JP2012524521A - グリコデリンモノクローナル抗体および卵巣癌の検出におけるその使用のための方法 - Google Patents

グリコデリンモノクローナル抗体および卵巣癌の検出におけるその使用のための方法 Download PDF

Info

Publication number
JP2012524521A
JP2012524521A JP2011553128A JP2011553128A JP2012524521A JP 2012524521 A JP2012524521 A JP 2012524521A JP 2011553128 A JP2011553128 A JP 2011553128A JP 2011553128 A JP2011553128 A JP 2011553128A JP 2012524521 A JP2012524521 A JP 2012524521A
Authority
JP
Japan
Prior art keywords
monoclonal antibody
seq
glycodelin
ovarian cancer
antibody
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
JP2011553128A
Other languages
English (en)
Japanese (ja)
Other versions
JP2012524521A5 (https=
Inventor
チーク，ロバート・エル
ディクソン，エリック・ピー
フィッシャー，ティモシー・ジェイ
グレルキー，ジョン・ダブリュー
ナップ，スティーヴン・エル
シムキンズ，スティーヴン・ジー
ホワイトヘッド，クラーク・エム
Original Assignee
トライパス イメージング インコーポレイテッド
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by トライパス イメージング インコーポレイテッド filed Critical トライパス イメージング インコーポレイテッド
Publication of JP2012524521A publication Critical patent/JP2012524521A/ja
Publication of JP2012524521A5 publication Critical patent/JP2012524521A5/ja
Pending legal-status Critical Current

Links

Images

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies
    • C07K16/18—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/28—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
    • C07K16/30—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants from tumour cells
    • C07K16/3069—Reproductive system, e.g. ovaria, uterus, testes, prostate
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies
    • C07K16/18—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/575—Immunoassay; Biospecific binding assay; Materials therefor for cancer
    • G01N33/57545—Immunoassay; Biospecific binding assay; Materials therefor for cancer of the ovaries
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/30—Immunoglobulins specific features characterized by aspects of specificity or valency
    • C07K2317/34—Identification of a linear epitope shorter than 20 amino acid residues or of a conformational epitope defined by amino acid residues

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Immunology (AREA)
  • Organic Chemistry (AREA)
  • Molecular Biology (AREA)
  • Engineering & Computer Science (AREA)
  • Biochemistry (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Urology & Nephrology (AREA)
  • Genetics & Genomics (AREA)
  • Hematology (AREA)
  • Cell Biology (AREA)
  • Biophysics (AREA)
  • Biomedical Technology (AREA)
  • Physics & Mathematics (AREA)
  • General Physics & Mathematics (AREA)
  • Pathology (AREA)
  • Gynecology & Obstetrics (AREA)
  • Pregnancy & Childbirth (AREA)
  • Reproductive Health (AREA)
  • Analytical Chemistry (AREA)
  • Food Science & Technology (AREA)
  • Microbiology (AREA)
  • Biotechnology (AREA)
  • Peptides Or Proteins (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
JP2011553128A 2009-03-06 2010-03-05 グリコデリンモノクローナル抗体および卵巣癌の検出におけるその使用のための方法 Pending JP2012524521A (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US15815909P 2009-03-06 2009-03-06
US61/158,159 2009-03-06
PCT/US2010/026319 WO2010102177A1 (en) 2009-03-06 2010-03-05 Glycodelin monoclonal antibodies and methods for their use in the detection of ovarian cancer

Publications (2)

Publication Number Publication Date
JP2012524521A true JP2012524521A (ja) 2012-10-18
JP2012524521A5 JP2012524521A5 (https=) 2013-04-18

Family

ID=42101610

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2011553128A Pending JP2012524521A (ja) 2009-03-06 2010-03-05 グリコデリンモノクローナル抗体および卵巣癌の検出におけるその使用のための方法

Country Status (6)

Country Link
US (2) US8252904B2 (https=)
EP (1) EP2403875A1 (https=)
JP (1) JP2012524521A (https=)
AU (1) AU2010221188A1 (https=)
CA (1) CA2753713A1 (https=)
WO (1) WO2010102177A1 (https=)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2022060333A (ja) * 2017-12-05 2022-04-14 国立大学法人金沢大学 膠芽腫マーカー及びその使用

Families Citing this family (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20140295426A1 (en) * 2011-07-28 2014-10-02 Veridex Llc Methods for Diagnosing Cancer by Characterization of Tumor Cells Associated with Pleural or Serous Fluids
JP6120848B2 (ja) 2011-08-15 2017-04-26 メディミューン，エルエルシー 抗ｂ７−ｈ４抗体およびその使用
AU2013361275B2 (en) 2012-12-19 2016-11-24 Amplimmune, Inc. Anti-human B7-H4 antibodies and their uses
GB201520568D0 (en) 2015-11-23 2016-01-06 Immunocore Ltd Peptides
GB201520550D0 (en) 2015-11-23 2016-01-06 Immunocore Ltd & Adaptimmune Ltd Peptides
GB201604468D0 (en) * 2016-03-16 2016-04-27 Immunocore Ltd & Adaptimmune Ltd Peptides
CN106199012A (zh) * 2016-06-30 2016-12-07 深圳市亚辉龙生物科技股份有限公司 抑制素b化学发光免疫检测试剂盒及其制备方法
CN106053836A (zh) * 2016-06-30 2016-10-26 深圳市亚辉龙生物科技股份有限公司 抗子宫内膜抗体化学发光免疫检测试剂盒及其制备方法
US20190346457A1 (en) 2018-03-13 2019-11-14 Government Of The Unted States, As Represented By The Secretary Of The Army Assays and methods for detection and targeted treatment of hydrosalpinx
MY204234A (en) 2018-08-27 2024-08-16 Regeneron Pharma Use of raman spectroscopy in downstream purification
CN116496394B (zh) * 2022-01-26 2024-07-23 东莞市朋志生物科技有限公司 抗s100蛋白的抗体、检测s100蛋白的试剂和试剂盒

Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2002045657A2 (en) * 2000-12-08 2002-06-13 Corixa Corporation Ovarian tumor antigen and methods of use therefor
WO2007090076A2 (en) * 2006-01-27 2007-08-09 Tripath Imaging, Inc. Methods for identifying patients with an increased likelihood of having ovarian cancer and compositions therefor

Family Cites Families (26)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
NZ201918A (en) 1981-09-18 1987-04-30 Genentech Inc N-terminal methionyl analogues of bovine growth hormone
US4708871A (en) 1983-03-08 1987-11-24 Commonwealth Serum Laboratories Commission Antigenically active amino acid sequences
US4816567A (en) 1983-04-08 1989-03-28 Genentech, Inc. Recombinant immunoglobin preparations
US5260203A (en) 1986-09-02 1993-11-09 Enzon, Inc. Single polypeptide chain binding molecules
US4946778A (en) 1987-09-21 1990-08-07 Genex Corporation Single polypeptide chain binding molecules
US4873192A (en) 1987-02-17 1989-10-10 The United States Of America As Represented By The Department Of Health And Human Services Process for site specific mutagenesis without phenotypic selection
EP0436597B1 (en) 1988-09-02 1997-04-02 Protein Engineering Corporation Generation and selection of recombinant varied binding proteins
US5223409A (en) 1988-09-02 1993-06-29 Protein Engineering Corp. Directed evolution of novel binding proteins
US5427908A (en) 1990-05-01 1995-06-27 Affymax Technologies N.V. Recombinant library screening methods
EP0585287B1 (en) 1990-07-10 1999-10-13 Cambridge Antibody Technology Limited Methods for producing members of specific binding pairs
GB9015198D0 (en) 1990-07-10 1990-08-29 Brien Caroline J O Binding substance
GB9022543D0 (en) 1990-10-17 1990-11-28 Wellcome Found Antibody production
CA2405246A1 (en) 1990-12-03 1992-06-11 Genentech, Inc. Enrichment method for variant proteins with alterred binding properties
EP0575485A1 (en) 1991-03-01 1993-12-29 Dyax Corp. Process for the development of binding mini-proteins
DK0580737T3 (da) 1991-04-10 2004-11-01 Scripps Research Inst Heterodimere receptorbiblioteker ved anvendelse af phagemider
CA2064544A1 (en) 1991-06-28 1992-12-29 Anthony E. Bolton Immune cell proliferation inhibitors
DE4122599C2 (de) 1991-07-08 1993-11-11 Deutsches Krebsforsch Phagemid zum Screenen von Antikörpern
WO1994012520A1 (en) 1992-11-20 1994-06-09 Enzon, Inc. Linker for linked fusion polypeptides
DE614989T1 (de) 1993-02-17 1995-09-28 Morphosys Proteinoptimierung Verfahren für in vivo Selektion von Ligandenbindende Proteine.
US5830698A (en) 1997-03-14 1998-11-03 Idec Pharmaceuticals Corporation Method for integrating genes at specific sites in mammalian cells via homologous recombination and vectors for accomplishing the same
DE19807389C2 (de) 1998-02-21 2000-08-17 Max Delbrueck Centrum Monoklonale Antikörper gegen Glycodelin A, Verfahren zu ihrer Herstellung und ihre Verwendung
AU2002258518A1 (en) * 2001-03-14 2002-09-24 Millennium Pharmaceuticals, Inc. Nucleic acid molecules and proteins for the identification, assessment, prevention, and therapy of ovarian cancer
ATE549625T1 (de) 2004-03-24 2012-03-15 Tripath Imaging Inc Verfahren und zusammensetzungen zum nachweis einer zervixerkrankung
US7595380B2 (en) 2005-04-27 2009-09-29 Tripath Imaging, Inc. Monoclonal antibodies and methods for their use in the detection of cervical disease
CN101802014A (zh) 2007-03-09 2010-08-11 三路影像公司 He4单克隆抗体和它们的使用方法
WO2009032974A2 (en) 2007-09-06 2009-03-12 Tripath Imaging, Inc. Nucleic acid-based methods for the detection of ovarian cancer

Patent Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2002045657A2 (en) * 2000-12-08 2002-06-13 Corixa Corporation Ovarian tumor antigen and methods of use therefor
WO2007090076A2 (en) * 2006-01-27 2007-08-09 Tripath Imaging, Inc. Methods for identifying patients with an increased likelihood of having ovarian cancer and compositions therefor

Non-Patent Citations (4)

* Cited by examiner, † Cited by third party
Title
JPN6014031507; Ｊｏｕｒｎａｌ　ｏｆ　Ｉｍｍｕｎｏｌｏｇｉｃａｌ　Ｍｅｔｈｏｄｓ Ｖｏｌ．１３６, 1991, ｐ．８５-９０ *
JPN6014031508; Ｔｈｅ　Ｈｉｓｔｏｃｈｅｍｉｃａｌ　Ｊｏｕｒｎａｌ Ｖｏｌ．３２, 2000, ｐ．７１１-７１６ *
JPN6014031509; Ｈｉｓｔｏｐａｔｈｏｌｏｇｙ Ｖｏｌ．４８, 2006, ｐ．３９４-４０６ *
JPN6014031510; ＡＮＴＩＣＡＮＣＥＲ　ＲＥＳＥＡＲＣＨ Ｖｏｌ．２５, 2005, ｐ．１６３９-１６４４ *

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2022060333A (ja) * 2017-12-05 2022-04-14 国立大学法人金沢大学 膠芽腫マーカー及びその使用
JP7211604B2 (ja) 2017-12-05 2023-01-24 国立大学法人金沢大学 膠芽腫マーカー及びその使用

Also Published As

Publication number Publication date
WO2010102177A1 (en) 2010-09-10
US20100227343A1 (en) 2010-09-09
CA2753713A1 (en) 2010-09-10
US8476033B2 (en) 2013-07-02
AU2010221188A1 (en) 2011-10-20
US20130022998A1 (en) 2013-01-24
US8252904B2 (en) 2012-08-28
EP2403875A1 (en) 2012-01-11

Similar Documents

Publication Publication Date Title
US8252904B2 (en) Glycodelin monoclonal antibodies and methods for their use in the detection of ovarian cancer
US20100227335A1 (en) Matrix metalloproteinase-7 (mmp-7) monoclonal antibodies and methods for their use in the detection of ovarian cancer
US7846692B2 (en) HE4 monoclonal antibodies and methods for their use
JP6554152B2 (ja) 葉酸受容体アルファ発現癌の診断および予後マーカーとしての葉酸受容体アルファ
CA2809368C (en) Methods for detecting anti-he4 antibodies and methods of diagnosis and/or prognosis of conditions associated with he4-expressing cells
CN114705858A (zh) 用于评估癌症发生的风险的组合物和方法
CN103429617B (zh) 包含抗-ck8/18复合物自身抗体的标记物及其诊断癌症的用途
CN103732627A (zh) 包含抗-atic自身免疫抗体的肝癌诊断标记物以及包含其抗原的肝癌诊断用组合物
AU2015215008B2 (en) Composition and method for detecting malignant neoplastic disease
CN111303289B (zh) 抗人Tn型糖基化MUC1抗体及其用途
JP6729917B2 (ja) ＥｐｈＡ２ Ｎ末端フラグメント抗体
HK40073614A (en) Compositions and methods for assessing the risk of cancer occurrence
HK1262633A1 (en) Compositions and methods for assessing the risk of cancer occurrence
HK1262633B (zh) 用於评估癌症发生的风险的组合物和方法

Legal Events

Date Code Title Description
A521 Request for written amendment filed

Free format text: JAPANESE INTERMEDIATE CODE: A523

Effective date: 20130304

A621 Written request for application examination

Free format text: JAPANESE INTERMEDIATE CODE: A621

Effective date: 20130304

A131 Notification of reasons for refusal

Free format text: JAPANESE INTERMEDIATE CODE: A131

Effective date: 20140729

A02 Decision of refusal

Free format text: JAPANESE INTERMEDIATE CODE: A02

Effective date: 20150317