JP2012530057A5 - - Google Patents
Download PDFInfo
- Publication number
- JP2012530057A5 JP2012530057A5 JP2012515147A JP2012515147A JP2012530057A5 JP 2012530057 A5 JP2012530057 A5 JP 2012530057A5 JP 2012515147 A JP2012515147 A JP 2012515147A JP 2012515147 A JP2012515147 A JP 2012515147A JP 2012530057 A5 JP2012530057 A5 JP 2012530057A5
- Authority
- JP
- Japan
- Prior art keywords
- agent
- drug
- peptide
- administered
- medicament
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US18598909P | 2009-06-10 | 2009-06-10 | |
| US61/185,989 | 2009-06-10 | ||
| PCT/US2010/038200 WO2010144721A2 (en) | 2009-06-10 | 2010-06-10 | Model systems and treatment regimes for treatment of neurological disease |
Related Child Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2015214926A Division JP6220371B2 (ja) | 2009-06-10 | 2015-10-30 | 神経疾患の治療のためのモデル系及び治療計画 |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2012530057A JP2012530057A (ja) | 2012-11-29 |
| JP2012530057A5 true JP2012530057A5 (https=) | 2013-07-04 |
| JP6005514B2 JP6005514B2 (ja) | 2016-10-12 |
Family
ID=43309469
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2012515147A Expired - Fee Related JP6005514B2 (ja) | 2009-06-10 | 2010-06-10 | 神経疾患の治療のためのモデル系及び治療計画 |
| JP2015214926A Expired - Fee Related JP6220371B2 (ja) | 2009-06-10 | 2015-10-30 | 神経疾患の治療のためのモデル系及び治療計画 |
Family Applications After (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2015214926A Expired - Fee Related JP6220371B2 (ja) | 2009-06-10 | 2015-10-30 | 神経疾患の治療のためのモデル系及び治療計画 |
Country Status (14)
| Country | Link |
|---|---|
| US (2) | US8940699B2 (https=) |
| EP (2) | EP2440230B1 (https=) |
| JP (2) | JP6005514B2 (https=) |
| CN (1) | CN102458441A (https=) |
| AU (1) | AU2010258664B2 (https=) |
| BR (1) | BRPI1010718A2 (https=) |
| CA (1) | CA2765169C (https=) |
| DK (1) | DK2440230T3 (https=) |
| ES (1) | ES2847293T3 (https=) |
| HR (1) | HRP20210112T1 (https=) |
| HU (1) | HUE053131T2 (https=) |
| PL (1) | PL2440230T3 (https=) |
| PT (1) | PT2440230T (https=) |
| WO (1) | WO2010144721A2 (https=) |
Families Citing this family (21)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US7510824B2 (en) * | 1999-06-02 | 2009-03-31 | Nono Inc. | Method of screening peptides useful in treating traumatic injury to the brain or spinal cord |
| WO2010144721A2 (en) | 2009-06-10 | 2010-12-16 | Arbor Vita Corporation | Model systems and treatment regimes for treatment of neurological disease |
| EP2616094B1 (en) | 2010-08-12 | 2017-11-08 | NoNO Inc. | Treatment of penetrative injury to the brain |
| ES2912042T3 (es) | 2011-06-24 | 2022-05-24 | Nono Inc | Terapia de combinación para isquemia |
| MX364562B (es) * | 2011-12-13 | 2019-04-30 | Nono Inc | Terapia para hemorragia subaracnoidea e isquemia. |
| US9241970B2 (en) | 2011-12-13 | 2016-01-26 | Nono Inc. | Therapy for subarachnoid hemorrhage and ischemia |
| AU2013204309A1 (en) * | 2012-11-13 | 2014-05-29 | Biodiem Limited | Therapeutic Compounds and Uses Thereof |
| US10251935B2 (en) | 2012-11-28 | 2019-04-09 | Nono Inc. | Lyophilized formulation comprising tat-NR2B9C, histidine and trehalose |
| CA2892965C (en) * | 2012-11-28 | 2021-06-01 | Nono Inc. | Lyophilized formulation of tat-nr2b9c |
| WO2015181756A1 (en) | 2014-05-28 | 2015-12-03 | Nono Inc. | Chloride salt of tat-nr2b9c |
| KR102253900B1 (ko) * | 2016-04-27 | 2021-05-18 | 바이오셀즈(베이징) 바이오테크 코., 엘티디. | 흥분성 신경독성 관련 손상 치료용 펩타이드 |
| EP3450446A1 (en) * | 2016-04-27 | 2019-03-06 | Biocells (Beijing) Biotech Co., Ltd. | Treatment method for excitatory neurotoxicity-related injury |
| CN110049994B (zh) * | 2016-12-08 | 2023-05-02 | 拜西欧斯（北京）生物技术有限公司 | 一种缀合物及其应用 |
| WO2019006692A1 (zh) * | 2017-07-05 | 2019-01-10 | 拜西欧斯（北京）生物技术有限公司 | 用于治疗、改善或预防神经系统相关病症的化合物及其用途 |
| KR102403089B1 (ko) * | 2017-07-05 | 2022-06-02 | 바이오셀즈(베이징) 바이오테크 코., 엘티디. | 폴리펩타이드의 약학적으로 허용 가능한 염 및 이의 용도 |
| KR102545825B1 (ko) | 2017-09-30 | 2023-06-22 | 바이오셀즈(베이징) 바이오테크 코., 엘티디. | 흥분성 신경 독성 관련 손상 치료를 위한 펩타이드 조성물 |
| CN113121641B (zh) | 2021-03-11 | 2022-11-01 | 武汉英纳氏药业有限公司 | 一类多功能多肽及其在医药领域的应用 |
| CN113150065B (zh) | 2021-03-11 | 2022-07-08 | 武汉英纳氏药业有限公司 | 一种合成肽及其应用 |
| CN113735938B (zh) | 2021-07-30 | 2024-11-08 | 英纳氏(珠海)药业有限公司 | 一种神经保护多肽化合物及其应用 |
| CN114642402A (zh) * | 2022-03-07 | 2022-06-21 | 翰博瑞强(上海)医药科技有限公司 | 一种用于预测药物对心脏毒性影响的方法及心电图设备 |
| CN114469084B (zh) * | 2022-04-02 | 2022-06-24 | 剑博微电子(深圳)有限公司 | 一种基于高精度adc的血氧监测系统 |
Family Cites Families (16)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US20060148711A1 (en) | 1999-05-14 | 2006-07-06 | Arbor Vita Corporation | Molecular interactions in neurons |
| US7510824B2 (en) | 1999-06-02 | 2009-03-31 | Nono Inc. | Method of screening peptides useful in treating traumatic injury to the brain or spinal cord |
| GB0025473D0 (en) | 2000-10-17 | 2000-11-29 | Pfizer Ltd | Pharmaceutical combinations |
| WO2004045535A2 (en) * | 2002-11-14 | 2004-06-03 | Arbor Vita Corporation | Molecular interactions in neurons |
| EP1601380A1 (en) | 2003-02-13 | 2005-12-07 | Licentia OY | Use of a mast cell activation or degranulation blocking agent in the manufacture of a medicament for the treatment of cerebral ischemia |
| CA2524573A1 (en) | 2003-05-02 | 2004-11-11 | Paion Deutschland Gmbh | Intravenous injection of non-neurotoxic plasminogen activators for the treatment of stroke |
| DK2043671T3 (da) * | 2006-07-11 | 2020-06-15 | Nono Inc | Peptid og sammensætning deraf til anvendelse ved behandling af slagtilfælde med feber |
| EP1884521A1 (en) * | 2006-07-31 | 2008-02-06 | Xigen S.A. | Fusion peptide for inhibiting interaction of neuronal NMDA receptor (NMDAR) and NMDAR interacting proteins |
| ES2446292T3 (es) * | 2007-03-02 | 2014-03-07 | Nono Inc. | Tratamiento del accidente cerebrovascular y otras enfermedades sin inhibir los canales de calcio de tipo N |
| WO2009006611A1 (en) | 2007-07-03 | 2009-01-08 | Arbor Vita Corporation | Small molecule inhibitors of pdz interactions |
| US8080518B2 (en) | 2007-12-05 | 2011-12-20 | Arbor Vita Corporation | Co-administration of an agent linked to an internalization peptide with an anti-inflammatory |
| DK2320927T3 (en) | 2008-07-09 | 2015-09-14 | Univ Copenhagen | Modified peptides as potent inhibitors of the PSD-95 / NMDA receptor interaction |
| WO2010144721A2 (en) | 2009-06-10 | 2010-12-16 | Arbor Vita Corporation | Model systems and treatment regimes for treatment of neurological disease |
| ES2912042T3 (es) | 2011-06-24 | 2022-05-24 | Nono Inc | Terapia de combinación para isquemia |
| US9241970B2 (en) | 2011-12-13 | 2016-01-26 | Nono Inc. | Therapy for subarachnoid hemorrhage and ischemia |
| MX364562B (es) | 2011-12-13 | 2019-04-30 | Nono Inc | Terapia para hemorragia subaracnoidea e isquemia. |
-
2010
- 2010-06-10 WO PCT/US2010/038200 patent/WO2010144721A2/en not_active Ceased
- 2010-06-10 ES ES10786859T patent/ES2847293T3/es active Active
- 2010-06-10 EP EP10786859.8A patent/EP2440230B1/en active Active
- 2010-06-10 AU AU2010258664A patent/AU2010258664B2/en not_active Ceased
- 2010-06-10 BR BRPI1010718A patent/BRPI1010718A2/pt not_active Application Discontinuation
- 2010-06-10 DK DK10786859.8T patent/DK2440230T3/da active
- 2010-06-10 HR HRP20210112TT patent/HRP20210112T1/hr unknown
- 2010-06-10 CA CA2765169A patent/CA2765169C/en active Active
- 2010-06-10 PL PL10786859T patent/PL2440230T3/pl unknown
- 2010-06-10 JP JP2012515147A patent/JP6005514B2/ja not_active Expired - Fee Related
- 2010-06-10 HU HUE10786859A patent/HUE053131T2/hu unknown
- 2010-06-10 EP EP20200385.1A patent/EP3808366A1/en not_active Withdrawn
- 2010-06-10 US US13/377,523 patent/US8940699B2/en active Active
- 2010-06-10 CN CN2010800352462A patent/CN102458441A/zh active Pending
- 2010-06-10 PT PT107868598T patent/PT2440230T/pt unknown
-
2015
- 2015-01-14 US US14/597,166 patent/US9610323B2/en not_active Expired - Fee Related
- 2015-10-30 JP JP2015214926A patent/JP6220371B2/ja not_active Expired - Fee Related
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| JP2012530057A5 (https=) | ||
| HRP20210112T1 (hr) | Režimi liječenja namijenjeni liječenju neurološke bolesti | |
| JP7085457B2 (ja) | 虚血のための組み合わせ療法 | |
| US11737810B2 (en) | Immunotherapeutic methods using electroporation | |
| Prunier et al. | Single high-dose erythropoietin administration immediately after reperfusion in patients with ST-segment elevation myocardial infarction: results of the erythropoietin in myocardial infarction trial | |
| Glushakov et al. | Animal models of posttraumatic seizures and epilepsy | |
| Gigliucci et al. | Characterisation of the antidepressant properties of nitric oxide synthase inhibitors in the olfactory bulbectomised rat model of depression | |
| CA2951686C (en) | The use of dextran sulfate having an average molecular weight below 10000 da for inducing angiogenesis in a subject | |
| AU2021206472A1 (en) | Plasmin-resistant peptides for treating stroke and related conditions | |
| Chaparro-Cabanillas et al. | Transient middle cerebral artery occlusion model of stroke | |
| Wu et al. | Combined VEGF and bFGF loaded nanofiber membrane protects against neuronal injury and hypomyelination in a rat model of chronic cerebral hypoperfusion | |
| Boulos et al. | Tamoxifen as an effective neuroprotectant in an endovascular canine model of stroke | |
| Wróbel et al. | The influence of nebivolol on the activity of BRL 37344—the β3‐adrenergic receptor agonist, in the animal model of detrusor overactivity | |
| WO2015190989A1 (en) | The use of dextran sulfate having an average molecular weight below 10000 da for inducing angiogenisis in a subject | |
| Choovongkomol et al. | Effect of a Single-dose Dexmedetomidine on Postoperative Delirium and Intraoperative Hemodynamic Outcomes in Elderly Hip Surgery; A Randomized Controlled Trial Dexmedetomidine for Postoperative Delirium: Dexmedetomidine for Postoperative Delirium | |
| Vichaya et al. | Spinal glia modulate both adaptive and pathological processes | |
| JP6351639B2 (ja) | リンパ節検出のための低浸透圧溶液 | |
| Tamura et al. | Endovascular embolization of brain arteriovenous malformations with Eudragit-E | |
| Gupta et al. | Comparative pre-emptive analgesic efficacy study of novel antiepileptic agents lamotrigine and topiramate in patients undergoing major surgeries at a tertiary care hospital: a randomized double blind clinical trial | |
| Zheng et al. | The novel PSD-95 inhibitor BXOS110 provides neuroprotection in acute ischemic stroke | |
| Abou Shokka et al. | Retrograde transcatheter closure of perimembranous aneurysmal ventricular septal defects using amplatzer vascular plug II. | |
| Shabani et al. | Does coronary microvascular dysfunction play a role in heart failure with reduced ejection fraction? | |
| Rajendran et al. | Hypertension: Interventional Options | |
| Xiao-jun | Endovascular embolic treatment of ruptured vertebral artery dissecting aneurysms | |
| Nakayama et al. | Endovascular trapping for a giant aneurysm of the cervical internal carotid artery: a case report |