A and liquid B was discharged. The evaluation results are shown in Table 1.
The measurement system 33 shown in FIG. 3 will be briefly described. The measurement system 33 includes a micromixer 32, a liquid A storage tank 26, a liquid B storage tank 27, a liquid storage tank 31 of a mixed liquid of liquid A and liquid B, liquid A and liquid B, which are prepared in the examples and comparative examples. A pump 28 for feeding the liquid to the mixer 32, an orifice 29 for detecting the pressure on the upstream side and the downstream side of the micromixer 32, and a manometer for measuring the differential pressure between the pressures detected by the upstream and downstream orifices 29 (Pressure gauge) 30 and a pipe.
The pipe from the A liquid storage tank 26 is connected to a connector (18b) (not shown) of the micromixer 32, and the A liquid is fed to a supply path (16b) (not shown). Similarly, the pipe from the B liquid storage tank 27 is connected to a connector (18a) (not shown) of the micromixer 32, and the B liquid is sent to a supply path (16a) (not shown).

  As shown in Table 1, the example 1 having the predetermined main flow path and the sub flow path has a higher pressure than the comparative example 1 having no main flow path (notch groove). It can be seen that the mixing efficiency is maintained and improved while reducing the loss. In addition, since the measurement result of the light absorbency in the comparative example 1 does not contact both liquids to the inside of the discharge path (21) provided in the downstream of said round hole (3), in the discharge path (21) It is thought that the mixture of was influenced.

DESCRIPTION OF SYMBOLS 1 Micromixer 2 Main body part 3 Round hole 4 Shaft body 5 Inner peripheral surface 6 Outer surface 7a, 7b Main flow path 8a-g Subflow path 9a, 9b Notch groove 10 Concave groove 11 Mounting hole 12 Adapter 13 Male thread part 14 Opening part 15 Female thread portions 16a, 16b Supply passages 17a, 17b Supply holes 18a, 18b Male threads 20a, 20b Female screw portions 21 Discharge passage 22 Discharge holes 23 Connectors 24 Male screw portions 25 Female thread portions 26 A liquid storage tank 27 B liquid storage Tank 28 Pump 29 Orifice 30 Manometer (pressure gauge)
31 Storage tank for liquid mixture of liquid A and liquid B 32 Micromixer 33 Measurement system

Claims (4)

A flow in which a shaft body is inserted into an axially long round hole formed in the main body, and a plurality of fluids are mixed while flowing in the gap between the inner peripheral surface of the round hole and the outer surface of the shaft body. A micromixer that forms a path,
A plurality of main flow paths extending parallel to each other along the axial direction;
A plurality of sub-channels extending in an oblique direction with respect to the axial direction and communicating between the main channels;
A micromixer characterized in that the plurality of types of fluids are mixed by repeatedly branching / merging the fluid in another main channel through the sub-channel with the fluid flowing in the main channel.   The plurality of main flow paths are formed of a plurality of parallel cutout grooves formed on the outer surface of the shaft body at intervals in the circumferential direction, and the sub flow paths are also formed on the outer surface of the shaft body. The micromixer according to claim 1, wherein the micromixer is formed of a single or a plurality of concave grooves that are formed and extend spirally while intersecting the notch grooves.   A mounting hole for mounting the shaft body is provided in the main body portion so as to communicate with the upstream axial direction of the round hole, and is opened at a position corresponding to the upstream portion of each main flow path of the round hole. The micromixer according to claim 1, wherein a plurality of supply paths for supplying fluid to the path are provided. A microreactor comprising the micromixer according to claim 1.

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