JP2012517427A5 - - Google Patents
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- Publication number
- JP2012517427A5 JP2012517427A5 JP2011549167A JP2011549167A JP2012517427A5 JP 2012517427 A5 JP2012517427 A5 JP 2012517427A5 JP 2011549167 A JP2011549167 A JP 2011549167A JP 2011549167 A JP2011549167 A JP 2011549167A JP 2012517427 A5 JP2012517427 A5 JP 2012517427A5
- Authority
- JP
- Japan
- Prior art keywords
- pharmaceutical composition
- lung cancer
- cell type
- azacytidine
- small cell
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US15147909P | 2009-02-10 | 2009-02-10 | |
| US61/151,479 | 2009-02-10 | ||
| PCT/US2010/000361 WO2010093435A1 (en) | 2009-02-10 | 2010-02-09 | Methods for treating non-small cell lung cancer using 5-azacytidine |
Related Child Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2015032530A Division JP2015131822A (ja) | 2009-02-10 | 2015-02-23 | ５−アザシチジンを用いる、非小細胞肺癌の治療方法 |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2012517427A JP2012517427A (ja) | 2012-08-02 |
| JP2012517427A5 true JP2012517427A5 (https=) | 2013-03-21 |
| JP6063628B2 JP6063628B2 (ja) | 2017-01-18 |
Family
ID=42115561
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2011549167A Active JP6063628B2 (ja) | 2009-02-10 | 2010-02-09 | ５−アザシチジンを用いる、非小細胞肺癌の治療方法 |
| JP2015032530A Pending JP2015131822A (ja) | 2009-02-10 | 2015-02-23 | ５−アザシチジンを用いる、非小細胞肺癌の治療方法 |
Family Applications After (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2015032530A Pending JP2015131822A (ja) | 2009-02-10 | 2015-02-23 | ５−アザシチジンを用いる、非小細胞肺癌の治療方法 |
Country Status (5)
| Country | Link |
|---|---|
| US (2) | US8492361B2 (https=) |
| EP (1) | EP2396007A1 (https=) |
| JP (2) | JP6063628B2 (https=) |
| CA (1) | CA2789365A1 (https=) |
| WO (1) | WO2010093435A1 (https=) |
Families Citing this family (18)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2010093435A1 (en) | 2009-02-10 | 2010-08-19 | Celgene International Sarl | Methods for treating non-small cell lung cancer using 5-azacytidine |
| WO2013022872A1 (en) | 2011-08-10 | 2013-02-14 | Celgene Corporation | Gene methylation biomarkers and methods of use thereof |
| US20130244950A1 (en) | 2011-09-26 | 2013-09-19 | Celgene Corporation | Combination therapy for chemoresistant cancers |
| US9125884B2 (en) | 2011-11-01 | 2015-09-08 | Celgene Corporation | Methods for treating cancers using oral formulations of cytidine analogs |
| TWI615143B (zh) * | 2012-02-24 | 2018-02-21 | 標誌製藥公司 | 使用ｔｏｒ激酶抑制劑組合療法以治療癌症之方法 |
| US9782427B2 (en) * | 2013-04-17 | 2017-10-10 | Signal Pharmaceuticals, Llc | Methods for treating cancer using TOR kinase inhibitor combination therapy |
| WO2014180996A1 (en) * | 2013-05-10 | 2014-11-13 | Embl | Use of 5-azacytidine to inhibit nonsense-mediated rna decay (nmd) |
| KR102359214B1 (ko) | 2014-04-04 | 2022-02-07 | 델 마 파마슈티컬스 | 폐의 비소세포 암종 및 난소암을 치료하기 위한 디안하이드로갈락티톨 및 이의 유사체 또는 유도체 |
| US9718824B2 (en) | 2014-04-16 | 2017-08-01 | Signal Pharmaceuticals, Llc | Solid forms comprising 7-(6-(2-hydroxypropan-2-yl)pyridin-3-yl)-1-((trans)-4-methoxycyclohexyl)-3,4-dihydropyrazino[2,3-b]pyrazin-2(1H)-one, and a coformer, compositions and methods of use thereof |
| EP3131552B1 (en) | 2014-04-16 | 2020-07-15 | Signal Pharmaceuticals, LLC | Methods for treating cancer using tor kinase inhibitor combination therapy |
| WO2015195786A2 (en) * | 2014-06-17 | 2015-12-23 | Celgene Corporation | Methods for treating cancers using oral formulations of cytidine analogs |
| WO2016040238A1 (en) * | 2014-09-08 | 2016-03-17 | Celgene Corporation | Methods for treating a disease or disorder using oral formulations of cytidine analogs in combination with an anti-pd1 or anti-pdl1 monoclonal antibody |
| US9801983B2 (en) | 2014-12-18 | 2017-10-31 | Cook Medical Technologies Llc | Medical devices for delivering a bioactive to a point of treatment and methods of making medical devices |
| WO2016201337A1 (en) * | 2015-06-12 | 2016-12-15 | Immungene, Inc. | Engineered antibody-interferon fusion molecules for the treatment of glucose-regulated protein 94 (grp94) expressing cancers |
| DK3383406T3 (da) | 2015-12-03 | 2022-01-10 | Epidestiny Inc | Sammensætninger indeholdende decitabin, 5-azacytidin og tetrahydrouridin og anvendelser deraf |
| EP3641772B1 (en) | 2017-06-22 | 2023-08-02 | Celgene Corporation | Treatment of hepatocellular carcinoma characterized by hepatitis b virus infection |
| JP7017638B2 (ja) * | 2018-02-07 | 2022-02-08 | ラブレス バイオメディカル リサーチ インスティテュート | 吸入可能な乾燥粉末シチジン類似体組成物及び癌への治療として使用する方法 |
| JP7089603B2 (ja) | 2018-06-11 | 2022-06-22 | ザ リージェンツ オブ ザ ユニバーシティ オブ カリフォルニア | 眼疾患を治療するための脱メチル化 |
Family Cites Families (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US20060063735A1 (en) * | 2004-09-17 | 2006-03-23 | Supergen, Inc. | Salts of 5-azacytidine |
| EP2211870A1 (en) | 2007-11-01 | 2010-08-04 | Celgene Corporation | Cytidine analogs for treatment of myelodysplastic syndromes |
| EP3782612B1 (en) | 2008-05-15 | 2023-11-08 | Celgene Corporation | Oral formulations of cytidine analogs and methods of use thereof |
| WO2010093435A1 (en) | 2009-02-10 | 2010-08-19 | Celgene International Sarl | Methods for treating non-small cell lung cancer using 5-azacytidine |
| WO2013022872A1 (en) | 2011-08-10 | 2013-02-14 | Celgene Corporation | Gene methylation biomarkers and methods of use thereof |
-
2010
- 2010-02-09 WO PCT/US2010/000361 patent/WO2010093435A1/en not_active Ceased
- 2010-02-09 EP EP10704434A patent/EP2396007A1/en not_active Withdrawn
- 2010-02-09 CA CA2789365A patent/CA2789365A1/en not_active Abandoned
- 2010-02-09 US US13/148,636 patent/US8492361B2/en active Active
- 2010-02-09 JP JP2011549167A patent/JP6063628B2/ja active Active
-
2013
- 2013-06-07 US US13/913,248 patent/US8841277B2/en not_active Expired - Fee Related
-
2015
- 2015-02-23 JP JP2015032530A patent/JP2015131822A/ja active Pending
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