JP2012510060A - シリカをベースとする活性化部分トロンボプラスチン時間アッセイにおけるｐｅｇ化血液凝固因子の活性の測定方法 - Google Patents

シリカをベースとする活性化部分トロンボプラスチン時間アッセイにおけるｐｅｇ化血液凝固因子の活性の測定方法 Download PDF

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JP2012510060A
JP2012510060A JP2011537713A JP2011537713A JP2012510060A JP 2012510060 A JP2012510060 A JP 2012510060A JP 2011537713 A JP2011537713 A JP 2011537713A JP 2011537713 A JP2011537713 A JP 2011537713A JP 2012510060 A JP2012510060 A JP 2012510060A
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peg
factor
conjugated
clotting
reaction mixture
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Japanese (ja)
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リアン・タン
ハイナー・アペラー
フィリップ・ラムゼー
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Bayer Healthcare LLC
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    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/86—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving blood coagulating time or factors, or their receptors

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Hematology (AREA)
  • Engineering & Computer Science (AREA)
  • Molecular Biology (AREA)
  • Biomedical Technology (AREA)
  • Chemical & Material Sciences (AREA)
  • Immunology (AREA)
  • Urology & Nephrology (AREA)
  • Biotechnology (AREA)
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  • General Physics & Mathematics (AREA)
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  • Investigating Or Analysing Biological Materials (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
JP2011537713A 2008-11-24 2009-11-24 シリカをベースとする活性化部分トロンボプラスチン時間アッセイにおけるｐｅｇ化血液凝固因子の活性の測定方法 Pending JP2012510060A (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US11734508P 2008-11-24 2008-11-24
US61/117,345 2008-11-24
PCT/US2009/065732 WO2010060081A1 (fr) 2008-11-24 2009-11-24 Procédé de détermination d’activité de facteur de coagulation sanguine pégylé dans un essai de temps de thromboplastine partielle activée à base de silice

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JP2012510060A true JP2012510060A (ja) 2012-04-26

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JP2011537713A Pending JP2012510060A (ja) 2008-11-24 2009-11-24 シリカをベースとする活性化部分トロンボプラスチン時間アッセイにおけるｐｅｇ化血液凝固因子の活性の測定方法

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EP (1) EP2368124A4 (fr)
JP (1) JP2012510060A (fr)
CA (1) CA2744340A1 (fr)
WO (1) WO2010060081A1 (fr)

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* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN102741275B (zh) 2009-08-24 2016-08-03 阿穆尼克斯运营公司 凝血因子ix组合物及其制备和使用方法
US20140309171A1 (en) * 2011-11-22 2014-10-16 Universite Catholique De Louvain Marker for blood coagulation
EA035323B1 (ru) 2012-01-12 2020-05-28 Биовератив Терапьютикс Инк. Полипептиды химерного фактора viii и их применение
BR112014019901A8 (pt) 2012-02-15 2018-01-02 Biogen Idec Inc Proteínas de fator viii recombinante
KR102097263B1 (ko) 2012-02-15 2020-04-06 바이오버라티브 테라퓨틱스 인크. Viii 인자 조성물 및 이를 제조하고 사용하는 방법
SI2882450T1 (sl) 2012-07-11 2020-02-28 Bioverativ Therapeutics Inc. Kompleks faktorja VIII z XTEN in s proteinom von Willebrandovega faktorja in njegove uporabe
EP3013359A4 (fr) * 2013-06-28 2017-01-25 Biogen MA Inc. Lieur clivable par la thrombine
NZ713904A (en) * 2013-06-28 2022-02-25 Bioverativ Therapeutics Inc Thrombin cleavable linker with xten and its uses thereof
WO2015023891A2 (fr) 2013-08-14 2015-02-19 Biogen Idec Ma Inc. Fusions de facteur vii-xten et leurs utilisations
PL4176894T3 (pl) 2014-01-10 2024-07-22 Bioverativ Therapeutics Inc. Białka chimeryczne czynnika VIII i ich zastosowania
WO2016049545A1 (fr) 2014-09-26 2016-03-31 Abbott Point Of Care Inc. Dispositif de cartouche à un seul canal pour des analyses de coagulation dans des échantillons de fluide
EP3198281B1 (fr) 2014-09-26 2023-01-25 Abbott Point Of Care, Inc. Formulations d'acide ellagique pour une utilisation dans des tests de coagulation
WO2016049527A1 (fr) 2014-09-26 2016-03-31 Abbott Point Of Care Inc. Dispositif de cartouche avec système fluidique segmenté pour effectuer des essais de coagulation dans des échantillons liquides
US10247741B2 (en) 2014-09-26 2019-04-02 Abbott Point Of Care Inc. Microfabricated device with micro-environment sensors for assaying coagulation in fluid samples
CN107107057B (zh) 2014-09-26 2020-12-15 雅培医护站股份有限公司 用于流体样本中的凝结测定的盒设备识别
EP3198270A1 (fr) 2014-09-26 2017-08-02 Abbott Point Of Care, Inc. Dispositif cartouche avec jonctions fluidiques pour mesures de coagulation dans des échantillons de fluide
US9903877B2 (en) 2014-09-26 2018-02-27 Abbott Point Of Care Inc. Sensors for assaying coagulation in fluid samples
IL257231B (en) 2015-08-03 2022-09-01 Bioverativ Therapeutics Inc Factor ix fusion proteins and methods for their preparation and use
CN108344875B (zh) * 2017-01-22 2021-11-02 上海长岛生物技术有限公司 提高活化部分凝血活酶时间试剂对肝素敏感性的方法及用途
MA52630A (fr) 2018-05-18 2021-05-26 Bioverativ Therapeutics Inc Procédés de traitement de l'hémophilie a

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP1745062B1 (fr) * 2004-04-22 2014-06-04 Regado Biosciences, Inc. Modulateurs ameliores des facteurs de coagulation
JP2007538248A (ja) * 2004-05-20 2007-12-27 インバーネス・メデイカル・スウイツツアーランド・ゲゼルシヤフト・ミツト・ベシユレンクテル・ハフツング 血液の凝固を検出するためのデバイスと方法
PL2371856T3 (pl) * 2004-11-12 2022-08-22 Bayer Healthcare Llc Ukierunkowana na miejsce modyfikacja czynnika VIII
CN101226201B (zh) * 2008-02-05 2011-05-11 长安大学 活化部分凝血活酶时间(aptt)测定试剂

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EP2368124A4 (fr) 2012-09-19
EP2368124A1 (fr) 2011-09-28
CA2744340A1 (fr) 2010-05-27
WO2010060081A1 (fr) 2010-05-27

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