JP2012511963A5 - Device using stretchable or flexible electronic components for medical applications - Google Patents

Device using stretchable or flexible electronic components for medical applications Download PDF

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JP2012511963A5
JP2012511963A5 JP2011540921A JP2011540921A JP2012511963A5 JP 2012511963 A5 JP2012511963 A5 JP 2012511963A5 JP 2011540921 A JP2011540921 A JP 2011540921A JP 2011540921 A JP2011540921 A JP 2011540921A JP 2012511963 A5 JP2012511963 A5 JP 2012511963A5
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electrodes
stimulation
recording
circuit element
array
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Priority claimed from US12/575,008 external-priority patent/US9289132B2/en
Priority claimed from US12/616,922 external-priority patent/US8389862B2/en
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Priority claimed from PCT/US2009/067670 external-priority patent/WO2010082993A2/en
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Claims (22)

装置であって、
基板と、
前記基板上に配設される回路要素であって、前記回路要素は
記録電極のアレイであって、記録電極のアレイの少なくとも一部分が複数の神経源に電気接続するときに、前記複数の神経源から信号を受信する記録電極のアレイ、
複数の増幅器であって、各増幅器がそれぞれ前記記録電極のアレイのうちの１つの記録電極と電子通信状態にある複数の増幅器、および、
刺激電極のアレイ
を備える回路要素と、
前記記録電極のアレイおよび前記刺激電極のアレイと電子通信状態にある処理設備であって、複数の神経源からの前記信号を前記記録電極から受信し、前記刺激電極のアレイによってもたらされる刺激信号のパターンを確定するように構成される処理設備とを備える装置。 A device,
A substrate,
A circuit element disposed on the substrate, wherein the circuit element is an array of recording electrodes, wherein at least a portion of the array of recording electrodes electrically connects to a plurality of neural sources, the plurality of neural sources Array of recording electrodes to receive signals from
A plurality of amplifiers, each amplifier in electronic communication with one of the recording electrodes of the array of recording electrodes ;
A circuit element comprising an array of stimulation electrodes;
A processing facility in electronic communication with the array of recording electrodes and the array of stimulation electrodes, wherein the signals from a plurality of neural sources are received from the recording electrodes and of the stimulation signals provided by the array of stimulation electrodes And processing equipment configured to determine a pattern. 前記電気接続は物理的接触を含む請求項１に記載の装置。   The apparatus of claim 1, wherein the electrical connection comprises physical contact. 前記神経源からの前記信号を照合し、前記刺激電極に、対応する信号を第２の複数の神経に送らせるように構成されたマルチプレクサをさらに備える請求項１に記載の装置。   The apparatus of claim 1, further comprising a multiplexer configured to collate the signals from the neural source and cause the stimulation electrodes to send corresponding signals to a second plurality of nerves. 操作者が前記刺激信号のパターンを調整することを可能にするユーザインタフェースをさらに備える請求項１に記載の装置。   The apparatus of claim 1, further comprising a user interface that allows an operator to adjust the pattern of the stimulation signal. 前記基板は膨張性本体である請求項１に記載の装置。   The apparatus of claim 1, wherein the substrate is an inflatable body. 前記膨張性本体は円板である請求項５に記載の装置。   6. The apparatus of claim 5, wherein the expandable body is a disc. 前記刺激信号のパターンは動的に設定変更可能である請求項１に記載の装置。   The apparatus of claim 1, wherein the pattern of stimulation signals is dynamically configurable. 前記処理設備は、前記神経源の導電率に関連するデータを生成するようにさらに構成される請求項１に記載の装置。   The apparatus of claim 1, wherein the processing facility is further configured to generate data related to the conductivity of the neural source. 前記処理設備は、出力設備と電子通信状態にあり、前記出力設備に、前記神経源の導電率に関連する前記データに基づくマップを生成させる請求項８に記載の装置。   9. The apparatus of claim 8, wherein the processing facility is in electronic communication with an output facility, and the output facility generates a map based on the data related to the conductivity of the neural source. 前記回路要素は、ポリマーの薄層で被覆される請求項１に記載の装置。   The apparatus of claim 1, wherein the circuit element is coated with a thin layer of polymer. 前記回路要素は、伸張性の電気相互接続を備えるとともに３００％まで伸張可能である請求項１に記載の装置。 The apparatus of claim 1, wherein the circuitry comprises extensible electrical interconnections and is extensible up to 300%. 前記電極は、相互に分離して配置される請求項１に記載の装置。   The device according to claim 1, wherein the electrodes are arranged separately from one another. 前記回路要素は、伸張性の電気相互接続を備える請求項１に記載の装置。   The apparatus of claim 1, wherein the circuit element comprises a stretchable electrical interconnect. 前記伸張性の相互接続は、前記電極を電気接続する請求項１３に記載の装置。   The apparatus of claim 13, wherein the extensible interconnection electrically connects the electrodes. 前記回路要素は温度センサを備える請求項１に記載の装置。   The apparatus of claim 1, wherein the circuit element comprises a temperature sensor. 前記回路要素は接触センサを備える請求項１に記載の装置。   The apparatus according to claim 1, wherein the circuit element comprises a contact sensor. 前記回路要素は圧力センサを備える請求項１に記載の装置。   The apparatus of claim 1, wherein the circuit element comprises a pressure sensor. 前記基板は、前記基板の表面に連通するリザーバを備える請求項１に記載の装置。   The apparatus according to claim 1, wherein the substrate comprises a reservoir in communication with a surface of the substrate. 前記回路要素は、前記リザーバ内に収容された薬物を放出するように動作可能な弁を開放するように構成される請求項１８に記載の装置。   19. The apparatus of claim 18, wherein the circuitry is configured to open a valve operable to release a drug contained in the reservoir. 前記回路要素は、制御された方式で前記弁に前記薬物を放出させる請求項１９に記載の装置。   20. The apparatus of claim 19, wherein the circuitry causes the valve to release the drug in a controlled manner. 装置であって、A device,
基板と、A substrate,
前記基板上に配設される回路要素であって、前記回路要素はA circuit element disposed on the substrate, the circuit element being
複数の動的に設定変更可能な電極であって、A plurality of dynamically configurable electrodes,
前記複数の動的に設定変更可能な電極の第１のセットが、記録電極のアレイを提供する記録電極として構成され、前記記録電極は、複数の神経源に電気接続するとき、前記複数の神経源から信号を受信し、The first set of the plurality of dynamically configurable electrodes is configured as a recording electrode to provide an array of recording electrodes, the recording electrode being electrically connected to a plurality of neural sources. Receive the signal from the source,
前記複数の動的に設定変更可能な電極の第２のセットが、刺激電極のアレイを提供する刺激電極として構成され、かつThe second set of the plurality of dynamically configurable electrodes are configured as stimulation electrodes providing an array of stimulation electrodes, and
前記複数の動的に設定変更可能な電極のうち１つの動的に設定変更可能な電極は、その時々で記録電極または刺激電極として構成可能である複数の動的に設定変更可能な電極、およびOne of the plurality of dynamically configurable electrodes is a plurality of dynamically configurable electrodes that can be configured as a recording or stimulation electrode from time to time, and
複数の増幅器であって、各増幅器がそれぞれ１つの記録電極または１つの検知電極と電子通信状態にある複数の増幅器A plurality of amplifiers, each amplifier in electronic communication with one recording electrode or one sensing electrode respectively
を備える回路要素と、A circuit element comprising
前記複数の動的に設定変更可能な電極と電子通信状態にある処理設備であって、複数の神経源からの前記信号を前記記録電極から受信し、刺激電極によってもたらされる刺激信号のパターンを確定するように構成される処理設備とA processing facility in electronic communication with the plurality of dynamically configurable electrodes, wherein the signals from the plurality of neural sources are received from the recording electrodes and the pattern of stimulation signals provided by the stimulation electrodes is determined. And processing equipment configured to
を備える装置。A device comprising 前記複数の増幅器は検知増幅器および刺激増幅器を含み、記録電極として構成されている１つの動的に設定変更可能な電極は１つの検知増幅器と電子通信状態にあり、刺激電極として構成されている１つの動的に設定変更可能な電極は１つの刺激増幅器と電子通信状態にある請求項２１に記載の装置。The plurality of amplifiers includes a sensing amplifier and a stimulation amplifier, one dynamically configurable electrode configured as a recording electrode being in electronic communication with one sensing amplifier and configured as a stimulation electrode. 22. The apparatus according to claim 21, wherein one dynamically configurable electrode is in electronic communication with one stimulation amplifier.
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US12156808P 2008-12-11 2008-12-11
US12154108P 2008-12-11 2008-12-11
US61/121,568 2008-12-11
US61/121,541 2008-12-11
US14016908P 2008-12-23 2008-12-23
US61/140,169 2008-12-23
US12/575,008 US9289132B2 (en) 2008-10-07 2009-10-07 Catheter balloon having stretchable integrated circuitry and sensor array
US12/575,008 2009-10-07
US12/616,922 2009-11-12
US12/616,922 US8389862B2 (en) 2008-10-07 2009-11-12 Extremely stretchable electronics
PCT/US2009/067670 WO2010082993A2 (en) 2008-12-11 2009-12-11 Systems, methods, and devices using stretchable or flexible electronics for medical applications

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