EP2368124A4 - Procédé de détermination d'activité de facteur de coagulation sanguine pégylé dans un essai de temps de thromboplastine partielle activée à base de silice - Google Patents

Procédé de détermination d'activité de facteur de coagulation sanguine pégylé dans un essai de temps de thromboplastine partielle activée à base de silice

Info

Publication number
EP2368124A4
EP2368124A4 EP09828376A EP09828376A EP2368124A4 EP 2368124 A4 EP2368124 A4 EP 2368124A4 EP 09828376 A EP09828376 A EP 09828376A EP 09828376 A EP09828376 A EP 09828376A EP 2368124 A4 EP2368124 A4 EP 2368124A4
Authority
EP
European Patent Office
Prior art keywords
silica
blood coagulation
coagulation factor
factor activity
partial thromboplastin
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Withdrawn
Application number
EP09828376A
Other languages
German (de)
English (en)
Other versions
EP2368124A1 (fr
Inventor
Liang Tang
Heiner Apeler
Philip Ramsey
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Bayer Healthcare LLC
Original Assignee
Bayer Healthcare LLC
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Bayer Healthcare LLC filed Critical Bayer Healthcare LLC
Publication of EP2368124A1 publication Critical patent/EP2368124A1/fr
Publication of EP2368124A4 publication Critical patent/EP2368124A4/fr
Withdrawn legal-status Critical Current

Links

Classifications

    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/86—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving blood coagulating time or factors, or their receptors

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Hematology (AREA)
  • Engineering & Computer Science (AREA)
  • Molecular Biology (AREA)
  • Biomedical Technology (AREA)
  • Chemical & Material Sciences (AREA)
  • Immunology (AREA)
  • Urology & Nephrology (AREA)
  • Biotechnology (AREA)
  • Microbiology (AREA)
  • Cell Biology (AREA)
  • Food Science & Technology (AREA)
  • Medicinal Chemistry (AREA)
  • Physics & Mathematics (AREA)
  • Analytical Chemistry (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • General Physics & Mathematics (AREA)
  • Pathology (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
EP09828376A 2008-11-24 2009-11-24 Procédé de détermination d'activité de facteur de coagulation sanguine pégylé dans un essai de temps de thromboplastine partielle activée à base de silice Withdrawn EP2368124A4 (fr)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US11734508P 2008-11-24 2008-11-24
PCT/US2009/065732 WO2010060081A1 (fr) 2008-11-24 2009-11-24 Procédé de détermination d’activité de facteur de coagulation sanguine pégylé dans un essai de temps de thromboplastine partielle activée à base de silice

Publications (2)

Publication Number Publication Date
EP2368124A1 EP2368124A1 (fr) 2011-09-28
EP2368124A4 true EP2368124A4 (fr) 2012-09-19

Family

ID=42198546

Family Applications (1)

Application Number Title Priority Date Filing Date
EP09828376A Withdrawn EP2368124A4 (fr) 2008-11-24 2009-11-24 Procédé de détermination d'activité de facteur de coagulation sanguine pégylé dans un essai de temps de thromboplastine partielle activée à base de silice

Country Status (4)

Country Link
EP (1) EP2368124A4 (fr)
JP (1) JP2012510060A (fr)
CA (1) CA2744340A1 (fr)
WO (1) WO2010060081A1 (fr)

Families Citing this family (19)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20110046060A1 (en) 2009-08-24 2011-02-24 Amunix Operating, Inc., Coagulation factor IX compositions and methods of making and using same
WO2013076157A1 (fr) * 2011-11-22 2013-05-30 Universite Catholique De Louvain Marqueur pour la coagulation sanguine
CN111499760A (zh) 2012-01-12 2020-08-07 比奥贝拉蒂治疗公司 嵌合因子viii多肽及其用途
SI2822577T1 (sl) 2012-02-15 2019-07-31 Bioverativ Therapeutics Inc. Rekombinantni proteini faktorja VIII
US10421798B2 (en) 2012-02-15 2019-09-24 Bioverativ Therapeutics Inc. Factor VIII compositions and methods of making and using same
CN110054699A (zh) 2012-07-11 2019-07-26 比奥贝拉蒂治疗公司 具有xten和血管性血友病因子蛋白的因子viii复合物、及其用途
MX2015016567A (es) * 2013-06-28 2016-03-31 Biogen Ma Inc Enlazador escindible por trombina con xten y usos del mismo.
US20160229903A1 (en) * 2013-06-28 2016-08-11 Biogen Ma Inc. Thrombin cleavable linker
TW202003554A (zh) 2013-08-14 2020-01-16 美商百歐維拉提夫治療公司 因子ｖｉｉｉ－ｘｔｅｎ融合物及其用途
CN117106095A (zh) 2014-01-10 2023-11-24 比奥贝拉蒂治疗公司 因子viii嵌合蛋白及其用途
WO2016049506A1 (fr) 2014-09-26 2016-03-31 Abbott Point Of Care Inc. Capteurs pour le dosage de la coagulation dans des échantillons de fluides
US10048282B2 (en) 2014-09-26 2018-08-14 Abbott Point Of Care Inc. Cartridge device with fluidic junctions for coagulation assays in fluid samples
US10247741B2 (en) 2014-09-26 2019-04-02 Abbott Point Of Care Inc. Microfabricated device with micro-environment sensors for assaying coagulation in fluid samples
EP3198281B1 (fr) 2014-09-26 2023-01-25 Abbott Point Of Care, Inc. Formulations d'acide ellagique pour une utilisation dans des tests de coagulation
EP3198272B1 (fr) 2014-09-26 2022-04-06 Abbott Point Of Care, Inc. Identification de dispositif de cartouche pour analyses de coagulation dans des échantillons de fluide
CN107107056B (zh) 2014-09-26 2020-04-14 雅培医护站股份有限公司 用于流体样本中的凝结测定的单通道盒设备
EP3197603A1 (fr) 2014-09-26 2017-08-02 Abbott Point of Care Inc. Dispositif de cartouche avec système fluidique segmenté pour effectuer des essais de coagulation dans des échantillons liquides
US10745680B2 (en) 2015-08-03 2020-08-18 Bioverativ Therapeutics Inc. Factor IX fusion proteins and methods of making and using same
CN108344875B (zh) * 2017-01-22 2021-11-02 上海长岛生物技术有限公司 提高活化部分凝血活酶时间试剂对肝素敏感性的方法及用途

Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN101226201A (zh) * 2008-02-05 2008-07-23 长安大学 活化部分凝血活酶时间(aptt)测定试剂

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN103045601B (zh) * 2004-04-22 2015-04-01 雷加多生物科学公司 改良的凝血因子调节物
JP2007538248A (ja) * 2004-05-20 2007-12-27 インバーネス・メデイカル・スウイツツアーランド・ゲゼルシヤフト・ミツト・ベシユレンクテル・ハフツング 血液の凝固を検出するためのデバイスと方法
KR101483917B1 (ko) * 2004-11-12 2015-01-16 바이엘 헬스케어 엘엘씨 Ｆｖｉｉｉ의 부위 지향 변형

Patent Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN101226201A (zh) * 2008-02-05 2008-07-23 长安大学 活化部分凝血活酶时间(aptt)测定试剂

Non-Patent Citations (3)

* Cited by examiner, † Cited by third party
Title
DATABASE WPI Week 200904, Derwent World Patents Index; AN 2009-A80942 *
M.J. RAY ET AL: "A comparison of two APTT reagents which use silica activators", CLINICAL & LABORATORY HAEMATOLOGY, vol. 11, no. 3, 1 September 1989 (1989-09-01), pages 221 - 232, XP055034678, ISSN: 0141-9854, DOI: 10.1111/j.1365-2257.1989.tb00212.x *
See also references of WO2010060081A1 *

Also Published As

Publication number Publication date
WO2010060081A1 (fr) 2010-05-27
EP2368124A1 (fr) 2011-09-28
JP2012510060A (ja) 2012-04-26
CA2744340A1 (fr) 2010-05-27

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