JP2012519711A5 - - Google Patents
Download PDFInfo
- Publication number
- JP2012519711A5 JP2012519711A5 JP2011553153A JP2011553153A JP2012519711A5 JP 2012519711 A5 JP2012519711 A5 JP 2012519711A5 JP 2011553153 A JP2011553153 A JP 2011553153A JP 2011553153 A JP2011553153 A JP 2011553153A JP 2012519711 A5 JP2012519711 A5 JP 2012519711A5
- Authority
- JP
- Japan
- Prior art keywords
- antibody
- drug conjugate
- antibody drug
- pharmaceutical composition
- cancer
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US15814309P | 2009-03-06 | 2009-03-06 | |
| US61/158,143 | 2009-03-06 | ||
| PCT/US2010/026429 WO2010111018A1 (en) | 2009-03-06 | 2010-03-05 | Antibody drug conjugates (adc) that bind to 24p4c12 proteins |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2012519711A JP2012519711A (ja) | 2012-08-30 |
| JP2012519711A5 true JP2012519711A5 (https=) | 2013-04-18 |
Family
ID=42781369
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2011553153A Pending JP2012519711A (ja) | 2009-03-06 | 2010-03-05 | ２４ｐ４ｃ１２タンパク質に結合する抗体薬物結合体（ａｄｃ） |
Country Status (15)
| Country | Link |
|---|---|
| US (2) | US8309093B2 (https=) |
| EP (1) | EP2403524A4 (https=) |
| JP (1) | JP2012519711A (https=) |
| KR (1) | KR20120034591A (https=) |
| CN (1) | CN102448486A (https=) |
| AU (1) | AU2010229192A1 (https=) |
| BR (1) | BRPI1013645A2 (https=) |
| CA (1) | CA2754531A1 (https=) |
| IL (1) | IL214983A0 (https=) |
| MX (1) | MX2011009281A (https=) |
| RU (1) | RU2011140491A (https=) |
| SG (1) | SG174259A1 (https=) |
| TW (1) | TW201043249A (https=) |
| WO (1) | WO2010111018A1 (https=) |
| ZA (1) | ZA201107293B (https=) |
Families Citing this family (30)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US8309093B2 (en) * | 2009-03-06 | 2012-11-13 | Agensys, Inc. | Antibody drug conjugates (ADC) that bind to 24P4C12 proteins |
| CN103561771B (zh) | 2011-03-17 | 2019-01-04 | 伯明翰大学 | 重新定向的免疫治疗 |
| KR102356286B1 (ko) * | 2011-05-27 | 2022-02-08 | 암브룩스, 인코포레이티드 | 비-천연 아미노산 연결된 돌라스타틴 유도체를 함유하는 조성물, 이를 수반하는 방법, 및 용도 |
| TWI606063B (zh) * | 2012-08-23 | 2017-11-21 | 艾澤西公司 | 結合至１５８ｐ１ｄ７蛋白之抗體藥物結合物（ａｄｃ） |
| WO2014089177A2 (en) | 2012-12-04 | 2014-06-12 | Massachusetts Institute Of Technology | Compounds, conjugates and compositions of epipolythiodiketopiperazines and polythiodiketopiperazines |
| US9089614B2 (en) | 2012-12-21 | 2015-07-28 | Bioalliance C.V. | Hydrophilic self-immolative linkers and conjugates thereof |
| EP2777714A1 (en) | 2013-03-15 | 2014-09-17 | NBE-Therapeutics LLC | Method of producing an immunoligand/payload conjugate by means of a sequence-specific transpeptidase enzyme |
| FR3005051A1 (fr) * | 2013-04-25 | 2014-10-31 | Pf Medicament | Derives de la dolastatine 10 et d'auristatines |
| EP3096797A1 (en) * | 2014-01-24 | 2016-11-30 | F. Hoffmann-La Roche AG | Methods of using anti-steap1 antibodies and immunoconjugates |
| AR099812A1 (es) | 2014-03-21 | 2016-08-17 | Abbvie Inc | Anticuerpos y conjugados de anticuerpo y fármaco anti-egfr |
| HUE047952T2 (hu) | 2014-04-25 | 2020-05-28 | Pf Medicament | Ellenanyag-drog konjugátum és alkalmazása rák kezelésében történõ alkalmazásra |
| HRP20190888T8 (hr) | 2014-04-25 | 2019-10-04 | Pierre Fabre Médicament | Konjugat antitijela za igf-1r i lijeka i njegova upotreba u liječenju karcinoma |
| AU2015277100A1 (en) * | 2014-06-20 | 2017-02-02 | Abgenomics International Inc. | HER2 antibody-drug conjugates |
| US9950077B2 (en) | 2014-06-20 | 2018-04-24 | Bioalliance C.V. | Anti-folate receptor alpha (FRA) antibody-drug conjugates and methods of using thereof |
| EP3160513B1 (en) | 2014-06-30 | 2020-02-12 | Glykos Finland Oy | Saccharide derivative of a toxic payload and antibody conjugates thereof |
| WO2016102679A1 (en) | 2014-12-23 | 2016-06-30 | Nbe-Therapeutics Ag | Binding protein drug conjugates comprising anthracycline derivatives |
| IL260289B (en) | 2016-01-08 | 2022-08-01 | Bioalliance Cv | Tetravalent anti-psgl-1 antibodies and uses thereof |
| WO2017197045A1 (en) | 2016-05-11 | 2017-11-16 | Movassaghi Mohammad | Convergent and enantioselective total synthesis of communesin analogs |
| JP2019524651A (ja) | 2016-06-08 | 2019-09-05 | アッヴィ・インコーポレイテッド | 抗ｃｄ９８抗体及び抗体薬物コンジュゲート |
| US20200147235A1 (en) | 2016-06-08 | 2020-05-14 | Abbvie Inc. | Anti-cd98 antibodies and antibody drug conjugates |
| WO2017214322A1 (en) | 2016-06-08 | 2017-12-14 | Abbvie Inc. | Anti-b7-h3 antibodies and antibody drug conjugates |
| AU2017279550A1 (en) | 2016-06-08 | 2019-01-03 | Abbvie Inc. | Anti-B7-H3 antibodies and antibody drug conjugates |
| MX2018015285A (es) | 2016-06-08 | 2019-09-18 | Abbvie Inc | Anticuerpos anti-b7-h3 y conjugados de anticuerpo y farmaco. |
| US11932650B2 (en) | 2017-05-11 | 2024-03-19 | Massachusetts Institute Of Technology | Potent agelastatin derivatives as modulators for cancer invasion and metastasis |
| SG11202001930QA (en) | 2017-09-07 | 2020-04-29 | Dragonfly Therapeutics Inc | Proteins binding nkg2d, cd16 and a tumor-associated antigen |
| US10640508B2 (en) | 2017-10-13 | 2020-05-05 | Massachusetts Institute Of Technology | Diazene directed modular synthesis of compounds with quaternary carbon centers |
| EP3897851A2 (en) | 2018-12-17 | 2021-10-27 | Revitope Limited | Twin immune cell engager |
| US11535634B2 (en) | 2019-06-05 | 2022-12-27 | Massachusetts Institute Of Technology | Compounds, conjugates, and compositions of epipolythiodiketopiperazines and polythiodiketopiperazines and uses thereof |
| AR124681A1 (es) | 2021-01-20 | 2023-04-26 | Abbvie Inc | Conjugados anticuerpo-fármaco anti-egfr |
| WO2022182415A1 (en) | 2021-02-24 | 2022-09-01 | Massachusetts Institute Of Technology | Himastatin derivatives, and processes of preparation thereof, and uses thereof |
Family Cites Families (37)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4742000A (en) | 1986-05-02 | 1988-05-03 | University Of Chicago | Antibody to human progesterone receptor and diagnostic materials and methods |
| US5530101A (en) | 1988-12-28 | 1996-06-25 | Protein Design Labs, Inc. | Humanized immunoglobulins |
| US6130237A (en) | 1996-09-12 | 2000-10-10 | Cancer Research Campaign Technology Limited | Condensed N-aclyindoles as antitumor agents |
| US20030082546A1 (en) | 1996-11-06 | 2003-05-01 | Genentech, Inc. | Secreted and transmembrane polypeptides and nucleic acids encoding the same |
| US6800746B2 (en) | 1997-02-25 | 2004-10-05 | Corixa Corporation | Compositions and methods for the therapy and diagnosis of prostate cancer |
| US20030068623A1 (en) | 1997-06-16 | 2003-04-10 | Genentech, Inc. | Secreted and transmembrane polypeptides and nucleic acids encoding the same |
| US7109318B2 (en) | 1997-06-16 | 2006-09-19 | Genentech, Inc. | Nucleic acids encoding PRO830 |
| US7393663B2 (en) | 1997-08-01 | 2008-07-01 | Serono Genetics Institute S.A. | Expressed sequence tags and encoded human proteins |
| US7160985B2 (en) | 1997-10-29 | 2007-01-09 | Genentech, Inc. | Pro180 polypeptide |
| AU764441B2 (en) | 1998-02-09 | 2003-08-21 | Genset S.A. | cDNAs encoding secreted proteins |
| US6747137B1 (en) | 1998-02-13 | 2004-06-08 | Genome Therapeutics Corporation | Nucleic acid sequences relating to Candida albicans for diagnostics and therapeutics |
| US6551795B1 (en) | 1998-02-18 | 2003-04-22 | Genome Therapeutics Corporation | Nucleic acid and amino acid sequences relating to pseudomonas aeruginosa for diagnostics and therapeutics |
| US20030050465A1 (en) | 1998-08-10 | 2003-03-13 | Genentech, Inc. | Secreted and transmembrane polypeptides and nucleic acids encoding the same |
| US7109003B2 (en) | 1998-12-23 | 2006-09-19 | Abgenix, Inc. | Methods for expressing and recovering human monoclonal antibodies to CTLA-4 |
| US6682736B1 (en) * | 1998-12-23 | 2004-01-27 | Abgenix, Inc. | Human monoclonal antibodies to CTLA-4 |
| US20030009013A1 (en) | 1998-12-30 | 2003-01-09 | Genentech, Inc. | Secreted and transmembrane polypeptides and nucleic acids encoding the same |
| CA2296792A1 (en) | 1999-02-26 | 2000-08-26 | Genset S.A. | Expressed sequence tags and encoded human proteins |
| US7244827B2 (en) | 2000-04-12 | 2007-07-17 | Agensys, Inc. | Nucleic acid and corresponding protein entitled 24P4C12 useful in treatment and detection of cancer |
| US6943235B1 (en) | 1999-04-12 | 2005-09-13 | Agensys, Inc. | Transmembrane protein expressed in prostate cancer |
| WO2000061746A1 (en) | 1999-04-12 | 2000-10-19 | Agensys, Inc. | 13 transmembrane protein expressed in prostate cancer |
| EP1074617A3 (en) | 1999-07-29 | 2004-04-21 | Research Association for Biotechnology | Primers for synthesising full-length cDNA and their use |
| FR2800750B1 (fr) | 1999-11-05 | 2003-01-31 | Centre Nat Rech Scient | Proteines membranaires ctl (choline transporter like) impliquees dans le transport de la choline |
| US20020192763A1 (en) | 2000-04-17 | 2002-12-19 | Jiangchun Xu | Compositions and methods for the therapy and diagnosis of prostate cancer |
| US7442765B2 (en) | 2000-08-24 | 2008-10-28 | Genentech, Inc. | Secreted transmembrane polypeptides and nucleic acids encoding the same |
| US20030099974A1 (en) | 2001-07-18 | 2003-05-29 | Millennium Pharmaceuticals, Inc. | Novel genes, compositions, kits and methods for identification, assessment, prevention, and therapy of breast cancer |
| US20030073623A1 (en) | 2001-07-30 | 2003-04-17 | Drmanac Radoje T. | Novel nucleic acid sequences obtained from various cDNA libraries |
| AR039067A1 (es) * | 2001-11-09 | 2005-02-09 | Pfizer Prod Inc | Anticuerpos para cd40 |
| US7378492B2 (en) | 2002-02-20 | 2008-05-27 | Incyte Corporation | CD40-related receptor that binds CD40L |
| DK1545613T3 (da) * | 2002-07-31 | 2011-11-14 | Seattle Genetics Inc | Auristatinkonjugater og deres anvendelse til behandling af cancer, en autoimmun sygdom eller en infektiøs sygdom |
| EP1565200A4 (en) * | 2002-11-27 | 2009-06-24 | Agensys Inc | NUCLEIC ACID 24P4C12 AND CORRESPONDING PROTEIN FOR THE TREATMENT AND DETECTION OF CANCER |
| EP2478912B1 (en) * | 2003-11-06 | 2016-08-31 | Seattle Genetics, Inc. | Auristatin conjugates with anti-HER2 or anti-CD22 antibodies and their use in therapy |
| CA2575791A1 (en) | 2004-08-03 | 2006-02-16 | Dyax Corp. | Hk1-binding proteins |
| DK1912677T3 (da) * | 2005-06-20 | 2014-01-13 | Psma Dev Company L L C | PSMA-antistof-lægemiddel-konjugater |
| EP2050335A1 (en) | 2006-02-17 | 2009-04-22 | Genentech, Inc. | Gene disruptions, compositions and methods relating thereto |
| PT2185574E (pt) * | 2007-09-07 | 2013-08-26 | Agensys Inc | Anticorpos e moléculas relacionadas que se ligam a proteínas 24p4c12 |
| US8039597B2 (en) * | 2007-09-07 | 2011-10-18 | Agensys, Inc. | Antibodies and related molecules that bind to 24P4C12 proteins |
| US8309093B2 (en) * | 2009-03-06 | 2012-11-13 | Agensys, Inc. | Antibody drug conjugates (ADC) that bind to 24P4C12 proteins |
-
2010
- 2010-03-05 US US12/718,902 patent/US8309093B2/en active Active
- 2010-03-05 RU RU2011140491/10A patent/RU2011140491A/ru not_active Application Discontinuation
- 2010-03-05 AU AU2010229192A patent/AU2010229192A1/en not_active Abandoned
- 2010-03-05 KR KR1020117023550A patent/KR20120034591A/ko not_active Withdrawn
- 2010-03-05 MX MX2011009281A patent/MX2011009281A/es unknown
- 2010-03-05 WO PCT/US2010/026429 patent/WO2010111018A1/en not_active Ceased
- 2010-03-05 JP JP2011553153A patent/JP2012519711A/ja active Pending
- 2010-03-05 CN CN2010800203364A patent/CN102448486A/zh active Pending
- 2010-03-05 EP EP10756560A patent/EP2403524A4/en not_active Withdrawn
- 2010-03-05 CA CA2754531A patent/CA2754531A1/en not_active Abandoned
- 2010-03-05 SG SG2011063930A patent/SG174259A1/en unknown
- 2010-03-05 BR BRPI1013645A patent/BRPI1013645A2/pt not_active IP Right Cessation
- 2010-03-08 TW TW099106660A patent/TW201043249A/zh unknown
-
2011
- 2011-09-05 IL IL214983A patent/IL214983A0/en unknown
- 2011-10-05 ZA ZA2011/07293A patent/ZA201107293B/en unknown
-
2012
- 2012-11-08 US US13/672,419 patent/US20130136756A1/en not_active Abandoned
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| JP2012519711A5 (https=) | ||
| RU2011140491A (ru) | Конъюгаты антитело-лекарственное средство, которые связывают белки 24р4с12 | |
| JP2013543498A5 (https=) | ||
| RU2483080C2 (ru) | Антитела и иммуноконъюгаты и их применение | |
| RU2423382C1 (ru) | Композиции и способы диагностики и лечения опухоли | |
| JP2017110002A5 (https=) | ||
| ES2879799T3 (es) | Anticuerpo anti-HER2 y conjugado del mismo | |
| JP2025113404A5 (https=) | ||
| JP6333882B2 (ja) | 抗体−薬剤コンジュゲート | |
| JP2013518912A5 (https=) | ||
| JP2018534933A5 (https=) | ||
| US10792370B2 (en) | Antibody-drug conjugate | |
| JP2010523469A5 (https=) | ||
| SI2424569T1 (en) | Immunoconjugated anti-mesothelin and their use | |
| JP2016063817A5 (https=) | ||
| JP2008546780A5 (https=) | ||
| JP2009506790A5 (https=) | ||
| JP2008529497A5 (https=) | ||
| JP2010537671A5 (https=) | ||
| NZ613647A (en) | Uses of immunoconjugates targeting cd138 | |
| IL319612A (en) | Antibody drug conjugates (ADC) that bind to 191P4D12 proteins | |
| IL278574B2 (en) | Glycan-interacting compounds and methods of use | |
| JP2010526821A5 (https=) | ||
| IL184803A (en) | Purified antibodies against epha2, methods for their production, pharmaceutical compositions comprising them and use thereof in the preparation of medicaments for treating cancer | |
| RU2008141171A (ru) | Анти-тат226 антитела и иммуноконъюгаты |