CA2753713A1 - Glycodelin monoclonal antibodies and methods for their use in the detection of ovarian cancer - Google Patents

Glycodelin monoclonal antibodies and methods for their use in the detection of ovarian cancer Download PDF

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Publication number
CA2753713A1
CA2753713A1 CA2753713A CA2753713A CA2753713A1 CA 2753713 A1 CA2753713 A1 CA 2753713A1 CA 2753713 A CA2753713 A CA 2753713A CA 2753713 A CA2753713 A CA 2753713A CA 2753713 A1 CA2753713 A1 CA 2753713A1
Authority
CA
Canada
Prior art keywords
glycodelin
monoclonal antibody
seq
antibody
ovarian cancer
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Abandoned
Application number
CA2753713A
Other languages
English (en)
French (fr)
Inventor
Robert L. Cheek
Eric P. Dixon
Timothy J. Fischer
John W. Groelke
Steven L. Knapp
Stephen G. Simkins
Clark M. Whitehead
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
TriPath Imaging Inc
Original Assignee
TriPath Imaging Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by TriPath Imaging Inc filed Critical TriPath Imaging Inc
Publication of CA2753713A1 publication Critical patent/CA2753713A1/en
Abandoned legal-status Critical Current

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K16/00Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies
    • C07K16/18Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/28Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
    • C07K16/30Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants from tumour cells
    • C07K16/3069Reproductive system, e.g. ovaria, uterus, testes, prostate
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K16/00Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies
    • C07K16/18Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/575Immunoassay; Biospecific binding assay; Materials therefor for cancer
    • G01N33/57545Immunoassay; Biospecific binding assay; Materials therefor for cancer of the ovaries
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K2317/00Immunoglobulins specific features
    • C07K2317/30Immunoglobulins specific features characterized by aspects of specificity or valency
    • C07K2317/34Identification of a linear epitope shorter than 20 amino acid residues or of a conformational epitope defined by amino acid residues

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Immunology (AREA)
  • Organic Chemistry (AREA)
  • Molecular Biology (AREA)
  • Engineering & Computer Science (AREA)
  • Biochemistry (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Urology & Nephrology (AREA)
  • Genetics & Genomics (AREA)
  • Hematology (AREA)
  • Cell Biology (AREA)
  • Biophysics (AREA)
  • Biomedical Technology (AREA)
  • Physics & Mathematics (AREA)
  • General Physics & Mathematics (AREA)
  • Pathology (AREA)
  • Gynecology & Obstetrics (AREA)
  • Pregnancy & Childbirth (AREA)
  • Reproductive Health (AREA)
  • Analytical Chemistry (AREA)
  • Food Science & Technology (AREA)
  • Microbiology (AREA)
  • Biotechnology (AREA)
  • Peptides Or Proteins (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
CA2753713A 2009-03-06 2010-03-05 Glycodelin monoclonal antibodies and methods for their use in the detection of ovarian cancer Abandoned CA2753713A1 (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US15815909P 2009-03-06 2009-03-06
US61/158,159 2009-03-06
PCT/US2010/026319 WO2010102177A1 (en) 2009-03-06 2010-03-05 Glycodelin monoclonal antibodies and methods for their use in the detection of ovarian cancer

Publications (1)

Publication Number Publication Date
CA2753713A1 true CA2753713A1 (en) 2010-09-10

Family

ID=42101610

Family Applications (1)

Application Number Title Priority Date Filing Date
CA2753713A Abandoned CA2753713A1 (en) 2009-03-06 2010-03-05 Glycodelin monoclonal antibodies and methods for their use in the detection of ovarian cancer

Country Status (6)

Country Link
US (2) US8252904B2 (https=)
EP (1) EP2403875A1 (https=)
JP (1) JP2012524521A (https=)
AU (1) AU2010221188A1 (https=)
CA (1) CA2753713A1 (https=)
WO (1) WO2010102177A1 (https=)

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* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20140295426A1 (en) * 2011-07-28 2014-10-02 Veridex Llc Methods for Diagnosing Cancer by Characterization of Tumor Cells Associated with Pleural or Serous Fluids
JP6120848B2 (ja) 2011-08-15 2017-04-26 メディミューン,エルエルシー 抗b7−h4抗体およびその使用
AU2013361275B2 (en) 2012-12-19 2016-11-24 Amplimmune, Inc. Anti-human B7-H4 antibodies and their uses
GB201520568D0 (en) 2015-11-23 2016-01-06 Immunocore Ltd Peptides
GB201520550D0 (en) 2015-11-23 2016-01-06 Immunocore Ltd & Adaptimmune Ltd Peptides
GB201604468D0 (en) * 2016-03-16 2016-04-27 Immunocore Ltd & Adaptimmune Ltd Peptides
CN106199012A (zh) * 2016-06-30 2016-12-07 深圳市亚辉龙生物科技股份有限公司 抑制素b化学发光免疫检测试剂盒及其制备方法
CN106053836A (zh) * 2016-06-30 2016-10-26 深圳市亚辉龙生物科技股份有限公司 抗子宫内膜抗体化学发光免疫检测试剂盒及其制备方法
JP7211604B2 (ja) * 2017-12-05 2023-01-24 国立大学法人金沢大学 膠芽腫マーカー及びその使用
US20190346457A1 (en) 2018-03-13 2019-11-14 Government Of The Unted States, As Represented By The Secretary Of The Army Assays and methods for detection and targeted treatment of hydrosalpinx
MY204234A (en) 2018-08-27 2024-08-16 Regeneron Pharma Use of raman spectroscopy in downstream purification
CN116496394B (zh) * 2022-01-26 2024-07-23 东莞市朋志生物科技有限公司 抗s100蛋白的抗体、检测s100蛋白的试剂和试剂盒

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NZ201918A (en) 1981-09-18 1987-04-30 Genentech Inc N-terminal methionyl analogues of bovine growth hormone
US4708871A (en) 1983-03-08 1987-11-24 Commonwealth Serum Laboratories Commission Antigenically active amino acid sequences
US4816567A (en) 1983-04-08 1989-03-28 Genentech, Inc. Recombinant immunoglobin preparations
US5260203A (en) 1986-09-02 1993-11-09 Enzon, Inc. Single polypeptide chain binding molecules
US4946778A (en) 1987-09-21 1990-08-07 Genex Corporation Single polypeptide chain binding molecules
US4873192A (en) 1987-02-17 1989-10-10 The United States Of America As Represented By The Department Of Health And Human Services Process for site specific mutagenesis without phenotypic selection
EP0436597B1 (en) 1988-09-02 1997-04-02 Protein Engineering Corporation Generation and selection of recombinant varied binding proteins
US5223409A (en) 1988-09-02 1993-06-29 Protein Engineering Corp. Directed evolution of novel binding proteins
US5427908A (en) 1990-05-01 1995-06-27 Affymax Technologies N.V. Recombinant library screening methods
EP0585287B1 (en) 1990-07-10 1999-10-13 Cambridge Antibody Technology Limited Methods for producing members of specific binding pairs
GB9015198D0 (en) 1990-07-10 1990-08-29 Brien Caroline J O Binding substance
GB9022543D0 (en) 1990-10-17 1990-11-28 Wellcome Found Antibody production
CA2405246A1 (en) 1990-12-03 1992-06-11 Genentech, Inc. Enrichment method for variant proteins with alterred binding properties
EP0575485A1 (en) 1991-03-01 1993-12-29 Dyax Corp. Process for the development of binding mini-proteins
DK0580737T3 (da) 1991-04-10 2004-11-01 Scripps Research Inst Heterodimere receptorbiblioteker ved anvendelse af phagemider
CA2064544A1 (en) 1991-06-28 1992-12-29 Anthony E. Bolton Immune cell proliferation inhibitors
DE4122599C2 (de) 1991-07-08 1993-11-11 Deutsches Krebsforsch Phagemid zum Screenen von Antikörpern
WO1994012520A1 (en) 1992-11-20 1994-06-09 Enzon, Inc. Linker for linked fusion polypeptides
DE614989T1 (de) 1993-02-17 1995-09-28 Morphosys Proteinoptimierung Verfahren für in vivo Selektion von Ligandenbindende Proteine.
US5830698A (en) 1997-03-14 1998-11-03 Idec Pharmaceuticals Corporation Method for integrating genes at specific sites in mammalian cells via homologous recombination and vectors for accomplishing the same
DE19807389C2 (de) 1998-02-21 2000-08-17 Max Delbrueck Centrum Monoklonale Antikörper gegen Glycodelin A, Verfahren zu ihrer Herstellung und ihre Verwendung
US20020058292A1 (en) 2000-12-08 2002-05-16 Dillon Davin C. Ovarian tumor antigen and methods of use therefor
AU2002258518A1 (en) * 2001-03-14 2002-09-24 Millennium Pharmaceuticals, Inc. Nucleic acid molecules and proteins for the identification, assessment, prevention, and therapy of ovarian cancer
ATE549625T1 (de) 2004-03-24 2012-03-15 Tripath Imaging Inc Verfahren und zusammensetzungen zum nachweis einer zervixerkrankung
US7595380B2 (en) 2005-04-27 2009-09-29 Tripath Imaging, Inc. Monoclonal antibodies and methods for their use in the detection of cervical disease
EP2363711A1 (en) 2006-01-27 2011-09-07 Tripath Imaging, Inc. Methods for identifying patients with an increased likelihood of having ovarian cancer and compositions therefor
CN101802014A (zh) 2007-03-09 2010-08-11 三路影像公司 He4单克隆抗体和它们的使用方法
WO2009032974A2 (en) 2007-09-06 2009-03-12 Tripath Imaging, Inc. Nucleic acid-based methods for the detection of ovarian cancer

Also Published As

Publication number Publication date
WO2010102177A1 (en) 2010-09-10
JP2012524521A (ja) 2012-10-18
US20100227343A1 (en) 2010-09-09
US8476033B2 (en) 2013-07-02
AU2010221188A1 (en) 2011-10-20
US20130022998A1 (en) 2013-01-24
US8252904B2 (en) 2012-08-28
EP2403875A1 (en) 2012-01-11

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Legal Events

Date Code Title Description
FZDE Discontinued

Effective date: 20150305