JP2012524120A5 - - Google Patents
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- Publication number
- JP2012524120A5 JP2012524120A5 JP2012507283A JP2012507283A JP2012524120A5 JP 2012524120 A5 JP2012524120 A5 JP 2012524120A5 JP 2012507283 A JP2012507283 A JP 2012507283A JP 2012507283 A JP2012507283 A JP 2012507283A JP 2012524120 A5 JP2012524120 A5 JP 2012524120A5
- Authority
- JP
- Japan
- Prior art keywords
- derivative
- derivatives
- biologically active
- peptides
- proteins
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
- NTYJJOPFIAHURM-UHFFFAOYSA-N Histamine Chemical compound NCCC1=CN=CN1 NTYJJOPFIAHURM-UHFFFAOYSA-N 0.000 claims 2
- 239000004480 active ingredient Substances 0.000 claims 2
- 239000002777 nucleoside Substances 0.000 claims 2
- 125000003729 nucleotide group Chemical group 0.000 claims 2
- 210000001539 phagocyte Anatomy 0.000 claims 2
- 108090000765 processed proteins & peptides Proteins 0.000 claims 2
- 102000004196 processed proteins & peptides Human genes 0.000 claims 2
- 108090000623 proteins and genes Proteins 0.000 claims 2
- 102000004169 proteins and genes Human genes 0.000 claims 2
- 108010028921 Lipopeptides Proteins 0.000 claims 1
- MSFSPUZXLOGKHJ-UHFFFAOYSA-N Muraminsaeure Natural products OC(=O)C(C)OC1C(N)C(O)OC(CO)C1O MSFSPUZXLOGKHJ-UHFFFAOYSA-N 0.000 claims 1
- 108010013639 Peptidoglycan Proteins 0.000 claims 1
- GUGOEEXESWIERI-UHFFFAOYSA-N Terfenadine Chemical compound C1=CC(C(C)(C)C)=CC=C1C(O)CCCN1CCC(C(O)(C=2C=CC=CC=2)C=2C=CC=CC=2)CC1 GUGOEEXESWIERI-UHFFFAOYSA-N 0.000 claims 1
- 239000003242 anti bacterial agent Substances 0.000 claims 1
- 230000001387 anti-histamine Effects 0.000 claims 1
- 229940088710 antibiotic agent Drugs 0.000 claims 1
- 239000000739 antihistaminic agent Substances 0.000 claims 1
- 239000003963 antioxidant agent Substances 0.000 claims 1
- 230000003078 antioxidant effect Effects 0.000 claims 1
- 230000004071 biological effect Effects 0.000 claims 1
- 229920001222 biopolymer Polymers 0.000 claims 1
- 150000001720 carbohydrates Chemical class 0.000 claims 1
- 239000002158 endotoxin Substances 0.000 claims 1
- 229960001340 histamine Drugs 0.000 claims 1
- 230000028993 immune response Effects 0.000 claims 1
- 229940043355 kinase inhibitor Drugs 0.000 claims 1
- 150000002632 lipids Chemical class 0.000 claims 1
- 229920006008 lipopolysaccharide Polymers 0.000 claims 1
- 229910021645 metal ion Inorganic materials 0.000 claims 1
- 239000003607 modifier Substances 0.000 claims 1
- 229910052755 nonmetal Inorganic materials 0.000 claims 1
- 102000039446 nucleic acids Human genes 0.000 claims 1
- 108020004707 nucleic acids Proteins 0.000 claims 1
- 150000007523 nucleic acids Chemical class 0.000 claims 1
- 150000003833 nucleoside derivatives Chemical class 0.000 claims 1
- 125000003835 nucleoside group Chemical group 0.000 claims 1
- 239000002773 nucleotide Substances 0.000 claims 1
- 239000003757 phosphotransferase inhibitor Substances 0.000 claims 1
- IKGXIBQEEMLURG-NVPNHPEKSA-N rutin Chemical compound O[C@@H]1[C@H](O)[C@@H](O)[C@H](C)O[C@H]1OC[C@@H]1[C@@H](O)[C@H](O)[C@@H](O)[C@H](OC=2C(C3=C(O)C=C(O)C=C3OC=2C=2C=C(O)C(O)=CC=2)=O)O1 IKGXIBQEEMLURG-NVPNHPEKSA-N 0.000 claims 1
- 125000003396 thiol group Chemical class [H]S* 0.000 claims 1
- 239000011782 vitamin Substances 0.000 claims 1
- 229940088594 vitamin Drugs 0.000 claims 1
- 229930003231 vitamin Natural products 0.000 claims 1
- 235000013343 vitamin Nutrition 0.000 claims 1
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US17094509P | 2009-04-20 | 2009-04-20 | |
| US61/170,945 | 2009-04-20 | ||
| PCT/US2010/031559 WO2010123798A2 (en) | 2009-04-20 | 2010-04-19 | Compositions for transfection of biomolecules into cells |
Related Child Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2015171776A Division JP6295235B2 (ja) | 2009-04-20 | 2015-09-01 | 生体分子を細胞へトランスフェクトするための組成物 |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2012524120A JP2012524120A (ja) | 2012-10-11 |
| JP2012524120A5 true JP2012524120A5 (enExample) | 2013-06-06 |
| JP6101077B2 JP6101077B2 (ja) | 2017-03-22 |
Family
ID=43011700
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2012507283A Expired - Fee Related JP6101077B2 (ja) | 2009-04-20 | 2010-04-19 | 生体分子を細胞へトランスフェクトするための組成物 |
| JP2015171776A Expired - Fee Related JP6295235B2 (ja) | 2009-04-20 | 2015-09-01 | 生体分子を細胞へトランスフェクトするための組成物 |
Family Applications After (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2015171776A Expired - Fee Related JP6295235B2 (ja) | 2009-04-20 | 2015-09-01 | 生体分子を細胞へトランスフェクトするための組成物 |
Country Status (7)
| Country | Link |
|---|---|
| US (1) | US11738084B2 (enExample) |
| EP (1) | EP2421952B1 (enExample) |
| JP (2) | JP6101077B2 (enExample) |
| KR (1) | KR101742332B1 (enExample) |
| AU (1) | AU2010239463B2 (enExample) |
| HU (1) | HUE028642T2 (enExample) |
| WO (1) | WO2010123798A2 (enExample) |
Families Citing this family (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP6101077B2 (ja) * | 2009-04-20 | 2017-03-22 | ガレンバイオ、インコーポレイテッド | 生体分子を細胞へトランスフェクトするための組成物 |
| JP6208767B2 (ja) * | 2012-10-23 | 2017-10-04 | エコール スペリュール デ フィジーク エ シミ アンドゥストリエル デ ラ ヴィル デ パリ | 複数回逐次的に形成し、切断することができる可逆的共有結合を含む粒子 |
| CN103849650B (zh) * | 2013-10-14 | 2018-08-03 | 王深明 | 功能化纳米姜黄素的基因导入材料及制备方法 |
| AR103173A1 (es) | 2014-12-22 | 2017-04-19 | Novarits Ag | Productos farmacéuticos y composiciones líquidas estables de anticuerpos il-17 |
| SG11201805375PA (en) | 2016-02-04 | 2018-07-30 | Stem Cell Theranostics Inc | Pharmaceutical compositions and methods for countering chemotherapy induced cardiotoxicity |
| CN108330102B (zh) * | 2018-03-14 | 2020-02-14 | 江南大学 | 一株泰妙菌素单克隆抗体杂交瘤细胞株及其应用 |
Family Cites Families (22)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPS4954515A (enExample) | 1972-10-03 | 1974-05-27 | ||
| US5602244A (en) | 1988-05-26 | 1997-02-11 | Competitive Technologies, Inc. | Polynucleotide phosphorodithioate compounds |
| JP2524406B2 (ja) * | 1988-07-05 | 1996-08-14 | 田辺製薬株式会社 | パイロジェン定量方法 |
| KR100191223B1 (ko) * | 1989-07-28 | 1999-06-15 | 둘락 노먼 씨. | 인터루킨-4의 정제방법 및 이를 함유하는 약제학적 조성물 |
| US6001982A (en) | 1993-07-29 | 1999-12-14 | Isis Pharmaceuticals, Inc. | Synthesis of oligonucleotides |
| US5962674A (en) | 1995-06-01 | 1999-10-05 | Hybridon, Inc. | Synthesis of oligonucleotides containing alkylphosphonate internucleoside linkages |
| JPH10510433A (ja) | 1995-06-06 | 1998-10-13 | アイシス・ファーマシューティカルス・インコーポレーテッド | 高いキラル純度のホスホロチオエート結合を有するオリゴヌクレオチド |
| US5985662A (en) | 1995-07-13 | 1999-11-16 | Isis Pharmaceuticals Inc. | Antisense inhibition of hepatitis B virus replication |
| US5734041A (en) | 1995-10-20 | 1998-03-31 | Mcgill University | Preparation of chiral phosphorothioate oligomers |
| US6194469B1 (en) | 1998-12-11 | 2001-02-27 | Board Of Trustees Operating Michigan State Univeristy | Method for inhibiting cyclooxygenase and inflammation using cherry bioflavonoids |
| ES2243229T3 (es) * | 1999-02-03 | 2005-12-01 | Powderject Res Ltd | Formulaciones de particulas de hidrogel. |
| US7195780B2 (en) * | 2002-10-21 | 2007-03-27 | University Of Florida | Nanoparticle delivery system |
| AU2001273128C1 (en) * | 2000-06-29 | 2006-09-21 | Corixa Corporation | Compositions and methods for the diagnosis and treatment of herpes simplex virus infection |
| US20030139364A1 (en) * | 2001-10-12 | 2003-07-24 | University Of Iowa Research Foundation | Methods and products for enhancing immune responses using imidazoquinoline compounds |
| ES2263859T3 (es) * | 2003-02-18 | 2006-12-16 | Clinique La Prairie Research Sa | Composiciones qu4e comprenden hemoglobina fetal y endotoxina bacteriana y opcionalmente componentes de higado fetal adicionales. |
| US7785769B2 (en) * | 2003-07-25 | 2010-08-31 | The United States of America as reprsented by the Secretary of the Navy | Immobilization of oligonucleotides and proteins in sugar-containing hydrogels |
| CA2606349C (en) * | 2005-01-28 | 2019-03-05 | Galen Bio, Inc. | Immunologically active compositions |
| US20070020620A1 (en) | 2005-07-14 | 2007-01-25 | Finn M G | Compositions and methods for coupling a plurality of compounds to a scaffold |
| US20070281036A1 (en) * | 2005-12-19 | 2007-12-06 | University Of Vermont And State Agricultural College | System and method of delivering a desired material to a cell |
| US8288124B2 (en) * | 2008-11-20 | 2012-10-16 | Abbott Laboratories | Cloning, expression and purification of recombinant porcine intrinsic factor for use in diagnostic assay |
| JP6101077B2 (ja) * | 2009-04-20 | 2017-03-22 | ガレンバイオ、インコーポレイテッド | 生体分子を細胞へトランスフェクトするための組成物 |
| ES2397909B1 (es) * | 2011-05-05 | 2014-06-06 | Universidad De Zaragoza | Procedimiento de obtención de materiales multifuncionalizados |
-
2010
- 2010-04-19 JP JP2012507283A patent/JP6101077B2/ja not_active Expired - Fee Related
- 2010-04-19 HU HUE10767573A patent/HUE028642T2/en unknown
- 2010-04-19 AU AU2010239463A patent/AU2010239463B2/en not_active Ceased
- 2010-04-19 WO PCT/US2010/031559 patent/WO2010123798A2/en not_active Ceased
- 2010-04-19 US US13/264,814 patent/US11738084B2/en active Active
- 2010-04-19 KR KR1020117027684A patent/KR101742332B1/ko not_active Expired - Fee Related
- 2010-04-19 EP EP10767573.8A patent/EP2421952B1/en not_active Not-in-force
-
2015
- 2015-09-01 JP JP2015171776A patent/JP6295235B2/ja not_active Expired - Fee Related
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