JP2012531954A5 - - Google Patents

Info

Publication number

JP2012531954A5

JP2012531954A5 JP2012517893A JP2012517893A JP2012531954A5 JP 2012531954 A5 JP2012531954 A5 JP 2012531954A5 JP 2012517893 A JP2012517893 A JP 2012517893A JP 2012517893 A JP2012517893 A JP 2012517893A JP 2012531954 A5 JP2012531954 A5 JP 2012531954A5

Authority

JP

Japan

Prior art keywords

aldehyde

daltons

average molecular

molecular weight

water

Prior art date

2010-06-30

Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)

Granted

Links

• Espacenet
• Global Dossier
• Discuss

• 125000003172 aldehyde group Chemical group 0.000 claims description 25
• 150000001412 amines Chemical class 0.000 claims description 25
• 150000004676 glycans Chemical class 0.000 claims description 20
• 229920001282 polysaccharide Polymers 0.000 claims description 20
• 239000005017 polysaccharide Substances 0.000 claims description 20
• 125000002924 primary amino group Chemical group [H]N([H])* 0.000 claims description 17
• 239000000017 hydrogel Substances 0.000 claims description 14
• 125000002485 formyl group Chemical class [H]C(*)=O 0.000 claims description 12
• 239000000203 mixture Substances 0.000 claims description 11
• 238000006467 substitution reaction Methods 0.000 claims description 10
• 238000000034 method Methods 0.000 claims description 8
• 239000006185 dispersion Substances 0.000 claims description 7
• XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 claims description 6
• 125000003277 amino group Chemical group 0.000 claims description 4
• 239000002904 solvent Substances 0.000 claims description 4
• 210000003484 anatomy Anatomy 0.000 claims description 2
• 239000007795 chemical reaction product Substances 0.000 claims description 2
• 239000011248 coating agent Substances 0.000 claims description 2
• 238000000576 coating method Methods 0.000 claims description 2
• 229920002307 Dextran Polymers 0.000 description 8
• 239000007864 aqueous solution Substances 0.000 description 6
• 229920001451 polypropylene glycol Polymers 0.000 description 6
• 239000004721 Polyphenylene oxide Substances 0.000 description 5
• 229920000570 polyether Polymers 0.000 description 5
• 229920001202 Inulin Polymers 0.000 description 4
• JYJIGFIDKWBXDU-MNNPPOADSA-N inulin Chemical compound O[C@H]1[C@H](O)[C@@H](CO)O[C@@]1(CO)OC[C@]1(OC[C@]2(OC[C@]3(OC[C@]4(OC[C@]5(OC[C@]6(OC[C@]7(OC[C@]8(OC[C@]9(OC[C@]%10(OC[C@]%11(OC[C@]%12(OC[C@]%13(OC[C@]%14(OC[C@]%15(OC[C@]%16(OC[C@]%17(OC[C@]%18(OC[C@]%19(OC[C@]%20(OC[C@]%21(OC[C@]%22(OC[C@]%23(OC[C@]%24(OC[C@]%25(OC[C@]%26(OC[C@]%27(OC[C@]%28(OC[C@]%29(OC[C@]%30(OC[C@]%31(OC[C@]%32(OC[C@]%33(OC[C@]%34(OC[C@]%35(OC[C@]%36(O[C@@H]%37[C@@H]([C@@H](O)[C@H](O)[C@@H](CO)O%37)O)[C@H]([C@H](O)[C@@H](CO)O%36)O)[C@H]([C@H](O)[C@@H](CO)O%35)O)[C@H]([C@H](O)[C@@H](CO)O%34)O)[C@H]([C@H](O)[C@@H](CO)O%33)O)[C@H]([C@H](O)[C@@H](CO)O%32)O)[C@H]([C@H](O)[C@@H](CO)O%31)O)[C@H]([C@H](O)[C@@H](CO)O%30)O)[C@H]([C@H](O)[C@@H](CO)O%29)O)[C@H]([C@H](O)[C@@H](CO)O%28)O)[C@H]([C@H](O)[C@@H](CO)O%27)O)[C@H]([C@H](O)[C@@H](CO)O%26)O)[C@H]([C@H](O)[C@@H](CO)O%25)O)[C@H]([C@H](O)[C@@H](CO)O%24)O)[C@H]([C@H](O)[C@@H](CO)O%23)O)[C@H]([C@H](O)[C@@H](CO)O%22)O)[C@H]([C@H](O)[C@@H](CO)O%21)O)[C@H]([C@H](O)[C@@H](CO)O%20)O)[C@H]([C@H](O)[C@@H](CO)O%19)O)[C@H]([C@H](O)[C@@H](CO)O%18)O)[C@H]([C@H](O)[C@@H](CO)O%17)O)[C@H]([C@H](O)[C@@H](CO)O%16)O)[C@H]([C@H](O)[C@@H](CO)O%15)O)[C@H]([C@H](O)[C@@H](CO)O%14)O)[C@H]([C@H](O)[C@@H](CO)O%13)O)[C@H]([C@H](O)[C@@H](CO)O%12)O)[C@H]([C@H](O)[C@@H](CO)O%11)O)[C@H]([C@H](O)[C@@H](CO)O%10)O)[C@H]([C@H](O)[C@@H](CO)O9)O)[C@H]([C@H](O)[C@@H](CO)O8)O)[C@H]([C@H](O)[C@@H](CO)O7)O)[C@H]([C@H](O)[C@@H](CO)O6)O)[C@H]([C@H](O)[C@@H](CO)O5)O)[C@H]([C@H](O)[C@@H](CO)O4)O)[C@H]([C@H](O)[C@@H](CO)O3)O)[C@H]([C@H](O)[C@@H](CO)O2)O)[C@@H](O)[C@H](O)[C@@H](CO)O1 JYJIGFIDKWBXDU-MNNPPOADSA-N 0.000 description 4
• 229940029339 inulin Drugs 0.000 description 4
• 239000000243 solution Substances 0.000 description 4
• KIUKXJAPPMFGSW-DNGZLQJQSA-N (2S,3S,4S,5R,6R)-6-[(2S,3R,4R,5S,6R)-3-Acetamido-2-[(2S,3S,4R,5R,6R)-6-[(2R,3R,4R,5S,6R)-3-acetamido-2,5-dihydroxy-6-(hydroxymethyl)oxan-4-yl]oxy-2-carboxy-4,5-dihydroxyoxan-3-yl]oxy-5-hydroxy-6-(hydroxymethyl)oxan-4-yl]oxy-3,4,5-trihydroxyoxane-2-carboxylic acid Chemical class CC(=O)N[C@H]1[C@H](O)O[C@H](CO)[C@@H](O)[C@@H]1O[C@H]1[C@H](O)[C@@H](O)[C@H](O[C@H]2[C@@H]([C@@H](O[C@H]3[C@@H]([C@@H](O)[C@H](O)[C@H](O3)C(O)=O)O)[C@H](O)[C@@H](CO)O2)NC(C)=O)[C@@H](C(O)=O)O1 KIUKXJAPPMFGSW-DNGZLQJQSA-N 0.000 description 3
• 229920001817 Agar Polymers 0.000 description 3
• 229920002134 Carboxymethyl cellulose Polymers 0.000 description 3
• 229920000663 Hydroxyethyl cellulose Polymers 0.000 description 3
• 239000004354 Hydroxyethyl cellulose Substances 0.000 description 3
• 229920003171 Poly (ethylene oxide) Polymers 0.000 description 3
• 239000004698 Polyethylene Substances 0.000 description 3
• 229920001218 Pullulan Polymers 0.000 description 3
• 239000004373 Pullulan Substances 0.000 description 3
• 229920002472 Starch Polymers 0.000 description 3
• 239000008272 agar Substances 0.000 description 3
• 235000010419 agar Nutrition 0.000 description 3
• 239000001768 carboxy methyl cellulose Substances 0.000 description 3
• 235000010948 carboxy methyl cellulose Nutrition 0.000 description 3
• 239000008112 carboxymethyl-cellulose Substances 0.000 description 3
• 229920002678 cellulose Polymers 0.000 description 3
• 239000001913 cellulose Substances 0.000 description 3
• 235000010980 cellulose Nutrition 0.000 description 3
• 235000019447 hydroxyethyl cellulose Nutrition 0.000 description 3
• AIHDCSAXVMAMJH-GFBKWZILSA-N levan Chemical compound O[C@H]1[C@H](O)[C@@H](CO)O[C@@]1(CO)OC[C@@H]1[C@@H](O)[C@H](O)[C@](CO)(CO[C@@H]2[C@H]([C@H](O)[C@@](O)(CO)O2)O)O1 AIHDCSAXVMAMJH-GFBKWZILSA-N 0.000 description 3
• 229920000962 poly(amidoamine) Polymers 0.000 description 3
• -1 polyethylene Polymers 0.000 description 3
• 229920000573 polyethylene Polymers 0.000 description 3
• 235000019423 pullulan Nutrition 0.000 description 3
• 239000008107 starch Substances 0.000 description 3
• 235000019698 starch Nutrition 0.000 description 3
• 239000000499 gel Substances 0.000 description 1
• 239000012528 membrane Substances 0.000 description 1
• 239000012265 solid product Substances 0.000 description 1