JP2012513468A5 - - Google Patents
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- Publication number
- JP2012513468A5 JP2012513468A5 JP2011543609A JP2011543609A JP2012513468A5 JP 2012513468 A5 JP2012513468 A5 JP 2012513468A5 JP 2011543609 A JP2011543609 A JP 2011543609A JP 2011543609 A JP2011543609 A JP 2011543609A JP 2012513468 A5 JP2012513468 A5 JP 2012513468A5
- Authority
- JP
- Japan
- Prior art keywords
- haloalkyl
- alkyl
- halo
- cyano
- alkoxy
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
- 0 CNC(Nc1ccccc1)=* Chemical compound CNC(Nc1ccccc1)=* 0.000 description 7
- IQNPOSTZBOXWBW-RWWKDMOOSA-N O=C(c1ccc(C(F)(F)F)cc1)Nc1cc(CC(CC2)[C@H](CS(c([s]3)ccc3Cl)(=O)=O)C2C2)c2cc1 Chemical compound O=C(c1ccc(C(F)(F)F)cc1)Nc1cc(CC(CC2)[C@H](CS(c([s]3)ccc3Cl)(=O)=O)C2C2)c2cc1 IQNPOSTZBOXWBW-RWWKDMOOSA-N 0.000 description 2
- IMCUKDXRJUSXAZ-AVKWCDSFSA-N CCCC(C1)[C@@H](CS(c([s]2)ccc2Cl)(=O)=O)CCc2c1ccc(OC(Cc1ccc(C(F)(F)F)cc1)=O)c2 Chemical compound CCCC(C1)[C@@H](CS(c([s]2)ccc2Cl)(=O)=O)CCc2c1ccc(OC(Cc1ccc(C(F)(F)F)cc1)=O)c2 IMCUKDXRJUSXAZ-AVKWCDSFSA-N 0.000 description 1
- OHNRHGPLVQUXQH-ANYOKISRSA-N CCCC(C1)[C@H](CS(c([s]2)ccc2Cl)(=O)=O)CCc(cc2)c1cc2OC(c1ccc(C(F)(F)F)cc1)=O Chemical compound CCCC(C1)[C@H](CS(c([s]2)ccc2Cl)(=O)=O)CCc(cc2)c1cc2OC(c1ccc(C(F)(F)F)cc1)=O OHNRHGPLVQUXQH-ANYOKISRSA-N 0.000 description 1
- NYPOJKPKOWBKFI-BKGZJSHASA-N CCCC(Cc1c(CC2)ccc(NC(C)/C=C/c(cc3)ccc3F)c1)[C@@H]2NS(c1ccc(C)[s]1)(=O)=O Chemical compound CCCC(Cc1c(CC2)ccc(NC(C)/C=C/c(cc3)ccc3F)c1)[C@@H]2NS(c1ccc(C)[s]1)(=O)=O NYPOJKPKOWBKFI-BKGZJSHASA-N 0.000 description 1
- DOWWPENZCVJERE-SLAHTUFOSA-N O=C(CCOc(cc1)ccc1F)Oc1cc(C[C@@H](CC2)[C@H](C[Os]c([s]3)ccc3Cl)N2C2)c2cc1 Chemical compound O=C(CCOc(cc1)ccc1F)Oc1cc(C[C@@H](CC2)[C@H](C[Os]c([s]3)ccc3Cl)N2C2)c2cc1 DOWWPENZCVJERE-SLAHTUFOSA-N 0.000 description 1
- IFPBWXNUXWIDSN-QLPKVWCKSA-N O=S(c1ccc[s]1)(N[C@@H]([C@H](CC1)C2)[C@@H]1Cc1c2cccc1)=O Chemical compound O=S(c1ccc[s]1)(N[C@@H]([C@H](CC1)C2)[C@@H]1Cc1c2cccc1)=O IFPBWXNUXWIDSN-QLPKVWCKSA-N 0.000 description 1
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US13975108P | 2008-12-22 | 2008-12-22 | |
| US61/139,751 | 2008-12-22 | ||
| PCT/US2009/068937 WO2010075255A2 (en) | 2008-12-22 | 2009-12-21 | Methods for treating or preventing cancer and neurodegenerative diseases |
Related Child Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2014165817A Division JP2014210820A (ja) | 2008-12-22 | 2014-08-18 | 癌及び神経変性疾患の治療又は予防方法 |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2012513468A JP2012513468A (ja) | 2012-06-14 |
| JP2012513468A5 true JP2012513468A5 (https=) | 2013-01-31 |
Family
ID=41692962
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2011543609A Pending JP2012513468A (ja) | 2008-12-22 | 2009-12-21 | 癌及び神経変性疾患の治療又は予防方法 |
| JP2014165817A Withdrawn JP2014210820A (ja) | 2008-12-22 | 2014-08-18 | 癌及び神経変性疾患の治療又は予防方法 |
Family Applications After (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2014165817A Withdrawn JP2014210820A (ja) | 2008-12-22 | 2014-08-18 | 癌及び神経変性疾患の治療又は予防方法 |
Country Status (6)
| Country | Link |
|---|---|
| US (2) | US9056857B2 (https=) |
| EP (1) | EP2379073A2 (https=) |
| JP (2) | JP2012513468A (https=) |
| AU (1) | AU2009330192A1 (https=) |
| CA (1) | CA2747805A1 (https=) |
| WO (1) | WO2010075255A2 (https=) |
Families Citing this family (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US10751328B2 (en) | 2013-10-25 | 2020-08-25 | Oral Alpan | Therapy for chronic idiopathic urticaria, anaphylaxis and angioedema |
| CN110072523A (zh) | 2016-09-07 | 2019-07-30 | 格利亚有限责任公司 | 通过脑神经的药理皮肤激活来治疗与神经退行性病症相关的症状 |
| US12338495B2 (en) | 2017-05-02 | 2025-06-24 | Sanford Burnham Prebys Medical Discovery Institute | Methods of diagnosing and treating Alzheimer's disease |
| CA3257890A1 (en) * | 2022-06-03 | 2023-12-07 | Freenome Holdings, Inc. | MARKERS FOR THE EARLY DETECTION OF PROLIFERATIVE COLONIC CELL DISORDERS |
Family Cites Families (16)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US3536809A (en) | 1969-02-17 | 1970-10-27 | Alza Corp | Medication method |
| US3598123A (en) | 1969-04-01 | 1971-08-10 | Alza Corp | Bandage for administering drugs |
| US3845770A (en) | 1972-06-05 | 1974-11-05 | Alza Corp | Osmatic dispensing device for releasing beneficial agent |
| US3916899A (en) | 1973-04-25 | 1975-11-04 | Alza Corp | Osmotic dispensing device with maximum and minimum sizes for the passageway |
| US4008719A (en) | 1976-02-02 | 1977-02-22 | Alza Corporation | Osmotic system having laminar arrangement for programming delivery of active agent |
| IE58110B1 (en) | 1984-10-30 | 1993-07-14 | Elan Corp Plc | Controlled release powder and process for its preparation |
| US5073543A (en) | 1988-07-21 | 1991-12-17 | G. D. Searle & Co. | Controlled release formulations of trophic factors in ganglioside-lipsome vehicle |
| IT1229203B (it) | 1989-03-22 | 1991-07-25 | Bioresearch Spa | Impiego di acido 5 metiltetraidrofolico, di acido 5 formiltetraidrofolico e dei loro sali farmaceuticamente accettabili per la preparazione di composizioni farmaceutiche in forma a rilascio controllato attive nella terapia dei disturbi mentali organici e composizioni farmaceutiche relative. |
| US5120548A (en) | 1989-11-07 | 1992-06-09 | Merck & Co., Inc. | Swelling modulated polymeric drug delivery device |
| US5698155A (en) | 1991-05-31 | 1997-12-16 | Gs Technologies, Inc. | Method for the manufacture of pharmaceutical cellulose capsules |
| US5580578A (en) | 1992-01-27 | 1996-12-03 | Euro-Celtique, S.A. | Controlled release formulations coated with aqueous dispersions of acrylic polymers |
| US5591767A (en) | 1993-01-25 | 1997-01-07 | Pharmetrix Corporation | Liquid reservoir transdermal patch for the administration of ketorolac |
| IT1270594B (it) | 1994-07-07 | 1997-05-07 | Recordati Chem Pharm | Composizione farmaceutica a rilascio controllato di moguisteina in sospensione liquida |
| EP0770397B1 (en) | 1995-10-18 | 2004-04-21 | Akzo Nobel N.V. | Newcastle disease virus combination vaccine |
| WO2001070677A1 (en) | 2000-03-20 | 2001-09-27 | Merck Sharp & Dohme Limited | Sulphonamido-substituted bridged bicycloalkyl derivatives |
| CA2644136A1 (en) | 2006-02-27 | 2007-09-07 | The Johns Hopkins University | Cancer treatment with gamma-secretase inhibitors |
-
2009
- 2009-12-21 AU AU2009330192A patent/AU2009330192A1/en not_active Abandoned
- 2009-12-21 JP JP2011543609A patent/JP2012513468A/ja active Pending
- 2009-12-21 EP EP09793431A patent/EP2379073A2/en not_active Withdrawn
- 2009-12-21 CA CA2747805A patent/CA2747805A1/en not_active Abandoned
- 2009-12-21 WO PCT/US2009/068937 patent/WO2010075255A2/en not_active Ceased
- 2009-12-21 US US13/140,741 patent/US9056857B2/en not_active Expired - Fee Related
-
2014
- 2014-08-18 JP JP2014165817A patent/JP2014210820A/ja not_active Withdrawn
-
2015
- 2015-06-10 US US14/735,798 patent/US20150272962A1/en not_active Abandoned